Pharmaceutical Sciences

National Institute of Allergy and Infectious Diseases

7/1/24 → 6/30/25

Project: Research project

Interactions Between Drug Combinations and Resistance Acquisition Risk for Antimalarial ATP4 Inhibitors

Guy, R. K. (PI)

6/7/24 → 5/31/29

Project: Research project

Leveraging Preclinical Repeated Blast Traumatic Brain Injury to Model Military-Relevant Post-Traumatic Epilepsy

Hubbard, W. (PI) & Bauer, B. (CoI)

Army Medical Research and Development Command

6/1/24 → 5/31/27

Project: Research project

Regulation of Cocaine Use by Astrocyte Voltage-Gated Channels

Ortinski, P. (PI) & Turner, J. (CoI)

National Institute of Neurological Disorders & Stroke

4/1/24 → 3/31/26

Project: Research project

Harnessing Engineered Drug-Free Polymeric Nanoformulations To Reprogram Innate Immune Cells For Spinal Trauma

Park, J. (PI) & Gensel, J. (CoI)

3/20/24 → 2/28/29

Project: Research project

Exploiting Emerging Supramolecules as In Vivo Sequestrants to Induce Drug Reversal

Prisinzano, T. (PI), Alilain, W. (CoI) & Bardo, M. (CoI)

Reversal Therapeutics Incorporated

3/5/24 → 12/31/24

Project: Research project

NRSA Fellowship Emily Prantzalos: Role of Neuregulin 3-ErbB4 Signaling in a Murine Model of Co-Morbid Nicotine Dependence and Schizophrenia

Turner, J. (PI)

National Institute of Neurological Disorders & Stroke

1/12/24 → 1/11/27

Project: Research project

Cannabidiol (CBD) as a Potential Therapeutic for Experimental Subarachnoid Hemorrhage

Roberts, J. (PI), Bauer, B. (CoI), Fraser, J. (CoI), McLouth, C. (CoI) & Sompol, P. (CoI)

12/5/23 → 11/30/25

Project: Research project

Pdcd4-Rictor Interaction in Suppression of Lung Tumorigenesis

Yang, H.-S. (PI), Chen, L. (CoI), Fan, W.-M. (CoI), Hao, Z. (CoI), Lee, E. (CoI), Liu, X. (CoI) & Zhan, C.-G. (CoI)

National Institute Diabetes & Digestive & Kidney

9/20/23 → 8/31/28

Project: Research project

Impact Of Dysbiotic And Symbiotic Catabolism Of Luminal Amino Acids On Intestinal Epithelial Barrier Function And Inflammation

Alam, M. (PI), Barrett, T. (CoI), Evers, B. M. (CoI), Fields, K. (CoI), Gao, T. (CoI), Goretsky, T. (CoI) & Thorson, J. (CoI)

9/20/23 → 8/31/25

Project: Research project

Bisphenol-Induced Blood-Brain Barrier Dysfunction in Alzheimer’s Disease

Hartz, A. (PI), Bauer, B. (CoI), Gold, B. (CoI), Hennig, B. (CoI), Kryscio, R. (CoI) & Pearson, K. (CoI)

National Institute of Neurological Disorders & Stroke

9/15/23 → 7/31/28

Project: Research project

Combination of SJ733 with Tafenoquine as a Possible 1 or 2 Dose Radical Cure for P. Vivax Malaria

Guy, R. K. (PI) & Bush, H. (Former CoI)

Eisai Incorporated

9/12/23 → 9/30/25

Project: Research project

Planning Study for the Development of Sigma 2 Ligands as Analgesics

Tidgewell, K. (PI)

National Institute of Neurological Disorders & Stroke

9/11/23 → 8/31/25

Project: Research project

Fellowship-Emily Prantzalos:Role of Neuregulin 3-ErbB4 Signaling in a Murine Model of Co-Morbid Nicotine Dependence and Schizophrenia

Turner, J. (PI)

American Foundation for Pharmaceutical Education

9/1/23 → 5/31/25

Project: Research project

Long-Acting Aldicarb Hydrolase as a Medical Countermeasure for Aldicarb Poisoning

Zheng, F. (PI) & Zhan, C.-G. (CoPI)

National Institute of Neurological Disorders & Stroke

9/1/23 → 8/31/25

Project: Research project

Probiotic Nissle E. coli 1917 as antibiotic-alternative to combat antibiotic-resistant Campylobacter in the food chain

Helmy, Y. A. (PI), Messaoudi Powers, I. (CoI) & Thorson, J. (CoI)

