Microbiology, Immunology, and Molecular Genetics

73 Active
374 Finished

1 - 50 out of 447 results

Active
Mechanisms of Thrombosis in SARS CoV-2 Infection
Wood, J. (PI), Garvy, B. (CoI), Simmons, C. (CoI), Whiteheart, S. (CoI) & Wu, C. (CoI)
National Heart Lung and Blood Institute
1/15/25 → 11/30/28
Project: Research project
Mechanisms of Thrombosis in SARS CoV-2 Infection
Wood, J. (PI), Garvy, B. (CoI), Simmons, C. (CoI), Whiteheart, S. (CoI) & Wu, C. (CoI)
National Heart Lung and Blood Institute
1/15/25 → 11/30/28
Project: Research project
Encoding Immune-Modulation Within mRNA Vaccines Against the Model Flavivirus, West Nile Virus
Brien, J. (PI)
Merck Sharp & Dohme Corporation
12/17/24 → 12/16/26
Project: Research project
The Impact of Antiretroviral Therapy on Fetal Immune System Development in SIV-exposed Rhesus Macaques
Messaoudi Powers, I. (PI)
Oregon Health and Sciences University
9/20/24 → 6/30/27
Project: Research project
Renewal - Transcriptional and Non-Transcriptional Functions of IRF3 in ALD
Chattopadhyay, S. (PI)
Cleveland Clinic Lerner College of Medicine of Case Western Reserve University
9/1/24 → 6/30/29
Project: Research project
Supplemental Funds: SARS-CoV-2 Correlates of Protection in a Latino-origin Population
Brien, J. (PI) & Pinto, A. (CoI)
Universidad de Puerto Rico
9/1/24 → 5/31/25
Project: Research project
Role of Putative Cytotoxins in Chlamydia Infection
Fields, K. (PI)
National Institute of Allergy and Infectious Diseases
8/21/24 → 6/30/26
Project: Research project
Targeting Lung Fibrosis Using Epigenetic Therapy
Brainson, C. (PI), Allison, D. (CoI), Beswick, E. (CoI), Liu, J. (CoI), Sturgill, J. (CoI), Weiss, H. (CoI) & Waters, C. (Former CoI)
National Heart Lung and Blood Institute
8/15/24 → 7/31/28
Project: Research project
NRSA Fellowship For Madison Blanton: Uncovering The Functional And Mechanistic Dysregulation Of Monocytes After Abstinence And Post-Abstinence Drinking
Messaoudi Powers, I. (PI)
National Institute on Alcohol Abuse and Alcoholism
8/12/24 → 8/11/27
Project: Research project
Understand the Mechanism of SARS-CoV-2 Entry by Single-Molecule Approaches
Shrestha, P. (PI), Chattopadhyay, S. (CoI), Dutch, R. (CoI) & Richards, C. (CoI)
National Institute of Allergy and Infectious Diseases
7/11/24 → 7/31/29
Project: Research project
Validating long-read single-cell PIPseq as a technology to study T Cell Variant Dynamics in Aging and Dementia in Women (RPA Pilot / Seed Project)
Bachstetter, A. (PI), Nikolajczyk, B. (CoPI) & Ebbert, M. T. W. (CoPI)
University of Kentucky Neuroscience Research Priority Area
7/1/24 → …
Project: Research project
Emerging Themes for Research: CURE-KY (RPA Funding)
Messaoudi Powers, I. (PI) & Kuhs, K. (PI)
University of Kentucky Markey Cancer Center
6/1/24 → …
Project: Research project
Impacts of Borrelia Burgdorferi Gac Protein on Infectivity and Regulation of Virulence Protein Expression
Stevenson, B. (PI)
National Institute of Allergy and Infectious Diseases
6/1/24 → 4/30/26
Project: Research project
