Projects and Grants per year
Personal profile
Research Interests
Research Programs:
- Genomic Instability, Epigenetics and Metabolism
Research Focus:
- Oxidative stress, redox proteomics, chemotherapy-induced cognitive impairment (chemobrain), Alzheimer's disease.
Our laboratory studies these and other aspects of oxidative stress in brain membranes using a variety of techniques, including immunochemical, metabolomic, and proteomics methods.
Area of Study: Free radical chemistry/Alzheimer's disease
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
Doctor of Philosophy, Duke University
1974
Bachelor of Arts, University of Maine
1968
Keywords
- QH426 Genetics
- QD Chemistry
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Collaborations and top research areas from the last five years
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University of Kentucky Markey Cancer Center - Cancer Center Support Grant (Plan to Enhance Diversity (PED))
Evers, B. M., Adams, V., Allison, D., Anthony, L., Arnold, S., Bocklage, T., Burris, J., Butterfield, D. A., Chen, L., COHEN, D., Durbin, E. B., Ellingson, S., Gao, T., Hands, I., Higashi, R., Huang, B., Hull, P., Jeong, J. C., Kavuluru, R., Kuhs, K., Kunos, C., Lee, E., Liu, J., McGarry, R., Moseley, H., Mullett, T., O'Connor, K., Patel, R., Plattner, R., Rogers, J., Shelton, B., St Clair, D., Stanley, S., Stapleton, J., Sturgill, J., Vanderford, N., Villano, PhD, J., Wang, C., Wei, S., Weiss, H., Williams, L., Woodward, J., Yan, D., Zhang, S., Zhou, B. & Kolesar, J.
7/8/13 → 6/30/28
Project: Research project
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University of Kentucky Markey Cancer Center - Cancer Center Support Grant (Prime)
Evers, B. M., Adams, V., Allison, D., Anthony, L., Arnold, S., Bocklage, T., Burris, J., Butterfield, D. A., Chen, L., Durbin, E. B., Ellingson, S., Gao, T., Hands, I., Higashi, R., Huang, B., Hull, P., Jeong, J. C., Kavuluru, R., Kuhs, K., Lee, E., Liu, J., McGarry, R., Moseley, H., Mullett, T., O'Connor, K., Patel, R., Plattner, R., Rogers, J., Shelton, B., St Clair, D., Stapleton, J., Sturgill, J., Vanderford, N., Villano, PhD, J., Wang, C., Wei, S., Weiss, H., Williams, L., Yan, D., Zhang, S., Zhou, B., COHEN, D., Kolesar, J., Kunos, C., Stanley, S. & Woodward, J.
7/8/13 → 6/30/28
Project: Research project
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University of Kentucky Markey Cancer Center - Cancer Center Support Grant (Clinical Protocol and Data Management (CPMD))
Evers, B. M., Adams, V., Allison, D., Anthony, L., Arnold, S., Bocklage, T., Burris, J., Butterfield, D. A., Chen, L., COHEN, D., Durbin, E. B., Ellingson, S., Gao, T., Hands, I., Higashi, R., Huang, B., Hull, P., Jeong, J. C., Kavuluru, R., Kuhs, K., Kunos, C., Lee, E., Liu, J., McGarry, R., Moseley, H., Mullett, T., O'Connor, K., Patel, R., Plattner, R., Rogers, J., Shelton, B., St Clair, D., Stanley, S., Stapleton, J., Sturgill, J., Vanderford, N., Villano, PhD, J., Wang, C., Wei, S., Weiss, H., Williams, L., Woodward, J., Yan, D., Zhang, S., Zhou, B. & Kolesar, J.
7/8/13 → 6/30/28
Project: Research project
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University of Kentucky Markey Cancer Center - Cancer Center Support Grant (Community Outreach and Engagement (COE))
Evers, B. M., Adams, V., Allison, D., Anthony, L., Arnold, S., Bocklage, T., Burris, J., Butterfield, D. A., Chen, L., COHEN, D., Durbin, E. B., Ellingson, S., Gao, T., Hands, I., Higashi, R., Huang, B., Hull, P., Jeong, J. C., Kavuluru, R., Kuhs, K., Kunos, C., Lee, E., Liu, J., McGarry, R., Moseley, H., Mullett, T., O'Connor, K., Patel, R., Plattner, R., Rogers, J., Shelton, B., St Clair, D., Stanley, S., Stapleton, J., Sturgill, J., Vanderford, N., Villano, PhD, J., Wang, C., Wei, S., Weiss, H., Williams, L., Woodward, J., Yan, D., Zhang, S., Zhou, B. & Kolesar, J.
7/8/13 → 6/30/28
Project: Research project
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Chemo Induced Cognition Impairment C2419
St Clair, D., Butterfield, D. A., D'Orazio, J., Sorge, C., Weiss, H. & Bondada, S.
KY Cabinet for Health and Family Services
7/1/20 → 6/30/21
Project: Research project
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Biliverdin Reductase-A integrates insulin signaling with mitochondrial metabolism through phosphorylation of GSK3β
Lanzillotta, C., Tramutola, A., Lanzillotta, S., Greco, V., Pagnotta, S., Sanchini, C., Di Angelantonio, S., Forte, E., Rinaldo, S., Paone, A., Cutruzzolà, F., Cimini, F. A., Barchetta, I., Cavallo, M. G., Urbani, A., Butterfield, D. A., Di Domenico, F., Paul, B. D., Perluigi, M., Duarte, J. M. N., & 1 others , Jul 2024, In: Redox Biology. 73, 103221.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
OXIDATIVE DAMAGE IN NEURODEGENERATION: ROLES IN THE PATHOGENESIS AND PROGRESSION OF ALZHEIMER DISEASE
Perluigi, M., Di Domenico, F. & Butterfield, D. A., Jan 2024, In: Physiological Reviews. 104, 1, p. 103-197 95 p.Research output: Contribution to journal › Review article › peer-review
23 Scopus citations -
Protein Oxidation in Aging and Alzheimer’s Disease Brain
Sultana, R. & Butterfield, D. A., May 2024, In: Antioxidants. 13, 5, 574.Research output: Contribution to journal › Review article › peer-review
Open Access3 Scopus citations -
Cellular Stress Response (Hormesis) in Response to Bioactive Nutraceuticals with Relevance to Alzheimer Disease
Butterfield, D. A., Boyd-Kimball, D. & Reed, T. T., Mar 1 2023, In: Antioxidants and Redox Signaling. 38, 7-9, p. 643-669 27 p.Research output: Contribution to journal › Review article › peer-review
Open Access6 Scopus citations -
Oxidative Stress in Brain in Amnestic Mild Cognitive Impairment
Butterfield, D. A., Feb 2023, In: Antioxidants. 12, 2, 462.Research output: Contribution to journal › Review article › peer-review
Open Access12 Scopus citations
Prizes
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Research Foundation Faculty Research Award, University of Kentucky
Butterfield, D. Allan (Recipient), 1979
Prize: Honorary award
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William B. Sturgill Award for Graduate Education
Butterfield, D. Allan (Recipient), 1997
Prize: Honorary award
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Fellow, Society for Redox Biology and Medicine
Butterfield, D. Allan (Recipient), 2012
Prize: Honorary award
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Biomedical Science Research Award, National Institutes of Health (NIH)
Butterfield, D. Allan (Recipient), 1972
Prize: Honorary award