Cardiovascular Research Priority Area

Active

5/7/20 → 1/11/24

Project: Research project

Mechanisms of Cardiac Remodeling Triggered by Gestational Diabetes

Despa, S. & Despa, F.

National Heart Lung and Blood Institute

5/1/20 → 4/30/24

Project: Research project

Anticoagulation in ICH Survivors for Prevention and Recovery (ASPIRE)

Gangadhara, S. & Pettigrew, L.

University of Cincinnati

4/30/20 → 4/30/24

Project: Research project

The Amylin Dyshomeostasis Hypothesis of Vascular Contributions to Cognitive Impairment and Dementia (VCID)

Despa, F., Abner, E., Despa, S., Goldstein, L., Jicha, G. & Wilcock, D.

National Institute of Neurological Disorders & Stroke

4/1/20 → 3/31/25

Project: Research project

BIO-LIBRA: Analysis of Both Sex and Device Specific Factors on Outcomes in Patients with Non-Ischemic Cardiomyopathy

Hesselson, A.

Biotronik Incorporated

11/22/19 → 7/4/24

Project: Research project

Pre-Clinical Efficacy of a Selective p38MAPK Inhibitor in a Model of Comorbid Alzheimer/Vascular Pathology

Van Eldik, L., Fardo, D., Morganti, J., Norris, C. & Lin, A. L.

National Institute on Aging

8/15/19 → 3/31/24

Project: Research project

Macrophage Migration Inhibitory Factor and Urinary Pain

Daugherty, A.

Lexington Biomedical Research Institute

7/1/19 → 12/31/23

Project: Research project

ARCADIA-CSI: Cognition and Silent Infarcts

Das, S. & Pettigrew, L.

University of Cincinnati

7/1/19 → 1/8/24

Project: Research project

A Randomized, Double Blinded Controlled Parallel Group Non-inferiority, Phase III Study to Evaluate the Efficacy and Safety of the INTERCEPT Blood System for Red Blood Cells in Patients undergoing Complex Cardiac Surgery Procedures (ReCePI)

Sekela, M.

Cerus Corporation

5/24/19 → 8/3/24

Project: Research project

Computer Modeling of Myosin Binding Protein C and its Effect on Cardiac Contraction

Campbell, K.

Case Western Reserve

4/1/19 → 3/31/24

Project: Research project

Transcriptional Regulation of KCNH2

Delisle, B., McCarthy, J., Satin, J. & Stumpf, E.

National Heart Lung and Blood Institute

3/8/19 → 2/28/24

Project: Research project

Social Network Analysis and Social Support Intervention for Rural Dwelling Older Adults with T2DM

Smalls, B., Borgatti, S., Moser, D., Pearce, K. & Schoenberg, N.

National Institute Diabetes & Digestive & Kidney

1/1/19 → 12/31/23

Project: Research project

Therapeutic Targeting of Metabolic microRNAs as a New Treatment Paradigm for NASH

Temel, R.

Aalborg University

1/1/19 → 12/31/24

Project: Research project

Cell-Specific Actions of IL-1 / IL-1R1 Signaling Following Traumatic Brain Injury

Bachstetter, A., Morganti, J. & Norris, C.

National Institute of Neurological Disorders & Stroke

12/15/18 → 11/30/24

Project: Research project

Implementing a pharmacist-managed personalized medicine dosing protocol for beta-lactam antibiotics in critically ill patients: a prospective observational pilot study.

Thompson Bastin, M., Burgess, D., Cook, A., Flannery, A., DeSalvo, A., Morris, P., Neyra Lozano, J., Schadler, A. & Schuler, E.

American Society of Health-System Pharmacists

7/1/18 → 1/30/24

Project: Research project

HDAC6 Regulation of ICAM-1 Expression and Endothelial Inflammatory Signaling in Sepsis

Fu, J.

National Heart Lung and Blood Institute

6/15/18 → 4/30/24

Project: Research project

PFO PAS: AMPLATZER PFO Occluder Post Approval Study

Gurley, J.

St Jude Business Services Incorporated

5/25/18 → 7/10/24

Project: Research project

BeAT HF: Barostim Neo - Baroreflex Activation Therapy for Heart Failure

Hesselson, A.

