Projects and Grants per year
Personal profile
Research Interests
The Schock lab uses Xenopus (frog) and mice to study embryonic development. We are specifically interested in the developing face and the cells that contribute to much of the facial architecture, the neural crest. Research in the lab is centered around two central questions.
1) We are intrested in undestanding how neural crest cells make cell fate decisions, with a current interest in the role of Sox transcription factors in this process.
2) We aim to develop and study disease model for human craniofacial syndromes, with a specific interest in patient-specific variants.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
Developmental Biology, Postdoc, Northwestern University
Aug 2017 → Aug 2024
Doctor of Philosophy, Cincinnati Children's Hospital Medical Center
2017
Master of Science, Wittenberg University
2012
Keywords
- QH301 Biology
- development
- neural crest
- xenopus
- mouse
- QH426 Genetics
- QM Human anatomy
- craniofacial
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Collaborations and top research areas from the last five years
Projects & Grants
- 1 Active
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The Role of SoxE Transcription Factors in Neural Crest Cell Specialization
Schock, B. (PI)
National Institute of Dental and Craniofacial Research
9/16/24 → 8/31/27
Project: Research project
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Shared features of blastula and neural crest stem cells evolved at the base of vertebrates
York, J. R., Rao, A., Huber, P. B., Schock, E. N., Montequin, A., Rigney, S. & LaBonne, C., Sep 2024, In: Nature Ecology and Evolution. 8, 9, p. 1680-1692 13 p.Research output: Contribution to journal › Article › peer-review
Open Access5 Scopus citations -
SoxB1 transcription factors are essential for initiating and maintaining neural plate border gene expression
Schock, E. N., York, J. R., Li, A. P., Tu, A. Y. & LaBonne, C., Jul 2024, In: Development (Cambridge). 151, 14Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
Corrigendum to “A transition from SoxB1 to SoxE transcription factors is essential for progression from pluripotent blastula cells to neural crest cells” [Dev Biol. 2018 Dec 15 444(2):50–61] (Developmental Biology (2018) 444(2) (50–61), (S0012160618302598), (10.1016/j.ydbio.2018.08.008))
Buitrago-Delgado, E., Schock, E. N., Nordin, K. & LaBonne, C., Jan 2023, In: Developmental Biology. 493, p. 12 1 p.Research output: Contribution to journal › Comment/debate
Open Access -
Production and characterization of monoclonal antibodies to Xenopus proteins
Horr, B., Kurtz, R., Pandey, A., Hoffstrom, B. G., Schock, E., LaBonne, C. & Alfandari, D., Feb 2023, In: Development (Cambridge). 150, 4, dev201309.Research output: Contribution to journal › Article › peer-review
Open Access5 Scopus citations -
The developmental and evolutionary origins of cellular pluripotency in the vertebrate neural crest
Schock, E. N., York, J. R. & LaBonne, C., Mar 30 2023, In: Seminars in Cell and Developmental Biology. 138, p. 36-44 9 p.Research output: Contribution to journal › Review article › peer-review
Open Access13 Scopus citations