A Randomized, Doubleblind, Placebo-Controlled, Multinational, Phase 3 Study of the Efficacy and Safety of Inhaled Treprostinil in Subjects with Progressive Pulmonary Fibrosis (TETON-PPF)
Sen, P. (PI) & Sturgill, J. (CoI)
United Therapeutics Corporation
5/14/24 → 5/14/26
Project: Research project
Saturating Transposon Mutagenesis for Chlamydia
Fields, K. (PI) & Moseley, H. (CoI)
National Institute of Allergy and Infectious Diseases
5/10/24 → 3/31/26
Project: Research project
IPA: Durability and Mechanisms of Dengue Vaccine and Infection Mediated Immunity
Brien, J. (PI)
Veterans Affairs
4/1/24 → 3/31/26
Project: Research project
ARBOVERSE, A Data-driven Platform and Disease Modeling to Anticipating and Mitigating Arbovirus Emergence
de Souza, W. (PI)
Wellcome Trust
3/1/24 → 2/28/29
Project: Research project
Fatty Acid Synthase as a Novel Molecular Target for Colon Cancer Treatment
Gao, T. (PI), Lee, E. (CoI), Messaoudi Powers, I. (CoI), St Clair, D. (CoI), Wang, C. (CoI), Zaytseva, Y. (CoI) & Evers, B. M. (CoPI)
National Cancer Institute
3/1/24 → 2/28/29
Project: Research project
Dengue Virus mRNA Lipid Nanoparticle Vaccine
Pinto, A. (PI) & Brien, J. (CoI)
University of Illinois at Chicago
12/1/23 → 7/31/25
Project: Research project
Development of a Virus-Like Particle Vaccine for Powassan Virus
Pinto, A. (PI) & Brien, J. (CoI)
Oregon Health and Sciences University
10/1/23 → 5/31/26
Project: Research project
Value-Based Medical Student Education Training Program
Hoellein, A. (PI), Ballard III, J. (CoI), Cheever, T. (CoI), Danneman, H. (CoI), Garvy, B. (CoI), Haist, S. (CoI), Higgins, B. (CoI), Jackson, W. (CoI), Kudrimoti, A. (CoI), Sims, L. (CoI), Todd, R. (CoI), White, S. (CoI) & Ragsdale, J. (Former CoI)
Health Resources and Services Administration
9/30/23 → 6/30/27
Project: Research project
Impact Of Dysbiotic And Symbiotic Catabolism Of Luminal Amino Acids On Intestinal Epithelial Barrier Function And Inflammation
Alam, M. (PI), Barrett, T. (CoI), Evers, B. M. (CoI), Fields, K. (CoI), Gao, T. (CoI), Goretsky, T. (CoI) & Thorson, J. (CoI)
National Institute Diabetes & Digestive & Kidney
9/20/23 → 8/31/25
Project: Research project
Muscle and Physical Function Recovery after Acute Critical Illness (ALN 93.859)
Dupont-Versteegden, E. (PI), Kalema, A. (CoI), Kern, P. (CoI), Mayer, K. (CoI), Montgomery-Yates, A. (CoI) & Sturgill, J. (CoI)
National Institute Arthritis Musculoskeletal & Skin
9/18/23 → 8/31/28
Project: Research project
Muscle and Physical Function Recovery after Acute Critical Illness (ALN 93.846)
Dupont-Versteegden, E. (PI), Kalema, A. (CoI), Kern, P. (CoI), Mayer, K. (CoI), Montgomery-Yates, A. (CoI) & Sturgill, J. (CoI)
National Institute Arthritis Musculoskeletal & Skin
9/18/23 → 8/31/28
Project: Research project
Targeting the Immunosuppressive Tumor Microenvironment for Colorectal Cancer Treatment
Wang, Q. (PI), Bondada, S. (CoI), Higashi, R. (CoI), Lee, E. (CoI), Wang, C. (CoI), Weiss, H. (CoI) & Evers, B. M. (CoPI)
National Cancer Institute
9/1/23 → 8/31/28
Project: Research project
Collaborative Cross Mice as a New Model for Diverse Human Outcomes of St. Louis Encephalitis Virus Disease
