Markey Cancer Center / Cancer Research Priority Initiative

AstraZeneca Pharmaceuticals LP (domestic)

9/1/22 → 9/30/22

Project: Research project

22-MULTI-48-AZ-PMC: D9950C00001 A Phase 1 First-in-human Study to Evaluate the Safety, Pharmacokinetics, Pharmacodynamics and Efficacy of AZD8701 Administered Intravenously as Monotherapy and in Combination with Durvalumab (MEDI4736)

Arnold, S.

7/13/22 → 6/28/23

Project: Research project

FY23 Colon Cancer Screening Services C3599

Knight, J.

7/1/22 → 6/30/23

Project: Research project

CCSG Pilot: Targeting L-Tryptophan-5-Hydroxylase 1 (TPH1) in Small Cell Lung Cancer

Wei, Q., Chen, L. & Hao, Z.

7/1/22 → 6/30/23

Project: Research project

CCSG Pilot: Integrating AI-based Protein 3D Structure Prediction and In-silico Ligand Screening to Discover FDA approved Drugs Overcoming Therapy Resistance of Uncommon EGFR-mutant Lung Cancers

Ellingson, S., Brainson, C., Liu, X., Shao, Q. & Zinner, R.

7/1/22 → 6/30/23

Project: Research project

FY23 Kentucky Cancer Program East Outreach - Colon Cancer Screening Services

Hull, P.

7/1/22 → 6/30/23

Project: Research project

FY23 Breast Cancer Screening and/or Cervical Cancer Community

Hull, P.

7/1/22 → 6/30/23

Project: Research project

FY23 Kentucky Cancer Program East Outreach - Colon Cancer Screening Services

Hull, P.

7/1/22 → 6/30/23

Project: Research project

Summer Health Experience (SHE) in Oncology Program

Vanderford, N.

7/1/22 → 12/31/22

Project: Research project

FY23 Colon Cancer Screening Services C3599 (State Funds)

Knight, J.

7/1/22 → 6/30/23

Project: Research project

Comprehensive Connected Cancer Care (C4)

Mullett, T., Chih, M., Faiola, A., McLouth, L., Shelton, B. & Hull, P.

Merck Company Fdn

7/1/22 → 6/30/23

Project: Research project

FY23 Artesunate as Treatment for Childhood Acute Myeloid Leukemia

Kolesar, J., Badgett, J., Ellingson, S., Hill, K., Ji, H. & Yuan, L.

7/1/22 → 6/30/23

Project: Research project

FY23 Colon Cancer MSI MMR Study

Tucker, T. & Huang, B.

7/1/22 → 6/30/23

Project: Research project

FY23 Accelerate

Durbin, E. B., Jeong, J. C., Villano, J. & Wang, C.

7/1/22 → 6/30/23

Project: Research project

FY23 Germline and Environmental Factors Associated with Pediatric Brain and Central Nervous System Tumors in Kentucky

Durbin, E. B., Christian, J., Haynes, E. & Liu, J.

7/1/22 → 6/30/23

Project: Research project

FY23 Macrophage Derived Engineered Vesicles for Preventing Metastases in Pediatric Osteosarcoma

Kolesar, J., Badgett, J. & Richards, C.

7/1/22 → 6/30/23

Project: Research project

Pediatric Molecular Tumor Board C3358: FY 23

Villano, J., Badgett, J., Durbin, E. B., Kolesar, J., Lightner, D., Lukins, D., Mirza, F., Morgan, R. & Shelton, B.

Helmy, Y. A. & Messaoudi Powers, I.

7/1/22 → 6/30/23

Project: Research project

Evaluate the efficacy of probiotics on colonization and pathogenicity of Campylobacter jejuni

7/1/22 → 12/31/22

Project: Research project

FY23 Project Inherited Cancer Risk

D'Orazio, J., Allison, D., Badgett, J., Durbin, E. B., Harrington, A., Jeong, J. C., Kolesar, J., Overley, C., Shelman, N., Weiss, H., Zhang, S. & Shaw, A.

National Center for Chronic Disease Prevention & Healt

7/1/22 → 6/30/23

Project: Research project

Cancer Prevention and Control Programs for State Territorial and Tribal Organizations - CIN (carryover funds)

Tucker, T.

6/30/22 → 6/29/23

Project: Research project

Cancer Prevention and Control Programs for State Territorial and Tribal Organizations - NPCR (carryover funds)

Durbin, E. B., Huang, B. & Tucker, T.

National Center for Chronic Disease Prevention & Healt

6/30/22 → 6/29/23

Project: Research project

Cancer Prevention and Control Programs for State Territorial and Tribal Organizations - NCCCP (carryover funds)

Hull, P. & Knight, J.

National Center for Chronic Disease Prevention & Healt

6/30/22 → 6/29/23

Project: Research project

Supplement: Cancer Prevention and Control Programs for State Territorial and Tribal Organizations - NCCCP Supplement (carryover funds)

Hull, P. & Tucker, T.

National Center for Chronic Disease Prevention & Healt

6/30/22 → 6/29/23

Project: Research project

Pilot: Novel Role of the Metabolic Hormone Neurotensin on Liver Lipid Metabolism and Pathophysiology

Evers, B. M., Fan, W., Moseley, H. & Weiss, H.

