Diabetes & Obesity Research Priority Area

Grants and Contracts

Grants and Contracts per year 1996 2013 2014 2015 2016 2017 2018 2019 2025

• 46 Active
• 389 Finished

Grants and Contracts per year

Search results

• Finished

  Resource Center for Stable Isotope-Resolved Metabolomics

  Higashi, R., Fan, W., Lane, A. & Moseley, H.

  National Institute Diabetes & Digestive & Kidney

  9/11/13 → 2/28/21

  Project: Research project

  • Metabolomics 100%
  • Motivation 36%
  • Sample 36%
  • Processing 27%
  • Stable Isotope 18%

• SBIR Phase II: Selection-Driven Plant Metabolites for Treatment of CNS Diseases

  Gerhardt, G.

  Naprogenix

  9/10/13 → 6/30/16

  Project: Research project

• Daily Rhythms and Health: Obesity and Related Disorders

  Pendergast, J.

  National Institute Diabetes & Digestive & Kidney

  9/6/13 → 6/30/16

  Project: Research project

  • Obesity 100%
  • Physiology 100%
  • Liver 100%
  • Behavior 75%
  • Human Nutrition 75%

• Don't Lose Sight of the Importance of Eye Exams-Using Telehealth in Primary Care Centers to Extend Access to Diabetic Retinopathy (DR) Screening

  Sprang, R., Sprang, R. & Higgins, E.

  Health Resources and Services Administration

  9/1/13 → 8/31/15

  Project: Research project

  • Patient 100%
  • Diabetes 84%
  • Diabetic Retinopathy 53%
  • Primary Health Care 53%
  • Screening 46%

• Telehealth Network Grant Program

  Sprang, R., Sprang, R. & Higgins, E.

  Health Resources and Services Administration

  9/1/13 → 2/28/17

  Project: Research project

  • Patient 100%
  • Diabetes 84%
  • Health 46%
  • Primary Health Care 46%
  • Screening 38%

• Don't Lose Sight of the Importance of Eye Exams-Using Telehealth in Primary Care Centers to Extend Access to Diabetic Retinopathy (DR) Screening

  Sprang, R., Sprang, R. & Higgins, E.

  Health Resources and Services Administration

  9/1/13 → 9/1/14

  Project: Research project

  • Patient 100%
  • Diabetes 84%
  • Diabetic Retinopathy 53%
  • Primary Health Care 53%
  • Screening 46%

• Hyperamylinemia in Diabetic Heart Disease: Mechanisms, Responses, and Prevention

  Despa, F., Cassis, L., Daugherty, A., Despa, S., Frolov, A. & Liu, M.

  National Heart Lung and Blood Institute

  8/23/13 → 7/31/16

  Project: Research project

  • Amylin 100%
  • Heart 60%
  • Oligomer 34%
  • Rat 34%
  • Calcium Ion 15%

• Hyperamylinemia in Diabetic Heart Disease: Mechanisms, Responses, and Prevention

  Despa, F., Cassis, L., Daugherty, A., Despa, S., Frolov, A. & Liu, M.

  National Heart Lung and Blood Institute

  8/23/13 → 7/31/18

  Project: Research project

  • Amylin 100%
  • Heart 60%
  • Oligomer 34%
  • Rat 34%
  • Calcium Ion 15%

• Circadian rhythms and melatonin signaling in the aging gastrointestinal system

  Cassone, V.

  National Institute on Aging

  8/15/13 → 5/31/18

  Project: Research project

  • Melatonin 100%
  • Aging 83%
  • Circadian Rhythm 66%
  • Nested Gene 66%
  • Gene 66%

• Circadian rhythms and melatonin signaling in the aging gastrointestinal system

  Cassone, V.

  National Institute on Aging

  8/15/13 → 5/31/16

  Project: Research project

  • Melatonin 100%
  • Aging 83%
  • Circadian Rhythm 66%
  • Nested Gene 66%
  • Gene 66%

• Adipocyte PRR Contributes to Obesity Induced Hypertension and Insulin Resistance

  Yiannikouris, F.

  7/1/13 → 12/31/17

  Project: Research project

  • Adipocyte 100%
  • Obesity 90%
  • Angiotensin II 72%
  • Insulin Resistance 72%
  • Adipose Tissue 63%

• Adipocyte PRR contributes to obesity induced hypertension and insulin resistance.

  Yiannikouris, F.

  7/1/13 → 6/30/15

  Project: Research project

  • Adipocyte 100%
  • Obesity 90%
  • Angiotensin II 72%
  • Insulin Resistance 72%
  • Adipose Tissue 63%

• Adipocyte PRR contributes to obesity induced hypertension and insulin resistance.

