Cardiovascular Research Priority Area

Grants and Contracts

Grants and Contracts per year 1996 2013 2014 2015 2016 2017 2018 2019 2025

• 44 Active
• 547 Finished

Grants and Contracts per year

Search results

• DGB-01 Effects on Endurance Exercise

  Reid, M.

  11/7/11 → 10/31/13

  Project: Research project

• Diabetes, Glucose Metabolism, and Neuroplasticity in the Vagal Complex

  Smith, B. & Gerhardt, G.

  National Institute Diabetes & Digestive & Kidney

  4/15/20 → 7/31/21

  Project: Research project

  • Glucose 100%
  • Diabetes 100%
  • Neuron 50%
  • Gamma-Aminobutyric Acid 30%
  • Neuroplasticity 20%

• Disparities in Patterns of Recurrent Stroke in the Elderly

  Goldstein, L.

  Yale University

  4/1/18 → 3/31/23

  Project: Research project

  • Apoplexy 100%
  • Disparity 100%
  • Development 100%
  • Clinical Feature 50%
  • Exercise 50%

• Don't Lose Sight of the Importance of Eye Exams-Using Telehealth in Primary Care Centers to Extend Access to Diabetic Retinopathy (DR) Screening

  Sprang, R., Sprang, R. & Higgins, E.

  Health Resources and Services Administration

  9/1/13 → 8/31/15

  Project: Research project

  • Patient 100%
  • Diabetes 84%
  • Diabetic Retinopathy 53%
  • Primary Health Care 53%
  • Screening 46%

• Don't Lose Sight of the Importance of Eye Exams-Using Telehealth in Primary Care Centers to Extend Access to Diabetic Retinopathy (DR) Screening

  Sprang, R., Sprang, R. & Higgins, E.

  Health Resources and Services Administration

  9/1/13 → 9/1/14

  Project: Research project

  • Patient 100%
  • Diabetes 84%
  • Diabetic Retinopathy 53%
  • Primary Health Care 53%
  • Screening 46%

• DPP in Hispanic and Non-Hispanic Women with a History of GDM

  Ashford, K. & Hieronymus, L.

  KY Department for Public Health

  9/1/15 → 6/30/16

  Project: Research project

  • Woman 100%
  • Diabetes Mellitus 62%
  • Hispanic 50%
  • Diabetes Prevention 37%
  • Impaired Glucose Tolerance 25%

• DPP IN HISPANIC AND NON-HISPANIC WOMEN WITH A HISTORY OF GDM

  Ashford, K. & Hieronymus, L.

  KY Department for Public Health

  7/1/16 → 6/30/17

  Project: Research project

  • Woman 100%
  • Diabetes Mellitus 62%
  • Hispanic 50%
  • Diabetes Prevention 37%
  • Impaired Glucose Tolerance 25%

• DS1040-ASSENT: A Phase 1B/2, Multi-Center, Double-Blind, Placebo-Controlled, Randomized, Single-Ascending Dose Study to Assess the Safety, Pharmacokinetics, and Pharmacodynamics of DS-1040B in Subjects with Acute Ischemic Stroke

  Pettigrew, L.

  9/15/17 → 8/22/19

  Project: Research project

• Early detection and prevention of mild cognitive impairment due to cerebrovascular disease

  Jicha, G., Abner, E., Andersen, A., Biddle, M., Dobbs, M., Han, D., Kryscio, R., Nelson, P., Neltner, J., Schmitt, F., Smith, C. & Moser, D.

  National Institute of Nursing Research

  9/26/12 → 6/30/16

  Project: Research project

  • Cerebrovascular Disease 100%
  • Comprehension 40%
  • Brain 40%
  • Cognition 40%
  • Patient 20%

• Early Detection and Prevention of Mild Cognitive Impairment Due to Cerebrovascular Disease

  Jicha, G., Abner, E., Andersen, A., Biddle, M., Dobbs, M., Han, D., Kryscio, R., Nelson, P., Neltner, J., Schmitt, F., Smith, C. & Moser, D.

  National Institute of Nursing Research

  9/26/12 → 6/30/18

  Project: Research project

  • Cerebrovascular Disease 100%
  • Comprehension 40%
  • Brain 40%
  • Cognition 40%
  • Patient 20%

• Early Life Stress & Chronic Control of Blood Pressure

  Loria Kinsey, A., Cassis, L. & Osborn, J.

