Research Priority Initiative

University of Kentucky

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24-HN-40-MSD (007-00): A Phase 2/3, Adaptive, Randomized, Open-Label, Clinical Study to Evaluate Neoadjuvant and Adjuvant V940 (mRNA-4157) in Combination with Pembrolizumab (MK- 3475) Versus Standard of Care, and Pembrolizumab Monotherapy in Participants
Arnold, S.
Merck Sharp & Dohme Corporation
9/3/24 → 9/3/26
Project: Research project
Developing New Therapeutic Approaches for BRAFV600E Colorectal Cancer
Zaytseva, Y., Lee, E. & Wang, C.
Colorectal Cancer Alliance
9/1/24 → 8/31/26
Project: Research project
24-GI-136-AZ (D9802C0001): A Phase III Multi-center, Open-label, Sponsor-blinded, Randomized Study of AZD0901 Monotherapy Compared with Investigator s Choice of Therapy in Second- or Later-Line Adult Participants with Advanced/Metastatic Gastric or Gastr
Patel, R.
AstraZeneca Pharmaceuticals LP (domestic)
8/30/24 → 8/30/26
Project: Research project
NCI Collaboration
Burus, J.
National Cancer Institute
8/23/24 → 8/22/25
Project: Research project
Targeting Lung Fibrosis Using Epigenetic Therapy
Brainson, C., Allison, D., Beswick, E., Liu, J., Sturgill, J., Waters, C. & Weiss, H.
National Heart Lung and Blood Institute
8/15/24 → 7/31/28
Project: Research project
24-LEUK-25-KO-PMC (KO-MEN-007): Phase 1 Study of Venetoclax/Azacitidine or Venetoclax in Combination with Ziftomenib (KO-539) or Standard Induction Cytarabine/Daunorubicin (7+3) Chemotherapy in Combination with Ziftomenib for the Treatment of Patients wit
Qasrawi, A.
Kura Oncology Incorporated
8/14/24 → 8/14/26
Project: Research project
24-HN-39-GSK (221530): A Randomized, Double-blind, Placebo-controlled Phase 3 Study to evaluate Dostarlimab as Sequential Therapy after Chemoradiation in Participants with Locally Advanced Unresected Head and Neck Squamous Cell Carcinoma
Arnold, S.
PPD Development Inc
8/12/24 → 8/12/26
Project: Research project
NRSA Fellowship for Robyn Allen: A Multispecies System for Elucidating Proliferative Control Mechanisms During Mammalian Skin and Musculoskeletal Regeneration
Seifert, A., Allen, R., Gao, T. & Stromberg, A.
National Institute Arthritis Musculoskeletal & Skin
8/1/24 → 7/31/27
Project: Research project
UK ASCEND (Achieving Success in Community-Engaged research to elimiNate Disparities)
Schoenberg, N., Cassis, L., Evans, N., Hahn, E., Hull, P., Jackson, V., Kern, P., Lauckner, C., Moore, J., Mudd, G., Oser, C., Pearson, K., Staton, C., Stevens-Watkins, D., Surratt, H., Talbert, T., Tannock, L., Thompson, J., Williams, L. & Conwell, D.
National Institute on Minority Health and Health Disparities
7/13/24 → 1/31/29
Project: Research project
Statistical Methods for Identification and Evaluation of Predictive Biomarkers in Cancer
Chen, L., Villano, PhD, J., Wang, C. & Kolesar, J.
National Cancer Institute
7/4/24 → 6/30/26
Project: Research project
FY25 DNA-PK Inhibition in Neuroblastoma
Rellinger, E., Weiss, H. & Rychahou, P.
KY Cabinet for Health and Family Services
7/1/24 → 6/30/26
Project: Research project
FY25 Colon Cancer Screening Services C4833
Knight, J.
KY Cabinet for Health and Family Services
7/1/24 → 6/30/25
Project: Research project
FY25 Defining TP53 Mutations in the Li-Fraumeni Spectrum - Elucidating Specific Effects of TP53 Mutations
D'Orazio, J., Ellingson, S., Shao, Q. & Shelton, B.
KY Cabinet for Health and Family Services
7/1/24 → 6/30/26
Project: Research project
Can We Use Chemotherapy Better in Order to Cure Triple Negative Breast Cancer?
O'Connor, K.
Markey Cancer Center Foundation
7/1/24 → 6/30/25
Project: Research project
CCSG Pilot: The Role of Calpain-5 in Endometrial Cancer
Yang, E., Goellner, E., Piecoro, D. & Wang, C.
National Cancer Institute
7/1/24 → 6/30/25
Project: Research project
FY25 Kentucky Cancer Program East Outreach - Colon Cancer Screening Services C4836
Rogers, M.
