Diabetes & Obesity Research Priority Area

Grants and Contracts

Grants and Contracts per year 1996 2013 2014 2015 2016 2017 2018 2019 2025

• 47 Active
• 389 Finished

Grants and Contracts per year

Search results

• The Role of Sin1 in Colorectal Cancer Progression

  Yang, H., Lee, E. & Wang, C.

  National Cancer Institute

  4/1/15 → 9/30/17

  Project: Research project

  • Colon 100%
  • Programmed Cell Death 83%
  • Linsidomine 83%
  • Apoptosis 83%
  • Colon Tumor 44%

• Fatty acid profile in ruminal content and blood plasma of finishing beef cattle, supplemented with different levels of marine algae.

  Harmon, D.

  Alltech Incorporated

  10/1/14 → 9/30/17

  Project: Research project

• Mechanisms of atherogenic effects of bisphenol A

  Zhou, C., Cassis, L., Hennig, B., Kern, P., Morris, A., Park, S. H. & Sui, Y.

  National Institute of Environmental Health Sciences

  4/1/14 → 9/30/17

  Project: Research project

  • 4,4' Isopropylidenediphenol 100%
  • Pregnane X Receptor 91%
  • Mouse 58%
  • Atherosclerosis 41%
  • Atherogenesis 25%

• Dietary Lipids and Lipopolysaccharide

  Kern, P., Barrett, T., Ebersole, J. & Angulo, P.

  National Institute Diabetes & Digestive & Kidney

  4/15/14 → 9/30/17

  Project: Research project

  • Lipopolysaccharide 100%
  • Serositis 63%
  • Chylomicron 54%
  • Insulin Resistance 54%
  • Intestine Flora 45%

• Reducing diabetes risk for Rural Appalachian Grandparent Headed Households

  Hatcher, J., Rayens, M. K., Schoenberg, N. & Scott, L.

  National Institute Diabetes & Digestive & Kidney

  7/1/14 → 11/30/17

  Project: Research project

  • Diabetes 100%
  • Household 66%
  • Grandparent 66%
  • Family 66%
  • Grandparent-Headed Household 66%

• University of Kentucky Center for Cancer and Metabolism

  St Clair, D., Anthony, L., Arnold, S., Black, W., Bollinger, L., Butterfield, D. A., Chaiswing, L., Chen, M., Fan, W., Gao, T., Higashi, R., Jia, J., Kyprianou, N., Lane, A., Lee, E., Long, D., Morris, A., Moseley, H., O'Connor, K., Peterson, C., Piecoro, D., Powell, D., Romond, E., St Clair, W., Thomas, D., Vanderford, N., Wang, C., Weiss, H., Wu, Y., Yu, G., Zaytseva, Y., Zhou, B., Dobrowolski, P. & Xu, R.

  National Institute of General Medical Sciences

  3/1/17 → 12/31/17

  Project: Research project

  • Malignant Neoplasm 100%
  • Metabolism 86%
  • Metabolic Pathway 86%
  • Mentoring 40%
  • Cancer Research 26%

• Health Center Cluster

  Quillen, L., Dotson, C., Fields, J., Hughes, J., Johnson, S., Miller, T., Muha, S., Piercy, J., Slone, K., Stone, D., Taylor, W., Kingery, J., Haynes, K., Hollen, M., Johnson, C. & Knox, T.

  Health Resources and Services Administration

  1/1/06 → 12/31/17

  Project: Research project

  • Communities 100%
  • Medical Centres 83%
  • Service Industries 83%
  • Population Censuses 66%
  • Poverty 66%

• Evaluation Training and Technical Assistance Activities to Increase Implementation of Evidence-based Cancer Prevention and Control

  Vanderpool, R.

  8/1/16 → 12/31/17

  Project: Research project

  • Technical Assistance 100%
  • Transdisciplinary 89%
  • Evaluation 80%
  • Control 50%
  • Teams 40%

• Effects of Adipocyte ACE2 on the Development of Obesity-Hypertension

  Shoemaker, R. & Cassis, L.

