Surgery

Active

A Randomized, Double Blinded Controlled Parallel Group Non-inferiority, Phase III Study to Evaluate the Efficacy and Safety of the INTERCEPT Blood System for Red Blood Cells in Patients undergoing Complex Cardiac Surgery Procedures (ReCePI)

Sekela, M. (PI)

Cerus Corporation

5/24/19 → 8/3/25

Project: Research project

Impact of Envarsus XR on Kidney Biopsy Subclinical Rejection and Blood Immunologic Profile

Gedaly, R. (PI), Marti, F. (CoI), Rendulic, T. (CoI) & Berger, J. (Former CoI)

Veloxis Pharmaceuticals Incorporated

11/6/17 → 2/7/26

Project: Research project

Surgical Timing and Rehabilitation (STaR) for Multiple Ligament Knee Injuries (MLKs): A Multicenter Integrated Clinical Trial

Johnson, D. (PI), Conley, C. (CoI) & JACOBS, C. (Former CoI)

University of Pittsburgh

9/30/17 → 9/29/25

Project: Research project

Annual Start-Up: Surgical Timing and Rehabilitation (STaR) for Multiple Ligament Knee Injuries (MLKs): A Multicenter Integrated Clinical Trial

Johnson, D. (PI), Conley, C. (CoI) & JACOBS, C. (Former CoI)

University of Pittsburgh

9/30/17 → 9/29/25

Project: Research project

University of Kentucky Center for Cancer Metabolism (Project 4)

Rellinger, E. (PI), Moseley, H. (CoI) & Wang, C. (CoI)

National Institute of General Medical Sciences

3/1/17 → 12/31/26

Project: Research project

University of Kentucky Center for Cancer Metabolism (Admin Core)

Zhou, B. (PI), Brainson, C. (CoI), Chaiswing, L. (CoI), D'Orazio, J. (CoI), Duncan, E. (CoI), Fan, W.-M. (CoI), Fong, K. W. (CoI), Hao, Z. (CoI), Higashi, R. (CoI), Jia, J. (CoI), Lane, A. (CoI), Liu, J. (CoI), Liu, X. (CoI), Moseley, H. (CoI), Myint, Z. (CoI), Rellinger, E. (CoI), Thorson, J. (CoI), Van Eldik, L. (CoI), Vanderford, N. (CoI), Wang, C. (CoI), Weiss, H. (CoI) & Yalniz, F. (CoI)

National Institute of General Medical Sciences

3/1/17 → 12/31/26

Project: Research project

Mechanisms Regulating Neurotensin Secretion and Function

Evers, B. M. (PI), Cassis, L. (CoI), Fan, W.-M. (CoI), Hinds, T. (CoI), Jia, J. (CoI), Lee, E. (CoI), Li, J. (CoI), Moseley, H. (CoI), Starr, M. (CoI) & Weiss, H. (CoI)

National Institute Diabetes & Digestive & Kidney

2/1/17 → 6/30/26

Project: Research project

Kentucky Center for Clinical and Translational Science - Institutional Career Development Core

Kelly, T. (PI), Barry-Hundeyin, M. (CoI), Curry, T. (CoI), DiPaola, R. (CoI), Evers, B. M. (CoI), Giannone, P. (CoI), Guy, R. K. (CoI), Helmy, Y. A. (CoI), Jicha, G. (CoI), Kern, P. (CoI), King, V. (CoI), Lephart, S. (CoI), Liu, J. (CoI), Talbert, J. (CoI), Trout, A. (CoI), Williams, L. (CoI), Bush, M. (CoPI), Arnett, D. (Former CoI), Duncan, M. (Former CoI), Heath, E. (Former CoI), Lacy Leigh, M. (Former CoI), McLouth, L. (Former CoI), Roberts, J. (Former CoI), Samaan, M. (Former CoI) & Supinski, G. (Former CoI)

National Center for Advancing Translational Sciences

8/15/16 → 6/30/26

Project: Research project

Carotid Revascularization and Medical Management for Asymptomatic Carotid Stenosis Trial (CREST-2) Protocol

Lee, J. (PI), Endean, E. (CoI), Fraser, J. (CoI) & Pettigrew, L. (Former PI)

Mayo Clinic

3/15/14 → 8/31/25

Project: Research project

University of Kentucky Markey Cancer Center - Cancer Center Support Grant (Clinical Protocol and Data Management (CPMD))

