Saha Cardiovascular Research Center (CVRC)

Research output

Research output per year 1980 2011 2012 2013 2014 2015 2016 2017 2018 2019 2020 2021 2022 2022

• 23272 Citations
• 78 h-index
• 368 Article
• 57 Review article
• 30 Editorial
• 20 Comment/debate
• 37 More
  • 18 Meeting Abstract
  • 8 Letter
  • 6 Short survey
  • 4 Chapter
  • 1 Conference contribution

Research output per year

Research output per year

Search results

• 2022

  Adipocyte-Derived Serum Amyloid A Promotes Angiotensin II-Induced Abdominal Aortic Aneurysms in Obese C57BL/6J Mice

  Shridas, P., Ji, A., Trumbauer, A. C., Noffsinger, V. P., Leung, S. W., Dugan, A. J., Thatcher, S. E., Cassis, L. A., De Beer, F. C., Webb, N. R. & Tannock, L. R., May 1 2022, In: Arteriosclerosis, Thrombosis, and Vascular Biology. 42, 5, p. 632-643 12 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Serum Amyloid A Protein 100%
  • Obese Mice 92%
  • Abdominal Aortic Aneurysm 83%
  • Angiotensin II 73%
  • Adipocytes 72%

• A New Structural Model of Apolipoprotein B100 Based on Computational Modeling and Cross Linking

  Jeiran, K., Gordon, S. M., Sviridov, D. O., Aponte, A. M., Haymond, A., Piszczek, G., Lucero, D., Neufeld, E. B., Vaisman, I. I., Liotta, L., Baranova, A. & Remaley, A. T., Oct 2022, In: International Journal of Molecular Sciences. 23, 19, 11480.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Apolipoproteins 100%
  • Lipoproteins 85%
  • lipoproteins 73%
  • Apolipoprotein B-100 72%
  • Apolipoprotein 61%

• Angiotensinogen Suppression: A New Tool to Treat Cardiovascular and Renal Disease

  Cruz-López, E. O., Ye, D., Wu, C., Lu, H. S., Uijl, E., Colafella, K. M. M. & Jan Danser, A. H., Oct 1 2022, In: Hypertension. 79, 10, p. 2115-2126 12 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Angiotensinogen 100%
  • Renin-Angiotensin System 80%
  • Cardiovascular Diseases 55%
  • Kidney 41%
  • Antisense Oligonucleotides 25%
  2 Scopus citations

• Annexin A1: a promising target for preventing aortic dissections

  Sawada, H., Lu, H. S. & Daugherty, A., May 1 2022, In: Cardiovascular Research. 118, 6, p. 1383-1384 2 p.

  Research output: Contribution to journal › Editorial

  Open Access

  • Annexin A1 100%
  • Dissecting Aneurysm 75%

• A sensitive and adaptable method to measure platelet-fibrin clot contraction kinetics

  Prakhya, K. S., Luo, Y., Adkins, J., Hu, X., Wang, Q. J. & Whiteheart, S., Jul 1 2022, In: Research and Practice in Thrombosis and Haemostasis. 6, 5

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Fibrin 100%
  • Blood Platelets 76%
  • Kinetics 70%
  • Fibrinogen 46%
  • blebbistatin 40%

• A sensitive and adaptable method to measure platelet-fibrin clot contraction kinetics

  Prakhya, K. S., Luo, Y., Adkins, J., Hu, X., Wang, Q. J. & Whiteheart, S. W., Jul 2022, In: Research and Practice in Thrombosis and Haemostasis. 6, 5, e12755.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Fibrin 100%
  • Blood Platelets 76%
  • Kinetics 70%
  • Fibrinogen 46%
  • blebbistatin 40%

• ASK1 Regulates Bleomycin-induced Pulmonary Fibrosis

  Valenca, S. S., Dong, B. E., Gordon, E. M., Sun, R. C. & Waters, C. M., May 2022, In: American Journal of Respiratory Cell and Molecular Biology. 66, 5, p. 484-496 13 p.

