Markey Cancer Center / Cancer Research Priority Initiative

6/15/22 → 12/31/22

Project: Research project

Pilot: Lipid Metabolism Reprograming upon Spermine Synthase Inhibition in Colorectal Cancer

She, Q., Fan, W. & Wang, C.

6/15/22 → 12/31/22

Project: Research project

Pilot: Plk1 in Serine Metabolism of Prostate Cancer

Liu, X., Allison, D., Higashi, R., Moseley, H. & Wang, C.

6/15/22 → 12/31/22

Project: Research project

Pilot: Novel Role of the Metabolic Hormone Neurotensin on Liver Lipid Metabolism and Pathophysiology

Evers, B. M., Fan, W., Moseley, H. & Weiss, H.

Rakuten Medical Incorporated

6/15/22 → 12/31/22

Project: Research project

A Phase 1 First-in-Human, Drug-dose Escalation Study of RM-1995 Photoimmunotherapy, as Monotherapy or Combined with Pembrolizumab, in Patients With Advanced Cutaneous Squamous Cell Carcinoma or With Head and Neck Squamous Cell Carcinoma

Valentino, J.

6/14/22 → 2/21/24

Project: Research project

The VOYAGER Study: HPV16 E6 Antibody Detection as an Early Marker of Oropharyngeal Cancer

Kuhs, K.

6/1/22 → 6/30/23

Project: Research project

Tumor Microbiota-derived Signaling in Colon Carcinogenesis and Cancer Treatment

Alam, M., Evers, B. M., Gao, T. & Suzuki, Y.

Elsa U Pardee Foundation

6/1/22 → 5/31/23

Project: Research project

A Phase 2, Open-Label, Single-Arm, Multicenter Study to Evaluate the Efficacy and Safety of Pemigatinib in Participants With Advanced Non-Small Cell Lung Cancer With an FGFR Alteration Who Progressed on Previous Therapy (FIGHT 210)

Incyte Corporation

5/31/22 → 5/10/24

Project: Research project

Surveillance, Epidemiology, and End Results (SEER) Program

Durbin, E. B., Huang, B., Shelton, B., Tucker, T. & Ross, F.

Fred Hutchinson Cancer Center

5/1/22 → 4/30/23

Project: Research project

An Open-label, Randomized, Phase 3 Clinical Trial of IO102-IO103 in Combination With Pembrolizumab Versus Pembrolizumab Alone in Patients With Previously Untreated, Unresectable, or Metastatic (Advanced) Melanoma (IO102-IO103-013 / MK3475-D

Villano, PhD, J. & Wang, P.

IO Biotech ApS

4/5/22 → 2/19/24

Project: Research project

Targeting aberrant glycogen metabolism in CLN3 disease

Wang, Q. & Gentry, M.

4/1/22 → 3/31/23

Project: Research project

ReCAPSE: Recurrence using Claims and PROs for SEER Enhancement

Huang, B., Adams, V., Chen, J. & Durbin, E. B.

4/1/22 → 6/30/22

Project: Research project

Methods and Tools for Integrating Pathomics Data into Cancer Registries

Durbin, E. B., Bachert, S., Bocklage, T. & Qasem, S.

Research Foundation of State University of New York

4/1/22 → 3/31/24

Project: Research project

A Phase 3 Randomized Study Comparing Bortezomib, Lenalidomide and Dexamethasone (VRd) Followed by Ciltacabtagene Autoleucel, a Chimeric Antigen Receptor T Cell (CAR-T) Therapy Directed Against BCMA Versus Bortezomib, Lenalidomide, and D

Monohan, G.

Janssen Research and Development LLC

3/15/22 → 1/29/24

Project: Research project

Erythrocyte-Derived Particles for Near Infrared Phototherapy of Port Wine Stains

D'Orazio, J.

Regents of the University of California Riverside

3/1/22 → 2/28/24

Project: Research project

Phase Ib trial of gilteritinib in combination with mitoxantrone, cladribine, cytarabine and filgrastim (GM-CLAG) for relapsed/refractory FLT3-mutated acute myeloid leukemia

Qasrawi, A. & Hildebrandt, G.