KY Cabinet for Health and Family Services
7/1/24 → 6/30/25
Project: Research project
FY25 Breast and/or Cervical Cancer Community Outreach C5249
Rogers, M.
KY Cabinet for Health and Family Services
7/1/24 → 6/30/26
Project: Research project
FY25 Project Inherited Cancer Risk
D'Orazio, J., Allison, D., Badgett, J., Durbin, E. B., Harrington, A., Jeong, J. C., Overley, C., Shelman, N., Weiss, H., Zhang, S., Kolesar, J. & Shaw, A.
KY Cabinet for Health and Family Services
7/1/24 → 6/30/25
Project: Research project
Extracellular vesicle-mediated Nrf2 protein secretion and its therapeutic application in cardiogenic dementia
Tian, C.
7/1/24 → 6/30/27
Project: Research project
The University of Kentucky Racial Equity Initiative Coordinating Center
Stevens-Watkins, D., Adatorwovor, R., Canedo, J., Hargons, C., Knudsen, H., Oser, C., Stoops, W., Vickers-Smith, R., Wolf, B. G. & Francis, D.
National Institute on Drug Abuse
7/1/24 → 6/30/28
Project: Research project
FY25 Lung Cancer Screening KY East Outreach C4857
Rogers, M.
KY Cabinet for Health and Family Services
7/1/24 → 6/30/26
Project: Research project
CCSG Pilot: Targeting Merkel Cell Carcinoma by Natural Product-Based Degraders of MCV Small T Antigen
She, Q., Thorson, J. & Wang, C.
National Cancer Institute
7/1/24 → 6/30/25
Project: Research project
FY25 Macrophage Derived Engineered Vesicles to Treat Pediatric Osteosarcoma
Richards, C. & Badgett, J.
KY Cabinet for Health and Family Services
7/1/24 → 6/30/26
Project: Research project
FY25 Kentucky Cancer Program East Outreach - Colon Cancer Screening Services C4836
Rogers, M.
KY Cabinet for Health and Family Services
7/1/24 → 6/30/25
Project: Research project
FY25 Accelerate C4963
Durbin, E. B., Jeong, J. C. & Wang, C.
KY Cabinet for Health and Family Services
7/1/24 → 6/30/25
Project: Research project
FY25 Spatial Transcriptomic Characterization of Pediatric Brain Tumors in Kentucky
Wang, C., Durbin, E. B., Harrison, D., Jeong, J. C., Liu, J., Neltner, J., Tucker, T., Villano, PhD, J. & Zhang, S.
KY Cabinet for Health and Family Services
7/1/24 → 6/30/25
Project: Research project
FY25 UK/UL Joint Program Inherited Cancer Risk Program
D'Orazio, J., Allison, D., Durbin, E. B., Harrington, A., Jeong, J. C., Shelman, N., Weiss, H. & Zhang, S.
KY Cabinet for Health and Family Services
7/1/24 → 6/30/26
Project: Research project
How Macrophages Regulate Stomach Cancer
Barry-Hundeyin, M.
Markey Cancer Center Foundation
7/1/24 → 6/30/25
Project: Research project
Supplement: Cancer Prevention and Control Programs for State Territorial and Tribal Organizations - NCCCP Supplement Year 3 (carryover funds)
Hull, P. & Tucker, T.
National Center for Chronic Disease Prevention & Healt
6/30/24 → 6/29/27
Project: Research project
24-GI-134-MSD (015-00):A Phase 3, Multicenter, Open-label, Randomized Study to Compare the Efficacy and Safety of MK-2870 Versus Treatment of Physician s Choice in 3L+ Advanced/Metastatic Gastroesophageal Adenocarcinoma (Gastric Adenocarcinoma,Gastroesoph
Patel, R.
Merck Sharp & Dohme Corporation
6/27/24 → 6/27/26
Project: Research project
23-MYEL-21-RG: An Open-Label, Randomized, Phase 3 Study of Linvoseltamab (REGN5458; Anti-BCMA x Anti-CD3 Bispecific Antibody) Vs. The Combination of Elotuzumab, Pomalidomide, and Dexamethasone (EPd), in Patients with Relapsed/Refractory Mulitple Myeloma (
Monohan, G.
Regeneron Pharmaceuticals
6/27/24 → 6/27/26
Project: Research project
24-NHL-37-RG (R1979-ONC-2105): A Phase 3, Open Label, Randomized Study Comparing The Efficacy and Safety of Odronextamab (Regn1979), An Anti-Cd20 ? Anti-Cd3 Bispecific Antibody, in Combination With Chop (O-Chop) Versus Rituximab in Combination With Chop (
Iragavarapu, C.
