Personal profile
Education/Academic qualification
Post Doctoral Fellow, Stanford University
1986
Post Doctoral Fellow, Biozentrum der Universität Basel, Basel, Switzerland
1983
Doctor of Philosophy, University College London, London, England
1979
Bachelor of Science, University College London, London, England
1975
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being -
SDG 14 Life Below Water -
SDG 15 Life on Land
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Collaborations and top research areas from the last five years
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Targeting NNMT to Inhibit Obesity-Associated Breast Cancer Development and Progression
Zhou, B. (PI), Lane, A. (CoI), St Clair, D. (CoI) & Wang, C. (CoI)
9/1/23 → 8/31/26
Project: Research project
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Elucidating Molecular Mechanisms Linking Fructose to Cholesterol Metabolism
Helsley, R. (PI), Graf, G. (CoI), Lane, A. (CoI) & Softic, S. (Former CoI)
National Institute Diabetes & Digestive & Kidney
1/1/22 → 12/31/26
Project: Research project
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Understanding Mechanisms and Consequences of T Cell Co-Receptor Regulated RNA Maturation
Lane, A. (PI), Fan, W.-M. (CoI) & Higashi, R. (CoI)
4/5/21 → 3/31/26
Project: Research project
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Defining the Critical Function and Regulation of NNMT in Breast Cancer Progression and Metastasis
Zhou, B. (PI), Lane, A. (CoI), St Clair, D. (CoI), Wang, C. (CoI) & Zhu, H. (Former CoI)
4/1/21 → 3/31/27
Project: Research project
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Defining Genetic and Metabolic Requirements of Aggressive Breast Cancer (KY SOW)
Lane, A. (PI) & Fan, W.-M. (CoI)
4/1/20 → 3/31/26
Project: Research project
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6-Phosphogluconate dehydrogenase promotes mitochondrial fusion and immune suppression in tumor-associated monocytic suppressor cells
Daneshmandi, S., Yan, Q., Gomez, E. C., Choi, J. E., Katsuta, E., Gharib, E., Singh, P. K., Higashi, R. M., Lane, A. N., Fan, T. W. M., Wang, J., Repasky, E. A., McCarthy, P. L. & Mohammadpour, H., Dec 2026, In: Nature Communications. 17, 1, 229.Research output: Contribution to journal › Article › peer-review
Open Access -
Loss of CD98HC phosphorylation by ATM impairs antiporter trafficking and drives glutamate toxicity in Ataxia telangiectasia
Romero, J. C., Tonapi, S. S., Parihar, M., Loranc, E., Miller, H. E., Lawrence, L. A., Bassani, N., Robledo, D. G., Cao, L., Nie, J., Kanda, K., Stoja, A., Garcia, N., Gorthi, A., Stoveken, B. J., Fan, T. W. M., Cassel, T. A., Zha, S., Lechleiter, J. D. & Musi, N. & 3 others, , Dec 2025, In: Nature Communications. 16, 1, 5109.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
Metabolic Reprogramming in Human Cancer Patients and Patient-Derived Models
Fan, T. W. M., Higashi, R. M. & Lane, A. N., May 2025, In: Cold Spring Harbor perspectives in medicine. 15, 5, a041552.Research output: Contribution to journal › Article › peer-review
6 Scopus citations -
NMR-Based Stable Isotope Tracing of Cancer Metabolism
Lin, P., Lane, A. N. & Fan, T. W. M., 2025, Methods in Molecular Biology. p. 457-504 48 p. (Methods in Molecular Biology; vol. 2855).Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review
3 Scopus citations -
Patient-derived organotypic tissue cultures as a platform to evaluate metabolic reprogramming in breast cancer patients
Fan, T. W. M., Yan, J., Goncalves, C. F. L., Islam, J. M. M., Lin, P., Kaddah, M. M. Y., Higashi, R. M., Lane, A. N., Wang, X. & Zhu, C., May 2025, In: Journal of Biological Chemistry. 301, 5, 108495.Research output: Contribution to journal › Article › peer-review
Open Access