Diabetes & Obesity Research Priority Area

Grants and Contracts

Grants and Contracts per year 1996 2013 2014 2015 2016 2017 2018 2019 2025

• 46 Active
• 389 Finished

Grants and Contracts per year

Search results

• sEcad as a Novel Target and Therapy for IGF-1R Expressing Tumors

  Brouxhon, S., Weiss, H. & Samayoa, L.

  National Cancer Institute

  9/1/15 → 6/30/20

  Project: Research project

  • Somatomedin C Receptor 100%
  • Insulin-Like Growth Factor 1 Receptor 100%
  • Breast Cancer 42%
  • Mammalian Target of Rapamycin 42%
  • Antibody 28%

• Selective Monoamine Release as a Treatment for Cocaine Use Disorders

  Stoops, W., Hays, L., Lile, J., Rayapati, A., Rush, C. & Glaser, P.

  National Institute on Drug Abuse

  9/1/14 → 5/31/19

  Project: Research project

  • Cocaine 100%
  • Cannabis 85%
  • Phendimetrazine 50%
  • Monoamine 42%
  • Cocaine Dependence 35%

• Serious Mental Illness

  Sheppard-Jones, K. & Eisenbaum, E.

  Administration for Community Living

  9/1/18 → 8/31/19

  Project: Research project

  • Intellectual and Developmental Disabilities 100%
  • Diseases 88%
  • Mental Illness 77%
  • Family 33%
  • Health Care Personnel 22%

• SLC9A1 and Neurodegenerative Disease

  Murphy, M. & Bachstetter, A.

  National Institute on Aging

  4/1/19 → 1/31/22

  Project: Research project

  • Pathology 100%
  • Tau 88%
  • Degenerative Disease 66%
  • Neurodegenerative Disorder 66%
  • Cerebrovascular Disease 44%

• Smart Shopping - Adolescent Intervention to Improve Food Shopping Practices Whre You Live and Learn

  Gustafson, A., Bush, H., Mullins, J. & Vail, A.

  National Institute of Food and Agriculture

  2/15/16 → 2/14/21

  Project: Research project

  • Intervention 100%
  • Youth 66%
  • Food 66%
  • Food Product 66%
  • Project 50%

• SNAP-Ed 2018

  Hunter, J., Cotterill, D. & Vail, A.

  KY Department of Community Based Services

  7/1/18 → 6/30/19

  Project: Research project

  • Nutrition 100%
  • Project 80%
  • Physical Activity 60%
  • Human Nutrition 60%
  • Evaluation 40%

• SNAP-Ed 2019-2020

  Hunter, J. & Aull, M.

  KY Department of Community Based Services

  7/1/18 → 6/30/20

  Project: Research project

  • Human Nutrition 100%
  • Physical Activity 66%
  • Nutrition Education 66%
  • Foods 33%
  • Fields 33%

• Social Network Analysis and Social Support Intervention for Rural Dwelling Older Adults with T2DM

  Smalls, B., Borgatti, S., Moser, D., Pearce, K. & Schoenberg, N.

  National Institute Diabetes & Digestive & Kidney

  1/1/19 → 6/30/19

  Project: Research project

  • Type 2 Diabetes 100%
  • Social Support 44%
  • Older Adult 44%
  • Communities 38%
  • Adult 33%

• Specialty Crop: Plate It Up! Kentucky Proud Recipe Development and Evaluation for Consumers and Producers: Healthy Meals that Serve One or Two

  Stephenson, T. & Vail, A.

  KY Department of Agriculture

  12/1/15 → 9/30/18

  Project: Research project

  • Specialty Crops 100%
  • Recipes 75%
  • Adults 50%
  • Children 50%
  • Lifestyle 25%

• Specialty Crop: Plate It Up! Kentucky Proud Recipe Development and Evaluation for Consumers and Producers Using Healthy Specialty Cooking Techniques with an Emphasis on Grilling

  Stephenson, T. & Vail, A.

  KY Department of Agriculture

  2/2/15 → 9/29/17

  Project: Research project

  • Specialty Crops 100%
  • Recipes 75%
  • Adults 25%
  • Lifestyle 25%
  • Children 25%

• Sphingolipids and Diabetes

  Ozcan, S.

  American Heart Association Great Rivers Affiliate

  7/1/14 → 6/30/15

  Project: Research project

  • Sphingosine 1 Phosphate 100%
  • Sphingosine-1-Phosphate 100%
  • Glucose 90%
  • Sphingosine Kinase 72%
  • Insulin Release 54%

• Sphingolipids and Diabetes

  Ozcan, S.