  National Heart Lung and Blood Institute

  9/23/13 → 7/31/16

  Project: Research project

  • Multiple Sclerosis 100%
  • Reverse Transcription Polymerase Chain Reaction 100%
  • Western Blot 100%
  • Adipose Tissue 75%
  • Renin Angiotensin Aldosterone System 50%

• Early Use of Rosuvastatin in Acute Coronary Syndromes: Targeting Platelet-Leukocyte Interactions

  Smyth, S., Bailey, A., Campbell, C. & Charnigo, R.

  AstraZeneca Pharmaceuticals AB

  5/2/11 → 4/30/14

  Project: Research project

• Effectiveness of Pharmacist-Driven Diuresis in the Intensive Care Unit

  Turpin, B., Flannery, A., Kelly, A., Laine, M., Laine, M., Morris, P. & Thompson Bastin, M.

  American Society of Health-System Pharmacists

  6/1/18 → 2/29/20

  Project: Research project

  • Intensive Care Unit 100%
  • Pharmacist 77%
  • Volume 55%
  • Hypervolemia 44%
  • Patient 44%

• Effectiveness of the respiratory muscle training on improvement of orthostatic tolerance in individuals with spinal cord injury

  Randall, D.

  1/15/11 → 1/14/15

  Project: Research project

  • Training 100%
  • Athletic Training 87%
  • Expertise 75%
  • Student 75%
  • Grants 50%

• Effect of Early Life Stress on Obesity-Induced Hypertension in Mice

  Loria Kinsey, A., Cassis, L., Gong, M., Yiannikouris, F., Nixon, K., Osborn, J. & Pauly, J.

  National Heart Lung and Blood Institute

  12/1/17 → 11/30/23

  Project: Research project

  • Adipose Tissue 100%
  • Obesity 50%
  • Maternal Deprivation 50%
  • Angiotensinogen 50%
  • Hypertension 50%

• Effect of empagliflozin on Na+ influx in diabetic hearts

  Despa, S.

  Boehringer Ingelheim International GmbH

  2/11/16 → 4/30/16

  Project: Research project

• Effect of Training Stimuli on Fire Ground Performance and Readiness in Firefighters.

  Abel, M.

  National Strength and Conditioning Association Foundation

  8/1/14 → 6/30/17

  Project: Research project

  • Work Efficiency 100%
  • Practitioners 28%
  • Resistance Training 28%
  • Service 14%
  • Research Project 14%

• Effects of Adipocyte ACE2 on the Development of Obesity-Hypertension

  Shoemaker, R. & Cassis, L.

  American Heart Association Great Rivers Affiliate

  1/1/17 → 12/31/17

  Project: Research project

  • Obesity 100%
  • Angiotensin Converting Enzyme 2 92%
  • Angiotensin-Converting Enzyme 2 92%
  • Hypertension 85%
  • Development 57%

• Effects of Anti-miR-33 on Atherosclerosis Regression and RCT in Nonhuman Primates

  Temel, R.

  National Heart Lung and Blood Institute

  2/1/13 → 11/30/18

  Project: Research project

  • Cholesterol 100%
  • Reverse Cholesterol Transport 62%
  • Antisense 62%
  • High-Density Lipoprotein 62%
  • Oligonucleotide 62%

• Effects of Etelcalcetide vs. Cinacalcet on Bone Cell Number and Activity, Aortic Calcification, FGF-23 and Bone Markers in Serum and their Expression in Bone of Uremic Rats

  Malluche, H. & Lima, F.

  AMGen

  5/25/18 → 5/1/20

  Project: Research project

• Effects of Family Sodium Watchers Program on Outcomes in Heart Failure Patient-Family Caregiver Dyads

  Chung, M., Lennie, T., Moser, D. & Rayens, M. K.

  National Institute of Nursing Research

  9/26/14 → 7/31/20

  Project: Research project

  • Sodium 100%
  • Patients 57%
  • Diet 52%
  • Family 52%
  • Caregiver 47%

• Effects of ferric citrate hydrate on aortic calcification, bone, and FGF-23 in an animal model of chronic kidney failure

  Malluche, H. & Monier Faugere, M.

  Keryx Biopharmaceuticals Incorporated

  5/1/15 → 7/31/16

  Project: Research project

• Effects of Zortress® + Tacrolimus (everolimua) versus Standard Immunosuppression therapy on Progression of Coronary Artery Calcifications in Patients with Renal Transplantation

  Malluche, H. & Gedaly, R.