  American Heart Association Great Rivers Affiliate

  1/1/17 → 12/31/17

  Project: Research project

  • Obesity 100%
  • Angiotensin Converting Enzyme 2 92%
  • Angiotensin-Converting Enzyme 2 92%
  • Hypertension 85%
  • Development 57%

• Appalachians Together Restoring the Eating Environment (Appal-TREE): Advancing Sustainable CBPR Interventions to Improve Healthy Diet in Rural Appalachian Children

  Swanson, M., McQuerry, K., Mullins, J., Schoenberg, N., Bush, H. & Mays, G.

  National Institute on Minority Health and Health Disparities

  4/26/16 → 12/31/17

  Project: Research project

  • Intervention 100%
  • Communities 54%
  • Food 36%
  • Obesity 36%
  • Child 36%

• Adipocyte PRR Contributes to Obesity Induced Hypertension and Insulin Resistance

  Yiannikouris, F.

  7/1/13 → 12/31/17

  Project: Research project

  • Adipocyte 100%
  • Obesity 90%
  • Angiotensin II 72%
  • Insulin Resistance 72%
  • Adipose Tissue 63%

• A Novel Therapy for the Treatment of Dementia

  Murphy, M. & Niedowicz, D.

  BrightFocus Foundation

  7/1/14 → 12/31/17

  Project: Research project

  • Cognitive Disorders 100%
  • Diabetes Mellitus 100%
  • Cerebrovascular Disease 100%
  • Dementia 66%
  • Phenotype 33%

• Appalachia Community Cancer Network

  Dignan, M., Schoenberg, N., Shelton, B., Slone, M. & Webber, K.

  National Cancer Institute

  9/1/10 → 2/28/18

  Project: Research project

  • Universities 100%
  • Communities 87%
  • Cancer 75%
  • Program 62%
  • State 50%

• Triple Quadrupole Mass Spectrometer System

  Morris, A.

  3/15/17 → 3/14/18

  Project: Research project

  • Core 100%
  • Research 87%
  • Utilization 62%
  • Mass Spectroscopy 62%
  • Service 62%

• Colesevelam Oral Suspension as Monotherapy or Add-on to Metformin Therapy in Pediatric Subjects with Type 2 Diabetes Mellitus

  Thrailkill, K., Fowlkes, J., Kalaitzoglou, E. & Morales, A.

  Daiichi Sankyo Incorporated

  3/29/16 → 3/28/18

  Project: Research project

• Advancing Health Communication Research Through the KCHC-DCHC Conference Series

  Harrington, N. & Johnson, S.

  National Cancer Institute

  4/19/12 → 3/31/18

  Project: Research project

  • Health 100%
  • Interpersonal Communication 88%
  • Conferences 77%
  • Health Communication 72%
  • Communication 72%

• The Insulin/IGF-I Axis in Diabetic Osteopathy

  Fowlkes, J., Bunn, R. & Thrailkill, K.

  National Institute Diabetes & Digestive & Kidney

  5/23/14 → 3/31/18

  Project: Research project

  • Insulin 100%
  • Somatomedin C 80%
  • Knock Out 53%
  • Osteoblast 46%
  • Insulin Receptor 46%

• Ryan White Part C: Outpatient Early Intervention Services to HIV Positive Persons 2015-2017

  Thornton, A., Fanucchi, L., Forster, D., Holleman, D., Karki Maskey, M., Leedy, N., Murphy, B., Myint, T., Romanelli, F. & Schaninger, T.

  Health Resources and Services Administration

  9/30/01 → 3/31/18

  Project: Research project

  • Patient 100%
  • Hospital 64%
  • Person 30%
  • Human Immunodeficiency Virus 20%
  • Outpatient 10%

• PPAR Inhibition of Spinal Pain Transmission

  Taylor, B., Albuquerque, R. & Smith, B.