  Research output: Contribution to journal › Article › peer-review

  • Redox Indicator 100%
  • Pulmonary Fibrosis 76%
  • Bleomycin 75%
  • Inhibition of Apoptosis 61%
  • Phosphotransferases 51%
  3 Scopus citations

• COMManding platelet α-granule cargo

  Lykins, J. T. & Whiteheart, S. W., Feb 10 2022, In: Blood. 139, 6, p. 809-811 3 p.

  Research output: Contribution to journal › Editorial

  Open Access

  • Blood Platelets 100%

• Conventional Vasopressor andVasopressor-SparingStrategies toCounteract the Blood Pressure–LoweringEffect of Small Interfering RNA TargetingAngiotensinogen

  Uijl, E., Ye, D., Ren, L., Mirabito Colafella, K. M., van Veghel, R., Garrelds, I. M., Lu, H. S., Daugherty, A., Hoorn, E. J., Nioi, P., Foster, D. & Jan Danser, A. H., Aug 2 2022, In: Journal of the American Heart Association. 11, 15, e026426.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Angiotensinogen 100%
  • Fludrocortisone 74%
  • Small Interfering RNA 72%
  • Midodrine 31%
  • Liver 19%
  3 Scopus citations

• Design and rationale for the supermarket and web-based intervention targeting nutrition (SuperWIN) for cardiovascular risk reduction trial

  Couch, S. C., Helsley, R. N., Siegel, F. U., Saelens, B. E., Magazine, M., Eckman, M. H., Summer, S., Fenchel, M., King, E. C., Bhatt, D. L. & Steen, D. L., Jun 2022, In: American Heart Journal. 248, p. 21-34

  Research output: Contribution to journal › Article › peer-review

  • Internet-Based Intervention 100%
  • Risk Reduction Behavior 76%
  1 Scopus citations

• Dysregulation of Protein S in COVID-19

  Sim, M. M. S. & Wood, J. P., 2022, (Accepted/In press) In: Best Practice and Research in Clinical Haematology. 101376.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Acquired Protein S Deficiency 100%
  • Coronavirus 88%
  • Protein S 87%
  • Blood Proteins 31%
  • Protein 29%

• Edaravone Attenuated Angiotensin II-Induced Atherosclerosis and Abdominal Aortic Aneurysms in Apolipoprotein E-Deficient Mice

  Uchida, H. A., Takatsuka, T., Hada, Y., Umebayashi, R., Takeuchi, H., Shikata, K., Subramanian, V., Daugherty, A. & Wada, J., Aug 2022, In: Biomolecules. 12, 8, 1117.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Edaravone 100%
  • Angiotensin 71%
  • Apolipoprotein 68%
  • Abdominal Aortic Aneurysm 62%
  • Apolipoproteins E 59%
  1 Scopus citations

• Editorial: Cardiovascular Fibrosis and Related Diseases: Basic and Clinical Research Advances

  Bei, Y., Lu, H. S. & Zhong, J., Mar 24 2022, In: Frontiers in Cardiovascular Medicine. 9, 879780.

  Research output: Contribution to journal › Editorial

  Open Access

  • Fibrosis 100%
  1 Scopus citations

• Embryonic Heterogeneity of Smooth Muscle Cells in the Complex Mechanisms of Thoracic Aortic Aneurysms

  Ito, S., Lu, H. S., Daugherty, A. & Sawada, H., Sep 2022, In: Genes. 13, 9, 1618.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Thoracic Aortic Aneurysm 100%
  • Smooth Muscle Myocytes 67%
  • Neural Crest 22%
  • Cell Wall 19%
  • Thoracic Aorta 19%

• Expression of a PCSK9 Gain-of-Function Mutation in C57BL/6J Mice to Facilitate Angiotensin II-Induced AAAs

  Sawada, H., Daugherty, A. & Lu, H. S., Jul 2022, In: Biomolecules. 12, 7, 915.

