Research Priority Initiative

BeiGene USA Incorporated

10/26/23 → 10/26/25

Project: Research project

Aberrant Fucosylation is a Critical Feature of Neuroblastoma Immune Evasion

Rellinger, E., Allison, D. & Wang, C.

V Foundation

10/15/23 → 10/15/26

Project: Research project

23-MULTI-60-BT-PMC (BCA101X1101): First-in-Human, Phase 1/1b, Open-label, Multicenter Study of Bifunctional EGFR/TGFbeta; Fusion Protein BCA101 Monotherapy and in Combination Therapy in Patients with EGFR-Driven Advanced Solid Tumors

Bicara Therapeutics Incorporated

10/3/23 → 10/3/25

Project: Research project

23-MEL-13-VMT-PMC (VMT01-T101): A Phase I/IIa, First-In-Human, Multi-Center Dose Escalation and Dose Expansion Study of [203/212Pb]VMT01 Receptor-Targeted, Image-Guided Alpha-Particle Therapy in Patients With Previously Treated Unresectable or Metastatic

Arays, R.

Viewpoint Molecular Targeting Incorporated

9/21/23 → 9/21/25

Project: Research project

Pdcd4-Rictor Interaction in Suppression of Lung Tumorigenesis

Yang, H., Chen, L., Fan, W., Hao, Z., Lee, E., Liu, X. & Zhan, C.

9/20/23 → 8/31/28

Project: Research project

SEER - Linked Virtual Tissue Repository (VTR) Program

Tucker, T.

Caribou Biosciences Incorporated

9/15/23 → 9/14/24

Project: Research project

23-NHL-31-CB-PMC: CB-10A, A Phase 1, Multicenter, Open-Label Study of CB-010, a CRISPR-Edited Allogeneic Anti-CD19 CAR-T Cell Therapy in Patients with Relapsed/Refractory B Cell Non-Hodgkin Lymphoma (ANTLER)

Yalniz, F.

9/8/23 → 9/8/25

Project: Research project

CCSG Pilot: Determining Mechanisms of Immunotherapy Resistance in KEAP1 and LKB1 Mutant Lung Cancers

Brainson, C., Durbin, E. B., Hao, Z., Jeong, J. C. & Liu, J.

9/1/23 → 6/30/24

Project: Research project

CCSG Pilot: Improving Anti-PD1 Therapy in Triple-Negative Breast Cancer

Liu, X., Liu, J. & Marcinkowski, E.

9/1/23 → 6/30/24

Project: Research project

The PLOD2/Succinate Axis in Cancer Cell Plasticity and Stemness

Xu, R., Bocklage, T., Chen, L. & Guo, H.

9/1/23 → 8/31/28

Project: Research project

Targeting NNMT to Inhibit Obesity-Associated Breast Cancer Development and Progression

Zhou, B., Lane, A., St Clair, D. & Wang, C.

Department of Defense

9/1/23 → 8/31/26

Project: Research project

Targeting RSK-TRIM28-E2F1 Axis Overcomes CDK4/6 Inhibitor Resistance in Lethal RB1 Deficient Prostate Cancer

Fong, K. W., Allison, D., Liu, J. & Liu, X.

V Foundation

9/1/23 → 9/1/26

Project: Research project

Targeting the Immunosuppressive Tumor Microenvironment for Colorectal Cancer Treatment

Wang, Q., Bondada, S., Higashi, R., Lee, E., Wang, C., Weiss, H. & Evers, B. M.

National Institute on Drug Abuse

9/1/23 → 8/31/28

Project: Research project

IMGN853-0421/GOG-3078: Randomized, Multicenter, Open-label, Phase 3 study of Mirvetuximab Soravtansine in Combination with Bevacizumab Versus Bevacizumab Alone as Maintenance Therapy for Patients with FRa-positive Recurrent Platinum-sensitive Epithelial o

Miller, R.

ImmunoGen Inc

8/30/23 → 8/30/25

Project: Research project

The University of Kentucky Racial Equity Initiative Coordinating Center

Stevens-Watkins, D., Adatorwovor, R., Canedo, J., Francis, D., Hargons, C., Knudsen, H., Oser, C., Stoops, W., Vickers-Smith, R. & Wolf, B. G.