National Institute of Food and Agriculture

8/1/23 → 7/31/25

Project: Research project

Neurobehavioral Mechanisms Underlying Xylazine and Fentanyl Co-use and Withdrawal

Gipson-Reichardt, C. (PI), Moseley, H. (CoI), Prisinzano, T. (CoI) & Hinds, T. (CoPI)

National Institute of Neurological Disorders & Stroke

6/15/23 → 4/30/28

Project: Research project

The Role of Macrophage Metabolism and Age in Recovery from Spinal Cord Injury

Gensel, J. (PI), Johnson, L. (CoI), McClintock, T. (CoI), Sullivan, P. (CoI), Venditto, V. (CoI), Wilson, M. (CoI) & Patel, S. (CoPI)

6/1/23 → 5/31/28

Project: Research project

Genetic Screen To Define The Regulation Of Beta-Hemolysin Toxin Expression In Streptococcus Agalactiae

Korotkova, N. (PI) & Thorson, J. (CoI)

National Institute of Allergy and Infectious Diseases

5/19/23 → 4/30/25

Project: Research project

Center of Biomedical Research Excellence in CNS Metabolism - Administrative Core

Sullivan, P. (PI), Bachstetter, A. (CoI), Bauer, B. (CoI), Dutch, R. (CoI), Hubbard, W. (CoI), Johnson, L. (CoI), Nikolajczyk, B. (CoI), Norris, C. (CoI), Patel, S. (CoI), Schmitt, F. (CoI), Selenica, M.-L. (CoI), Slevin, J. (CoI), Wilcock, D. (CoI) & Yamasaki, T. (CoI)

University of Maryland at College Park

5/15/23 → 2/29/28

Project: Research project

Development of Alginate Biosynthesis Inhibitors and Identification of their Targets

Garneau-Tsodikova, S. (PI)

5/1/23 → 4/30/25

Project: Research project

Development of Actinomycetes-Derived Antimicrobial Compounds as Eco-Friendly Solutions for the Management of Plant and Food-Borne Pathogens

Mahmoud, K. A. (PI) & Thorson, J. (CoPI)

University of Maryland

5/1/23 → 4/30/26

Project: Research project

Effects of HIV-1 Tat Protein and Methamphetamine on VMAT2-mediated Dopamine Transmission in the Context of NeuroHIV and Drug Abuse

Zhan, C.-G. (PI)

University of South Carolina

4/1/23 → 1/31/28

Project: Research project

Mechanism and Therapeutic Potential of CBD to Repair Blood-Brain Barrier Dysfunction in Epilepsy

Bauer, B. (PI), Abner, E. (CoI), Hartz, A. (CoI), Sunderam, S. (CoI) & Pauly, J. (Former CoI)

National Institute of Neurological Disorders & Stroke

4/1/23 → 3/31/25

Project: Research project

SBIR: Increasing Availability of Emulsion Adjuvants Via Synthetic Biolog

Chappell, J. (PI), Chambers, T. (CoI) & Woodward, J. (CoI)

Enepret Incorporated

10/11/22 → 8/29/25

Project: Research project

Development of a Highly Selective mPGES-1 Inhibitor as an Effective Non-Opioid Treatment of Chronic Pain

Zhan, C.-G. (PI) & Zheng, F. (CoI)

Army Research Office

9/15/22 → 9/14/26

Project: Research project

Ghrelin Deacylase as a Treatment for Opioid Polysubstance Abuse

Zhan, C.-G. (PI) & Zheng, F. (CoPI)

National Institute on Aging

7/1/22 → 6/30/25

Project: Research project

Blood-Brain Barrier Repair in Alzheimer's Disease with Epilepsy

Hartz, A. (PI), Abner, E. (CoI), Gold, B. (CoI), Kryscio, R. (CoI), Nelson, P. (CoI), Schmitt, F. (CoI) & Bauer, B. (CoPI)

5/1/22 → 4/30/27

Project: Research project

Neurocognitive Impairments Resulting from Adolescent Prescription Opioid Use Disorder: Longitudinal Impact, Neural Mechanisms, and Comorbidities

McLaurin, K. (PI)

4/1/22 → 3/31/27

Project: Research project

Development of Agents for Synthetic Opioid Overdose

Prisinzano, T. (PI), Alilain, W. (CoI), Bardo, M. (CoI) & Turner, J. (CoI)

National Institute on Alcohol Abuse and Alcoholism

9/1/21 → 7/31/25

Project: Research project

Neuropeptide-Dependent Parabrachial Control of the BNST During Alcohol Abstinence-Induced Negative Affect

Jaramillo, A. (PI)