Evers, B. M. (PI), Adams, V. (CoI), Allison, D. (CoI), Anthony, L. (CoI), Arnold, S. (CoI), Bocklage, T. (CoI), Burris, J. (CoI), Butterfield, D. A. (CoI), Chen, L. (CoI), COHEN, D. (CoI), Durbin, E. B. (CoI), Ellingson, S. (CoI), Gao, T. (CoI), Hands, I. (CoI), Higashi, R. (CoI), Huang, B. (CoI), Hull, P. (CoI), Jeong, J. C. (CoI), Kavuluru, R. (CoI), Kuhs, K. (CoI), Kunos, C. (CoI), Lee, E. (CoI), Liu, J. (CoI), McGarry, R. (CoI), Moseley, H. (CoI), Mullett, T. (CoI), O'Connor, K. (CoI), Patel, R. (CoI), Plattner, R. (CoI), Rogers, J. (CoI), Shelton, B. (CoI), St Clair, D. (CoI), Stanley, S. (CoI), Stapleton, J. (CoI), Sturgill, J. (CoI), Vanderford, N. (CoI), Villano, PhD, J. (CoI), Wang, C. (CoI), Wei, S. (CoI), Weiss, H. (CoI), Williams, L. (CoI), Woodward, J. (CoI), Yan, D. (CoI), Zhang, S. (CoI), Zhou, B. (CoI) & Kolesar, J. (Former CoI)

National Cancer Institute

7/8/13 → 6/30/28

Project: Research project

University of Kentucky Markey Cancer Center - Cancer Center Support Grant (Community Outreach and Engagement (COE))

Evers, B. M. (PI), Adams, V. (CoI), Allison, D. (CoI), Anthony, L. (CoI), Arnold, S. (CoI), Bocklage, T. (CoI), Burris, J. (CoI), Butterfield, D. A. (CoI), Chen, L. (CoI), COHEN, D. (CoI), Durbin, E. B. (CoI), Ellingson, S. (CoI), Gao, T. (CoI), Hands, I. (CoI), Higashi, R. (CoI), Huang, B. (CoI), Hull, P. (CoI), Jeong, J. C. (CoI), Kavuluru, R. (CoI), Kuhs, K. (CoI), Kunos, C. (CoI), Lee, E. (CoI), Liu, J. (CoI), McGarry, R. (CoI), Moseley, H. (CoI), Mullett, T. (CoI), O'Connor, K. (CoI), Patel, R. (CoI), Plattner, R. (CoI), Rogers, J. (CoI), Shelton, B. (CoI), St Clair, D. (CoI), Stanley, S. (CoI), Stapleton, J. (CoI), Sturgill, J. (CoI), Vanderford, N. (CoI), Villano, PhD, J. (CoI), Wang, C. (CoI), Wei, S. (CoI), Weiss, H. (CoI), Williams, L. (CoI), Woodward, J. (CoI), Yan, D. (CoI), Zhang, S. (CoI), Zhou, B. (CoI) & Kolesar, J. (Former CoI)

National Cancer Institute

7/8/13 → 6/30/28

Project: Research project

University of Kentucky Markey Cancer Center - Cancer Center Support Grant (Prime)

Evers, B. M. (PI), Adams, V. (CoI), Allison, D. (CoI), Anthony, L. (CoI), Arnold, S. (CoI), Bocklage, T. (CoI), Brainson, C. (CoI), Burris, J. (CoI), Burrows Franco, A. (CoI), Butterfield, D. A. (CoI), Chen, L. (CoI), Durbin, E. B. (CoI), Ellingson, S. (CoI), Gandhapudi, S. (CoI), Gao, T. (CoI), Hands, I. (CoI), Hao, Z. (CoI), Higashi, R. (CoI), Huang, B. (CoI), Hull, P. (CoI), Jeong, J. C. (CoI), Kavuluru, R. (CoI), Kuhs, K. (CoI), Lee, E. (CoI), Liu, J. (CoI), McGarry, R. (CoI), McLouth, L. (CoI), Moseley, H. (CoI), Mullett, T. (CoI), O'Connor, K. (CoI), Patel, R. (CoI), Plattner, R. (CoI), Rogers, J. (CoI), Shelton, B. (CoI), St Clair, D. (CoI), Sturgill, J. (CoI), Vanderford, N. (CoI), Villano, PhD, J. (CoI), Wang, C. (CoI), Wei, S. (CoI), Weiss, H. (CoI), Williams, L. (CoI), Yan, D. (CoI), Zhang, S. (CoI), Zhou, B. (CoI), COHEN, D. (Former CoI), Kolesar, J. (Former CoI), Kunos, C. (Former CoI), Stanley, S. (Former CoI), Stapleton, J. (Former CoI) & Woodward, J. (Former CoI)