Pinto, A. (PI)
University of California Davis
8/14/23 → 6/30/25
Project: Research project
HMPV/RSV Co-Infection: Effects on Replication and Viral Spread
Dutch, R. (PI) & Messaoudi Powers, I. (CoI)
National Institute of Allergy and Infectious Diseases
8/11/23 → 7/31/25
Project: Research project
POPI: Placenta, Opioids and Perinatal Implications
Messaoudi Powers, I. (PI), Allison, D. (CoI), Bada, H. (CoI), Gensel, J. (CoI), Hawk, G. (CoI), Shelman, N. (CoI), Sithisarn, T. (CoI), O'Brien, J. (CoPI) & Stromberg, A. (Former CoI)
National Institute on Drug Abuse
8/1/23 → 7/31/26
Project: Research project
Probiotic Nissle E. coli 1917 as antibiotic-alternative to combat antibiotic-resistant Campylobacter in the food chain
Helmy, Y. A. (PI), Messaoudi Powers, I. (CoI) & Thorson, J. (CoI)
National Institute of Food and Agriculture
8/1/23 → 7/31/25
Project: Research project
POPI: Placenta, Opioids and Perinatal Implications
O'Brien, J. (PI), Allison, D. (CoI), Bada, H. (CoI), Gensel, J. (CoI), Hawk, G. (CoI), Shelman, N. (CoI), Sithisarn, T. (CoI), Messaoudi Powers, I. (CoPI) & Stromberg, A. (Former CoI)
National Institute on Drug Abuse
8/1/23 → 7/31/26
Project: Research project
Invasion of the Enteric Nervous System by Neurotropic Listeria Monocytogenes
D'Orazio, S. (PI), Gensel, J. (CoI) & Richards, C. (CoI)
National Institute of Allergy and Infectious Diseases
7/1/23 → 6/30/28
Project: Research project
Genetic Screen To Define The Regulation Of Beta-Hemolysin Toxin Expression In Streptococcus Agalactiae
Korotkova, N. (PI) & Thorson, J. (CoI)
National Institute of Allergy and Infectious Diseases
5/19/23 → 4/30/26
Project: Research project
Chlamydia Type III Effectors Affecting the Host Actin-based Cytoskeleton
Fields, K. (PI), Piecoro, D. (CoI) & Wolf, K. (CoI)
National Institute of Allergy and Infectious Diseases
2/6/23 → 1/31/28
Project: Research project
Function of the Type 7 Secretion System in Group B Streptococcus
Korotkov, K. (PI) & Korotkova, N. (CoI)
National Institute of Allergy and Infectious Diseases
11/7/22 → 10/31/25
Project: Research project
Addressing Genetic Tractability and Species-specific Infection Biology in Chlamydia Pneumoniae
Fields, K. (PI) & Wolf, K. (CoI)
National Institute of Allergy and Infectious Diseases
11/7/22 → 6/30/25
Project: Research project
SBIR: Increasing Availability of Emulsion Adjuvants Via Synthetic Biolog
Chappell, J. (PI), Chambers, T. (CoI) & Woodward, J. (CoI)
Enepret Incorporated
10/11/22 → 8/29/25
Project: Research project
University of Kentucky SuRE Resource Center
Spear, B. (PI), D'Orazio, S. (CoI), Dupont-Versteegden, E. (CoI), Fardo, D. (CoI), Loria Kinsey, A. (CoI), Murphy, M. (CoI), Peterson, M. (CoI), Rice, B. (CoI), Smalls, B. (CoI), Stevens-Watkins, D. (CoI), Stratton, T. (CoI), Wolf, B. G. (CoI) & Nickell, M. (Former CoI)
National Institute of General Medical Sciences
9/5/22 → 8/31/27
Project: Research project
Admin Supplement: University of Kentucky SuRE Resource Center
Spear, B. (PI)
National Institute of General Medical Sciences
9/5/22 → 8/31/27