  12/18/08 → 3/31/18

  Project: Research project

  • Diabetic Neuropathy 100%
  • Methylglyoxal 100%
  • Pain 50%
  • Maturity Onset Diabetes of the Young 33%
  • Non Insulin Dependent Diabetes Mellitus 33%

• Nutrition and Superfund Chemical Toxicity

  Hennig, B., Balk, J., Bhattacharyya, D., Brewer, D., Cassis, L., Dziubla, T., Hilt, J., Hoover, A., Morris, A., Ormsbee, L., Pearson, K., Pennell, K., Stromberg, A., Swanson, H. & Gaetke, L.

  National Institute of Environmental Health Sciences

  4/7/97 → 3/31/18

  Project: Research project

  • Polychlorinated Biphenyl 100%
  • Polychlorobiphenyl 50%
  • Nutrient 33%
  • Chemical Toxicity 33%
  • Toxicity 25%

• Regulation of Blood Pressure Circadian Rhythm by Vascular Smooth Muscle BMAL1

  Gong, M., Guo, Z., Duncan, M. & Esser, K.

  National Heart Lung and Blood Institute

  5/15/12 → 4/30/18

  Project: Research project

  • Circadian Rhythm 100%
  • Blood Pressure 77%
  • Nested Gene 16%
  • Gene 16%
  • Tissue 11%

• SBIR: System for Automated Noninvasive Monitoring of Mouse Sleep and Behavior

  Sunderam, S.

  Signal Solutions LLC

  8/1/15 → 4/30/18

  Project: Research project

• Telmisartan Plus Exercise to Improve Functioning in PAD: The TELEX Trial

  Peterson, C.

  8/17/15 → 4/30/18

  Project: Research project

  • Biological Product 100%
  • Inpatient 66%
  • Fiber 33%
  • Telmisartan 33%
  • Tenidap 33%

• Epigenetic Determinants of Lipid Response to Dietary Fat and Fenofibrate

  Arnett, D.

  6/30/16 → 5/31/18

  Project: Research project

  • Fenofibrate 100%
  • Epigenomics 80%
  • Next Generation Sequencing 80%
  • Dietary Fat 80%
  • Epigenetics 80%

• Improving Anti-tumor Immunity by Targeting LDH-A Functions: Beyond the Warburg Effect

  Fan, W. & Higashi, R.

  Beth Israel Deaconess Medical Center Incorporated

  6/14/17 → 5/31/18

  Project: Research project

  • Antigen Specificity 100%
  • Metabolomics 80%
  • Experiment 60%
  • Lipid 40%
  • Glutamine 40%

• Vitamin D Contribution to Muscle Metabolic Function in the Elderly

  Thomas, D., Black, W., Bush, H., Peterson, C., Powell, D. & Yu, G.

  National Institute on Aging

  8/15/14 → 5/31/18

  Project: Research project

  • Muscle 100%
  • Vitamin D 89%
  • Aerobic Exercise 60%
  • Athletic Training 60%
  • Training 60%

• A phase 2a multi-center study of 18F-FDG PET, safety and tolerability of AZD0530 in mild Alzheimer#s disease

  Jicha, G., Bardach, S. & Murphy, R.

  University of Southern California

  7/1/15 → 5/31/18

  Project: Research project

  • Saracatinib 100%
  • Therapeutic Procedure 66%
  • Placebo 44%
  • Analysis 22%
  • Fluorodeoxyglucose F 18 22%

• Bioactive Sphingolipids and Wound Healing

  Nikolova-Karakashian, M., Liang, Y. & Deevska, G.

  Army Medical Research and Materiel Command

  8/1/16 → 5/31/18

  Project: Research project

  • Acid Sphingomyelinase 100%
  • Sphingomyelin Phosphodiesterase 100%
  • Wound Healing 42%
  • Tumor Necrosis Factor 31%
  • Diabetes Mellitus 31%

• Circadian rhythms and melatonin signaling in the aging gastrointestinal system

  Cassone, V.

