Markey Cancer Center / Cancer Research Priority Initiative

Kinnate Biopharma Incorporated

1/9/23 → 11/30/23

Project: Research project

Pilot: Targeting De Novo and Salvage Nucleotide Synthesis with FASN/ATR Inhibition to Enhance Radiation Therapy Reponses

Rychahou, P., Weiss, H. & Zaytseva, Y.

National Institute of General Medical Sciences

1/1/23 → 12/31/23

Project: Research project

Pilot: Role Of Succinate In Regulating Cancer Cell Plasticity And Stemness

Xu, R.

National Institute of General Medical Sciences

1/1/23 → 12/31/23

Project: Research project

Markey STRONG Post-baccalaureate Program

O'Connor, K., Adegboyega, A., Awuah, S., Blackburn, J., Brainson, C., Gao, T. & Williams, L.

National Institute of General Medical Sciences

1/1/23 → 12/31/25

Project: Research project

Pilot: CDK9-RNF20-LSD1 Axis in Breast Cancer Metabolic Reprogramming

Wu, Y.

1/1/23 → 12/31/23

Project: Research project

Institutional Research Grant

O'Connor, K.

Bristol Myers Squibb Foundation Incorporated

1/1/23 → 12/31/25

Project: Research project

Exploring and Planning Dissemination of the Quality Implementation of Lung Cancer Screening (QUILS) # System from the Kentucky LEADS Collaborative

Knight, J. & Mullett, T.

1/1/23 → 6/30/24

Project: Research project

Gold Complexes that Regulate Metabolism and Microbiome to Accelerate Mucosal Healing in IBD

Barrett, T., Alam, M., Awuah, S., Chaiswing, L., Kapur, N., Sullivan, P. & Wang, C.

Crohns and Colitis Foundation of America

1/1/23 → 12/31/23

Project: Research project

Diversity in Cancer Research Supplement: University of Kentucky

O'Connor, K., Adegboyega, A., Awuah, S., Blackburn, J., Brainson, C., Gao, T., Hull, P., Lee, Y., Williams, L. & Hahn, E.

1/1/23 → 12/31/25

Project: Research project

Key-Opinion-Led Best Practices in Diagnosis and Management of Breast, Lung, and Ovarian Cancers

Mullett, T.

OncoLens

1/1/23 → 12/31/23

Project: Research project

Patterns of Care Study: Diagnosis Year 2022 (Breast Cancer and Colorectal Cancer)

Durbin, E. B.

12/23/22 → 12/22/23

Project: Research project

22-MULTI-51-IT-PMC (TIG-006): A Multicenter, Open-Label, Phase I/II Study of EOS884448 In Combination With Standard Of Care And/Or Investigational Therapies In Participants With Advanced Solid Tumors

Villano, J.

iTeos Belgium SA

12/20/22 → 11/2/24

Project: Research project

22-MULTI-55-FP-PMC (FPI-2059-101): A Phase 1 Study of [225AC]-FPI-2059 In Adult Participants with NTSR1-Expressing Advanced, Metastatic and/or Recurrent Solid Tumours

Kunos, C.

12/20/22 → 10/4/24

Project: Research project

22-MULTI-52-EP-PMC: A Modular, Open-label, Phase I/II Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Efficacy of EP0031 in Patients with Advanced RET-altered Malignancies

Merck Sharp & Dohme Corporation

Ellipses Pharma Limited

11/11/22 → 8/29/24

Project: Research project

22-GI-128-RBI-PMC: Phase 1b/3 Global, Randomized, Controlled, Open-Label Trial Comparing Treatment With Actinium Ac 225 Dotatate (RYZ101) to Standard of Care (SoC) Therapy In Subjects With Inoperable, Advanced, Somatostatin Receptor Expressing (SSTR+)

Anthony, L.

RayzeBio Incorporated

10/25/22 → 7/26/24

Project: Research project

22-NEURO-13-NL: METIS, Pivotal, Open-label, Randomized Study of Radiosurgery with or Without Tumor Treating Fields (TTFields) for 1-10 Brain Metastases from Non-small Cell Lung Cancer (NSCLC)

Villano, J.