Astellas Pharma Global Development Incorporated

1/17/22 → 10/30/23

Project: Research project

Racial Disparities in Financial Toxicity, Cost-Related Health Literacy, and HealthCare Transitions among Adolescent and Young Adult (AYA) Cancer Survivors in Kentucky

Edward, J.

1/1/22 → 12/31/22

Project: Research project

SUPPLEMENT: Diversity in Cancer Research Supplement: University of Kentucky

O'Connor, K., Awuah, S., Bocklage, T., Cavnar, M., Chambers, M., Gao, T., Gentry, M., Goellner, E., Kuhs, K., Miller, R., Wang, X. & Williams, L.

1/1/22 → 12/31/22

Project: Research project

ChemoRadiation And Tislelizumab for Esophageal/EGJ Cancer (CRATER)

Hao, Z.

BeiGene Switzerland GmbH

12/24/21 → 5/27/22

Project: Research project

A Randomized, Open-Label, Phase 3 Trial of Epcoritamab vs Investigator s Choice Chemotherapy in Relapsed/Refractory Diffuse Large B-cell Lymphoma

Iragavarapu, C. & Hildebrandt, G.

Genmab US Incorporated

12/15/21 → 7/31/24

Project: Research project

Phase II Clinical Trial Evaluating Cabozantinib and Pembrolizumab in Second-Line Therapy for Metastatic Pancreatic Adenocarcinoma

Kim, J., Fan, W., Gao, M., Higashi, R., Rueckert, J. & Qasem, S.

Exelixis Inc.

12/15/21 → 6/7/24

Project: Research project

A Randomized, Multi-Center, Open-Label, Active-Controlled Phase 3 Trial to Assess the Efficacy and Safety of Octreotide Subcutaneous Depot (CAM2029) versus Octreotide LAR or Lanreotide ATG in Patients with Gastroenteropancreatic

Anthony, L.

Fortrea Incorporated

12/2/21 → 8/21/24

Project: Research project

Developing a novel therapy for CLN3 disease-related neurological deficits

Wang, Q., Norris, C., O'Hara, B., Sunderam, S. & McLouth, C.

12/1/21 → 11/30/22

Project: Research project

A Phase 1b/2 Study to Evaluate the Efficacy and Safety of Pembrolizumab in Combination With Investigational Agents for the Treatment of Participants With PD-1/L1-refractory Extensive-Stage Small Cell Lung Cancer in Need of Second-Line

Merck Sharp & Dohme Corporation

11/16/21 → 9/13/24

Project: Research project

Phase 1 First-in-Human (FIH) Study of Leukocyte Immunoglobulin-Like Receptor B2 (LILRB2) Inhibitor Monoclonal Antibody (mAb) JTX-8064, as Monotherapy and in Combination with a Programmed Cell Death Receptor-1 (PD-1) In

Myint, Z. & Chauhan, A.

Jounce Therapeutics Incorporated

11/8/21 → 9/18/23

Project: Research project

A Phase 1/2 Dose Escalation and Dose Expansion Study of BA3021 Alone and In Combination With Nivolumab In Patients With Advanced Solid Tumors

Fortrea Incorporated

11/5/21 → 10/4/24

Project: Research project

A Phase 1/2a, Open-Label, Multicentre Study To Evaluate The Safety, Pharmacokinetics, And Preliminary Efficacy Of Subcutaneous Durvalumab In Patients With Non-Small Cell And Small Cell Lung Cancer -- SCope-D1

AstraZeneca Pharmaceuticals LP (domestic)

10/19/21 → 8/24/23

Project: Research project

Advancing Health Equity Through Clinical Trial Diversity

Williams, L.

