Projects and Grants per year
Personal profile
Research Interests
Research Programs:
- Genomic Instability, Epigenetics and Metabolism
Research Focus:
- Oxidative stress, redox proteomics, chemotherapy-induced cognitive impairment (chemobrain), Alzheimer's disease.
Our laboratory studies these and other aspects of oxidative stress in brain membranes using a variety of techniques, including immunochemical, metabolomic, and proteomics methods.
Area of Study: Free radical chemistry/Alzheimer's disease
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
Doctor of Philosophy, Duke University
1974
Bachelor of Arts, University of Maine
1968
Keywords
- QH426 Genetics
- QD Chemistry
Fingerprint
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Collaborations and top research areas from the last five years
Recent external collaboration from the last 5 years on country level. Dive into details by clicking on the dots.
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University of Kentucky Markey Cancer Center - Cancer Center Support Grant (Clinical Protocol and Data Management (CPMD))
Evers, B. M. (PI), Adams, V. (CoI), Allison, D. (CoI), Anthony, L. (CoI), Arnold, S. (CoI), Bocklage, T. (CoI), Burris, J. (CoI), Butterfield, D. A. (CoI), Chen, L. (CoI), COHEN, D. (CoI), Durbin, E. B. (CoI), Ellingson, S. (CoI), Gao, T. (CoI), Hands, I. (CoI), Higashi, R. (CoI), Huang, B. (CoI), Hull, P. (CoI), Jeong, J. C. (CoI), Kavuluru, R. (CoI), Kuhs, K. (CoI), Kunos, C. (CoI), Lee, E. (CoI), Liu, J. (CoI), McGarry, R. (CoI), Moseley, H. (CoI), Mullett, T. (CoI), O'Connor, K. (CoI), Patel, R. (CoI), Plattner, R. (CoI), Rogers, J. (CoI), Shelton, B. (CoI), St Clair, D. (CoI), Stanley, S. (CoI), Stapleton, J. (CoI), Sturgill, J. (CoI), Vanderford, N. (CoI), Villano, PhD, J. (CoI), Wang, C. (CoI), Wei, S. (CoI), Weiss, H. (CoI), Williams, L. (CoI), Woodward, J. (CoI), Yan, D. (CoI), Zhang, S. (CoI), Zhou, B. (CoI) & Kolesar, J. (Former CoI)
7/8/13 → 6/30/28
Project: Research project
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University of Kentucky Markey Cancer Center - Cancer Center Support Grant (Community Outreach and Engagement (COE))
Evers, B. M. (PI), Adams, V. (CoI), Allison, D. (CoI), Anthony, L. (CoI), Arnold, S. (CoI), Bocklage, T. (CoI), Burris, J. (CoI), Butterfield, D. A. (CoI), Chen, L. (CoI), COHEN, D. (CoI), Durbin, E. B. (CoI), Ellingson, S. (CoI), Gao, T. (CoI), Hands, I. (CoI), Higashi, R. (CoI), Huang, B. (CoI), Hull, P. (CoI), Jeong, J. C. (CoI), Kavuluru, R. (CoI), Kuhs, K. (CoI), Kunos, C. (CoI), Lee, E. (CoI), Liu, J. (CoI), McGarry, R. (CoI), Moseley, H. (CoI), Mullett, T. (CoI), O'Connor, K. (CoI), Patel, R. (CoI), Plattner, R. (CoI), Rogers, J. (CoI), Shelton, B. (CoI), St Clair, D. (CoI), Stanley, S. (CoI), Stapleton, J. (CoI), Sturgill, J. (CoI), Vanderford, N. (CoI), Villano, PhD, J. (CoI), Wang, C. (CoI), Wei, S. (CoI), Weiss, H. (CoI), Williams, L. (CoI), Woodward, J. (CoI), Yan, D. (CoI), Zhang, S. (CoI), Zhou, B. (CoI) & Kolesar, J. (Former CoI)
7/8/13 → 6/30/28
Project: Research project