  Research output: Contribution to journal › Comment/debate

  Open Access

  • Proprotein Convertase 9 100%
  • Gain of Function Mutation 89%
  • Angiotensin 86%
  • Low-Density Lipoprotein 79%
  • Hypercholesterolemic 75%
  1 Scopus citations

• Extracellular Histones Trigger Disseminated Intravascular Coagulation by Lytic Cell Death

  Zhang, Y., Wu, C., Li, L., Pandeya, A., Zhang, G., Cui, J., Kirchhofer, D., Wood, J. P., Smyth, S. S., Wei, Y. & Li, Z., Jun 1 2022, In: International Journal of Molecular Sciences. 23, 12, 6800.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Cell death 100%
  • Coagulation 89%
  • Disseminated Intravascular Coagulation 79%
  • death 76%
  • coagulation 76%
  1 Scopus citations

• Fludrocortisone Induces Aortic Pathologies in Mice

  Ye, D., Wu, C., Chen, H., Liang, C. L., Howatt, D. A., Franklin, M. K., Moorleghen, J. J., Tyagi, S. C., Uijl, E., Jan Danser, A. H., Sawada, H., Daugherty, A. & Lu, H. S., Jun 2022, In: Biomolecules. 12, 6, 825.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Fludrocortisone 100%
  • Pathology 31%
  • Blood Pressure 23%
  • Western Diet 12%
  • Thoracic Aorta 12%
  1 Scopus citations

• Gut microbe-targeted choline trimethylamine lyase inhibition improves obesity via rewiring of host circadian rhythms

  Schugar, R. C., Gliniak, C. M., Osborn, L. J., Massey, W., Sangwan, N., Horak, A., Banerjee, R., Orabi, D., Helsley, R. N., Brown, A. L., Burrows, A., Finney, C., Fung, K. K., Allen, F. M., Ferguson, D., Gromovsky, A. D., Neumann, C., Cook, K., McMillan, A., Buffa, J. A., & 13 othersAnderson, J. T., Mehrabian, M., Goudarzi, M., Willard, B., Mak, T. D., Armstrong, A. R., Swanson, G., Keshavarzian, A., Garcia-Garcia, J. C., Wang, Z., Lusis, A. J., Hazen, S. L. & Brown, J. M., Jan 24 2022, In: eLife. 11

  Research output: Contribution to journal › Article › peer-review

  • trimethylamine 100%
  • Lyases 90%
  • Trimethylamine 76%
  • Choline 68%
  • Circadian Rhythm 66%
  11 Scopus citations

• Gut microbial trimethylamine is elevated in alcohol-associated hepatitis and contributes to ethanol-induced liver injury in mice

  Helsley, R. N., Miyata, T., Kadam, A., Varadharajan, V., Sangwan, N., Huang, E. C., Banerjee, R., Brown, A. L., Fung, K. K., Massey, W. J., Neumann, C., Orabi, D., Osborn, L. J., Schugar, R. C., McMullen, M. R., Bellar, A., Poulsen, K. L., Kim, A., Pathak, V., Mrdjen, M., & 16 othersAnderson, J. T., Willard, B., McClain, C. J., Mitchell, M., McCullough, A. J., Radaeva, S., Barton, B., Szabo, G., Dasarathy, S., Garcia-Garcia, J. C., Rotroff, D. M., Allende, D. S., Wang, Z., Hazen, S. L., Nagy, L. E. & Brown, J. M., Jan 27 2022, In: eLife. 11

  Research output: Contribution to journal › Article › peer-review

  • trimethylamine 100%
  • Trimethylamine 76%
  • Hepatitis 59%
  • Ethanol 53%
  • Alcohols 47%
  6 Scopus citations

• Identifying novel mechanisms of abdominal aortic aneurysm via unbiased proteomics and systems biology

  Morgan, S., Lee, L. H., Halu, A., Nicolau, J. S., Higashi, H., Ha, A. H., Wen, J. R., Daugherty, A., Libby, P., Cameron, S. J., Mix, D., Aikawa, E., Owens, A. P., Singh, S. A. & Aikawa, M., Aug 3 2022, In: Frontiers in Cardiovascular Medicine. 9, 889994.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Systems Biology 100%
  • Abdominal Aortic Aneurysm 92%
  • Proteomics 76%
  • Aneurysm 49%
  • Pancreatic Elastase 21%

