Grants and Contracts per year
Personal profile
Research Interests
Research Programs:
- Genomic Instability, Epigenetics and Metabolism
Research Focus:
- Oxidative stress, redox proteomics, chemotherapy-induced cognitive impairment (chemobrain), Alzheimer's disease.
Our laboratory studies these and other aspects of oxidative stress in brain membranes using a variety of techniques, including immunochemical, metabolomic, and proteomics methods.
Area of Study: Free radical chemistry/Alzheimer's disease
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
Doctor of Philosophy, Duke University
1974
Bachelor of Arts, Univ Of Maine - Orono
1968
Keywords
- QH426 Genetics
- QD Chemistry
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- 1 Similar Profiles
Network
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(PQ9) A Redox-Mediated Mechanism of Chemotherapy-Induced Cognitive Impairment
St Clair, D., Barron, S., Weiss, H., Bondada, S. & Butterfield, D. A.
9/15/17 → 7/31/23
Project: Research project
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(PQ9) A Redox-Mediated Mechanism of Chemotherapy-Induced Cognitive Impairment
Bondada, S., Barron, S., Butterfield, D. A., St Clair, D. & Weiss, H.
9/15/17 → 7/31/23
Project: Research project
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(PQ9) A Redox-Mediated Mechanism of Chemotherapy-Induced Cognitive Impairment
Butterfield, D. A., Barron, S., Bondada, S., St Clair, D. & Weiss, H.
9/15/17 → 7/31/23
Project: Research project
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University of Kentucky Markey Cancer Center - Cancer Center Support Grant
Evers, B. M., Adams, V., Allison, D., Anthony, L., Arnold, S., Bocklage, T., Burris, J., Butterfield, D. A., Chen, L., Dignan, M., Durbin, E., Ellingson, S., Gandhapudi, S., Gao, T., Higashi, R., Huang, B., Hull, P., Jeong, J. C., Kavuluru, R., Kolesar, J., Kuhs, K., Kunos, C., Lee, E., Liu, J., McGarry, R., Moseley, H., O'Connor, K., Patel, R., Plattner, R., Rangnekar, V., Rogers, J., Shelton, B., St Clair, D., Stanley, S., Stapleton, J., Sturgill, J., Vanderford, N., Wang, C., Wei, S., Weiss, H., Williams, L., Yan, D., Zhang, S., Zhou, B., COHEN, D., D'Orazio, J., Feddock, J., Gosky, D., Hao, Z., He, C., Hodges, K., Jennings, C., Liu, J., Purdom, M., Saeed, H., Shi, Q., Stewart, R., Studts, J., Thorson, J., Tucker, T., Vanderpool, R., Woodward, J., Wu, J. & Zhu, H.
7/8/13 → 6/30/23
Project: Research project
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Chemo Induced Cognition Impairment C2419
St Clair, D., Butterfield, D. A., D'Orazio, J., Sorge, C., Weiss, H. & Bondada, S.
KY Cabinet for Health and Family Services
7/1/20 → 6/30/21
Project: Research project
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Cellular Stress Response (Hormesis) in Response to Bioactive Nutraceuticals with Relevance to Alzheimer Disease
Butterfield, D. A., Boyd-Kimball, D. & Reed, T. T., Mar 1 2023, In: Antioxidants and Redox Signaling. 38, 7-9, p. 643-669 27 p.Research output: Contribution to journal › Review article › peer-review
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Oxidative Stress in Brain in Amnestic Mild Cognitive Impairment
Butterfield, D. A., Feb 2023, In: Antioxidants. 12, 2, 462.Research output: Contribution to journal › Review article › peer-review
Open Access -
Aberrant crosstalk between insulin signaling and mTOR in young Down syndrome individuals revealed by neuronal-derived extracellular vesicles
Perluigi, M., Picca, A., Montanari, E., Calvani, R., Marini, F., Matassa, R., Tramutola, A., Villani, A., Familiari, G., Domenico, F. D., Butterfield, D. A., Oh, K. J., Marzetti, E., Valentini, D. & Barone, E., Aug 2022, In: Alzheimer's and Dementia. 18, 8, p. 1498-1510 13 p.Research output: Contribution to journal › Article › peer-review
Open Access5 Scopus citations -
Altered Metabolism in Alzheimer Disease Brain: Role of Oxidative Stress
Rummel, N. G. & Butterfield, D. A., Jun 1 2022, In: Antioxidants and Redox Signaling. 36, 16-18, p. 1289-1305 17 p.Research output: Contribution to journal › Review article › peer-review
17 Scopus citations -
CAPE and its synthetic derivative VP961 restore BACH1/NRF2 axis in Down Syndrome
Pagnotta, S., Tramutola, A., Barone, E., Di Domenico, F., Pittalà, V., Salerno, L., Folgiero, V., Caforio, M., Locatelli, F., Petrini, S., Butterfield, D. A. & Perluigi, M., Apr 2022, In: Free Radical Biology and Medicine. 183, p. 1-13 13 p.Research output: Contribution to journal › Review article › peer-review
5 Scopus citations
Prizes
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Presidential Awards for Excellence in Science, Mathematics, and Engineering Mentoring (PAESMEM)
Butterfield, D. Allan (Recipient), 1998
Prize: Honorary award
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Research Foundation Faculty Research Award, University of Kentucky
Butterfield, D. Allan (Recipient), 1979
Prize: Honorary award
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Honorary Doctor of Science Degree - Commencement, University of Maine, 2002
Butterfield, D. Allan (Recipient), 2002
Prize: Honorary award
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The Honorable Order of Kentucky Colonels
Butterfield, D. Allan (Recipient), 1995
Prize: Honorary award
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Fellow, Society for Redox Biology and Medicine
Butterfield, D. Allan (Recipient), 2012
Prize: Honorary award