  Novartis (domestic)

  12/16/11 → 12/31/13

  Project: Research project

• Emanate: Apixiban in Cardioversion

  Messerli, A.

  PPD Development Inc

  11/7/14 → 10/31/17

  Project: Research project

• Endocrine disruptor mediated activation of PXR causes dyslipidemia

  Zhou, C., Cassis, L., Charnigo, R., Morris, A., Park, S. H. & Sui, Y.

  National Institute of Environmental Health Sciences

  9/26/13 → 6/30/16

  Project: Research project

  • Endocrine Disruptor 100%
  • Pregnane X Receptor 89%
  • Pregnane 89%
  • Mouse 40%
  • Hyperlipidemia 40%

• Endocrine disruptor mediated activation of PXR causes dyslipidemia

  Zhou, C., Cassis, L., Charnigo, R., Hennig, B., Morris, A., Park, S. H., Sui, Y. & Van Der Westhuyzen, D.

  National Institute of Environmental Health Sciences

  9/26/13 → 6/30/14

  Project: Research project

  • Endocrine Disruptor 100%
  • Pregnane X Receptor 89%
  • Pregnane 89%
  • Mouse 40%
  • Hyperlipidemia 40%

• Endocrine Disruptor Mediated Activation of PXR Causes Dyslipidemia

  Zhou, C., Cassis, L., Charnigo, R., Morris, A., Park, S. H. & Sui, Y.

  National Institute of Environmental Health Sciences

  9/26/13 → 7/31/19

  Project: Research project

  • Endocrine Disruptor 100%
  • Pregnane X Receptor 89%
  • Pregnane 89%
  • Mouse 40%
  • Hyperlipidemia 40%

• Endothelial Cell Dysregulation in Neovascular AMD

  Kleinman, M.

  9/1/11 → 8/31/16

  Project: Research project

  • Independence 100%
  • Athletic Training 100%
  • Development 100%
  • Proliferative Vitreoretinopathy 66%
  • Wet Macular Degeneration 66%

• Endovascular Interventions with AngioMax: The ENDOMAX Trial

  Saha, S.

  Medicines Company

  12/16/14 → 4/5/16

  Project: Research project

• Energy metabolism in platelets during thrombus formation

  Wang, Q. & Whiteheart, S.

  9/1/15 → 12/31/16

  Project: Research project

• Enhance CRT

  Darrat, Y. & Morales, G.

  5/23/14 → 10/2/18

  Project: Research project

• EnligHTN IV

  Ziada, K.

  1/1/14 → 3/30/14

  Project: Research project

• Epidemiologic and Biostatistical Support to AlphaNet

  Choate, R., Browning, S., Mannino, D. & Gan, W.

  AlphaNet Incorporated

  1/1/15 → 12/31/22

  Project: Research project

  • Patient 100%
  • Combination Therapy 75%
  • Researcher 25%
  • Inflatable Penis Prosthesis 25%
  • Inpatient 25%

• Epigenetic Determinants of Left Ventricular Structure and Function in Hypertensive African Americans

  Arnett, D.

  2/1/16 → 1/31/17

  Project: Research project

  • Genetic Epidemiology 100%
  • Epigenetics 83%
  • Genetics 50%
  • Phenotype 50%
  • Heritability 33%

• Epigenetic Determinants of Lipid Response to Dietary Fat and Fenofibrate

  Arnett, D.

  6/30/16 → 5/31/18

  Project: Research project

  • Fenofibrate 100%
  • Epigenomics 80%
  • Dietary Fat 80%
  • Next Generation Sequencing 80%
  • Epigenetics 80%

• Epigenetic Regulation of Inflammatory Gene Expression by Telomerase

  Bruemmer, D. & Charnigo, R.

  National Heart Lung and Blood Institute

  9/27/12 → 12/31/15

  Project: Research project

  • Macrophage 100%
  • Telomerase 100%
  • Gene Expression 83%
  • Atherosclerosis 83%
  • Chromatin 66%

• Essential Siemens Prisma Fit Upgrade for the University of Kentucky 3T Research Scanner

  Smith, C., Andersen, A., Bardo, M., Bauer, J., Cassis, L., Hardy, P., Head, E., Jicha, G., Johnson, N., Kelly, T., Meacham, B., Milich, R., Noehren, B., Powell, D., Temel, R., Thomas, D., Van Eldik, L., Bailey, N. & Vandsburger, M.