• Imaging Techniques for Aortic Aneurysms and Dissections in Mice: Comparisons of Ex Vivo, In Situ, and Ultrasound Approaches

  Ito, S., Lu, H. S., Daugherty, A. & Sawada, H., Feb 2022, In: Biomolecules. 12, 2, 339.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Lethal 100%
  • Aortic Aneurysm 96%
  • Dissecting Aneurysm 93%
  • Dimension 62%
  • Aorta 14%
  3 Scopus citations

• Inhibition of the Renin-Angiotensin System Fails to Suppress β-Aminopropionitrile-Induced Thoracic Aortopathy in Mice - Brief Report

  Sawada, H., Ohno-Urabe, S., Ye, D., Franklin, M. K., Moorleghen, J. J., Howatt, D. A., Mullick, A. E., Daugherty, A. & Lu, H. S., Oct 1 2022, In: Arteriosclerosis, Thrombosis, and Vascular Biology. 42, 10, p. 1254-1261 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Aminopropionitrile 100%
  • Renin-Angiotensin System 63%
  • Thorax 42%
  • Aortic Rupture 23%
  • Angiotensin Type 1 Receptor 22%

• Iron Deficiency Induces Heart Failure with Ectopic Cardiac Calcification in Mice with Metabolic Syndrome

  Naito, Y., Sawada, H., Yasumura, S., Horimatsu, T., Okuno, K., Tahara, S., Nishimura, K., Asakura, M., Tsujino, T., Masuyama, T. & Ishihara, M., Jul 1 2022, In: Circulation: Heart Failure. 15, 7, p. e009034

  Research output: Contribution to journal › Article › peer-review

  • Metabolic Syndrome 100%
  • Iron 90%
  • Heart Failure 79%

• Key Factors for Improving Rigor and Reproducibility: Guidelines, Peer Reviews, and Journal Technical Reviews

  Lu, H. S. & Daugherty, A., Mar 9 2022, In: Frontiers in Cardiovascular Medicine. 9, 856102.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Peer Review 100%
  • Guidelines 51%
  • Arteriosclerosis 32%
  • American Heart Association 26%
  • Checklist 26%

• Management of Dyslipidemia in Endocrine Diseases

  Tannock, L. R., Sep 2022, In: Endocrinology and Metabolism Clinics of North America. 51, 3, p. 589-602 14 p.

  Research output: Contribution to journal › Review article › peer-review

  • Endocrine System Diseases 100%
  • Dyslipidemias 73%

• Perspectives on Cognitive Phenotypes and Models of Vascular Disease

  Muratoglu, S. C., Charette, M. F., Galis, Z. S., Greenstein, A. S., Daugherty, A., Joutel, A., Kozel, B. A., Wilcock, D. M., Collins, E. C., Sorond, F. A., Howell, G. R., Hyacinth, H. I., Lloyd, K. K. C., Stenmark, K. R., Boehm, M., Kahn, M. L., Corriveau, R., Wells, S., Bussey, T. J., Sukoff Rizzo, S. J., & 1 othersIruela-Arispe, M. L., Jul 1 2022, In: Arteriosclerosis, Thrombosis, and Vascular Biology. 42, 7, p. 831-838 8 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Vascular Diseases 100%
  • Phenotype 61%
  • Blood Vessels 60%
  • National Heart, Lung, and Blood Institute (U.S.) 35%
  • Vascular Dementia 31%
  1 Scopus citations

• Platelet-HIV: interactions and their implications

  Whiteheart, S. W., 2022, In: Platelets. 33, 2, p. 208-211 4 p.

  Research output: Contribution to journal › Article › peer-review

  • Blood Platelets 100%
  • HIV 88%
  • Viremia 48%
  • Acquired Immunodeficiency Syndrome 35%
  • Viruses 28%

• Rats with high aerobic capacity display enhanced transcriptional adaptability and upregulation of bile acid metabolism in response to an acute high-fat diet

  Stierwalt, H. D., Morris, E. M., Maurer, A., Apte, U., Phillips, K., Li, T., Meers, G. M. E., Koch, L. G., Britton, S. L., Graf, G., Rector, R. S., Mercer, K., Shankar, K. & Thyfault, J. P., Aug 2022, In: Physiological Reports. 10, 15, e15405.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Bile Acids and Salts 100%
  • High Fat Diet 96%
  • Up-Regulation 69%
  • Sucrose 35%
  • Liver 31%

• Recipients of the 2022 Early Career Investigator Awards

  Daugherty, A., May 1 2022, In: Arteriosclerosis, Thrombosis, and Vascular Biology. 42, 5, p. 515 1 p.