Regeneron Pharmaceuticals
6/14/24 → 6/14/26
Project: Research project
24-NHL-36-CB-PMC: An Observational Long-term Follow-up Study of Patients Who Received Prior Caribou Cell Therapy (Long term follow-up to NHL 31)
Yalniz, F.
Caribou Biosciences Incorporated
6/3/24 → 6/3/26
Project: Research project
Plk1 in Prostate Cancer Lineage Plasticity
Liu, X. & Liu, J.
Department of Defense
6/1/24 → 5/31/27
Project: Research project
23-GI-133-GI (ML44719): A Phase II, Open-Label, Multi-Cohort, Multicenter Study in Patients With Unresectable Hepatocellular Carcinoma and Child-Pugh B7 and B8 Cirrhosis
Patel, R.
Genentech Inc
5/21/24 → 5/21/26
Project: Research project
GOG-3091: A Two-Arm Randomized, Double-Blind, Placebo-Controlled Phase 2 Selection Trial to Evaluate the Efficacy and Safety of VB10.16 Alone or in Combination with Atezolizumab in Patients with HPV16-Positive, PD-L1-positive, Recurrent or Metastatic Cerv
Miller, R.
Gynecological Oncology Group Foundation Incorporated
5/14/24 → 5/14/26
Project: Research project
23-GI-132-GI (GO44479): A Phase II, Open-Label, Mulitcenter, Randomized Study of The Efficacy and Safety of Adjuvant Autogene Cevumeranplus Atezolizumab and mFOLFIRINOX Vs mFOLFIRINOX Alone in Patients with Resected Pancreatic Ductal Adenocarcinoma
Kim, J.
Genentech Inc
5/14/24 → 5/14/26
Project: Research project
23-LUN-135-EL (J3M-MC-JZQB): A Global Pivotal Study in Participants with KRAS G12C-Mutant, Locally Advanced or Metastatic Non-Small Cell Lung Cancer Comparing First- Line Treatment of LY3537982 and Pembrolizumab vs Placebo and Pembrolizumab in Those with
Arnold, S.
Eli Lilly and Company
5/6/24 → 5/6/26
Project: Research project
Strengthening Kentucky's Art Library Collaborations in Japan- OVPR Curate Program
Hinkle, K.
University of Kentucky’s Office of the Vice President for Research
5/1/24 → 4/30/25
Project: Research project
Mixed Reality in Product Design Education-OVPR Curate Program
Bartlett, K.
University of Kentucky’s Office of the Vice President for Research
5/1/24 → 4/30/25
Project: Research project
Documenting Racial Violence in Kentucky Project: the DRVK Project- OVPR Curate Program
Brown, N.
University of Kentucky’s Office of the Vice President for Research
5/1/24 → 4/30/25
Project: Research project
Still Exploring: “Explore First” Year 2 and First-Generation Intercultural Competence and Career Readiness-OVPR Curate Program
Johnson, K.
University of Kentucky’s Office of the Vice President for Research
5/1/24 → 4/30/25
Project: Research project
Women’s Oral Histories of Arts Administration-OVPR Curate Program
Shane, R.
University of Kentucky’s Office of the Vice President for Research
5/1/24 → 4/30/25
Project: Research project
Remembering and Commemorating the Underground Railroad in Ohio- OVPR Curate Program
Vivian, D.
University of Kentucky’s Office of the Vice President for Research
5/1/24 → 4/30/25
Project: Research project
Identifying and Serving Students Experiencing Homelessness-OVPR Curate Program
Harvey, H.
University of Kentucky’s Office of the Vice President for Research
5/1/24 → 4/30/25
Project: Research project
Joinery & Assembly- OVPR Curate Program
Landsbergis, E.
University of Kentucky’s Office of the Vice President for Research
5/1/24 → 4/30/25
Project: Research project
Industrial Design Education Census (3.0)- OVPR Curate Program
Hagins, C.
University of Kentucky’s Office of the Vice President for Research
5/1/24 → 4/30/25
Project: Research project
Unveiling Legal Anthropological Insights: A Proposal to Review Ithaca College Anthropology Department Archives on Aboriginal Rights Case Mitchell v MNR [2001] 1 S.C.R. 911- OVPR Curate Program
Bergeron, E.
University of Kentucky’s Office of the Vice President for Research
5/1/24 → 4/30/25
Project: Research project
Surveillance, Epidemiology, and End Results (SEER) Program
Durbin, E. B., Huang, B., Shelton, B., Tucker, T. & Ross, F.
National Cancer Institute
5/1/24 → 4/30/25
Project: Research project
NCI Patterns of Care Study: Diagnosis Year 2021 (Prostate Cancer and Ovarian Cancer)
Durbin, E. B.
National Cancer Institute
5/1/24 → 4/30/25
Project: Research project