Novocure GmbH

10/24/22 → 8/3/24

Project: Research project

22-GI-126-BE-PMC: BXQ-350.AG, A Phase 1b/2 Placebo Controlled, Double Blinded Study on the Efficacy and Safety of BXQ-350 in Combination with mFOLFOX7 and Bevacizumab in Newly Diagnosed Metastatic Colorectal Carcinoma

Patel, R.

Clinical Trial Services

10/18/22 → 6/7/24

Project: Research project

MCC-22-GU-80: Phase II Study of Pembrolizumab in Combination with Radiation with or without Olaparib in Localized High-risk Prostate Cancer

Myint, Z.

10/12/22 → 9/18/24

Project: Research project

Platelet Metabolism in Diabetes Mellitus

Wang, Q., Fraser, J., Roberts, J., Wang, C., Whiteheart, S., Gentry, M. & Tannock, L.

National Heart Lung and Blood Institute

9/20/22 → 6/30/26

Project: Research project

22-MULTI-49-OM-PMC: OM-GRPR1-02, A Phase 1 Open-Label Dose Escalation and Expansion Study to Determine the Safety, Tolerability, Dosimetry, and Preliminary Efficacy of ???Pb-DOTAM-GRPR1 in Adult Subjects With Recurrent or Metastatic GRPR-expressing Tumors

Kunos, C.

9/15/22 → 7/10/24

Project: Research project

EPScOR: Robust and Reliable Mathematical Models for Biomolecular Data via Differential Geometry and Graph Theory

Nguyen, D. & Ellingson, S.

National Science Foundation

9/15/22 → 8/31/25

Project: Research project

Robust and Reliable Mathematical Models for Biomolecular Data via Differential Geometry and Graph Theory

Nguyen, D. & Ellingson, S.

National Science Foundation

9/15/22 → 8/31/25

Project: Research project

PRiMAL: Pragmatic Randomized Clinical Trial Comparing MTB Assisted Care to Usual Care

Kolesar, J., Arnold, S., Huang, B., Hull, P., McLouth, L., Weiss, H. & Westgate, P.

Eli Lilly and Company

9/2/22 → 11/7/24

Project: Research project

Pilot: Development and Pilot Testing of a Facebook HPV Vaccination Intervention for Young Black Adults

Adegboyega, A., Dignan, M., Francis, D., Hull, P. & Ickes, M.

9/1/22 → 12/15/23

Project: Research project

22-LUN-129-NP-PMC: CAAA601A42101, A Phase Ib Dose Finding Study Assessing Safety and Activity of [177Lu]Lu-DOTA-TATE in Newly Diagnosed Extensive Stage Small Cell Lung Cancer (ES-SCLC) in Combination with Carboplatin, Etoposide and Tislelizumab in Inducti

Hao, Z. & Chauhan, A.

Novartis (domestic)

8/23/22 → 6/12/24

Project: Research project

Alterations in DNA Damage following Major Surgery and Hyperthermic Intraperitoneal Chemotherapy

Kim, J., Gao, M., Goellner, E. & Weiss, H.

8/5/22 → 7/31/24

Project: Research project

22-MULTI-47-GS (IMMU-132-11): A Phase 2 Open-Label Study of Sacituzumab Govitecan (IMMU-132) in Subjects with Metastatic Solid Tumors

Gilead Sciences Inc

7/12/22 → 4/27/24

Project: Research project

FY24 Macrophage Derived Engineered Vesicles for Preventing Metastases in Pediatric Osteosarcoma

Kolesar, J., Badgett, J. & Richards, C.

Fred Hutchinson Cancer Center

7/1/22 → 6/30/24

Project: Research project

ReCAPSE: Recurrence using Claims and PROs for SEER Enhancement

Huang, B., Adams, V., Chen, J. & Durbin, E. B.

7/1/22 → 6/30/24

Project: Research project

FY24 Colon Cancer Screening Services C3599

Knight, J.

