Markey Cancer Center / Cancer Research Priority Initiative

Vanderbilt University Medical Center

8/10/20 → 1/30/24

Project: Research project

Enhancing Cancer Care of Rural Dwellers through Telehealth and Engagement (ENCORE)

Hull, P.

8/1/20 → 7/31/24

Project: Research project

Translational Control in Cr(VI) Carcinogenesis

She, Q., Arnold, S., Lee, E., Wang, C. & Yang, C.

National Institute of Environmental Health Sciences

6/16/20 → 5/31/24

Project: Research project

Randomized Trial of a Social Media-Delivered Intervention Targeting Indoor Tanning Users

Stapleton, J. & Shelton, B.

6/1/20 → 5/31/24

Project: Research project

Mechanistic and Pharmacologic Studies of Selective Mithramycin Analogues Targeting EWS-FLI1 in Ewing Sarcoma

Tsodikov, O., Badgett, J., Rohr, J., Leggas, M., Wang, C. & Weiss, H.

6/1/20 → 5/31/25

Project: Research project

An Open-Label, Multi-Center, Rollover Study to Provide Continued Treatment Access for Participants Enrolled in Studies of BXQ-350

CTI Clinical Trial and Consulting Services

5/27/20 → 3/12/24

Project: Research project

A Phase 3, Multicenter, Randomized, Double-blind, Placebo-Controlled Study of AG-881 in Subjects With Residual or Recurrent Grade 2 Glioma With an IDH1 or IDH2 Mutation (AG881-C-004)

Servier Pharmaceuticals LLC

5/12/20 → 5/2/24

Project: Research project

A Phase 1 Study of SC-011 as a Single-Agent and in Combination with ABBV-181 in Subjects with Relapsed or Refractory Small Cell Lung Cancer

AbbVie Incorporated

5/6/20 → 10/30/24

Project: Research project

Mechanisms and Functions of Shoc2-Transduced Cellular Signals

Galperin, E. & Morris, A.

National Institute of Food and Agriculture

5/1/20 → 4/30/25

Project: Research project

Bridge Scholars Program - Bridging Disease Prevention Through Nutrition Focused Education In Community Clinics

Plasencia, J., Brewer, D., Ceballos Osorio, J., Grubbs, A., Miller, C. & Norman-Burgdolf, H.

5/1/20 → 4/30/25

Project: Research project

Long Term Follow-Up of Participants Exposed to GSK3377794 (NYESO-1c259 T), a Genetically Engineered NY-ESO-1 Specific T Cell Receptor (208750)

PPD Investigator Services LLC

4/30/20 → 1/11/24

Project: Research project

Children Eating Well (CHEW) Smartphone Application for WIC Families

Hull, P. & Faiola, A.

National Institute of Food and Agriculture

4/15/20 → 4/14/24

Project: Research project

Assessing the Anti-Cancer Activity of Artemesia Annua (Aa) Extracts

Kolesar, J. & Wu, J.

ArtemiLife Incorporated

4/14/20 → 12/5/23

Project: Research project

Noninvasive Noncontact High-Density Optical Imaging of Neonatal Intraventricular Hemorrhage

Yu, G., Abu Jawdeh, E., Bada, H., Chen, L., Chen, L., Cheng, Q., Huang, C., Powell, D., Huang, C. & Miller, B.

National Institute of Child Health and Human Develop

4/10/20 → 3/31/25

Project: Research project

Defining Genetic and Metabolic Requirements of Aggressive Breast Cancer (KY SOW)

Lane, A. & Fan, W.

University of Cincinnati

4/1/20 → 3/31/24

Project: Research project

An Open-Label, Randomised, Multicentre, Phase III Study of Irinotecan Liposome Injection, Oxaliplatin, 5-fluorouracil/Leucovorin Versus Nab-paclitaxel Plus Gemcitabine in Subjects Who Have Not Previously Received Chemotherapy for Metastatica

Patel, R.

Medpace Inc

3/24/20 → 1/11/24

Project: Research project

Perioperative Diffuse Optical Imaging of Tissue Blood Flow and Oxygenation for Optimization of Mastectomy Skin Flap Viability

Yu, G., Chen, L., Chen, L., Huang, C., Wong, L. & Huang, C.

