Projects and Grants per year
Personal profile
Biography
Dr. Brainson joined the faculty of the UK College of Medicine Department of Toxicology and Cancer Biology in 2016. Previously she worked as a post-doctoral fellow at Boston Children's Hospital, where she was part of the Harvard Medical School Department of Genetics, the Boston Children's Hospital Stem Cell Program, and the Harvard Stem Cell Institute. Dr. Brainson completed her Bachelor of Arts at Middlebury College and earned her PhD from Tufts University. Recently, Dr. Brainson was named a Markey Women Strong Distinguished Researcher and grant recipient.
Her research focuses on defining precision medicine opportunities for lung cancer by leveraging ideas and techniques from stem cell biology and epigenetics. Her research is currently funded through the National Cancer Institute, Markey Women Strong, the American Lung Association, the American Institute for Cancer Research, and the American Cancer Society.
Research Interests
Epigenetic control of lung stem cells and lung cancer.
For more information on Dr. Brainson's lab, visit the homepage online.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
Post Doctoral Fellow, Harvard University
2016
Doctor of Philosophy, Tufts University
2009
Bachelor of Arts, Middlebury College
2002
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Collaborations and top research areas from the last five years
Recent external collaboration from the last 5 years on country level. Dive into details by clicking on the dots.
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Investigating the Role of HDL-Associated Serum Amyloid A in Sepsis-induced Acute Lung Injury and Mortality
Shridas, P. (PI), Absher, K. (CoI), Brainson, C. (CoI), Gordon, S. (CoI), Kryscio, R. (CoI), Starr, M. (CoI) & Waters, C. (CoI)
National Heart Lung and Blood Institute
1/1/25 → 11/30/28
Project: Research project
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Targeting Lung Fibrosis Using Epigenetic Therapy
Brainson, C. (PI), Allison, D. (CoI), Beswick, E. (CoI), Liu, J. (CoI), Sturgill, J. (CoI), Weiss, H. (CoI) & Waters, C. (Former CoI)
National Heart Lung and Blood Institute
8/15/24 → 7/31/28
Project: Research project
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Mechanistic and structural insights into a new pro-metastatic collagen glucosyltransferase
Guo, H. (PI), Brainson, C. (CoI) & Chen, L. (CoI)
1/16/24 → 12/31/28
Project: Research project
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Overcoming Therapeutic Resistance in Lung Cancer Using Novel Combination Therapies
Brainson, C. (PI) & Liu, J. (CoI)
Markey Cancer Center Foundation
7/1/23 → 12/31/25
Project: Research project
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Diversity in Cancer Research Supplement: University of Kentucky
O'Connor, K. (PI), Adegboyega, A. (CoI), Awuah, S. (CoI), Blackburn, J. (CoI), Brainson, C. (CoI), Gao, T. (CoI), Hull, P. (CoI), Lee, Y.-S. (CoI), Williams, L. (CoI) & Hahn, E. (Former CoI)
1/1/23 → 12/31/25
Project: Research project
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An Agrin–YAP/TAZ Rigidity Sensing Module Drives EGFR-Addicted Lung Tumorigenesis
Mokhtari, R. B., Sampath, D., Eversole, P., Yu Lin, M. O., Bosykh, D. A., Boopathy, G. T. K., Sivakumar, A., Wang, C. C., Kumar, R., Sheng, J. Y. P., Karasik, E., Foster, B. A., Yu, H., Ling, X., Wu, W., Li, F., Ohler, Z. W., Brainson, C. F., Goodrich, D. W. & Hong, W. & 1 others, , May 29 2025, In: Advanced Science. 12, 20, 2413443.Research output: Contribution to journal › Article › peer-review
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Examining Geographic Disparity: Variation in Cancer Outcomes Within Appalachia
Burus, T., Hull, P. C., Lang Kuhs, K. A., Gao, T., Brainson, C. F. & Evers, B. M., Apr 1 2025, In: Journal of the American College of Surgeons. 240, 4, p. 425-436 12 p.Research output: Contribution to journal › Article › peer-review
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Glycogen drives tumour initiation and progression in lung adenocarcinoma
Clarke, H. A., Hawkinson, T. R., Shedlock, C. J., Medina, T., Ribas, R. A., Wu, L., Liu, Z., Ma, X., Xia, Y., Huang, Y., He, X., Chang, J. E., Young, L. E. A., Juras, J. A., Buoncristiani, M. D., James, A. N., Rushin, A., Merritt, M. E., Mestas, A. & Lamb, J. F. & 11 others, , May 2025, In: Nature Metabolism. 7, 5, p. 952-965 14 p., e44235.Research output: Contribution to journal › Article › peer-review
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L858R/L718Q and L858R/L792H Mutations of EGFR Inducing Resistance Against Osimertinib by Forming Additional Hydrogen Bonds
Imam, I. A., Al Adawi, S., Liu, X., Ellingson, S., Brainson, C. F., Moseley, H. N. B., Zinner, R., Zhang, S. & Shao, Q., Mar 2025, In: Proteins: Structure, Function and Bioinformatics. 93, 3, p. 673-683 11 p.Research output: Contribution to journal › Article › peer-review
1 Scopus citations -
S6K1 is a Targetable Vulnerability in Tumors Exhibiting Plasticity and Therapy Resistance
Ganguly, S., Burikhanov, R., Sviripa, V. M., Ellingson, S., Jiang, J., Gosser, C. M., Orren, D., Goellner, E. M., Shenoy, G. G., Rao, M., D’orazio, J., Brainson, C. F., Zhan, C. G., Spielmann, P. H., Watt, D. S. & Rangnekar, V. M., 2025, In: International Journal of Biological Sciences. 21, 2, p. 454-472 19 p.Research output: Contribution to journal › Article › peer-review
Prizes
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William Rippe Award for Distinguished Research in Lung Cancer
Brainson, C. (Recipient), 2015
Prize: Honorary award
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