6/15/22 → 12/31/22

Project: Research project

Pilot: Validation of Peripheral Blood Exosome Lipid Biomarkers in Lung Cancer and IBD

Barrett, T., Arnold, S., Higashi, R., Khosravi, M. & Wang, C.

6/15/22 → 12/31/22

Project: Research project

Pilot: Lipid Metabolism Reprograming upon Spermine Synthase Inhibition in Colorectal Cancer

She, Q., Fan, W. & Wang, C.

6/15/22 → 12/31/22

Project: Research project

Pilot: Plk1 in Serine Metabolism of Prostate Cancer

Liu, X., Allison, D., Higashi, R., Moseley, H. & Wang, C.

Markey Cancer Center Foundation

6/15/22 → 12/31/22

Project: Research project

Tumor Microbiota-derived Signaling in Colon Carcinogenesis and Cancer Treatment

Alam, M., Evers, B. M., Gao, T. & Suzuki, Y.

Elsa U Pardee Foundation

6/1/22 → 5/31/23

Project: Research project

The VOYAGER Study: HPV16 E6 Antibody Detection as an Early Marker of Oropharyngeal Cancer

Kuhs, K.

6/1/22 → 6/30/23

Project: Research project

Surveillance, Epidemiology, and End Results (SEER) Program

Durbin, E. B., Huang, B., Shelton, B., Tucker, T. & Ross, F.

Fred Hutchinson Cancer Center

5/1/22 → 4/30/23

Project: Research project

ReCAPSE: Recurrence using Claims and PROs for SEER Enhancement

Huang, B., Adams, V., Chen, J. & Durbin, E. B.

4/1/22 → 6/30/22

Project: Research project

Targeting aberrant glycogen metabolism in CLN3 disease

Wang, Q. & Gentry, M.

4/1/22 → 3/31/23

Project: Research project

Racial Disparities in Financial Toxicity, Cost-Related Health Literacy, and HealthCare Transitions among Adolescent and Young Adult (AYA) Cancer Survivors in Kentucky

Edward, J.

1/1/22 → 12/31/22

Project: Research project

SUPPLEMENT: Diversity in Cancer Research Supplement: University of Kentucky

O'Connor, K., Awuah, S., Bocklage, T., Cavnar, M., Chambers, M., Gao, T., Gentry, M., Goellner, E., Kuhs, K., Miller, R., Wang, X. & Williams, L.

Jounce Therapeutics Incorporated

1/1/22 → 12/31/22

Project: Research project

ChemoRadiation And Tislelizumab for Esophageal/EGJ Cancer (CRATER)

Hao, Z.

BeiGene Switzerland GmbH

12/24/21 → 5/27/22

Project: Research project

Developing a novel therapy for CLN3 disease-related neurological deficits

Wang, Q., Norris, C., O'Hara, B., Sunderam, S. & McLouth, C.

12/1/21 → 11/30/22

Project: Research project

Phase 1 First-in-Human (FIH) Study of Leukocyte Immunoglobulin-Like Receptor B2 (LILRB2) Inhibitor Monoclonal Antibody (mAb) JTX-8064, as Monotherapy and in Combination with a Programmed Cell Death Receptor-1 (PD-1) In

Myint, Z. & Chauhan, A.

11/8/21 → 9/18/23

Project: Research project

A Phase 1/2a, Open-Label, Multicentre Study To Evaluate The Safety, Pharmacokinetics, And Preliminary Efficacy Of Subcutaneous Durvalumab In Patients With Non-Small Cell And Small Cell Lung Cancer -- SCope-D1

Arnold, S.

AstraZeneca Pharmaceuticals LP (domestic)

10/19/21 → 8/24/23

Project: Research project

ASCO-ACCC Pilot Project: Tool Pilot Study

Williams, L. & Ramlal, R.

American Society of Clinical Oncology

9/7/21 → 3/31/22

Project: Research project

ASCO-ACCC Pilot Project: Training Pilot Study

Williams, L. & Ramlal, R.

American Society of Clinical Oncology

9/7/21 → 3/31/22

Project: Research project

Fellowship for Lyndsay Young: Aberrant Glycogen Modulates Metabolism in Ewing's Sarcoma

Gao, T., Evers, B. M. & Gentry, M.

9/1/21 → 8/31/22

Project: Research project

Fellowship for Lyndsay Young: Aberrant Glycogen Modulates Metabolism in Ewing's Sarcoma

Gao, T. & Evers, B. M.

Markey Cancer Center Foundation

9/1/21 → 1/3/23

Project: Research project

A Phase 3 Open-Label, Randomized Study of LOXO-305 versus Investigator's Choice of Idelalisib plus Rituximab or Bendamustine plus Rituximab in BTK Inhibitor Pretreated Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma

Munker, R.

IQVIA RDS Incorporated

8/31/21 → 4/24/23

Project: Research project

Allogeneic CRISPR-Cas9 Engineered T Cells (CTX110) in Subjects With Relapsed or Refractory B Cell Malignancies

Iragavarapu, C. & Hildebrandt, G.

CRISPR Therapeutics AG

8/10/21 → 10/19/22

Project: Research project

Targeting Cell Powerhouses -Mitochondria- to Enhance Radiation Treatment Outcomes

Chaiswing, L.

8/1/21 → 9/30/22

Project: Research project

Pilot: MR Imaging of Tumor Associated Macrophage Changes with Therapy

Chapelin, F. & O'Connor, K.