  American Heart Association Great Rivers Affiliate

  7/1/14 → 6/30/17

  Project: Research project

  • Sphingosine 1 Phosphate 100%
  • Sphingosine-1-Phosphate 100%
  • Glucose 90%
  • Sphingosine Kinase 72%
  • Insulin Release 54%

• State Obesity Evaluation Project FY15

  Dignan, M.

  KY Department for Public Health

  7/1/14 → 6/30/15

  Project: Research project

  • Evaluation Study 100%
  • Obesity 60%
  • Prevention 40%
  • Heart Disease 20%
  • Diabetes Control 20%

• Stimulation of posttraumatic neurogenesis by IGF-1 overexpression

  Saatman, K., Sama, D. & Smith, B.

  KY Spinal Cord and Head Injury Research Trust

  1/15/15 → 12/31/20

  Project: Research project

  • Neuron 100%
  • Insulin-Like Growth Factor 1 91%
  • Traumatic Brain Injury 41%
  • Neurogenesis 41%
  • Cell Proliferation 16%

• STTR: Mitochondrial Uncoupling as a Therapeutic Target in Obesity

  Sullivan, P. & Pearson, K.

  Nano Mite Technologies LLC

  9/16/14 → 1/31/16

  Project: Research project

• Study on Transdermal Delivery of Human Insulin to Mice in a Cream-Based Delivery System

  COHEN, D.

  11/15/14 → 11/30/16

  Project: Research project

• Sugar Metabolism in Fatty Liver Disease

  Softic, S.

  NASPGHAN Foundation

  7/1/19 → 7/30/21

  Project: Research project

  • Carbohydrate 100%
  • Fat 66%
  • Obesity 60%
  • Fructose 53%
  • Metabolism 46%

• Targeting MicroRNA-33 To Reduce Intracranial Atherosclerosis and Other Neurovascular Hallmarks of Vascular Cognitive Impairment and Dementia

  Temel, R., Nelson, P., Wilcock, D. & Head, E.

  National Institute of Neurological Disorders & Stroke

  4/1/19 → 3/31/22

  Project: Research project

  • Atherosclerosis 100%
  • Macrophage 68%
  • Statin 42%
  • microRNA 42%
  • MicroRNA 42%

• Targeting Prostate Tumor Microenvironment by a Novel Quinazoline

  Kyprianou, N. & Cao, Z.

  7/1/15 → 6/30/17

  Project: Research project

  • Prostate Cancer 100%
  • Synapsin II 50%
  • Quinazoline 50%
  • Protein Binding 50%
  • Cancer Cell 50%

• Telehealth Network Grant Program

  Sprang, R., Sprang, R. & Higgins, E.

  Health Resources and Services Administration

  9/1/13 → 2/28/17

  Project: Research project

  • Patient 100%
  • Diabetes 84%
  • Health 46%
  • Primary Health Care 46%
  • Screening 38%

• Telmisartan Plus Exercise to Improve Functioning in PAD: The TELEX Trial

  Peterson, C.

  8/17/15 → 4/30/18

  Project: Research project

  • Biological Product 100%
  • Inpatient 66%
  • Fiber 33%
  • Telmisartan 33%
  • Tenidap 33%

• Telmisartan Plus Exercise to Improve Functioning in PAD: The TELEX Trial

  Peterson, C.

  8/17/15 → 6/30/19

  Project: Research project

  • Biological Product 100%
  • Inpatient 66%
  • Fiber 33%
  • Telmisartan 33%
  • Tenidap 33%

• Telmisartan Plus Exercise to Improve Functioning in PAD: The TELEX Trial

  Peterson, C.

  8/17/15 → 4/30/16

  Project: Research project

  • Biological Product 100%
  • Inpatient 66%
  • Fiber 33%
  • Telmisartan 33%
  • Tenidap 33%

• Telmisartan Plus Exercise to Improve Functioning in PAD: The TELEX Trial

  Peterson, C.

  8/17/15 → 4/30/17

  Project: Research project

  • Biological Product 100%
  • Inpatient 66%
  • Fiber 33%
  • Telmisartan 33%
  • Tenidap 33%

• Telmisartan Plus Exercise to Improve Functioning in PAD: The TELEX Trial

  Peterson, C.

  8/17/15 → 4/30/19

  Project: Research project

  • Biological Product 100%
  • Inpatient 66%
  • Fiber 33%
  • Telmisartan 33%
  • Tenidap 33%

• The Activation of Brown and Beige Fat and Role in Insulin Sensitivity

  Kern, P., Dupont-Versteegden, E., El Khouli, R., Finlin, B., Tannock, L. & Hardy, P.

  National Institute Diabetes & Digestive & Kidney

  9/15/16 → 8/31/21

  Project: Research project

  • Agonist 100%
  • Brown Adipose Tissue 75%
  • Adipose Tissue 50%
  • Serositis 37%
  • Therapeutic Procedure 37%

• The Alltech-UK Animal Nutrigenomics Alliance

  Matthews, J.