10/1/21 → 9/30/23

Project: Research project

A Phase 2 Study of BA3011 Alone and in Combination With PD-1 Inhibitor in Adult Patients With Metastatic Non-small Cell Lung Cancer (NSCLC) Who Had Prior Disease Progression on a PD-1/L-1 Inhibitor

American Society of Clinical Oncology

Fortrea Incorporated

9/14/21 → 3/20/24

Project: Research project

ASCO-ACCC Pilot Project: Tool Pilot Study

Williams, L. & Ramlal, R.

9/7/21 → 3/31/22

Project: Research project

ASCO-ACCC Pilot Project: Training Pilot Study

Williams, L. & Ramlal, R.

American Society of Clinical Oncology

9/7/21 → 3/31/22

Project: Research project

Fellowship for Lyndsay Young: Aberrant Glycogen Modulates Metabolism in Ewing's Sarcoma

Gao, T., Evers, B. M. & Gentry, M.

9/1/21 → 8/31/22

Project: Research project

Fellowship for Lyndsay Young: Aberrant Glycogen Modulates Metabolism in Ewing's Sarcoma

Gao, T. & Evers, B. M.

9/1/21 → 1/3/23

Project: Research project

A Phase 3 Open-Label, Randomized Study of LOXO-305 versus Investigator's Choice of Idelalisib plus Rituximab or Bendamustine plus Rituximab in BTK Inhibitor Pretreated Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma

Munker, R.

IQVIA RDS Incorporated

8/31/21 → 4/24/23

Project: Research project

Allogeneic CRISPR-Cas9 Engineered T Cells (CTX110) in Subjects With Relapsed or Refractory B Cell Malignancies

Iragavarapu, C. & Hildebrandt, G.

CRISPR Therapeutics AG

8/10/21 → 10/19/22

Project: Research project

Targeting Cell Powerhouses -Mitochondria- to Enhance Radiation Treatment Outcomes

Chaiswing, L.

8/1/21 → 9/30/22

Project: Research project

Tampering with ERK1/2 Signals for Cancer Treatment

Galperin, E.

8/1/21 → 8/1/23

Project: Research project

Pilot: MR Imaging of Tumor Associated Macrophage Changes with Therapy

Chapelin, F. & O'Connor, K.

8/1/21 → 10/31/22

Project: Research project

The BURAN Study of Buparlisib (AN2025) In Combination With Paclitaxel Compared to Paclitaxel Alone, in Patients With Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma

National Institute Arthritis Musculoskeletal & Skin

Syneos Health LLC

7/20/21 → 4/19/23

Project: Research project

24th Annual Meeting of the PanAmerican Society for Pigment Cell Research: "Harnessing the Power of Scientific Discoveries in Pigment Cell Research"

D'Orazio, J.

7/10/21 → 6/30/22

Project: Research project

A Phase 1, Open-label Study of ASP9801, an Oncolytic Virus, Administered by Intratumoral Injection in Patients with Advanced/Metastatic Solid Tumors

Villano, PhD, J. & Chauhan, A.

Astellas Pharma Global Development Incorporated

7/5/21 → 7/13/24

Project: Research project

Statistical Methods for Cancer Progression Delineation and Subtype Identification

Wang, C., Arnold, S. & Liu, C.

7/1/21 → 6/30/24

Project: Research project

Summer Health Experience (SHE) in Oncology Program

Vanderford, N.

Boston Childrens Hospital

7/1/21 → 12/31/21

Project: Research project

Natural Language Processing Platform for Cancer Surveillance

Durbin, E. B., Jeong, J. C. & Kavuluru, R.

7/1/21 → 6/30/23

Project: Research project

Pilot: Post Transcriptional Control of Ribosomal Proteins in Hematopoietic Neoplasia

Garcia, E. & O'Connor, K.

7/1/21 → 6/30/22

Project: Research project

CCSG Pilot: Elucidating How a Truncating ATR Mutation Leads to Genomic Instability

D'Orazio, J., Evers, B. M., Shelton, B. & Zaytseva, Y.

7/1/21 → 6/30/23

Project: Research project

CCSG Supplement: Childhood Cancer Survivors

Evers, B. M., Borders, T., D'Orazio, J., Durbin, E. B., Stapleton, J. & Vanderford, N.