CVRx Inc

12/4/17 → 4/24/24

Project: Research project

Cardiovascular, Immune and Psychosocial Benefits of Reduced Cocaine Use

Stoops, W., Adatorwovor, R., Aguilar, D., Havens, J., Hays, L., Lile, J., Rush, C., Segerstrom, S., Smyth, S. & Venditto, V.

National Institute on Drug Abuse

9/1/17 → 5/31/24

Project: Research project

AMPLATZER Amulet Left Atrial Appendage Occluder

Gurley, J.

St Jude Medical Incorporated

3/28/17 → 8/11/24

Project: Research project

Corazón de la Familia (Heart of the Family)

Mudd, G., Chung, M., Lennie, T., Moser, D., Rayens, M. K., Whayne, T., Smyth, S. & Whayne, T.

National Institute of Nursing Research

3/2/17 → 12/31/23

Project: Research project

COMPASSION 3: Congenital Multicenter Trial of Pulmonic Valve Dysfunction Studying the

Leventhal, A., Gurley, J. & Schneider, D.

Edwards Lifesciences

9/7/16 → 9/1/24

Project: Research project

SPYRAL HTN ON MEDS

Kotter, J. & Ziada, K.

Medtronics Inc

6/22/15 → 7/7/24

Project: Research project

SPYRAL HTN OFF Meds

Kotter, J. & Ziada, K.

Medtronics Inc

6/22/15 → 7/7/24

Project: Research project

PRESERVE-Clinical Study to Evaluate the Safety and Effectiveness of the Zenith Branch Endovascular Graft-Iliac Bifurcation

Minion, D.

Cook Incorporated

2/13/15 → 6/7/24

Project: Research project

Epidemiologic and Biostatistical Support to AlphaNet

Choate, R., Browning, S., Mannino, D. & Gan, W.

AlphaNet Incorporated

1/1/15 → 6/30/24

Project: Research project

FEAT: Framing Eighteen coils in cerebral Aneurysms Trial

Fraser, J.

Vanderbilt University Medical Center

7/12/13 → 1/16/24

Project: Research project

Role of Impaired Cognitive States & Risk Factors in Conversion to Mixed Dementias

Kryscio, R., Fardo, D., Moga, D., Nelson, P., Schmitt, F. & Abner, E.

National Institute on Aging

9/1/11 → 1/31/24

Project: Research project

Self-Regulation and Brain and Cognitive Health in Older Adults

Gold, B., Johnson, N., Karr, J., Lutz, C., McGavran, M., Schmitt, F., Westgate, P., Segerstrom, S. & Berry, D.

National Institute on Aging

7/15/06 → 3/31/24

Project: Research project

Finished

Targeting aberrant glycogen metabolism in CLN3 disease

Wang, Q. & Gentry, M.

4/1/22 → 3/31/23

Project: Research project

Developing a novel therapy for CLN3 disease-related neurological deficits

Wang, Q., Norris, C., O'Hara, B., Sunderam, S. & McLouth, C.

12/1/21 → 11/30/22

Project: Research project

Developing a novel therapy for CLN3 disease-associated neurological deficits

Wang, Q., Norris, C., O'Hara, B. & Sunderam, S.

2/1/21 → 1/31/22

Project: Research project

A Randomized, Double-Blind, Placebo-Controlled Proof-of-Concept Study to Assess the Safety and Efficacy of Elezanumab in Acute Ischemic Stroke

Hatton, K., Lee, J. & Swafford, K.

AbbVie Incorporated

6/24/20 → 3/14/22

Project: Research project

Implementing a Novel, Multimodal Technique for Monitoring Cerebrovascular Hemodynamics in Mice as a Diagnostic and Prognostic Tool for Single and Repeated Mild TBI

Saatman, K., Chen, L., Gentry, M., Huang, C., Yu, G., Huang, C. & Sun, R.

National Institute of Neurological Disorders & Stroke

6/1/20 → 5/31/23

Project: Research project

Fellowship for Peng: Cardiomyocyte phenotype drives enhanced AMI recovery in spiny mice

Abdel-Latif, A., Satin, J., Seifert, A. & Smyth, S.

