Opthalmology

Finished

Non-canonical NLRP3 Inflammasome activation in Geographic Atrophy

Kerur, N.

7/1/13 → 6/30/14

Project: Research project

MyD88 inhibitory gene therapy for RPE degeneration--Yr 2

Ambati, J., Kerur, N. & Yasuma, T.

6/30/13 → 6/29/16

Project: Research project

MyD88 inhibitory gene therapy for RPE degeneration

Ambati, J., Kerur, N. & Yasuma, T.

6/30/13 → 6/29/14

Project: Research project

MyD88 inhibitory gene therapy for RPE degeneration--Yr 2

Ambati, J., Kerur, N. & Yasuma, T.

6/30/13 → 6/29/15

Project: Research project

A Phase III, Multi-National, Multi-Center, Randomized, Masked, Controlled, Safety and Efficacy Study of a Fluocinolone Acetonide Intravitreal

Kleinman, M., Blackburn, P., Fraser, C., Higgins, E. & Thompson, K.

PPD Development Inc

5/24/13 → 8/31/16

Project: Research project

Open-Label Pilot Safety Study of AP-104IVT (Sustained-Release Fluticasone, Intravitreal) after a Single Intravitreal Injection in Patients with Diabetic Macular Edema

Pearson, P., Blackburn, P. & Higgins, E.

Auritec Pharmaceuticals Incorporated

4/10/13 → 7/31/14

Project: Research project

SCOPE: Diabetes Research Center

Bastos de Carvalho, A.

Washington University in St. Louis

2/23/13 → 11/30/19

Project: Research project

Platelet Metabolism in Diabetes Mellitus

Wang, Q.

Washington University in St. Louis

2/23/13 → 11/30/22

Project: Research project

Therapeutic MyD88 Inhibition in a Novel Model of Dry Age-Related Macular Degeneration

Ambati, J.

12/1/12 → 8/31/13

Project: Research project

Safety of Modified Extended Release Latanoprost Implant in Rabbit Eyes

Kleinman, M., Moss, P. & Deokule, S.

pSivida Corp

8/20/12 → 4/30/14

Project: Research project

Effect of Corneal Preservation Time on Long-Term Graft Success Cornea Preservation Time Study (CPTS) Protocol (EYE BANK)

VanMeter, W., Katz, D. & White, H.

Jaeb Center for Health Research Foundation Incorporated

6/28/12 → 12/31/17

Project: Research project

Effect of Corneal Preservation Time on Long-Term Graft Success Cornea Preservation Time Study (CPTS) Protocol

VanMeter, W. & Katz, D.

Jaeb Center for Health Research Foundation Incorporated

6/28/12 → 8/31/17

Project: Research project

SBIR: Evaluation of continuous intraocular pressure monitor in a rabbit eye: a pilot study

Deokule, S.

6/1/12 → 3/30/13

Project: Research project

Supplement: Functional Studies of Dicer1 and Alu RNA in Geographic Atrophy

Ambati, J.

2/1/12 → 1/31/14

Project: Research project

Functional Studies of DICER1 and Alu RNA in Geographic Atrophy

Ambati, J.

2/1/12 → 1/31/16

Project: Research project

Functional Studies of DICER1 and Alu RNA in Geographic Atrophy

Ambati, J.

2/1/12 → 6/30/16

Project: Research project

Functional Studies of Dicer1 and Alu RNA in Geographic Atrophy - Adm Supplement

Ambati, J.

2/1/12 → 1/31/14

Project: Research project

Soluble VEGFR-2 as an Endogenous Inhibitor of Retinal Lymphatics

Baffi, J.

9/30/11 → 6/30/12

Project: Research project

A Prospective Longitudinal Observational Study to Assess the Development of OSD (Sahara)

Deokule, S. & Sanders, S.

Merck and Company Inc

9/21/11 → 9/21/15

Project: Research project

C-01-11-008: An Open Label, Multi-center Extension Study of the Safety and Utility of the New Inserter of ILUVIEN (Fluocinolone Acetonide Intravitreal Insert) 0.19 mg and the Safety of ILUVIEN in Subjects with Diabetic Macular Edema

Blackburn, P. & Pearson, P.

Alimera Sciences Incorporated

9/1/11 → 8/31/14

Project: Research project

Identification and Therapeutic Targeting of Pathogenic Nucleic Acids in AMD

Kleinman, M.

7/1/11 → 6/30/13

Project: Research project

Identification and Therapeutic Targeting of Pathogenic Nucleic Acids in AMD

Kleinman, M.

7/1/11 → 6/30/12

Project: Research project

Identification and Therapeutic Targeting of Pathogenic Nucleic Acids in AMD

Kleinman, M.

7/1/11 → 6/30/14

Project: Research project

A Phase 1, Open-Label, Dose Escalation Study to Evaluate the Safety and Tolerability of Latanoprost Sustained Release (SR) Insert in Patients with Primary Open Angle Glaucoma (POAG) or Ocular Hypertension

Moore, D. & Deokule, S.

pSivida Corp

6/14/11 → 10/24/14

Project: Research project

Clinical Approaches and Translational Advances in Opthalmology Mini Symposium

Ambati, J. & Norton, J.