  Office of the Director

  3/21/17 → 3/20/18

  Project: Research project

  • Tenidap 100%
  • Biomedical Research 66%
  • Clinical Neuroscience 33%
  • Introspection 33%
  • White Matter 33%

• Establishing a Bioexclusion Barrier in the Combs Cancer Research Building

  Stills, H., Ambati, J., Daugherty, A., Evers, B. M., Haughton, C., Kincer, J., Miller, G., Smiley, J. & Bortnick, S.

  Office of the Director

  4/1/15 → 3/31/17

  Project: Research project

  • Facilities 100%
  • Cages 46%
  • Research 38%
  • Animals 38%
  • Strain 30%

• Estrogen Regulation of Daily Metabolic Rhythms

  Pendergast, J.

  National Institute Diabetes & Digestive & Kidney

  7/1/16 → 6/30/19

  Project: Research project

  • Rhythm 100%
  • Fat 100%
  • Mouse 71%
  • Circadian Rhythm 42%
  • Estrogens 42%

• Evaluate agents with antifibrosis response in mouse models of AAA

  Lu, H.

  Merck and Company Inc

  6/3/15 → 6/2/17

  Project: Research project

• Evaluating the Effectiveness of the LifeVest Defibrillator and Imporving Methods for Determining the Use of Implantable Cardioverter Defibrillators (The VEST/PREDICTS Study)

  Hesselson, A., Darrat, Y. & Elayi, S.

  University of California San Francisco

  6/1/09 → 3/14/20

  Project: Research project

• Evaluation of Compounds in LQT3 Mice

  Delisle, B.

  Human BioMolecular Research Institute

  5/15/17 → 11/15/17

  Project: Research project

  • Long QT Syndrome 100%
  • Mutation 57%
  • Mouse 42%
  • Phenotype 28%
  • Electric Potential 28%

• EVOLLUTION, A Study Comparing Angiomax (bivalirdin) to Heparin with Protamine Reversal in Patients Undergoing Off-Pump Coronary Artery Bypass (OPCAB) Surgery

  Saha, S.

  7/17/03 → 7/17/03

  Project: Research project

• Expanding Patient Applicability with PoLymer SEaling OVATion Alto StEnt Graft IDE Study

  Minion, D.

  Endologix Incorporated

  12/8/17 → 11/15/18

  Project: Research project

• Exploring the role of dyssynchrony in pediatric heart disease with MRI

  Vandsburger, M. & Charnigo, R.

  Geisinger Health System

  2/9/15 → 8/31/16

  Project: Research project

  • Tetralogy of Fallot 100%
  • Patient 75%
  • Heart Failure 75%
  • Cardiac Resynchronization Therapy 50%
  • Child 50%

• Exploring the role of dyssynchrony in pediatric heart disease with MRI

  Vandsburger, M. & Charnigo, R.

  Geisinger Health System

  2/9/15 → 8/31/15

  Project: Research project

  • Tetralogy of Fallot 100%
  • Patient 75%
  • Heart Failure 75%
  • Cardiac Resynchronization Therapy 50%
  • Child 50%

• Exploring the Role of Dyssynchrony in Pediatric Heart Disease with MRI

  Powell, D., Charnigo, R. & Vandsburger, M.

  Geisinger Health System

  2/9/15 → 8/31/18

  Project: Research project

  • Tetralogy of Fallot 100%
  • Patient 75%
  • Heart Failure 75%
  • Cardiac Resynchronization Therapy 50%
  • Child 50%

• Exploring the role of dyssynchrony in pediatric heart disease with MRI - Year 3

  Fornwalt, B., Charnigo, R., Sorrell, V. & Suever, J.

  Office of the Director

  9/25/12 → 12/31/14

  Project: Research project

  • Tetralogy of Fallot 100%
  • Patient 75%
  • Heart Failure 75%
  • Cardiac Resynchronization Therapy 50%
  • Child 50%

• External Project- Immunotherapy for Experimental Stroke for Neuro Detective International

  Bix, G. & Roberts, J.

  Neurodetective International Incorporated

  3/1/16 → 5/30/16

  Project: Research project

• FAME 3--Fractional Flow Reserve vs. Angiography for Multivessel Evaluation Trial

  Ziada, K., Abdel-Latif, A., Booth, D., Gurley, J., Leventhal, A. & Messerli, A.

  Stanford University

  6/16/16 → 6/16/18

  Project: Research project

  • Patient 100%
  • Fractional Flow Reserve 14%
  • Heart Catheterization 14%
  • Percutaneous Coronary Intervention 14%
  • Cardiac Catheterization 14%