  Alltech Incorporated

  9/1/06 → 12/31/22

  Project: Research project

• The effect of FASN inhibition in human CRC

  Zaytseva, Y.

  3V Biosciences Incorporated

  8/9/15 → 12/31/16

  Project: Research project

• The Effects of Exercise on Satellite Cell Dynamics During Aging

  Peterson, C., McCarthy, J. & White, S.

  National Institute on Aging

  1/1/16 → 2/28/21

  Project: Research project

  • Satellite Cell 100%
  • Age 44%
  • Aging 38%
  • Exercise 38%
  • Dynamics 33%

• The Effects of Exercise on Satellite Cell Dynamics During Aging

  Peterson, C., McCarthy, J. & White, S.

  National Institute on Aging

  1/1/16 → 6/30/19

  Project: Research project

  • Satellite Cell 100%
  • Age 44%
  • Aging 38%
  • Exercise 38%
  • Dynamics 33%

• The Impacts of Vaping Regulations on Perceptions, Access, Prices, and Tobacco Use

  Courtemanche, C.

  Georgia State University

  6/1/18 → 3/31/19

  Project: Research project

  • Cigarettes 100%
  • Electronic Cigarette 84%
  • Smoking 57%
  • State 42%
  • Policy 42%

• The Impacts of Vaping Regulations on Perceptions, Access, Prices, and Tobacco Use

  Courtemanche, C.

  Georgia State University

  6/1/18 → 3/31/21

  Project: Research project

  • Cigarettes 100%
  • Simulation Mode 84%
  • Electronic Cigarette 84%
  • Smoking 57%
  • State 42%

• The Impacts of Vaping Regulations on Perceptions, Access, Prices, and Tobacco Use

  Courtemanche, C.

  Georgia State University

  6/1/18 → 3/31/20

  Project: Research project

  • Cigarettes 100%
  • Electronic Cigarette 84%
  • Smoking 57%
  • State 42%
  • Policy 42%

• The insulin/IGF axis in diabetic osteopathy

  Fowlkes, J., Bunn, R. & Thrailkill, K.

  National Institute Diabetes & Digestive & Kidney

  5/23/14 → 3/31/16

  Project: Research project

  • Insulin 100%
  • Somatomedin C 73%
  • Knock Out 53%
  • Osteoblast 46%
  • Insulin Receptor 46%

• The Insulin/IGF Axis in Diabetic Osteopathy

  Fowlkes, J., Bunn, R. & Thrailkill, K.

  National Institute Diabetes & Digestive & Kidney

  5/23/12 → 3/31/20

  Project: Research project

  • Mouse 100%
  • Insulin Receptor 50%
  • Mitogen-Activated Protein Kinase 50%
  • Signal Transduction 50%
  • Osteoblast 50%

• The Insulin/IGF-I Axis in Diabetic Osteopathy

  Fowlkes, J., Bunn, R. & Thrailkill, K.

  National Institute Diabetes & Digestive & Kidney

  5/23/14 → 3/31/18

  Project: Research project

  • Insulin 100%
  • Somatomedin C 80%
  • Knock Out 53%
  • Osteoblast 46%
  • Insulin Receptor 46%

• Therapeutic Effect of Intranasal Insulin on Cognition, Function, and AD Biomarker

  Jicha, G. & Murphy, R.

  University of California San Diego Health

  3/1/13 → 4/30/16

  Project: Research project

  • Insulin 100%
  • Cognition 100%
  • Mild Cognitive Impairment 50%
  • Entorhinal Cortex 50%

• Therapeutic Effects of Exercise in Adults with Amnestic Mild Cognitive Impairment EXERT

  Jicha, G., Bardach, S., Caban-Holt, A., Murphy, R. & Raslau, F.

  University of California San Diego Health

  3/1/16 → 12/31/21

  Project: Research project

  • Mild Cognitive Impairment 100%
  • Heart Rate 100%
  • Adult 100%
  • Blindness 50%
  • Brain Blood Flow 50%

• Therapeutic Effects of Intranasally-Administered insulin (INI) in Adults with Amnestic Mild Cognitive Impairment (aMCI) or Mild Alzheimers Disease (AD)

  Jicha, G. & Murphy, R.

  University of Southern California

  8/21/15 → 6/30/17

  Project: Research project

  • Mild Cognitive Impairment 100%
  • Insulin 100%
  • Alzheimer Disease 100%
  • Biological Marker 50%
  • Therapy Effect 50%

• Therapeutic Effects of Intranasally-Administered insulin (INI) in Adults with Amnestic Mild Cognitive Impairment (aMCI) or Mild Alzheimer's Disease (AD)

  Jicha, G., Caban-Holt, A., Murphy, R. & Smith, C.