Project: Research project
NRSA T32: Training in Translational Research in Alzheimer's and Related Dementias (TRIAD)
Van Eldik, L. (PI), Cassis, L. (CoI), Gerhardt, G. (CoI), Saatman, K. (CoI), Schoenberg, N. (CoI), Spear, B. (CoI), Murphy, M. (CoPI) & Webb, N. (Former CoI)
National Institute on Aging
8/1/22 → 7/31/27
Project: Research project
Unliquidated Obligations Year 2: NRSA T32: Training in Translational Research in Alzheimer's and Related Dementias (TRIAD)
Van Eldik, L. (PI), Cassis, L. (CoI), Gerhardt, G. (CoI), Saatman, K. (CoI), Schoenberg, N. (CoI), Spear, B. (CoI), Murphy, M. (CoPI) & Webb, N. (Former CoI)
National Institute on Aging
8/1/22 → 7/31/27
Project: Research project
Novel Antiviral Mechanisms of the Interferon System
Chattopadhyay, S. (PI)
National Institute of Allergy and Infectious Diseases
5/25/22 → 4/30/28
Project: Research project
Combating Melanoma Resistance by Targeting ABL1/2
Plattner, R. (PI), Arays, R. (CoI), Gandhapudi, S. (CoI), Liu, J. (CoI), Richards, D. (CoI), Wang, C. (CoI), Yan, D. (CoI), Zhang, S. (CoI), Kolesar, J. (Former CoPI), COHEN, D. (Former CoI) & Wang, P. (Former CoI)
National Cancer Institute
5/23/22 → 4/30/27
Project: Research project
Bacterial Anti-inflammatory Lipid Mediators
Radka, C. (PI)
National Institute of Allergy and Infectious Diseases
2/17/22 → 8/31/26
Project: Research project
Mechanisms of Increased Susceptibility to Pulmonary Nontuberculous Mycobacterial Disease in the Elderly
Messaoudi Powers, I. (PI) & Dutch, R. (Former PI)
National Institute of Allergy and Infectious Diseases
12/1/21 → 3/31/26
Project: Research project
Diversity Supplement to Impact of Chronic Alcohol Consumption on the Functional and Epigenetic Landscapes of Monocytes and their Progenitors
Messaoudi Powers, I. (PI) & Sturgill, J. (CoI)
National Institute on Alcohol Abuse and Alcoholism
11/1/21 → 6/30/25
Project: Research project
Impact of Chronic Alcohol Consumption on the Functional and Epigenetic Landscapes of Monocytes and their Progenitors
Messaoudi Powers, I. (PI)
National Institute on Alcohol Abuse and Alcoholism
11/1/21 → 6/30/26
Project: Research project
Covid 19: Impact of Chronic Ethanol Consumption on Lung Functional and Immunological Landscape and Implication for Susceptibility to SARSCoV2 Infection
Messaoudi Powers, I. (PI)
National Institute on Alcohol Abuse and Alcoholism
11/1/21 → 6/30/25
Project: Research project
Covid 19: Researching COVID To Enhance Recovery: IDeA States COnsortium for clinical REsearch (ISCORE) Network
Whiteheart, S. (PI), Bumgardner, V. (CoI), Garvy, B. (CoI), Simmons, C. (CoI), Wood, J. (CoI) & Porterfield, J. (Former CoPI)
West Virginia University
10/1/21 → 5/23/25
Project: Research project
Dissemination of Intracellular and Extracellular Listeria from the Gut
D'Orazio, S. (PI)
National Institute of Allergy and Infectious Diseases
6/4/21 → 5/31/25
Project: Research project
Anti-Inflammatory Functions for Non-Transcriptional IRF3
Chattopadhyay, S. (PI)
National Institute of Allergy and Infectious Diseases
2/8/21 → 1/31/27
Project: Research project