  Research output: Contribution to journal › Comment/debate

  Open Access

  • Research Personnel 100%

• Replenishing HDL with synthetic HDL has multiple protective effects against sepsis in mice

  Guo, L., Morin, E. E., Yu, M., Mei, L., Fawaz, M. V., Wang, Q., Yuan, Y., Zhan, C. G., Standiford, T. J., Schwendeman, A. & Li, X. A., Mar 15 2022, In: Science Signaling. 15, 725, eabl9322.

  Research output: Contribution to journal › Article › peer-review

  • High-Density Lipoprotein Cholesterol 100%
  • Protective 52%
  • Sepsis 51%
  • HDL Cholesterol 34%
  • ETC 642 29%
  2 Scopus citations

• Role of sympathetic pathway in light-phase time-restricted feeding-induced blood pressure circadian rhythm alteration

  Hou, T., Chacon, A. N., Su, W., Katsumata, Y., Guo, Z. & Gong, M. C., Sep 8 2022, In: Frontiers in Nutrition. 9, 969345.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • restricted feeding 100%
  • Circadian Rhythm 88%
  • circadian rhythm 83%
  • blood pressure 82%
  • Fasting 67%

• Second Heart Field-Derived Cells Contribute to Angiotensin II-Mediated Ascending Aortopathies

  Sawada, H., Katsumata, Y., Higashi, H., Zhang, C., Li, Y., Morgan, S., Lee, L. H., Singh, S. A., Chen, J. Z., Franklin, M. K., Moorleghen, J. J., Howatt, D. A., Rateri, D. L., Shen, Y. H., Lemaire, S. A., Aikawa, M., Majesky, M. W., Lu, H. S. & Daugherty, A., Mar 29 2022, In: Circulation. 145, 13, p. 987-1001 15 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Angiotensin II 100%
  • Heart 67%
  • Aorta 40%
  • Adventitia 34%
  • Pathology 29%
  6 Scopus citations

• Serum Amyloid A is not obligatory for high-fat, high-sucrose, cholesterol-fed diet-induced obesity and its metabolic and inflammatory complications

  Ji, A., Trumbauer, A. C., Noffsinger, V. P., Jeon, H., Patrick, A. C., De Beer, F. C., Webb, N. R., Tannock, L. R. & Shridas, P., Apr 2022, In: PLoS ONE. 17, 4 April, e0266688.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Serum Amyloid A Protein 100%
  • Sucrose 74%
  • Fats 56%
  • Cholesterol 55%
  • Obesity 52%
  2 Scopus citations

• Simple, accurate calculation of mechanical power in pressure controlled ventilation (PCV)

  Trinkle, C. A., Broaddus, R. N., Sturgill, J. L., Waters, C. M. & Morris, P. E., Dec 2022, In: Intensive Care Medicine Experimental. 10, 1, 22.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Ventilation 100%
  • Pressure 73%
  • Mechanical Ventilators 71%
  • Energy Transfer 29%

• Single-Cell Analysis of Aneurysmal Aortic Tissue in Patients with Marfan Syndrome Reveals Dysfunctional TGF-β Signaling

  Dawson, A., Li, Y., Li, Y., Ren, P., Vasquez, H. G., Zhang, C., Rebello, K. R., Ageedi, W., Azares, A. R., Mattar, A. B., Sheppard, M. B., Lu, H. S., Coselli, J. S., Cassis, L. A., Daugherty, A., Shen, Y. H. & Lemaire, S. A., Jan 2022, In: Genes. 13, 1, 95.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Single-Cell Analysis 100%
  • Marfan Syndrome 95%
  • Smooth Muscle Myocytes 49%
  • Fibroblasts 27%
  • Aortic Aneurysm 21%
  8 Scopus citations

• Sports Participation and Physical Activity in Individuals with Heritable Thoracic Aortic Disease and Aortopathy Conditions

  Sheppard, M. B. & Braverman, A. C., Jul 2022, In: Clinics in Sports Medicine. 41, 3, p. 511-527 17 p.

