Diabetes & Obesity Research Priority Area

Grants and Contracts

Grants and Contracts per year 1996 2013 2014 2015 2016 2017 2018 2019 2025

• 47 Active
• 389 Finished

Grants and Contracts per year

Search results

• Collaborative Environment Approaches to Reduce Obesity Disparities in Kentucky

  Vail, A., Bastin, S., Brewer, D., Cardarelli, K., Carman, A., Davis, A., Gustafson, A., Kurzynske, J., McGladrey, M., Mullins, J., Stephenson, T. & Webber, K.

  Center for Disease Control and Prevention

  9/30/14 → 9/29/17

  Project: Research project

  • Humans 100%
  • Healthy Behavior 100%
  • Physical Activity 100%
  • Time 100%
  • Family 100%

• Collaborative Environment Approaches to Reduce Obesity Disparities in Kentucky

  Vail, A., Bastin, S., Brewer, D., Cardarelli, K., Carman, A., Davis, A., Gustafson, A., Kurzynske, J., McGladrey, M., Mullins, J., Stephenson, T. & Webber, K.

  Center for Disease Control and Prevention

  9/30/14 → 9/29/15

  Project: Research project

  • Humans 100%
  • Healthy Behavior 100%
  • Physical Activity 100%
  • Time 100%
  • Family 100%

• Collaborative Environment Approaches to Reduce Obesity Disparities in Kentucky

  Vail, A., Bastin, S., Brewer, D., Cardarelli, K., Carman, A., Davis, A., Gustafson, A., Kurzynske, J., McGladrey, M., Mullins, J., Stephenson, T. & Webber, K.

  Center for Disease Control and Prevention

  9/30/14 → 9/29/16

  Project: Research project

  • Humans 100%
  • Healthy Behavior 100%
  • Physical Activity 100%
  • Time 100%
  • Family 100%

• Fatty acid profile in ruminal content and blood plasma of finishing beef cattle, supplemented with different levels of marine algae.

  Harmon, D.

  Alltech Incorporated

  10/1/14 → 9/30/17

  Project: Research project

• UK Supplemental Nutrition Assistance Program Education (SNAP-Ed)

  Vail, A. & Mullins, J.

  KY Cabinet for Health and Family Services

  10/1/14 → 6/30/16

  Project: Research project

  • Supplemental Nutrition Assistance Program Education 100%
  • Foods 60%
  • Family 60%
  • Behavior 30%
  • Human Nutrition 30%

• Cross-Sectional Analyses Investigating the Prevalence and Characteristics of Asthma-COPD Overlap Patients in the General Population Using NHANES

  Mannino, D. & Gan, W.

  10/7/14 → 2/28/16

  Project: Research project

• Effects of dietary antioxidant supplementation on DHA-enriched pork meat

  Lindemann, M. & Xiong, Y.

  Alltech Incorporated

  10/15/14 → 3/30/15

  Project: Research project

• Study on Transdermal Delivery of Human Insulin to Mice in a Cream-Based Delivery System

  COHEN, D.

  11/15/14 → 11/30/16

  Project: Research project

• First Preclinical Model of Hippocampal Sclerosis of Aging (an AD Mimic)

  Nelson, P., Fardo, D., Murphy, M. & Saatman, K.

  Alzheimers Drug Discovery Foundation

  11/15/14 → 3/1/16

  Project: Research project

  • Hippocampal Sclerosis 100%
  • Aging 91%
  • Multidrug Resistance Associated Protein 50%
  • Sulfonylurea 25%
  • Drug 25%

• Magnetic resonance imaging of early molecular changes in diabetic heart disease

  Vandsburger, M.

  11/17/14 → 10/1/15

  Project: Research project

  • Heart Failure 100%
  • Magnetic Resonance Imaging 80%
  • CD36 60%
  • Heart 40%
  • Diagnosis 40%

• Effects of KDT501 on Metabolic Features in Insulin Resistant Subjects

  Kern, P.

  Kindex Pharmaceuticals

  12/2/14 → 6/30/16

  Project: Research project

• DIVINE - Dietary Management of Glucose Variability in the ICU

  Bernard, A., Gopinath, A. & Procter, L.

  Nestle HealthCare Nutrition Incorporated

  1/13/15 → 7/12/17

  Project: Research project

• Stimulation of posttraumatic neurogenesis by IGF-1 overexpression

  Saatman, K., Sama, D. & Smith, B.