1/7/11 → 12/31/11

Project: Research project

ARRA: Targeted Nanoparticles Delivering Intraceptor-Expressing Plasmids to Regress Choroidal Neovasculariz

Ambati, J.

8/1/10 → 6/30/11

Project: Research project

Endorepellin - Antiangiogenic Effects in Oxygen Induced Retinopathy

Raisler, B.

7/1/10 → 6/30/12

Project: Research project

A Phase 1 Open Label, Dose Escalation Study to Evaluate the Safety and Tolerability of Latanoprost Sustained Release Insert in Patients with Primary Open Angle Glaucoma or Ocular Hypertension

Deokule, S.

6/1/10 → 3/31/12

Project: Research project

Prevention of Laser-Induced Choroidal Neovascularization by CVX-060

Ambati, J.

5/20/10 → 6/30/11

Project: Research project

CCR3 biology and imaging applied to Chorodial Neovascularization in Age-Related Macular Degeneration

Baffi, J.

4/1/10 → 6/25/12

Project: Research project

Endogenous Specific Inhibitor of Corneal Lymphangiogenesis

Ambati, J., Baffi, J. & Vander Kooi, C.

4/1/10 → 3/31/14

Project: Research project

Endogenous Specific Inhibitor of Corneal Lymphangiogenesis

Ambati, J., Baffi, J. & Vander Kooi, C.

4/1/10 → 3/31/12

Project: Research project

Release of Latanaprost from an Extended Release Subconjunctival Implant and its Effects on Intraocular

Deokule, S.

3/23/10 → 2/28/12

Project: Research project

CCR3 as an Early Detection Target in Age Related Macular Degeneration

Baffi, J.

3/1/10 → 3/1/12

Project: Research project

A Phase I Open Label, Dose Escalation Trial of QPI-1007 Delivered by a Single Intravitreal Injection to Patients with Optic Nerve Athrophy (Stratum I) and Acute Non-Arteritic Anterior Ischemic Optic Neuopathy (NAION) (Stratum II)

Deokule, S.

2/26/10 → 2/28/14

Project: Research project

Transitional Advances in the Diagnosis and Treatment of Neovascular Diseases of the Eye: Medical Education

Ambati, J.

1/22/10 → 12/18/10

Project: Research project

Senior Scientific Investigator Award

Ambati, J.

1/1/10 → 12/31/10

Project: Research project

Clinical Approaches and Scientific Advances in Ophthalmology: Independent Medical Education

Ambati, J.

11/20/09 → 12/31/10

Project: Research project

ARRA: CCR3: A molecular maker for neovascular AMD

Ambati, J.

9/30/09 → 9/29/12

Project: Research project

A Randomized, Double-Masked, Pilot Study of the Safety and Efficacy of 0.5 ug/day and .02 ug/day IIuvien (Fluocinolone Acetonide Intravitreal Insert) 0.19mg in Subjects with Macular Edema Secondary to Retinal Vein Occlusion

Pearson, P.

Alimera Sciences Incorporated

9/4/09 → 8/31/14

Project: Research project

Novel TLR3 inhibitors for geographic atrophy of age-related macular degeneration

Ambati, J. & Baffi, J.

8/1/09 → 6/30/12

Project: Research project

A Study of the Safety and IOP Lowering Efficacy of Anectortave Acetate in Patients with Open-Angle Glaucoma

Deokule, S. & Sanders, S.

Alcon Laboratories Inc

7/1/09 → 12/31/09

Project: Research project

A Randomized, Placebo Controlled, Double-Masked, Multicenter of Microplamin Intavitreal Injection for Non-Surgical Treatment of Focal Vitreomacular Adhesion

Pearson, P. & Blackburn, P.

Thrombogenics

3/18/09 → 7/31/10

Project: Research project

Short non-Interfering RNAs as Novel Therapies for Age Related Macular Degeneration

Ambati, J.

1/1/09 → 12/31/13

Project: Research project

Research To Prevent Blindness Unrestricted Grant

Pearson, P. & Ambati, J.

Research to Prevent Blindness (RPB)

1/1/09 → 12/31/14

Project: Research project

A 6 Day, Phase 3, Multicenter, Randomized, Double-Masked, Parallel Study to Compare the Safety and Efficacy of Gatifloxacin 0.5% Ophthalmic Solution BID with that of Vehicle in the Treatment of Acute Bacterial Conjunctivitis

Capoor, S.

Allergan Pharmaceuticals Inc

10/1/08 → 12/31/08

Project: Research project

Fellowship for Albuquerque: Establishing the Role of the Novel Endogenous sVEGFR-2 in Corneal Lymphangiogenesis and Transplant Rejection

Ambati, J. & Albuquerque, R.

7/1/08 → 6/30/09

Project: Research project

The Hetergeneous Immunovascular Effects of Small Interfering RNA in the Posterior Segment

Ambati, J. & Kleinman, M.

7/1/08 → 6/30/09

Project: Research project

Intrinsic Anti-Angiogenic Activity of siRNA - Supplemental - Equipment

Ambati, J.

4/1/08 → 3/31/11

Project: Research project

Intrinsic Anti-Angiogenic Activity of siRNA

Ambati, J.

4/1/08 → 3/31/13

Project: Research project

Opthalmology

Grants and Contracts

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