Projects and Grants per year
Personal profile
Biography
Dr. Brainson joined the faculty of the UK College of Medicine Department of Toxicology and Cancer Biology in 2016. Previously she worked as a post-doctoral fellow at Boston Children's Hospital, where she was part of the Harvard Medical School Department of Genetics, the Boston Children's Hospital Stem Cell Program, and the Harvard Stem Cell Institute. Dr. Brainson completed her Bachelor of Arts at Middlebury College and earned her PhD from Tufts University. Recently, Dr. Brainson was named a Markey Women Strong Distinguished Researcher and grant recipient.
Her research focuses on defining precision medicine opportunities for lung cancer by leveraging ideas and techniques from stem cell biology and epigenetics. Her research is currently funded through the National Cancer Institute, Markey Women Strong, the American Lung Association, the American Institute for Cancer Research, and the American Cancer Society.
Research Interests
Epigenetic control of lung stem cells and lung cancer.
For more information on Dr. Brainson's lab, visit the homepage online.
Education/Academic qualification
Post Doctoral Fellow, Harvard University
2016
Doctor of Philosophy, Tufts University
2009
Bachelor of Arts, Middlebury College
2002
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being
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Collaborations and top research areas from the last five years
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Enhancing TIL Efficacy in NSCLC through Epigenetic Reprogramming and Computational Modeling
Plaugher, D. (PI), Brainson, C. (CoI), Hao, Z. (CoI), Liu, J. (CoI), Messaoudi Powers, I. (CoI) & Wang, C. (CoI)
7/14/25 → 6/30/27
Project: Research project
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Investigating the Role of HDL-Associated Serum Amyloid A in Sepsis-induced Acute Lung Injury and Mortality
Shridas, P. (PI), Absher, K. (CoI), Brainson, C. (CoI), Gordon, S. (CoI), Kryscio, R. (CoI), Starr, M. (CoI), Sturgill, J. (CoI) & Waters, C. (Former CoI)
National Heart Lung and Blood Institute
1/1/25 → 11/30/28
Project: Research project
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Targeting Lung Fibrosis Using Epigenetic Therapy
Brainson, C. (PI), Allison, D. (CoI), Beswick, E. (CoI), Liu, J. (CoI), Sturgill, J. (CoI), Weiss, H. (CoI) & Waters, C. (Former CoI)
National Heart Lung and Blood Institute
8/15/24 → 7/31/28
Project: Research project
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Mechanistic and structural insights into a new pro-metastatic collagen glucosyltransferase
Guo, H. (PI), Brainson, C. (CoI) & Chen, L. (CoI)
1/16/24 → 12/31/28
Project: Research project
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Aberrant Glycogen in Lung Adenocarcinoma Tumorigenesis
Allison, D. (PI) & Brainson, C. (CoI)
11/1/22 → 6/30/27
Project: Research project
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A Cyclometalated Gold(III) Complex Targets Mitochondrial VDAC1 to Drive Immunometabolic Reprogramming in Cancer
Gilpatrick, S. T., Kim, J. H., Bhogoju, S., Kapur, N., Munugoda, U., Daraezinwa, J., Parkin, S., Barrett, T. A., Brainson, C. F., Plaugher, D. R. & Awuah, S. G., Jun 24 2026, In: Journal of the American Chemical Society. 148, 24, p. 24669-24684 16 p.Research output: Contribution to journal › Article › peer-review
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Mitoception: A Novel Strategy to Alleviate Pulmonary Fibrosis
Bhogoju, S., Patel, P., Kapur, N., Kunjadia, P. D., Aloysius, A., Esoe, D. P., Sturgill, J. L., Brainson, C. F., Chaiswing, L., Sullivan, P. G., Gerber, A. N., Castillo, E., Graham, S. F., Chattopadhyay, I. & Nair, G., Jul 2026, In: Biology. 15, 14, 1112.Research output: Contribution to journal › Article › peer-review
Open Access -
An Agrin–YAP/TAZ Rigidity Sensing Module Drives EGFR-Addicted Lung Tumorigenesis
Mokhtari, R. B., Sampath, D., Eversole, P., Yu Lin, M. O., Bosykh, D. A., Boopathy, G. T. K., Sivakumar, A., Wang, C. C., Kumar, R., Sheng, J. Y. P., Karasik, E., Foster, B. A., Yu, H., Ling, X., Wu, W., Li, F., Ohler, Z. W., Brainson, C. F., Goodrich, D. W. & Hong, W. & 1 others, , May 29 2025, In: Advanced Science. 12, 20, 2413443.Research output: Contribution to journal › Article › peer-review
Open Access6 Scopus citations -
Examining Geographic Disparity: Variation in Cancer Outcomes Within Appalachia
Burus, T., Hull, P. C., Lang Kuhs, K. A., Gao, T., Brainson, C. F. & Evers, B. M., Apr 1 2025, In: Journal of the American College of Surgeons. 240, 4, p. 425-436 12 p.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
Glycogen drives tumour initiation and progression in lung adenocarcinoma
Clarke, H. A., Hawkinson, T. R., Shedlock, C. J., Medina, T., Ribas, R. A., Wu, L., Liu, Z., Ma, X., Xia, Y., Huang, Y., He, X., Chang, J. E., Young, L. E. A., Juras, J. A., Buoncristiani, M. D., James, A. N., Rushin, A., Merritt, M. E., Mestas, A. & Lamb, J. F. & 11 others, , May 2025, In: Nature Metabolism. 7, 5, p. 952-965 14 p., e44235.Research output: Contribution to journal › Article › peer-review
Open Access20 Scopus citations
Prizes
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William Rippe Award for Distinguished Research in Lung Cancer
Brainson, C. (Recipient), 2015
Prize: Honorary award