  Research output: Contribution to journal › Review article

  • Thoracic Diseases 100%
  • Aortic Diseases 85%
  • Sports 60%
  • Exercise 44%
  • Shared Decision Making 21%

• The HDL Proteome Watch: Compilation of studies leads to new insights on HDL function

  Davidson, W. S., Shah, A. S., Sexmith, H. & Gordon, S. M., Feb 2022, In: Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids. 1867, 2, 159072.

  Research output: Contribution to journal › Review article › peer-review

  • HDL Lipoproteins 100%
  • Proteome 98%
  • Proteins 21%
  • Complement System Proteins 14%
  • Hemostasis 11%
  12 Scopus citations

• Tissue factor release following traumatic brain injury drives thrombin generation

  Hubbard, W. B., Sim, M. M. S., Saatman, K. E., Sullivan, P. G. & Wood, J. P., May 2022, In: Research and Practice in Thrombosis and Haemostasis. 6, 4, e12734.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Thromboplastin 100%
  • Thrombin 89%
  • Traumatic Brain Injury 88%
  • Closed Head Injuries 40%
  • Extracellular Vesicles 35%

• Total Plasma Protein S Is a Prothrombotic Marker in People Living with HIV

  Sim, M. M. S., Banerjee, M., Myint, T., Garvy, B. A., Whiteheart, S. W. & Wood, J. P., Aug 1 2022, In: Journal of Acquired Immune Deficiency Syndromes. 90, 4, p. 463-471 9 p.

  Research output: Contribution to journal › Article › peer-review

  • Protein S 100%
  • Blood Proteins 71%
  • Thrombin 69%
  • HIV-1 61%
  • HIV 55%
  1 Scopus citations

• Twenty Years of Studying AngII (Angiotensin II)-Induced Abdominal Aortic Pathologies in Mice: Continuing Questions and Challenges to Provide Insight into the Human Disease

  Sawada, H., Lu, H. S., Cassis, L. A. & Daugherty, A., Mar 1 2022, In: Arteriosclerosis, Thrombosis, and Vascular Biology. 42, 3, p. 277-288 12 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Abdominal Aortic Aneurysm 100%
  • Angiotensin II 87%
  • Pathology 57%
  • Publications 18%
  • Animal Models 16%
  8 Scopus citations

• VAMP3 and VAMP8 Regulate the Development and Functionality of Parasitophorous Vacuoles Housing Leishmania amazonensis

  Séguin, O., Mai, L. T., Ospina, H. A., Guay-Vincent, M. M., Whiteheart, S. W., Stäger, S. & Descoteaux, A., Mar 2022, In: Infection and Immunity. 90, 3, e00183-21.

  Research output: Contribution to journal › Article › peer-review

  • Vesicle-Associated Membrane Protein 3 100%
  • Leishmania amazonensis 82%
  • Leishmania 66%
  • Vacuoles 60%
  • vacuoles 51%
  2 Scopus citations

• Web of Science's Citation Median Metrics Overcome the Major Constraints of the Journal Impact Factor

  Daugherty, A., Hegele, R. A., Lu, H. S., MacKman, N., Rader, D. J. & Weber, C., Apr 1 2022, In: Arteriosclerosis, Thrombosis, and Vascular Biology. 42, 4, p. 367-371 5 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Journal Impact Factor 100%
  • Publications 9%

• β-Aminopropionitrile-induced aortic aneurysm and dissection in mice

  Sawada, H., Beckner, Z. A., Ito, S., Daugherty, A. & Lu, H. S., Jan 2022, In: JVS-Vascular Science. 3, p. 64-72 9 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Aminopropionitrile 100%
  • Aortic Aneurysm 70%
  • Dissecting Aneurysm 67%
  • Drug Development 19%
  • Research Design 16%
  3 Scopus citations
• 2021