8/15/23 → 6/30/28

Project: Research project

23-BRE-56-AZ (D8531C00002): A Phase III, Open-Label, Randomised Study to Assess the Efficacy and Safety of Extended Therapy With Camizestrant Versus Standard Endocrine Therapy (Aromatase Inhibitor or Tamoxifen) in Patients With ER+/HER2- Early Breast Can

Moss, J.

NSABP Foundation

8/4/23 → 8/4/25

Project: Research project

Pathways, a Hope-Based Intervention to Support Personal Goal Pursuit, Mental Health, and Quality of Life during Advanced Lung Cancer Treatment

McLouth, L., Arnold, S., Burris, J., McFarlin, J., Shelton, B. & Stapleton, J.

7/25/23 → 6/30/28

Project: Research project

23-NHL-30-OP (ONO-4059-09): An Open-label Phase II Study to Investigate the Efficacy, Safety, and Pharmacokinetics of Tirabrutinib in Patients with Primary Central Nervous System Lymphoma (PCNSL)

Munker, R.

Ono Pharmaceutical

7/24/23 → 7/24/25

Project: Research project

23-LUN-132-RBI-PMC: Phase 1b Single Arm, Open-Label Trial of RYZ101 in Combination with Carboplatin + Etoposide + Atezolizumab in Subjects with Somatostatin Receptor Expressing (SSTR+) Extensive Stage Small Cell Lung Cancer (ES-SCLC)

Hao, Z.

RayzeBio Incorporated

7/18/23 → 7/18/25

Project: Research project

23-MULTI-59-LTI(LTSA1-P02): A Phase 2a, Double-blind, Placebo-controlled, Multi-center, Randomized Study Evaluating LSTA1 When Added to Standard of Care (SoC) Versus Standard of Care Alone in Subjects with Advanced Solid Tumors (BOLSTER)

Lisata Therapeutics Incorporated

7/18/23 → 7/18/25

Project: Research project

Empathic Communication Skills Training to Reduce Lung Cancer Stigma

Mullett, T. & Burris, J.

Memorial Sloan Kettering Cancer Center

7/14/23 → 7/14/28

Project: Research project

23-LUN-133-LB-PMC: LB2102-1001, A First in Human Dose Escalation and Cohort Expansion Study of DLL3-directed Chimeric Antigen Receptor T-cells in Subjects With Extensive Stage Small Cell Lung Cancer

Hao, Z.

Legend Biotech USA Incorporated

7/10/23 → 7/10/25

Project: Research project

Targeting Lung Fibrosis with Epigenetic Therapy

Brainson, C., Bachert, S. & Liu, J.

American Lung Association

7/1/23 → 6/30/25

Project: Research project

Overcoming Therapeutic Resistance in Lung Cancer Using Novel Combination Therapies

Brainson, C. & Liu, J.

Markey Cancer Center Foundation

7/1/23 → 7/31/24

Project: Research project

Roles of mRNA Transfer in Cancer Cell-Platelet Communication

Xu, R., Liu, X. & Trinkle, C.

KY Cabinet for Health and Family Services

7/1/23 → 6/30/28

Project: Research project

Summer Health Experience (SHE) in Oncology Program

Vanderford, N.

American Cancer Society

7/1/23 → 12/31/23

Project: Research project

Evaluating Coverage and Cost of Care Links (C4299): FY24 Evaluating CC Links

Edward, J., D'Orazio, J., Northrip, K. & Shelton, B.

7/1/23 → 6/30/25

Project: Research project

Developing New Therapies for Metatsic Melanoma

Plattner, R., Goellner, E., Liu, J. & Richards, D.

Markey Cancer Center Foundation

7/1/23 → 7/31/24

Project: Research project

Targeting the Plk1/Pdcd4/mTORC2 Signaling to Treat Castration-Resistant Prostate Cancer

Yang, H., Allison, D., Chen, L. & Liu, X.

7/1/23 → 6/30/28

Project: Research project

Targeting the Plk1/Pdcd4/mTORC2 Signaling to Treat Castration-Resistant Prostate Cancer

Liu, X., Allison, D., Chen, L. & Yang, H.