  KY Spinal Cord and Head Injury Research Trust

  1/15/15 → 12/31/20

  Project: Research project

  • Neuron 100%
  • Insulin-Like Growth Factor 1 91%
  • Traumatic Brain Injury 41%
  • Neurogenesis 41%
  • Cell Proliferation 16%

• Specialty Crop: Plate It Up! Kentucky Proud Recipe Development and Evaluation for Consumers and Producers Using Healthy Specialty Cooking Techniques with an Emphasis on Grilling

  Stephenson, T. & Vail, A.

  KY Department of Agriculture

  2/2/15 → 9/29/17

  Project: Research project

  • Specialty Crops 100%
  • Recipes 75%
  • Adults 25%
  • Lifestyle 25%
  • Children 25%

• American Association of Diabetes Educators Diabetes Prevention Program (AADE DPP)

  Ashford, K. & Hieronymus, L.

  American Association of Diabetes Educators

  4/1/15 → 3/31/16

  Project: Research project

  • Diabetes Prevention 100%
  • Recognition 31%
  • Standard 25%
  • Procedures 25%
  • Association 18%

• Ryan White Part C: Outpatient Early Intervention Services to HIV Positive Persons 2015-2017

  Thornton, A., Cary, L., Forster, D., Huaman Joo, M., Karki Maskey, M., Leedy, N., Murphy, B., Myint, T., Romanelli, F., Schaninger, T., Hoellein, A. & Mullen, N.

  Health Resources and Services Administration

  4/1/15 → 3/31/16

  Project: Research project

  • Patient 100%
  • Hospital 64%
  • Person 30%
  • Human Immunodeficiency Virus 20%
  • Outpatient 10%

• Role of RFT1 in Dolichol-linked Oligosaccharide Assembly in Human Fibroblasts

  Rush, J.

  4/1/15 → 3/31/17

  Project: Research project

  • Dolichol 100%
  • Oligosaccharide 95%
  • Synthesis 33%
  • Mannose 23%
  • Glycosylation 19%

• Cyclin-D1/CDK4 Complex in Hepatocyte Profliferation

  Fan, W. & Lane, A.

  Minneapolis Medical Research Foundation

  4/1/15 → 6/30/15

  Project: Research project

  • Glucose 100%
  • Lipid 80%
  • Glutamine 80%
  • Sample 80%
  • Extract 80%

• The Role of Sin1 in Colorectal Cancer Progression

  Yang, H., Lee, E. & Wang, C.

  National Cancer Institute

  4/1/15 → 9/30/17

  Project: Research project

  • Colon 100%
  • Programmed Cell Death 83%
  • Linsidomine 83%
  • Apoptosis 83%
  • Colon Tumor 44%

• Analysis of insulin concentrations

  Lawrence, L.

  Alltech Incorporated

  4/15/15 → 12/31/16

  Project: Research project

• Reaching Rural Veterans: Engaging Faith-Based Food Pantries in Serving Low-Income, Homeless, and At-Risk Veterans in Rural Areas

  Ashurst, K.

  Purdue University

  5/26/15 → 8/25/16

  Project: Research project

  • Food 100%
  • Service Industries 75%
  • Communities 75%
  • Project 50%
  • Homeless 50%

• Overcoming Resistance to Enzalutamide with first-in-field TGF-beta Inhibition

  Kyprianou, N.

  6/1/15 → 5/31/19

  Project: Research project

  • Mesenchymal-Epithelial Transition 100%
  • Transforming Growth Factor Beta 66%
  • Androgen Receptor 44%
  • TGF Beta Signaling 44%
  • Prostate Cancer 44%

• TTP488 in patients with mild Alzheimer's Disease

  Murphy, R., Bardach, S. & Jicha, G.

  inVentiv Health Clinical

  6/18/15 → 3/27/19

  Project: Research project

• Targeting Prostate Tumor Microenvironment by a Novel Quinazoline

  Kyprianou, N. & Cao, Z.

  7/1/15 → 6/30/17

  Project: Research project

  • Prostate Cancer 100%
  • Synapsin II 50%
  • Quinazoline 50%
  • Protein Binding 50%
  • Cancer Cell 50%

• Intestinal Phosphatidylcholine Exposure and Breast Cancer Risk

  Onono, F., Morris, A., O'Connor, K. & Charnigo, R.