  Addressing Kentucky's Physician Shortage while Securing a Network for a Research-Intensive, Referral Academic Medical Center: Where Public Policy Meets Effective Clinical Strategic Planning

  Griffith, C. H., De Beer, F., Edwards, R. L., Smith, C., Colvin, G. & Karpf, M., Mar 1 2021, In: Academic Medicine. p. 375-380 6 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • strategic planning 100%
  • shortage 85%
  • physician 71%
  • public policy 70%
  • medicine 56%

• Age and sex are associated with the plasma lipidome: findings from the GOLDN study

  Slade, E., Irvin, M. R., Xie, K., Arnett, D. K., Claas, S. A., Kind, T., Fardo, D. W. & Graf, G. A., Dec 2021, In: Lipids in Health and Disease. 20, 1, 30.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Antilipemic Agent 100%
  • Lipidomics 87%
  • Lipid 44%
  • Diet 44%
  • Lipids 42%
  10 Scopus citations

• A luminescence-based protocol for assessing fructose metabolism via quantification of ketohexokinase enzymatic activity in mouse or human hepatocytes

  Park, S-H., Helsley, R. N., Noetzli, L., Tu, H-C., Wallenius, K., O'Mahony, G., Boucher, J., Liu, J. & Softic, S., Sep 17 2021, In: STAR Protocols. 2, 3, p. 100731

  Research output: Contribution to journal › Article › peer-review

  • ketohexokinase 100%
  • Fructose 60%
  • Luminescence 59%
  • Hepatocytes 44%
  • Enzyme Activity 43%
  1 Scopus citations

• Authentication of in situ measurements for thoracic aortic aneurysms in mice

  Ohno-Urabe, S., Kukida, M., Franklin, M. K., Katsumata, Y., Su, W., Gong, M. C., Lu, H. S., Daugherty, A. & Sawada, H., 2021, (Accepted/In press) In: Arteriosclerosis, Thrombosis, and Vascular Biology. p. 2117-2119 3 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Thoracic Aortic Aneurysm 100%
  6 Scopus citations

• Deletion of AT1a (Angiotensin II Type 1a) Receptor or Inhibition of Angiotensinogen Synthesis Attenuates Thoracic Aortopathies in Fibrillin1^C1041G/+Mice

  Chen, J. Z., Sawada, H., Ye, D., Katsumata, Y., Kukida, M., Ohno-Urabe, S., Moorleghen, J. J., Franklin, M. K., Howatt, D. A., Sheppard, M. B., Mullick, A. E., Lu, H. S. & Daugherty, A., 2021, (Accepted/In press) In: Arteriosclerosis, Thrombosis, and Vascular Biology. p. 2538-2550 13 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Angiotensinogen 100%
  • Angiotensin Type 1 Receptor 95%
  • Thorax 53%
  • Thoracic Aortic Aneurysm 50%
  • Dilatation 32%
  5 Scopus citations

• Dietary and Pharmacologic Manipulations of Host Lipids and Their Interaction With the Gut Microbiome in Non-human Primates

  Lang, J. M., Sedgeman, L. R., Cai, L., Layne, J. D., Wang, Z., Pan, C., Lee, R., Temel, R. E. & Lusis, A. J., Aug 26 2021, In: Frontiers in Medicine. 8, 646710.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Gastrointestinal Microbiome 100%
  • Primates 94%
  • Microbiota 85%
  • Liver X Receptors 79%
  • Bile Acids and Salts 75%
  1 Scopus citations

• Discussion of talks from the symposium: Factor X: From thrombokinase to oral anti-coagulants and beyond

  Milstone, L. M., Jackson, C., Becker, R. C., Camire, R., Knabb, R., Mann, K., Ruf, W., Wexler, R. R. & Wood, J., Aug 2021, In: Journal of Thrombosis and Thrombolysis. 52, 2, p. 408-413 6 p.

  Research output: Contribution to journal › Letter › peer-review

  Open Access

  • Factor X 100%
  • Coagulants 98%
  • Factor Xa 96%