  University of Southern California

  7/1/17 → 8/6/19

  Project: Research project

  • Insulin 100%
  • Mild Cognitive Impairment 27%
  • Placebo 18%
  • Brain 18%
  • Cognition 18%

• The Role of Adipose Tissue in Age-dependent Sensitivity to Critical Illiness

  Saito, H., Evers, B. M., Starr, M. & Stromberg, A.

  National Institute on Aging

  8/1/11 → 5/31/17

  Project: Research project

  • Adipose Tissue 100%
  • Critical Illness 87%
  • Age 62%
  • Aging 50%
  • Systemic Inflammatory Response Syndrome 50%

• The Role of Fatty Acid Synthase in Regulation of Cancer Cells Survival and Metastasis in Colorectal Cancer

  Zaytseva, Y., Fan, W., Goel, G., Lee, E., Morris, A. & Weiss, H.

  National Cancer Institute

  8/1/16 → 2/28/17

  Project: Research project

  • Fatty Acid Synthase 100%
  • Metastasis 80%
  • Colorectal Cancer 73%
  • Malignant Neoplasm 46%
  • Cancer Cell 40%

• The Role of Gamma Delta - T Cells in Age-Associated Adipose Tissue Inflammation

  Starr, M., COHEN, D. & Stromberg, A.

  National Institute on Aging

  9/1/19 → 8/31/21

  Project: Research project

  • Adipose Tissue 100%
  • Mouse 54%
  • T Cell Receptor 45%
  • Inflammation 45%
  • Interleukin-6 36%

• The role of hepatic insulin resistance on SR-BI dependant HDL cholesterol uptake and metabolism

  Graf, G., Charnigo, R., Galperin, E. & Van Der Westhuyzen, D.

  National Institute Diabetes & Digestive & Kidney

  9/20/13 → 8/31/18

  Project: Research project

  • Insulin Signaling 100%
  • Cholesterol 83%
  • Randomized Controlled Trial 66%
  • Insulin Resistance 66%
  • High Density Lipoprotein Cholesterol 50%

• The role of hepatic insulin resistance on SR-BI dependant HDL cholesterol uptake and metabolism

  Graf, G., Charnigo, R., Galperin, E. & Van Der Westhuyzen, D.

  National Institute Diabetes & Digestive & Kidney

  9/20/13 → 8/31/16

  Project: Research project

  • Insulin Signaling 100%
  • Cholesterol 83%
  • Randomized Controlled Trial 66%
  • Insulin Resistance 66%
  • High Density Lipoprotein Cholesterol 50%

• The Role of PHLPP in Colon Cancer

  Gao, T., Al-Attar, A., Evers, B. M., Fan, W., Weiss, H., Wen, Y. A. & Xiong, X.

  National Cancer Institute

  4/1/08 → 7/31/20

  Project: Research project

  • Protein Phosphatase 100%
  • Leucine-Rich Repeat 94%
  • Pleckstrin Homology Domain 94%
  • Lipogenesis 52%
  • Cancer Cell 26%

• The Role of Sin1 in Colorectal Cancer Progression

  Yang, H., Lee, E. & Wang, C.

  National Cancer Institute

  4/1/15 → 9/30/17

  Project: Research project

  • Colon 100%
  • Programmed Cell Death 83%
  • Linsidomine 83%
  • Apoptosis 83%
  • Colon Tumor 44%

• The T1D Exchange Type 1 Diabetes Network

  Thrailkill, K., Fowlkes, J., Kalaitzoglou, E. & Morales, A.

  Jaeb Center for Health Research Foundation Incorporated

  6/1/16 → 3/22/19

  Project: Research project

  • Parent 100%
  • Informed Consent 100%
  • Insulin Dependent Diabetes Mellitus 100%

• Thrombospondin 1 in obesity associated inflammation and insulin resistance

  Wang, S., Cassis, L., Van Der Westhuyzen, D. & Zhan, C.

  National Institute Diabetes & Digestive & Kidney

  8/20/14 → 5/31/21

  Project: Research project

  • Thrombospondin 1 100%
  • Obesity 91%
  • Serositis 83%
  • Insulin Resistance 75%
  • Inflammation 66%

• TMAO is a Biomarker of Dioxin-Like Pollutant Exposure and Cardiometabolic Disease

  Petriello, M., Charnigo, R., Morris, A. & Smyth, S.

  National Institute of Environmental Health Sciences

  8/15/18 → 9/14/19

  Project: Research project

  • Trimethylamine 100%
  • Trimethylamine N-Oxide 88%
  • Dioxin 77%
  • Oxide 77%
  • Pollutant 77%