National Institute of Biomedical Imaging & Bioengineer

3/15/20 → 11/30/24

Project: Research project

A Genomic Locus Associated with Radiation Resistance of Oral Cancer Cells

Izumi, T., Smith, M. & Smith, M.

3/3/20 → 11/30/23

Project: Research project

COBRE in Pharmaceutical Research and Innovation

Thorson, J., Adams, V., Alam, M., Awuah, S., Czuba, L., Dwoskin, L., Feola, D., Gensel, J., Grady, M., Graf, G., Jaramillo, A., Kapur, N., Mahmoud, K. A., Nikolajczyk, B., Ortinski, P., Pack, D., Park, J., Prisinzano, T., Rohr, J., She, Q., Stevenson, B., Tidgewell, K., Tiruvannamalai Annam, R., Van Lanen, S., Venditto, V., Zhan, C., Burgess, D., Daugherty, A., Garneau-Tsodikova, S., Glazer, E., Helmy, Y. A., Kolesar, J., Korotkov, K., Korotkova, N., Leggas, M., Richards, C., Sen, P., Shaffer, C., Sturgill, J., Sviripa, V., Watt, D. & Webb, N.

Gynecological Oncology Group Foundation Incorporated

3/1/20 → 1/31/25

Project: Research project

A Randomized Phase 3, Double-Blind Study of Chemotherapy With or Without Pembrolizumab Followed by Maintenance With Olaparib or Placebo for the First-Line Treatment of BRCA Non-Mutated Advanced Epithelial Ovarian Cancer (EOC)

Miller, R.

2/27/20 → 8/24/24

Project: Research project

PrE0905: Randomized Trial of Gilteritinib vs Midostaurin in FLT3 Mutated Acute Myeloid Leukemia (AML)

Qasrawi, A. & Hildebrandt, G.

Alpha Oncology Incorporated

2/27/20 → 10/30/24

Project: Research project

Radon on the RADAR

Hahn, E., Butler, K., Hoover, A., Rayens, M. K., Stanifer, S., Thaxton Wiggins, A. & Haneberg, W.

National Institute of Environmental Health Sciences

2/20/20 → 11/30/24

Project: Research project

Substudy 3: A Phase 2, Umbrella Study with Rolling Arms of Investigational Agents in Combination with Pembrolizumab in Patients with Advanced Non-small Cell Lung Cancer (NSCLC) Previously Treated with anti-PD-(L)1 Therapy

2/4/20 → 6/2/24

Project: Research project

Master: A Phase 2, Umbrella Study with Rolling Arms of Investigational Agents with either Pembrolizumab in Combination with Chemotherapy or with Pembrolizumab Alone in Patients with Advanced Non-small Cell Lung Cancer (NSCLC)

2/4/20 → 6/2/24

Project: Research project

Substudy 2: A Phase 2, Umbrella Study with Rolling Arms of Investigational Agents in Combination with Pembrolizumab in Treatment Naïve Patients with PD-L1 Positive Advanced Non-small Cell Lung Cancer (NSCLC)

2/4/20 → 6/2/24

Project: Research project

Substudy 1: A Phase 2, Umbrella Study with Rolling Arms of Investigational Agents with Pembrolizumab in Combination with Chemotherapy in Treatment-Naive Patients with Advanced Non-small Cell Lung Cancer (NSCLC)

Food and Drug Administration

2/4/20 → 6/2/24

Project: Research project

Scope: Cigar Reference Products Program

Shelton, B. & Shearer, A.

2/1/20 → 1/31/25

Project: Research project

Program Income: Cigar Reference Products Program

Chambers, O., Fisher, A., Fisher, C., Ji, H., McNees, C., Shelton, B. & Yuan, L.

Food and Drug Administration

2/1/20 → 1/31/25

Project: Research project

Cigar Reference Products Program

Chambers, O., Fisher, A., Fisher, C., Ji, H., McNees, C., Shelton, B. & Yuan, L.

Food and Drug Administration

2/1/20 → 1/31/25

Project: Research project

BMX-001 as a Therapeutic Agent for Treatment of Cancer Patients with Multiple Brain Metastases

Rakuten Medical Incorporated

BioMimetix JV LLC

1/23/20 → 5/31/24

Project: Research project

Institutional Research Grant

O'Connor, K.