  National Cancer Institute

  7/1/15 → 6/30/20

  Project: Research project

  • Breast Cancer 100%
  • Obesity 61%
  • Lysophosphatidic Acid 61%
  • Egg Lecithin 53%
  • Cancer Risk 53%

• Biomarker Discovery by Interrogating Lung Cancer Lipid Metabolome

  Fan, W., Al-Attar, A., Arnold, S., Lane, A. & Martin, J.

  KY Lung Cancer Research Fund

  7/1/15 → 6/30/20

  Project: Research project

  • Lipid 100%
  • Lipid Profile 30%
  • Screening 23%
  • Species 15%
  • Smoking 15%

• PostDoctoral Fellowship for Reynolds: Perinatal tobacco exposure and mechanisms of offspring obesity and insulin resistance

  Pearson, K. & Reynolds, L.

  American Heart Association Great Rivers Affiliate

  7/1/15 → 6/30/17

  Project: Research project

  • Smoke 100%
  • Child 75%
  • Obesity 62%
  • Tobacco Smoke 50%
  • Nicotine 37%

• A phase 2a multi-center study of 18F-FDG PET, safety and tolerability of AZD0530 in mild Alzheimer#s disease

  Jicha, G., Bardach, S. & Murphy, R.

  University of Southern California

  7/1/15 → 5/31/18

  Project: Research project

  • Saracatinib 100%
  • Therapeutic Procedure 66%
  • Placebo 44%
  • Analysis 22%
  • Fluorodeoxyglucose F 18 22%

• Center for Innovation in Education - Continuation

  Wilhoit, H. & Pittenger, L.

  7/13/15 → 11/30/19

  Project: Research project

  • State 100%
  • Education 37%
  • Counselling 25%
  • Theory of Change 25%
  • Evidence 25%

• SBIR: System for Automated Noninvasive Monitoring of Mouse Sleep and Behavior

  Sunderam, S.

  Signal Solutions LLC

  8/1/15 → 4/30/18

  Project: Research project

• A Novel Mechanism for ART-Associated Dyslipidemia and Atherosclerosis

  Zhou, C., Daugherty, A., Greenberg, R., Kern, P., Morris, A., Temel, R. & Charnigo, R.

  National Heart Lung and Blood Institute

  8/1/15 → 7/31/19

  Project: Research project

  • Pregnane X Receptor 100%
  • Drug 76%
  • Atherosclerosis 61%
  • Dyslipidemia 46%
  • Hyperlipidemia 30%

• Acute effects of a pre-workout supplement on total upper and lower body resistance training volume and the subsequent strength, power, and anaerobic endurance performance

  Bergstrom, H., Clasey, J. & Wallace, B.

  MusclePharm Corporation

  8/1/15 → 3/23/16

  Project: Research project

• Saxagliptin to prevent coronary artery stiffness with HFpEF

  Fleenor, B.

  8/4/15 → 7/30/16

  Project: Research project

• The effect of FASN inhibition in human CRC

  Zaytseva, Y.

  3V Biosciences Incorporated

  8/9/15 → 12/31/16

  Project: Research project

• Telmisartan Plus Exercise to Improve Functioning in PAD: The TELEX Trial

  Peterson, C.

  8/17/15 → 4/30/17

  Project: Research project

  • Biological Product 100%
  • Inpatient 66%
  • Fiber 33%
  • Telmisartan 33%
  • Tenidap 33%

• Telmisartan Plus Exercise to Improve Functioning in PAD: The TELEX Trial

  Peterson, C.

  8/17/15 → 4/30/16

  Project: Research project

  • Biological Product 100%
  • Inpatient 66%
  • Fiber 33%
  • Telmisartan 33%
  • Tenidap 33%

• Telmisartan Plus Exercise to Improve Functioning in PAD: The TELEX Trial

  Peterson, C.

  8/17/15 → 6/30/19

  Project: Research project

  • Biological Product 100%
  • Inpatient 66%
  • Fiber 33%
  • Telmisartan 33%
  • Tenidap 33%

• Telmisartan Plus Exercise to Improve Functioning in PAD: The TELEX Trial

  Peterson, C.

  8/17/15 → 4/30/19

  Project: Research project

  • Biological Product 100%
  • Inpatient 66%
  • Fiber 33%
  • Telmisartan 33%
  • Tenidap 33%

• Telmisartan Plus Exercise to Improve Functioning in PAD: The TELEX Trial

  Peterson, C.