  Yiannikouris, F.

  7/1/13 → 6/30/16

  Project: Research project

  • Adipocyte 100%
  • Obesity 90%
  • Angiotensin II 72%
  • Insulin Resistance 72%
  • Adipose Tissue 63%

• Role of oligomeric amylin in impairing cardiac energy substrate metabolism

  Despa, F.

  American Heart Association

  7/1/13 → 11/30/15

  Project: Research project

  • Amylin 100%
  • Heart 50%
  • Rat 31%
  • Sarcolemma 25%
  • CD36 18%

• Ketone Body Administration to Treat Spinal Cord Injury

  Patel, S. & Rabchevsky, A.

  Craig H. Neilsen Foundation

  7/1/13 → 6/30/16

  Project: Research project

  • Spinal Cord Injury 100%
  • Levacecarnine 60%
  • Neuroprotection 40%
  • Mitochondrion 40%
  • Ketone Bodies 40%

• Appalachians Together Restoring the Eating Environment (APPAL-TREE)

  Swanson, M., Bush, H., Gustafson, A., Mullins, J., Schoenberg, N., Davis, A. & Fardo, D.

  National Institute on Minority Health and Health Disparities

  5/1/13 → 4/30/17

  Project: Research project

  • Communities 100%
  • Health 45%
  • Resident 36%
  • Research 36%
  • Obesity 36%

• NRSA Fellowship for Griggs: Methylglyoxal and TRPA1 contribution to neuropathic pain in type 2 diabetes

  Taylor, B. & Griggs, R.

  4/1/13 → 9/30/15

  Project: Research project

  • Pain 100%
  • Maturity Onset Diabetes of the Young 80%
  • Hypersensitivity 80%
  • Diabetes 80%
  • Glucose 60%

• CAREER: Glucan phosphatases: a key to designer starches and plant energy storage

  Gentry, M.

  3/15/13 → 2/28/19

  Project: Research project

  • Starch 100%
  • Glucan 76%
  • Phosphatase 61%
  • Metabolic Pathway 14%
  • Phosphorylation 14%

• Therapeutic Effect of Intranasal Insulin on Cognition, Function, and AD Biomarker

  Jicha, G. & Murphy, R.

  University of California San Diego Health

  3/1/13 → 4/30/16

  Project: Research project

  • Insulin 100%
  • Cognition 100%
  • Mild Cognitive Impairment 50%
  • Entorhinal Cortex 50%

• University of Kentucky Pilot and Feasibility Research Program

  Kern, P.

  Washington University in St. Louis

  2/23/13 → 11/30/22

  Project: Research project

  • Kentucky 100%
  • Universities 100%
  • Investigator 75%
  • St. Louis 50%
  • Diabetes 50%

• EMPOWR: Efforts to maximize perinatal outcomes in women at risk

  Ashford, K. & Williams, C.

  Centers for Medicare and Medicaid Services

  2/15/13 → 9/27/17

  Project: Research project

  • Woman 100%
  • Exercise 41%
  • Arm 25%
  • Incidence 16%
  • Obesity 16%

• EMPOWR: Efforts to maximize perinatal outcomes in women at risk

  Ashford, K., Fallin-Bennett, K., O'Brien, J., Williams, C., Playforth, K. & Van Arsdall, P.

  Centers for Medicare and Medicaid Services

  2/15/13 → 9/27/16

  Project: Research project

  • Woman 100%
  • Exercise 41%
  • Arm 25%
  • Incidence 16%
  • Obesity 16%

• EMPOWR: Efforts to maximize perinatal outcomes in women at risk

  Ashford, K., O'Brien, J., Playforth, K., Van Arsdall, P. & Williams, C.

  Centers for Medicare and Medicaid Services

  2/15/13 → 4/30/15

  Project: Research project

  • Woman 100%
  • Exercise 41%
  • Arm 25%
  • Incidence 16%
  • Obesity 16%

• Effects of Anti-miR-33 on Atherosclerosis Regression and RCT in Nonhuman Primates

  Temel, R.

  National Heart Lung and Blood Institute

  2/1/13 → 11/30/18

  Project: Research project

  • Cholesterol 100%
  • Reverse Cholesterol Transport 62%
  • Antisense 62%
  • High-Density Lipoprotein 62%
  • Oligonucleotide 62%

• Cardiovascular Inflammation Reduction Trial (CIRT)

  Messerli, A. & Bailey, A.