National Cancer Institute

7/8/13 → 6/30/28

Project: Research project

University of Kentucky Markey Cancer Center - Cancer Center Support Grant (Plan to Enhance Diversity (PED))

Evers, B. M. (PI), Adams, V. (CoI), Allison, D. (CoI), Anthony, L. (CoI), Arnold, S. (CoI), Bocklage, T. (CoI), Burris, J. (CoI), Butterfield, D. A. (CoI), Chen, L. (CoI), COHEN, D. (CoI), Durbin, E. B. (CoI), Ellingson, S. (CoI), Gao, T. (CoI), Hands, I. (CoI), Higashi, R. (CoI), Huang, B. (CoI), Hull, P. (CoI), Jeong, J. C. (CoI), Kavuluru, R. (CoI), Kuhs, K. (CoI), Kunos, C. (CoI), Lee, E. (CoI), Liu, J. (CoI), McGarry, R. (CoI), Moseley, H. (CoI), Mullett, T. (CoI), O'Connor, K. (CoI), Patel, R. (CoI), Plattner, R. (CoI), Rogers, J. (CoI), Shelton, B. (CoI), St Clair, D. (CoI), Stanley, S. (CoI), Stapleton, J. (CoI), Sturgill, J. (CoI), Vanderford, N. (CoI), Villano, PhD, J. (CoI), Wang, C. (CoI), Wei, S. (CoI), Weiss, H. (CoI), Williams, L. (CoI), Woodward, J. (CoI), Yan, D. (CoI), Zhang, S. (CoI), Zhou, B. (CoI) & Kolesar, J. (Former CoI)

National Cancer Institute

7/8/13 → 6/30/28

Project: Research project

A Multi-Center Retrospective Study of AdvancTM Nerve Graft Utilization, Evaluations, and Outcomes in Peripheral Nerve Injury Repair (RANGER)

Brgoch, M. (PI), Bourne, D. (Former PI), Duggal, A. (Former PI) & Rinker, B. (Former PI)

AxoGen Incorporated

3/18/10 → 6/12/25

Project: Research project

Not started

An Open-Label Randomized, Multicenter, Phase IIIB Study To Assess the Efficacy, Safety, and Tolerance of Beriplex P/N Compared with Plasma for the Rapid Reversal of Coagulopathy Induced by Coumadin Derivatives in Subjects Requiring Emergency Surgery or Invasive Intervention.

Saha, S. (PI)

Project: Research project

Pneumonectomy for Lung Cancer: An outcomes analysis of 100 Consecutive cases

Saha, S. (PI)

Project: Research project

Development of a Percutaneous Double Lumen Cannula- Based Cavopulmonary Assist System Toward Clinical Application

Ballard Croft, C. (PI)

Project: Research project

Finished

STTR: An Interactive Emergency Tourniquet

Levy, B. (PI), Castle, J. (CoI) & Warriner, Z. (CoI)

XLerate Health LLC

10/1/24 → 2/28/25

Project: Research project

CCSG Pilot: Sociological Barriers and Facilitators to Lung Cancer Screening Among Black Adults Who Use Various Combustible Tobacco Products: Assessing the Equity Impact of the USPSTF Lung Cancer Screening Recommendations

Mattingly, D. (PI), Burris, J. (CoI), Conwell, D. (CoI), Moore, J. (CoI) & Mullett, T. (CoI)

National Cancer Institute

4/1/24 → 3/31/25

Project: Research project

A Phase 2, Observer-Blind, Placebo-Controlled, Proof-of-concept Trial to Evaluate the Efficacy, Safety, and Immunogenicity of mRNA-1647 Cytomegalovirus Vaccine in Liver Transplant Candidates and Recipients

Gedaly, R. (PI) & Rockich, A. (CoI)

ModernaTX Incorporated

3/25/24 → 6/25/24

Project: Research project

NRSA Fellowship for Kipp: Bilirubin Catabolism Induces Plasminogen-Activator Inhibitor 1 (PAI-1) Worsening Metabolic Dysfunction

Hinds, T. (PI), Daugherty, A. (CoI) & Starr, M. (CoI)

National Heart Lung and Blood Institute

1/1/24 → 12/31/24

Project: Research project

SBIR: Integration of Compliance Chambers into Diaphragm Displacement Pump to Double the Pumping Flow of Pediatric Paracorporeal Pulsatile Ventricular Assist Device

Wang, D. (PI), Ballard Croft, C. (CoI) & Zwischenberger, J. (CoI)