  8/17/15 → 4/30/18

  Project: Research project

  • Biological Product 100%
  • Inpatient 66%
  • Fiber 33%
  • Telmisartan 33%
  • Tenidap 33%

• Therapeutic Effects of Intranasally-Administered insulin (INI) in Adults with Amnestic Mild Cognitive Impairment (aMCI) or Mild Alzheimers Disease (AD)

  Jicha, G. & Murphy, R.

  University of Southern California

  8/21/15 → 6/30/17

  Project: Research project

  • Mild Cognitive Impairment 100%
  • Insulin 100%
  • Alzheimer Disease 100%
  • Biological Marker 50%
  • Therapy Effect 50%

• DPP in Hispanic and Non-Hispanic Women with a History of GDM

  Ashford, K. & Hieronymus, L.

  KY Department for Public Health

  9/1/15 → 6/30/16

  Project: Research project

  • Woman 100%
  • Diabetes Mellitus 62%
  • Hispanic 50%
  • Diabetes Prevention 37%
  • Impaired Glucose Tolerance 25%

• sEcad as a Novel Target and Therapy for IGF-1R Expressing Tumors

  Brouxhon, S., Weiss, H. & Samayoa, L.

  National Cancer Institute

  9/1/15 → 6/30/20

  Project: Research project

  • Somatomedin C Receptor 100%
  • Insulin-Like Growth Factor 1 Receptor 100%
  • Breast Cancer 42%
  • Mammalian Target of Rapamycin 42%
  • Antibody 28%

• Energy metabolism in platelets during thrombus formation

  Wang, Q. & Whiteheart, S.

  9/1/15 → 12/31/16

  Project: Research project

• Living Up to Her Potential: Increasing Dairy Cow Productivity and Welfare Using an Improved Understanding of Sleep

  Bewley, J., Donohue, K. & O'Hara, B.

  Ohio State University

  9/1/15 → 8/31/17

  Project: Research project

  • Research 100%
  • Animals 74%
  • Dairies 50%
  • Dairy Cows 50%
  • Environment 25%

• Cold Induced Changed in Human Subcutaneous White Adipose

  Kern, P., Bennett, T., Dupont-Versteegden, E., Finlin, B., Morris, A., Sullivan, P. & Westgate, P.

  National Institute Diabetes & Digestive & Kidney

  9/21/15 → 7/31/20

  Project: Research project

  • Adipose Tissue 100%
  • White Adipose Tissue 63%
  • Hypothesis 45%
  • Season 27%
  • Investigation 27%

• Inflammation and Renin-Angiotensin System Dysfunction as risk factors for AD

  Norris, C.

  Emory University

  9/30/15 → 6/30/16

  Project: Research project

  • Angiotensin 100%
  • Hypertension 66%
  • Renin 66%
  • Blood Brain Barrier 66%
  • Fat 66%

• Role of Oligomerized Amylin in Vascular Injury and Alzheimer's Disease

  Despa, F. & Nelson, P.

  Alzheimers Association

  10/1/15 → 3/31/19

  Project: Research project

  • Amylin 100%
  • Brain 36%
  • Diabetes 31%
  • Alzheimer's Disease 21%
  • Brain Blood Vessel 21%

• Do Horses With Equine Metabolic Syndrome (EMS) Have Reduced Immune Responses to Vaccination?

  Adams, A. & Horohov, D.

  American Quarter Horse Foundation

  10/1/15 → 9/30/16

  Project: Research project

  • Equine Metabolic Syndrome 100%
  • Horse 100%
  • Insulin 15%
  • Laminitis 15%
  • Mouse 7%

• A Phase 3, Randomized, Open-Label, Assessor-Blind, Non-Inferiority, Active-Comparator Study Evaluating the Efficacy and Safety of Liprotamase in Subjects with Cystic Fibrosis-Related Exocrine Pancreatic Insufficiency

  Danov, Z.

  Rho Incorporated

  10/28/15 → 9/30/17

  Project: Research project

• Specialty Crop: Plate It Up! Kentucky Proud Recipe Development and Evaluation for Consumers and Producers: Healthy Meals that Serve One or Two

  Stephenson, T. & Vail, A.

  KY Department of Agriculture

  12/1/15 → 9/30/18

  Project: Research project

  • Specialty Crops 100%
  • Recipes 75%
  • Adults 50%
  • Children 50%
  • Lifestyle 25%