  Brigham and Women’s Hospital

  2/1/13 → 12/9/19

  Project: Research project

• A Study to Evaluate the Efficacy and Safety of GFT505 Once Daily on Steatohepatitis in Patients with Non-Alcoholic Steatohepatitis (NASH)

  Angulo, P., Ashe, L., Bruns, R., Chamblin, L., Holbrook, K., Kaenzig, J., Nicholson, S., Rosenau, J., Ross, D., Shedlofsky, S., Townsend, J., Turner, S., Walton-Davis, K. & Shardelow, E.

  Premier Research International LLC

  1/25/13 → 4/30/15

  Project: Research project

• Role for RitGTPAses Signaling in Forebrain Neurogenesis Following Traumatic Brain Injury

  Andres, D. & Saatman, K.

  KY Spinal Cord and Head Injury Research Trust

  1/15/13 → 1/15/17

  Project: Research project

  • Neurogenesis 100%
  • Neuron 88%
  • Brain Injury 33%
  • In Vitro 33%
  • Nerve Cell Differentiation 22%

• A 6-month safety and benefit study of Inhaled Fluticasone Propionate/Salmeterol Combination versus Inhaled Fluticasone Propionate in the Treatment of 6200 Pediatric Subjects 4-11 years old with Persistent Asthma

  Miller, B.

  Parexel International Co

  12/24/12 → 6/30/14

  Project: Research project

• Pluristem - A Phase 2, Randomized, Double-Blind, Multicenter, Multinational, Placebo-Controlled, Parallel-Group Study to Evaluate the Safety and Efficacy of Intramuscular Injections of Allogeneic PLX-PAD Cells for the Treatment of Subjects with Intermitte

  Saha, S., Ferraris, V., Minion, D., Sorial, E. & Xenos, E.

  Pluristem Therapeutics Incorporated

  11/1/12 → 3/31/15

  Project: Research project

• Enteral Formula Tolerance In the Obese Critical Care Population

  Bernard, A.

  Nestle HealthCare Nutrition Incorporated

  10/1/12 → 9/30/14

  Project: Research project

• A Novel Anti Obesity Drug Combination as a Pharmacotherapy for Cocaine Dependence

  Rush, C., Hays, L., Lile, J., Rayapati, A., Stoops, W. & Glaser, P.

  National Institute on Drug Abuse

  9/15/12 → 6/30/18

  Project: Research project

  • Cocaine Dependence 100%
  • Bupropion 100%
  • Naltrexone 89%
  • Cocaine 50%
  • Cannabis 50%

• Insulin Resistance Intervention after Stroke (IRIS) Trial 2013-2014

  Pettigrew, L.

  9/1/12 → 8/31/14

  Project: Research project

  • Stroke 100%
  • Insulin 100%
  • Insulin Resistance 100%
  • Placebo 50%
  • Transient Ischemic Attack 50%

• Insulin resistance Intervention after Stroke (IRIS) Trial 2015

  Pettigrew, L.

  9/1/12 → 8/31/15

  Project: Research project

  • Insulin Resistance 100%

• Regulation of Mitochondrial Oxidative Metabolism by Lipin 1 2015-2016 Yr 4

  Ren, H. & Morris, A.

  7/1/12 → 2/29/16

  Project: Research project

  • Mitochondrion 100%
  • Aerobic Metabolism 62%
  • Lipid Composition 37%
  • Triglyceride 37%
  • Surface Property 37%

• Regulation of Mitochondrial Oxidative Metabolism by Lipin 1

  Ren, H.

  7/1/12 → 6/30/15

  Project: Research project

  • Mitochondrion 100%
  • Aerobic Metabolism 62%
  • Lipid Composition 37%
  • Triglyceride 37%
  • Surface Property 37%

• The Insulin/IGF Axis in Diabetic Osteopathy

  Fowlkes, J., Bunn, R. & Thrailkill, K.

  National Institute Diabetes & Digestive & Kidney

  5/23/12 → 3/31/20

  Project: Research project

  • Mouse 100%
  • Insulin Receptor 50%
  • Mitogen-Activated Protein Kinase 50%
  • Signal Transduction 50%
  • Osteoblast 50%

• Regulation of Blood Pressure Circadian Rhythm by Vascular Smooth Muscle BMAL1

  Gong, M., Guo, Z., Duncan, M. & Esser, K.

  National Heart Lung and Blood Institute

  5/15/12 → 4/30/18

  Project: Research project

  • Circadian Rhythm 100%
  • Blood Pressure 77%
  • Nested Gene 16%
  • Gene 16%
  • Tissue 11%

• Advancing Health Communication Research Through the KCHC-DCHC Conference Series

  Harrington, N. & Johnson, S.