American Cancer Society

1/1/20 → 12/31/23

Project: Research project

A Phase 3, Randomized, Double-Arm, Open-Label, Controlled Trial of ASP-1929 Photoimmunotherapy Versus Physician's Choice Standard of Care for the Treatment of Locoregional, Recurrent Head and Neck Squamous Cell Carcinoma

Valentino, J.

12/11/19 → 1/3/24

Project: Research project

New Activities of the Human DEK Oncogene

Lane, A.

Cincinnati Childrens Hospital Medical Center

12/1/19 → 11/30/24

Project: Research project

A Phase 3, Randomized, Placebo-Controlled Clinical Study to Evaluate the Safety and Efficacy of Stereotactic Body Radiotherapy (SBRT) with or without Pembrolizumab (MK-3475) in Participants with Medically Inoperable Stages I or IIA NSCLC

Gynecological Oncology Group Foundation Incorporated

11/27/19 → 11/7/24

Project: Research project

Comparison of Operative to Monitoring and Endocrine Therapy (COMET) Trial For Low Risk DCIS: A Phase III Prospective Randomized Trial

Marcinkowski, E.

11/25/19 → 2/14/24

Project: Research project

A Phase 3, Randomized, Double-Blind, Multicenter Study of Dostarlimab (TSR-042) Plus Carboplatin-Paclitaxel Versus Placebo Plus Carboplatin-Paclitaxel in Patients with Recurrent or Primary Advanced Endometrial Cancer (RUBY)

Miller, R.

11/15/19 → 1/16/24

Project: Research project

Hedgehog Signaling in Development and Metabolism

Jia, J., Wang, C., Vander Kooi, C. & Zhu, H.

9/1/19 → 8/31/24

Project: Research project

Hedgehog Signaling in the Brain Contributes to Alzheimer's Disease in a Drosophila Model

Jia, J.

9/1/19 → 8/31/24

Project: Research project

A Phase 1b Dose Escalation Study of Cabozantinib (XL184) Administered in Combination with Atezolizumab to Subjects with Locally Advanced or Metastatic Solid Tumors

Exelixis Inc.

8/13/19 → 1/2/24

Project: Research project

A Phase III, Randomized, Double-blind, Placebo-controlled, Multi-centre, International Study of Durvalumab or Durvalumab and Tremelimumab as Consolidation Treatment for Patients with Stage I/III Limited Disease Small-Cell Lung

AstraZeneca Pharmaceuticals AB

7/26/19 → 6/14/24

Project: Research project

Chemical Biology of the Control of Neddylation by DCN1

Guy, R. K.

7/1/19 → 6/30/24

Project: Research project

Targeting Epigenetic Heterogeneity to Improve Lung Cancer Immunotherapy Response

Brainson, C., Liu, J. & Wang, C.

7/1/19 → 6/30/24

Project: Research project

Methionine Metabolism and Lung Cancer Lineage Fate

Brainson, C., Absher, K., Liu, J. & Wang, C.

American Cancer Society

7/1/19 → 12/31/23

Project: Research project

MCC-18-MULTI-25-PMC (ESR-17-13115): Phase 2 Investigation of MEDI4736 (Durvalumab) and Tremelimumab Combination in Somatically Hypermutated Recurrent Solid Tumors

AstraZeneca Pharmaceuticals AB

5/7/19 → 11/2/24

Project: Research project

A Phase 2 Trial for Patients with Newly Diagnosed High Grade Glioma Treated with Concurrent Radiation Therapy, Temozolomide, and BMX-001

University of Pennsylvania

BioMimetix JV LLC

4/29/19 → 5/31/24

Project: Research project

Core 1: Improving Uptake of Cervical Cancer Prevention Services in Appalachia: Intervention Consortium Core

Dignan, M., Burris, J. & Vanderpool, R.

Ohio State University

4/11/19 → 3/31/24

Project: Research project

Using Nonclassical Estrogen Signaling to Prevent Melanoma

D'Orazio, J. & Jarrett, S.

4/1/19 → 3/31/24

Project: Research project

The Role of Multilevel Healthcare Access Dimensions in Ovarian Cancer Disparities

Huang, B. & Tucker, T.

Duke University

2/1/19 → 4/30/24

Project: Research project

Functional Analysis of Programmed Genome Rearrangement

Smith, J.