National Heart Lung and Blood Institute

6/1/20 → 8/31/20

Project: Research project

Statins Use in Intracerebral Hemorrhage Patients (SATURN)

Pettigrew, L.

4/30/20 → 7/26/23

Project: Research project

Diabetes, Glucose Metabolism, and Neuroplasticity in the Vagal Complex

Smith, B. & Gerhardt, G.

National Institute Diabetes & Digestive & Kidney

4/15/20 → 7/31/21

Project: Research project

Rethinking Repair: Long-Term Adaptive Immunity Supports Functional Recovery for Stroke Patients

Stowe, A., Fraser, J., Nelson, P. & Pennypacker, K.

American Heart Association

4/1/20 → 3/31/21

Project: Research project

Platelet Exocytosis and Endocytosis in Thrombosis and Immunity

Whiteheart, S. & Garvy, B.

National Heart Lung and Blood Institute

4/1/20 → 3/31/21

Project: Research project

COBRE in Pharmaceutical Research and Innovation

Thorson, J., Adams, V., Awuah, S., Burgess, D., Dwoskin, L., Feola, D., Garneau-Tsodikova, S., Glazer, E., Grady, M., Kolesar, J., Korotkov, K., Korotkova, N., Leggas, M., Mahmoud, K. A., Pack, D., Prisinzano, T., Richards, C., Rohr, J., Shaffer, C., Stevenson, B., Tiruvannamalai Annam, R., Van Lanen, S., Venditto, V., Zhan, C., Daugherty, A., Graf, G., Sviripa, V., Watt, D. & Webb, N.

National Institute of General Medical Sciences

3/1/20 → 1/31/21

Project: Research project

LT3001-201: A Phase IIa, Double-Blind, Single Dose, Randomized, Placebo-Controlled Study to Evaluate the Safety, Tolerability, and Potential Efficacy of LT3001 Drug Product in Subjects with Acute Ischemic Stroke (AIS)

Pettigrew, L.

1/22/20 → 10/6/21

Project: Research project

The Atherosclerosis Risk in Communities (ARIC) Study

Kucharska-Newton, A.

11/15/19 → 11/14/20

Project: Research project

Influence of Dietary Nitrogen on Hind Limb Ischemia

Suckow, M.

Cook Regentec LLC

10/31/19 → 2/1/23

Project: Research project

A Prospective, Multi-Center, Single Arm Study to Obtain "Real World" Clinical Data and Characterize the Acute and Long-Term Performance of the Micrusframe and Galaxy Coils for the Endovascular Treatment of Intracranial Aneurysms

Fraser, J.

Cerenovus Incorporated

10/18/19 → 3/2/21

Project: Research project

Assessment of the CARILLON Mitral Contour System in Treating Functional Mitral Regurgitation Associated with Heart Failure

Gurley, J.

Cardiac Dimensions Incorporated

10/16/19 → 12/15/22

Project: Research project

Fat Nerve Recording in Mice

Loria Kinsey, A.

American Physiological Society

10/1/19 → 10/31/21

Project: Research project

Healthy Kentucky Research Building Fit-up for Vascular Research

Cassis, L., Daugherty, A., Miller, G., Van Eldik, L. & Zhang, G.

Office of the Director

9/23/19 → 10/31/21

Project: Research project

Understanding the role of anti-apolipoprotein A-I antibodies in atherosclerotic cardiovascular disease

Venditto, V., Daugherty, A., Temel, R. & Charnigo, R.

National Heart Lung and Blood Institute

9/20/19 → 6/30/20

Project: Research project

A Novel Mechanism of Immunosuppression in Sepsis: Depletion of Monocytes and Macrophages

Li, Z., Morris, P., Wei, Y. & Li, X.

National Institute of General Medical Sciences

9/20/19 → 11/30/21

Project: Research project

NRSA Fellowship for Chen: Mechanisms of Renin Angiotensin Modulation in Thoracic Aortic Aneurysms

Daugherty, A. & Chen, Z.

National Heart Lung and Blood Institute

9/1/19 → 8/31/20

Project: Research project

Cardiovascular Research Priority Area

Grants and Contracts

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