8/6/21 → 5/31/26

Project: Research project

Functional and Genomic Signatures of Escalated Fentanyl Use

Ortinski, P. (PI) & Turner, J. (CoPI)

National Institute of Neurological Disorders & Stroke

3/15/21 → 12/31/25

Project: Research project

Macrophage Depletion Therapy for Spinal Cord Injury

Gensel, J. (PI), Venditto, V. (CoI) & Alilain, W. (CoPI)

3/15/21 → 11/30/25

Project: Research project

Functional and Genomic Signatures of Escalated Fentanyl Use

Turner, J. (PI), Bumgardner, V. (CoI), Charnigo, R. (CoI), Bardo, M. (CoPI) & Ortinski, P. (CoPI)

3/15/21 → 12/31/25

Project: Research project

Functional and Genomic Signatures of Escalated Fentanyl Use

Bardo, M. (PI) & Turner, J. (CoPI)

National Heart Lung and Blood Institute

3/15/21 → 12/31/25

Project: Research project

Pharmacological Mechanistic Insights into Thoracic Aortic Aneurysm

Sheppard, M. (PI), Cassis, L. (CoI), Daugherty, A. (CoI) & Graf, G. (CoI)

12/18/20 → 11/30/25

Project: Research project

Development of a Long-acting Enzyme Therapy for Treatment of Cocaine Abuse

Zhan, C.-G. (PI), Walsh, S. (CoI) & Zheng, F. (CoI)

8/15/20 → 4/30/25

Project: Research project

Carry-Forward Scope: Development of a Long-acting Enzyme Therapy for Treatment of Cocaine Abuse

Zhan, C.-G. (PI), Walsh, S. (CoI) & Zheng, F. (CoI)

National Library of Medicine

8/15/20 → 4/30/25

Project: Research project

Advanced End-to-End Relation Extraction with Deep Neural Networks

Kavuluru, R. (PI), Black, P. (CoI), Xu, L. H. R. (CoI), Kakani, E. (Former CoI) & Talari, P. (Former CoI)

7/1/20 → 3/31/25

Project: Research project

Understanding the Role of Immune Complexes Between Apolipoprotein A-I and IgG in Atherosclerotic Cardiovascular Disease

Venditto, V. (PI), Daugherty, A. (CoI), Temel, R. (CoI) & Thompson, K. (CoI)

National Heart Lung and Blood Institute

7/1/20 → 6/30/25

Project: Research project

Novel Therapeutic Strategies to Resolve Neurovascular Inflammation and Repair Blood-Brain Barrier Dysfunction in Epilepsy

Bauer, B. (PI), Hartz, A. (CoI), Kryscio, R. (CoI), Sunderam, S. (CoI), Lin, A. L. (Former CoI), Pauly, J. (Former CoI) & Smith, B. (Former CoI)

National Institute of Neurological Disorders & Stroke

6/15/20 → 3/31/26

Project: Research project

Mechanistic and Pharmacologic Studies of Selective Mithramycin Analogues Targeting EWS-FLI1 in Ewing Sarcoma

Tsodikov, O. (PI), Badgett, J. (CoI), Rohr, J. (CoPI), Leggas, M. (Former PI), Wang, C. (Former CoI) & Weiss, H. (Former CoI)

6/1/20 → 5/31/25

Project: Research project

Scope: Rohr: Mechanistic and Pharmacologic Studies of Selective Mithramycin Analogues Targeting EWS-FLI1 in Ewing Sarcoma

Rohr, J. (PI)

6/1/20 → 5/31/25

Project: Research project

Computational Core Scope: COBRE in Pharmaceutical Research and Innovation

Thorson, J. (PI)

3/1/20 → 1/31/25

Project: Research project

Kristen McLaurin Scope: COBRE in Pharmaceutical Research and Innovation

McLaurin, K. (PI) & Thorson, J. (CoI)

3/1/20 → 1/31/25

Project: Research project

Lindsay Czuba Scope: COBRE in Pharmaceutical Research and Innovation

Czuba, L. (PI) & Thorson, J. (CoI)

3/1/20 → 1/31/25

Project: Research project

Yosra Mohamed (Helmy) Scope: COBRE in Pharmaceutical Research and Innovation

Helmy, Y. A. (PI) & Thorson, J. (CoI)

3/1/20 → 1/31/25

Project: Research project

Translational Core Scope: COBRE in Pharmaceutical Research and Innovation

Thorson, J. (PI)

3/1/20 → 1/31/25

Project: Research project

Anel Jaramillo Scope: COBRE in Pharmaceutical Research and Innovation

Jaramillo, A. (PI) & Thorson, J. (CoI)