Personal profile
Research Interests
- Enzymes
- Redox catalysis
- Flavin-mediated reactions
- Flavin redox and photochemistry
- Enzyme-functionalized electrodes and membranes
- Spectroscopy
- Mechanistic enzymology
- Enzyme engineering
Education/Academic qualification
Doctor of Philosophy, Yale University
1989
Bachelor of Science, University Of Guelph
1982
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being -
SDG 7 Affordable and Clean Energy
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Collaborations and top research areas from the last five years
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Division of Chemistry: Bifurcation in Context: Essential Ingredients and coupling with partners
Miller, A.-F. (PI)
1/1/26 → 12/31/28
Project: Research project
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Conformational Controls and Consequences of Electron Transfer in Bifurcating Electron Transfer Flavoproteins
Miller, A.-F. (PI)
9/1/20 → 5/31/28
Project: Research project
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Year 3: Scholar Elizabeth Elliott (Mentor Robin Cooper): Beckman Scholars Program: Scholars United by Chemistry: Cultivating Excellence through Science Stewardship (SUCCESS)
Cooper, R. (PI), Risko, C. (CoI), Miller, A.-F. (Former CoI) & Van Eldik, L. (Former CoI)
Arnold and Mabel Beckman Foundation
5/15/24 → 12/31/25
Project: Research project
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Year 3: Scholar Shasanka Lamichhane (Mentor Chad Risko): Beckman Scholars Program: Scholars United by Chemistry: Cultivating Excellence through Science Stewardship (SUCCESS)
Risko, C. (PI), Cooper, R. (Former CoI), Miller, A.-F. (Former CoI) & Van Eldik, L. (Former CoI)
Arnold and Mabel Beckman Foundation
5/15/24 → 8/13/25
Project: Research project
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Year 3: Mentor: Chad Risko (Scholar Shasanka Lamichhane): Beckman Scholars Program: Scholars United by Chemistry: Cultivating Excellence through Science Stewardship (SUCCESS)
Risko, C. (PI), Cooper, R. (Former CoI), Miller, A.-F. (Former CoI) & Van Eldik, L. (Former CoI)
Arnold and Mabel Beckman Foundation
5/15/24 → 8/13/25
Project: Research project
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Cyclometalated Gold(III)-Mediated Cysteine Arylation: A Bioorthogonal Platform for Covalent Targeting of Intrinsically Disordered Proteins
Munugoda, U., Gilpatrick, S. T., Das, D., Parkin, S., Miller, A. F. & Awuah, S. G., Dec 8 2025, In: Angewandte Chemie - International Edition. 64, 50, e202516331.Research output: Contribution to journal › Article › peer-review
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Electrochemical Observation and pH Dependence of All Three Expected Redox Couples in an Extremophilic Bifurcating Electron Transfer Flavoprotein with Fused Subunits
Das, D., El Housseini, W., Brachi, M., Minteer, S. D. & Miller, A. F., Apr 28 2025, In: JACS Au. 5, 4, p. 1689-1706 18 p.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
A single hydrogen bond that tunes flavin redox reactivity and activates it for modification
Das, D. & Miller, A. F., Apr 24 2024, In: Chemical Science. 15, 20, p. 7610-7622 13 p.Research output: Contribution to journal › Article › peer-review
Open Access6 Scopus citations -
Extended conformations of bifurcating electron transfer flavoprotein constitute up to half the population, possibly mediating conformational change
Khan, S. A., Hicks, A., Leite, W. C., Byrnes, J., Gorai, B., Mroginski, M. A., O'Neill, H. & Miller, A. F., Oct 23 2024, In: Chemical Science. 15, 45, p. 18796-18817 22 p.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
Sedimentation of large, soluble proteins up to 140 kDa for 1H-detected MAS NMR and 13C DNP NMR – practical aspects
Bell, D., Lindemann, F., Gerland, L., Aucharova, H., Klein, A., Friedrich, D., Hiller, M., Grohe, K., Meier, T., van Rossum, B., Diehl, A., Hughes, J., Mueller, L. J., Linser, R., Miller, A. F. & Oschkinat, H., Sep 2024, In: Journal of Biomolecular NMR. 78, 3, p. 179-192 14 p.Research output: Contribution to journal › Article › peer-review
Open Access5 Scopus citations
Prizes
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Michael and Kate Barany Award for Young Investigators
Miller, A.-F. (Recipient), 2006
Prize: Honorary award
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College of Arts & Sciences Distinguished Professor
Miller, A.-F. (Recipient), 2022
Prize: Honorary award