KY Cabinet for Health and Family Services

7/1/23 → 6/30/28

Project: Research project

FY24 Spatial Transcriptomic Characterization of Pediatric Brain Tumors in Kentucky

Wang, C., Durbin, E. B., Harrison, D., Jeong, J. C., Liu, J., Neltner, J., Tucker, T., Villano, J. & Zhang, S.

7/1/23 → 6/30/24

Project: Research project

Kentucky Lung Cancer Education Awareness Detection Survivorship (LEADS) Prevention and Early Detection and QUILS (Quality Implementation of Lung Cancer Screening)

Knight, J. & Mullett, T.

Anthem Health Plans of Kentucky Inc

6/30/23 → 6/29/24

Project: Research project

Health Equity in Fertility Specialty Care Among Cancer Survivors (00015476)

Saltzman, A. & Durbin, E. B.

MD Anderson Cancer Center

6/28/23 → 12/31/27

Project: Research project

23-LEUK-22-GS: GS-US-546-5857, Enhance-2_A Phase 3, Randomized, Open-Label Study Evaluating the Safety and Efficacy of Magrolimab in Combination with Azacitidine versus Physician s Choice of Venetoclax in Combination with Azacitidine or Intensive Chemothe

Qasrawi, A.

Gilead Sciences Inc

6/27/23 → 6/27/25

Project: Research project

23-NHL-29-DO: MK2140-003, A Phase 2/3 Multicenter, Open-label, Randomized, Active-Control Study of Zilovertamab Vedotin (MK-2140) in Combination With Standard of Care in Participants With Relapsed or Refractory Diffuse Large B-Cell Lymphoma (waveLINE-003)

Iragavarapu, C.

Merck Sharp & Dohme Corporation

6/26/23 → 6/26/25

Project: Research project

23-NET-01-VMT-PMC(VMT-alpha-NET-T101): A Phase I/IIa First-in-Human Study of [212Pb]VMT-alpha-NET Targeted Alpha-Particle Therapy for Advanced SSTR2 Positive Neuroendocrine Tumors

Anthony, L.

Viewpoint Molecular Targeting Incorporated

6/22/23 → 6/22/25

Project: Research project

Center for Appalachian Research in Environmental Sciences: Administrative Core

Hahn, E., Arnett, D., Bauer, J., Cassis, L., Christian, J., Cox, N., Curry, T., DiPaola, R., Dignan, M., Evers, B. M., Fan, W., Haynes, E., Hoover, A., Kern, P., May, B., Miller, J., Pearson, K., Pennell, K., Richardson, K., Sanderson, W., Schoenberg, N., Stanifer, S., Stratton, T., Swanson, H., Talbert, J., Unrine, J., Heath, E., Stanley, S. & Stromberg, A.

National Institute of Environmental Health Sciences

6/3/23 → 4/30/28

Project: Research project

Study Of PTPRF-Mediated Regulation Of Wnt Signaling

Gao, T., Barrett, T. & Wang, C.

National Institute of General Medical Sciences

6/1/23 → 3/31/27

Project: Research project

22-HN-37-MSD (689-07): A Phase III, Randomized, Open-label Study to Evaluate Pembrolizumab as Neoadjuvant Therapy and in Combination With Standard of Care as Adjuvant Therapy for Stage III-IVA Resectable Locoregionally Advanced Head and Neck Squamous Cell

Merck Sharp & Dohme Corporation

5/11/23 → 5/10/25

Project: Research project

Paper Computers: The Story of Slide Charts in American History-OVPR CURATE Program

Cagle, L.

5/1/23 → 4/30/24

Project: Research project

Indexing Together: Using OHMS to Engage Community-OVPR CURATE Program

Boyd, D.

5/1/23 → 4/30/24

Project: Research project

Exploring the Nexus of Representation, Organizational Images, and Recruitment into Government - OVPR CURATE Program

Hameduddin, T.

5/1/23 → 4/30/24

Project: Research project

Explore First: Supporting First-Generation Student Career Exploration through Study Abroad- OVPR CURATE Program

Johnson, K.

5/1/23 → 4/30/24

Project: Research project

Force-Free Dog Training and Social Justice- OVPR CURATE Program

Yam, S.

5/1/23 → 4/30/24

Project: Research project

Surveillance, Epidemiology, and End Results (SEER) Program

Durbin, E. B., Huang, B., Shelton, B., Tucker, T. & Ross, F.