  National Institute on Aging

  8/15/13 → 5/31/18

  Project: Research project

  • Melatonin 100%
  • Aging 83%
  • Circadian Rhythm 66%
  • Nested Gene 66%
  • Gene 66%

• FY18 UK Heart Disease and Stroke Prevention Project

  Berrones, A. & Riddell, M.

  KY Cabinet for Health and Family Services

  7/1/16 → 6/30/18

  Project: Research project

  • Heart Disease 100%
  • Apoplexy 100%
  • Diabetes 50%
  • Health 50%
  • Adoption 50%

• FY18 UK PRC Obesity and Tobacco Evaluation (1305 QUAD)

  Dignan, M.

  KY Department for Public Health

  7/1/16 → 6/30/18

  Project: Research project

  • Evaluation Study 100%
  • Obesity 60%
  • Prevention 60%
  • Heart Disease 20%

• Wellcare CDSMP and DSMP Project

  Feltner, F. & Baker, W.

  Comprehensive Health Management Incorporated

  12/31/16 → 6/30/18

  Project: Research project

• CHEER (TCAC)

  Sheppard-Jones, K.

  KY Cabinet for Health and Family Services

  7/1/17 → 6/30/18

  Project: Research project

  • Health 100%
  • Hypertension 69%
  • Disability 69%
  • Exercise 50%
  • Resources 50%

• Facilitator Cancer Leadership FY17 and FY18

  Knight, J. & Knight, J.

  KY Department for Public Health

  7/1/16 → 6/30/18

  Project: Research project

  • Heart Disease 100%
  • Obesity 100%
  • Health Promotion 100%
  • Public Health 100%
  • Health 100%

• UK SNAP Ed Program 2018

  Vail, A., Davis, A., Kahl, D. & Koo, J.

  KY Department of Community Based Services

  10/1/17 → 6/30/18

  Project: Research project

  • Program 100%
  • Nutrition 93%
  • Assistance 75%
  • Supplemental Nutrition Assistance Program 75%
  • Food 62%

• A Novel Anti Obesity Drug Combination as a Pharmacotherapy for Cocaine Dependence

  Rush, C., Hays, L., Lile, J., Rayapati, A., Stoops, W. & Glaser, P.

  National Institute on Drug Abuse

  9/15/12 → 6/30/18

  Project: Research project

  • Cocaine Dependence 100%
  • Bupropion 100%
  • Naltrexone 89%
  • Cocaine 50%
  • Cannabis 50%

• Neural Circuitry in the Dorsal Vagal Complex

  Smith, B. & Boychuk, C.

  6/1/01 → 6/30/18

  Project: Research project

  • Diabetes 100%
  • Glucose 53%
  • GABA Receptor 30%
  • Neuron 30%
  • Hyperglycemia 15%

• NRSA Fellowship for Brewer: Defining the Role of Laforin in Glycogen Metabolism and Lafora Disease

  Gentry, M., Brewer, M. & Vander Kooi, C.

  7/1/16 → 6/30/18

  Project: Research project

  • Glycogen 100%
  • Carbohydrate 60%
  • Mutation 60%
  • Dimerization 40%
  • Binding Domain 40%

• Efficacy and Safety of liraglutide in combination with metformin versus metformin monotherapy on glycaemic control in children and adolescents with type 2 diabetes

  Thrailkill, K., Fowlkes, J., Kalaitzoglou, E. & Morales, A.

  Novo Nordisk Pharmaceuticals Inc

  7/14/16 → 7/13/18

  Project: Research project

• NRSA T32: Pharmacology and Nutritional Sciences: Multidisciplinary Approaches for Metabolic Disease

  Webb, N. & Cassis, L.

  National Institute Diabetes & Digestive & Kidney

  8/15/00 → 7/31/18

  Project: Research project

  • Training 100%
  • Water-Electrolyte Imbalance 85%
  • Athletic Training 85%
  • Cardiovascular Disease 42%
  • Malignant Neoplasm 42%

• ASPIRE: Air Pollution: Strategies for Personalized Intervention to Reduce Exposure

  Fan, W. & Higashi, R.