  National Cancer Institute

  4/19/12 → 3/31/18

  Project: Research project

  • Health 100%
  • Interpersonal Communication 88%
  • Conferences 77%
  • Health Communication 72%
  • Communication 72%

• Advancing Health Communication Research Through the KCHC-DCHC Conference Series

  Harrington, N. & Johnson, S.

  National Cancer Institute

  4/19/12 → 12/31/15

  Project: Research project

  • Health 100%
  • Interpersonal Communication 88%
  • Conferences 77%
  • Health Communication 72%
  • Communication 72%

• Healthy Tomorrows Partnership for Children Program-2016

  Northrip, K. & Jensen, J.

  Health Resources and Services Administration

  3/1/12 → 4/30/17

  Project: Research project

  • Child 100%
  • Health 36%
  • Advocacy 36%
  • Child Health 27%
  • Program 18%

• Healthy Tomorrows-2015

  Northrip, K. & Jensen, J.

  Health Resources and Services Administration

  3/1/12 → 2/29/16

  Project: Research project

  • Child 100%
  • Health 44%
  • Advocacy 44%
  • Child Health 33%
  • Family 22%

• Nutrition Intervention to Reduce Symptoms in Patients with Advanced Heart Failure

  Lennie, T., Biddle, M., Bruckner, G., El-Mallakh, P., Moser, D., Rayens, M. K., Thomas, D., Welsh, J. & Bailey, A.

  National Institute of Nursing Research

  9/27/11 → 7/31/16

  Project: Research project

  • Heart Failure 100%
  • Inpatient 100%
  • Symptom 50%
  • Patient 50%
  • Quality of Life 50%

• The Role of Adipose Tissue in Age-dependent Sensitivity to Critical Illiness

  Saito, H., Evers, B. M., Starr, M. & Stromberg, A.

  National Institute on Aging

  8/1/11 → 5/31/17

  Project: Research project

  • Adipose Tissue 100%
  • Critical Illness 87%
  • Age 62%
  • Aging 50%
  • Systemic Inflammatory Response Syndrome 50%

• Ceramide and acute phase protein elevation during aging

  Nikolova-Karakashian, M.

  National Institute on Aging

  8/1/11 → 8/31/17

  Project: Research project

  • Aging 100%
  • Insulin 60%
  • Ceramide 60%
  • IGFBP1 60%
  • Biological Activity 40%

• Preclinical evaluation of IGF1 therapy for traumatic brain injury

  Saatman, K., Chen, L. & Kizhakke Madathil, S.

  National Institute of Neurological Disorders & Stroke

  7/15/11 → 6/30/17

  Project: Research project

  • Traumatic Brain Injury 100%
  • Neurogenesis 50%
  • Growth Factor 50%
  • Insulin 50%
  • Angiogenesis 50%

• Maternal Exercise Protects Offspring from Obesity and Insulin Resistance

  Pearson, K.

  National Institute Diabetes & Digestive & Kidney

  1/1/11 → 12/31/16

  Project: Research project

  • Child 100%
  • Progeny 50%
  • Exercise 28%
  • Obesity 21%
  • Pregnancy 17%

• Rel B Mediated-Redox Regulation of Radiation Therapy

  St Clair, D., Shelton, B., St Clair, W., Strup, S. & Crispen, P.

  National Cancer Institute

  1/1/11 → 12/31/16

  Project: Research project

  • Prostate Cancer 100%
  • Interleukin 8 57%
  • Radiation Therapy 42%
  • Androgen 42%
  • Cancer Cell 28%

• LAPTOP-HF "Left Atrial Pressure Monitoring to Optimize Heart Failure Therapy Study

  Gurley, J.

  St Jude Medical Incorporated

  11/15/10 → 3/31/16

  Project: Research project

• Appalachia Community Cancer Network

  Dignan, M., Schoenberg, N., Shelton, B., Slone, M. & Webber, K.

  National Cancer Institute

  9/1/10 → 2/28/18

  Project: Research project

  • Universities 100%
  • Communities 87%
  • Cancer 75%
  • Program 62%
  • State 50%

• Vascular Metabolic Memory in Type II Diabetes

  Sherrow, J., Karounos, D. & Ratliff, S.

  Carl T Hayden Medical Research Foundation

  7/1/10 → 3/31/16

  Project: Research project

  • Maturity Onset Diabetes of the Young 100%
  • Memory 100%
  • Patient 50%
  • X-Ray Computed Tomography 50%
  • Abdominal Aorta 50%