W-Z Biotech LLC

1/1/24 → 1/31/25

Project: Research project

Start Up Costs Botox: A Phase 2b Double-Blind, Placebo-Controlled, Adaptive, Dose-Escalation Study to Evaluate the Safety and Efficacy of OnabotulinumtoxinA for the Achievement of Primary Fascial Closure Without the Use of Component

Roth, J. (PI) & Rockich, A. (CoI)

AbbVie Incorporated

12/28/23 → 3/27/24

Project: Research project

Startup costs only: CASCADE-LUNG: Cancer Screening Assay Using DELFI; A Clinical Validation Study in Lung

Mullett, T. (PI) & Rockich, A. (CoI)

Delfi Diagnostics Incorporated

11/1/23 → 1/31/24

Project: Research project

PC_ASP_006: PC945 - A Double-Blind, Randomized, Placebo-Controlled Study to Assess the Safety and Efficacy of Nebulized PC945 when added to Systemic Antifungal Therapy for the Treatment of Refractory Invasive Pulmonary Aspergillosis

Nandavaram, S. (PI) & Rockich, A. (CoI)

9/18/23 → 6/30/24

Project: Research project

Low-Dose Short-Term Ketorolac to Reduce Opioid Use and Pain Scores on Orthopaedic Polytrauma Patients

Aneja, A. (PI), Bernard, A. (CoI), Landy, D. (CoI) & Oyler, D. (CoI)

Army Medical Research and Materiel Command

9/1/23 → 11/1/23

Project: Research project

Rebalancing Effector and Regulatory T cell Functions by Tumor Treating Fields (TTF) Therapeutic Potential of Targeting Immune Checkpoints for Cancer Treatment

Marti, F. (PI) & Gedaly, R. (CoI)

Novocure GmbH

8/1/23 → 2/28/25

Project: Research project

A Novel Thoracostomy Tube to Reduce Displacement and Bacterial Introduction

Levy, B. (PI) & Warriner, Z. (CoPI)

Chest Wall Injury Society

7/1/23 → 6/30/24

Project: Research project

Kentucky Lung Cancer Education Awareness Detection Survivorship (LEADS) Prevention and Early Detection and QUILS (Quality Implementation of Lung Cancer Screening)

Knight, J. (PI) & Mullett, T. (CoI)

Anthem Health Plans of Kentucky Inc

6/30/23 → 12/31/24

Project: Research project

Metabolic Profiling of Neuroblastomas

Rellinger, E. (PI)

American Pediatric Surgical Association

6/19/23 → 6/30/24

Project: Research project

Trainee Education - Pacific Northwest Endovascular Conference

Repella, T. (PI)

Medtronics Inc

5/1/23 → 6/30/23

Project: Research project

Development of a Novel Animal Model for Spinal Cord Injury with Sepsis

Patel, S. (PI), Butterfield, T. (CoI), Saito, H. (CoPI) & Stromberg, A. (Former CoI)

National Institute of Neurological Disorders & Stroke

4/15/23 → 3/31/25

Project: Research project

Specialty Tuohy-Borst Side-Arm Introducers (Flexor? Shuttle) Study

Tyagi, S. (PI) & Rockich, A. (CoI)

Cook Research Incorporated

4/4/23 → 12/15/23

Project: Research project

Reducing Lung Cancer Risk among Appalachian Women Using Community-Engaged Intervention Research

Thompson, J. (PI), Hull, P. (CoI), Mullett, T. (CoI), Schoenberg, N. (CoI), Waters, T. (CoI) & Hahn, E. (Former CoI)

National Cancer Institute

2/1/23 → 1/31/24

Project: Research project

Reducing Lung Cancer Risk among Appalachian Women Using Community-Engaged Intervention Research

Thompson, J. (PI), Hull, P. (CoI), Mullett, T. (CoI), Schoenberg, N. (CoI) & Hahn, E. (Former CoI)

National Cancer Institute

2/1/23 → 4/30/24

Project: Research project

Exploring and Planning Dissemination of the Quality Implementation of Lung Cancer Screening (QUILS) # System from the Kentucky LEADS Collaborative

Knight, J. (PI) & Mullett, T. (CoI)

Bristol Myers Squibb Foundation Incorporated

1/1/23 → 11/30/24

Project: Research project

Marines SpeCial Operations PrEparedness (M-SCOPE)

Heebner, N. (PI), Chen, J. (CoI), Conley, C. (CoI), Djafar, T. (CoI), Hoch, M. (CoI), Lephart, S. (CoI), Ross, J. (CoI) & Winters, J. (CoI)