  Case Western Reserve

  9/30/17 → 7/31/18

  Project: Research project

  • Glucose 100%
  • Analytical Method 50%
  • Metabolite 50%
  • Stable Isotope 50%
  • Area Under the Curve 33%

• Hyperamylinemia in Diabetic Heart Disease: Mechanisms, Responses, and Prevention

  Despa, F., Cassis, L., Daugherty, A., Despa, S., Frolov, A. & Liu, M.

  National Heart Lung and Blood Institute

  8/23/13 → 7/31/18

  Project: Research project

  • Amylin 100%
  • Heart 60%
  • Oligomer 34%
  • Rat 34%
  • Calcium Ion 15%

• To Determine the Effects of Probiotic Supplementation (EquiBrew) on Immune, Metabolic and Microbiome Changes in Senior Horses

  Adams, A.

  BioBrew Ltd

  8/29/17 → 8/28/18

  Project: Research project

• Dissertation award for Corinne Gressang

  Popkin, J.

  5/5/17 → 8/31/18

  Project: Research project

  • Political Unrest 100%
  • Nuns 75%
  • Sacrifice 50%
  • Citizens 50%
  • Auxiliary 25%

• Effect of Different Fat Sources and Vitamin E Status On Antioxident Status, Carcuss Characteristics, and Meat Quality of Pigs Grown to Heavy Slaughter Weight

  Lindemann, M.

  Fats and Proteins Research Foundation Incorporated

  11/1/16 → 8/31/18

  Project: Research project

  • Pig 100%
  • Human Nutrition 80%
  • Slaughter Weight 60%
  • Slaughter 60%
  • Fatty Acids 60%

• The role of hepatic insulin resistance on SR-BI dependant HDL cholesterol uptake and metabolism

  Graf, G., Charnigo, R., Galperin, E. & Van Der Westhuyzen, D.

  National Institute Diabetes & Digestive & Kidney

  9/20/13 → 8/31/18

  Project: Research project

  • Insulin Signaling 100%
  • Cholesterol 83%
  • Randomized Controlled Trial 66%
  • Insulin Resistance 66%
  • High Density Lipoprotein Cholesterol 50%

• Get Fruved: A Peer-Led, Train-the-Trainer Social Marketing Intervention to Increase Fruit and Vegetable Intake and Prevent Childhood Obesity

  Lowe, F. & Lowe, F.

  University of Tennessee

  8/1/17 → 9/5/18

  Project: Research project

  • Fruit 100%
  • Vegetable 100%
  • Childhood Obesity 100%
  • Peers 100%

• Collaborative Environment Approaches To Reduce Obesity Disparities In Kentucky

  Vail, A., Bastin, S., Brewer, D., Cardarelli, K., Carman, A., Davis, A., Gustafson, A., Kurzynske, J., McGladrey, M., Mullins, J., Stephenson, T. & Webber, K.

  Center for Disease Control and Prevention

  9/30/14 → 9/29/18

  Project: Research project

  • Humans 100%
  • Healthy Behavior 100%
  • Physical Activity 100%
  • Time 100%
  • Family 100%

• Specialty Crop: Plate It Up! Kentucky Proud Recipe Development and Evaluation for Consumers and Producers: Healthy Meals that Serve One or Two

  Stephenson, T. & Vail, A.

  KY Department of Agriculture

  12/1/15 → 9/30/18

  Project: Research project

  • Specialty Crops 100%
  • Recipes 75%
  • Adults 50%
  • Children 50%
  • Lifestyle 25%

• Understanding SNAP and Food Security Among Low-Income Households

  Ziliak, J.

  Economic Research Service

  9/19/13 → 9/30/18

  Project: Research project

  • Households 100%
  • Supplemental Nutrition Assistance Program 100%
  • Food Security 100%
  • Research 66%
  • Human Nutrition 66%