7/1/22 → 6/30/24

Project: Research project

Targeting Polo-Like Kinase 1 in Prostate Cancer to Enhance Therapeutic Efficacy

Li, Z., Allison, D., Liu, J., Lutz, C. & Wang, C.

7/1/22 → 6/30/27

Project: Research project

FY24 Colon Cancer Screening Services C3599 (State Funds)

Knight, J.

7/1/22 → 6/30/24

Project: Research project

FY24 Kentucky Cancer Program East Outreach - Colon Cancer Screening Services

Hull, P.

7/1/22 → 6/30/24

Project: Research project

FY24 Kentucky Cancer Program East Outreach - Colon Cancer Screening Services

Hull, P.

7/1/22 → 6/30/24

Project: Research project

FY24 Project Inherited Cancer Risk

D'Orazio, J., Allison, D., Badgett, J., Durbin, E. B., Harrington, A., Jeong, J. C., Kolesar, J., Overley, C., Shelman, N., Weiss, H., Zhang, S. & Shaw, A.

7/1/22 → 6/30/24

Project: Research project

Comprehensive Connected Cancer Care (C4)

Mullett, T., Chih, M., Faiola, A., McLouth, L., Shelton, B. & Hull, P.

Merck Company Fdn

7/1/22 → 6/30/27

Project: Research project

FY24 Accelerate

Durbin, E. B., Jeong, J. C., Villano, J. & Wang, C.

7/1/22 → 6/30/24

Project: Research project

FY24 Breast Cancer Screening and/or Cervical Cancer Community

Hull, P.

7/1/22 → 6/30/24

Project: Research project

Enhancing Patient Navigation at University of Kentucky Markey Cancer Center

Mullett, T., Chih, M. & Hull, P.

7/1/22 → 12/31/24

Project: Research project

FY24 Artesunate as Treatment for Childhood Acute Myeloid Leukemia

Kolesar, J., Badgett, J., Hill, K., Ji, H. & Yuan, L.

National Center for Chronic Disease Prevention & Healt

7/1/22 → 6/30/24

Project: Research project

Cancer Prevention and Control Programs for State Territorial and Tribal Organizations - NCCCP

Hull, P. & Knight, J.

6/30/22 → 6/29/27

Project: Research project

Cancer Prevention and Control Programs for State Territorial and Tribal Organizations - NPCR

Durbin, E. B., Huang, B. & Tucker, T.

National Center for Chronic Disease Prevention & Healt

6/30/22 → 6/29/27

Project: Research project

A Phase 1 First-in-Human, Drug-dose Escalation Study of RM-1995 Photoimmunotherapy, as Monotherapy or Combined with Pembrolizumab, in Patients With Advanced Cutaneous Squamous Cell Carcinoma or With Head and Neck Squamous Cell Carcinoma

Valentino, J.

Rakuten Medical Incorporated

6/14/22 → 2/21/24

Project: Research project

Development of Novel Treatments for Ovarian Cancer

Kolesar, J. & Awuah, S.

Markey Cancer Center Foundation

6/1/22 → 6/30/24

Project: Research project

A Phase 2, Open-Label, Single-Arm, Multicenter Study to Evaluate the Efficacy and Safety of Pemigatinib in Participants With Advanced Non-Small Cell Lung Cancer With an FGFR Alteration Who Progressed on Previous Therapy (FIGHT 210)

AVEO Pharmaceuticals Incorporated

Incyte Corporation

5/31/22 → 5/10/24

Project: Research project

A Phase 3, Randomized, Controlled, Multicenter, Open-Label Study to Compare Tivozanib in Combination with Nivolumab to Tivozanib Monotherapy in Subjects with Renal Cell Carcinoma Who Have Progressed Following One or Two Lines of Therapy

Myint, Z.

5/25/22 → 10/30/24

Project: Research project

Combating Melanoma Resistance by Targeting ABL1/2

Plattner, R., COHEN, D., Liu, J., Richards, D., Wang, C., Yan, D., Zhang, S., Kolesar, J. & Wang, P.