Office of Naval Research

8/1/22 → 1/31/25

Project: Research project

CCSG Pilot: Lung Cancer Prevention Policy: Building Consensus for Radon Control

Stanifer, S. (PI), Hahn, E. (CoI), Mullett, T. (CoI) & Rayens, M. K. (CoI)

National Cancer Institute

7/1/22 → 6/30/23

Project: Research project

Jill Kolesar Scope: State Matching: Kentucky Network for Innovation & Commercialization (#KYNETIC#) Yr 5

Kolesar, J. (PI), Arnold, S. (CoI), Bondada, S. (CoI), Dwoskin, L. (CoI), Gedaly, R. (CoI), Richards, C. (CoI) & Ueland, F. (CoI)

KY Economic Development Cab

7/1/22 → 6/30/24

Project: Research project

Use of Mitlets for Treating Aged Mice with Sepsis

Saito, H. (PI)

Mitrix Bio Incorporated

3/1/22 → 5/31/24

Project: Research project

Scope: Classical and Alternative Renin-Angiotensin System Dysregulation in Sepsis-Associated AKI: A Reverse Translation Approach

Flannery, A. (PI), Neyra Lozano, J. (CoI), Starr, M. (CoI), Waters, C. (CoI) & Morris, P. (Former CoI)

National Institute Diabetes & Digestive & Kidney

1/1/22 → 11/30/22

Project: Research project

SUPPLEMENT: Diversity in Cancer Research Supplement: University of Kentucky

O'Connor, K. (PI), Awuah, S. (CoI), Bocklage, T. (CoI), Cavnar, M. (CoI), Chambers, M. (CoI), Gao, T. (CoI), Gentry, M. (CoI), Goellner, E. (CoI), Kuhs, K. (CoI), Miller, R. (CoI), Wang, X. (CoI) & Williams, L. (CoI)

American Cancer Society

1/1/22 → 12/31/22

Project: Research project

Classical and Alternative Renin-Angiotensin System Dysregulation in Sepsis-Associated AKI: A Reverse Translation Approach

Flannery, A. (PI), Neyra Lozano, J. (CoI), Starr, M. (CoI), Waters, C. (CoI) & Morris, P. (Former CoI)

National Institute Diabetes & Digestive & Kidney

1/1/22 → 8/16/24

Project: Research project

KL2 Scholar Scope: Macrophage Regulation of Peritoneal Carcinomatosis in Gastric Adenocarcinoma

Barry-Hundeyin, M. (PI) & Kelly, T. (CoI)

National Center for Advancing Translational Sciences

1/1/22 → 6/30/24

Project: Research project

MElanoma Research Lymph Node Prediction Implementation National_001 (MERLIN_001)

Burke, E. (PI) & Rockich, A. (CoI)

12/20/21 → 12/20/21

Project: Research project

The DISRUPT Study Direct Lysis of Staph aureus Resistant Pathogen Trial - A Randomized, Double-Blind, Placebo-Controlled Study of the Efficacy and Safety of a Single Dose of Exebacase in Patients Receiving Standard-of-Care Antibiotics for the Treatment of

Bernard, A. (PI) & Rockich, A. (CoI)

ContraFect Corporation

12/15/21 → 7/13/23

Project: Research project

Targeting Glutamine Uptake via ASCT2 Inhibition in MYCN-amplified Neuroblastomas (Project #1)

Rellinger, E. (PI), Moseley, H. (CoI) & Wang, C. (CoI)

National Institute of General Medical Sciences

11/10/21 → 12/31/21

Project: Research project

SBIR Development of a Minimally Invasive Single Cannulation, Compact Single Port Pulsatile Ventricular Assist Device (sppVAD) for Total LV Support

Wang, D. (PI), Ballard Croft, C. (CoI), Sekela, M. (CoI) & Zwischenberger, J. (CoI)

W-Z Biotech LLC

10/1/21 → 6/30/23

Project: Research project

Technology Enabled And Molecular Monitoring of the Allograft and Transplant rEcipient

Shah, M. (PI)

CareDx Incorporated

10/1/21 → 8/7/23

Project: Research project

Study Start-Up: Long-Term Clinical Outcomes Among Renal Transplant Recipients Receiving Tacrolimus: A Multi-Center Retrospective Real-World Database

Gedaly, R. (PI)

Veloxis Pharmaceuticals Incorporated

9/15/21 → 8/19/22

Project: Research project

Surgery

Grants and Contracts

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