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University of Kentucky Markey Cancer Center - Cancer Center Support Grant (Prime)
Evers, B. M. (PI), Adams, V. (CoI), Allison, D. (CoI), Anthony, L. (CoI), Arnold, S. (CoI), Bocklage, T. (CoI), Brainson, C. (CoI), Burris, J. (CoI), Burrows Franco, A. (CoI), Butterfield, D. A. (CoI), Chen, L. (CoI), Durbin, E. B. (CoI), Ellingson, S. (CoI), Gandhapudi, S. (CoI), Gao, T. (CoI), Hands, I. (CoI), Hao, Z. (CoI), Higashi, R. (CoI), Huang, B. (CoI), Hull, P. (CoI), Jeong, J. C. (CoI), Kavuluru, R. (CoI), Kuhs, K. (CoI), Lee, E. (CoI), Liu, J. (CoI), McGarry, R. (CoI), McLouth, L. (CoI), Moseley, H. (CoI), Mullett, T. (CoI), O'Connor, K. (CoI), Patel, R. (CoI), Plattner, R. (CoI), Rogers, J. (CoI), Shelton, B. (CoI), St Clair, D. (CoI), Sturgill, J. (CoI), Vanderford, N. (CoI), Villano, PhD, J. (CoI), Wang, C. (CoI), Wei, S. (CoI), Weiss, H. (CoI), Williams, L. (CoI), Yan, D. (CoI), Zhang, S. (CoI), Zhou, B. (CoI), COHEN, D. (Former CoI), Kolesar, J. (Former CoI), Kunos, C. (Former CoI), Stanley, S. (Former CoI), Stapleton, J. (Former CoI) & Woodward, J. (Former CoI)
7/8/13 → 6/30/28
Project: Research project
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University of Kentucky Markey Cancer Center - Cancer Center Support Grant (Plan to Enhance Diversity (PED))
Evers, B. M. (PI), Adams, V. (CoI), Allison, D. (CoI), Anthony, L. (CoI), Arnold, S. (CoI), Bocklage, T. (CoI), Burris, J. (CoI), Butterfield, D. A. (CoI), Chen, L. (CoI), COHEN, D. (CoI), Durbin, E. B. (CoI), Ellingson, S. (CoI), Gao, T. (CoI), Hands, I. (CoI), Higashi, R. (CoI), Huang, B. (CoI), Hull, P. (CoI), Jeong, J. C. (CoI), Kavuluru, R. (CoI), Kuhs, K. (CoI), Kunos, C. (CoI), Lee, E. (CoI), Liu, J. (CoI), McGarry, R. (CoI), Moseley, H. (CoI), Mullett, T. (CoI), O'Connor, K. (CoI), Patel, R. (CoI), Plattner, R. (CoI), Rogers, J. (CoI), Shelton, B. (CoI), St Clair, D. (CoI), Stanley, S. (CoI), Stapleton, J. (CoI), Sturgill, J. (CoI), Vanderford, N. (CoI), Villano, PhD, J. (CoI), Wang, C. (CoI), Wei, S. (CoI), Weiss, H. (CoI), Williams, L. (CoI), Woodward, J. (CoI), Yan, D. (CoI), Zhang, S. (CoI), Zhou, B. (CoI) & Kolesar, J. (Former CoI)
7/8/13 → 6/30/28
Project: Research project
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Chemo Induced Cognition Impairment C2419
St Clair, D. (PI), Butterfield, D. A. (CoI), D'Orazio, J. (CoI), Sorge, C. (CoI), Weiss, H. (CoI) & Bondada, S. (CoPI)
KY Cabinet for Health and Family Services
7/1/20 → 6/30/21
Project: Research project
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Extracellular vesicles released by ALL patients contain HNE-adducted proteins: Implications of collateral damage
Ho, J., Sukati, S., Taylor, T., Carter, S., Fuller, B., Marmo, A., Sorge, C., D'Orazio, J., Butterfield, D. A., Bondada, S., Weiss, H., St Clair, D. K. & Chaiswing, L., Feb 1 2025, In: Free Radical Biology and Medicine. 227, p. 312-321 10 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Activation of the Neuronal Cell Cycle in Brains in Amnestic Mild Cognitive Impairment: Early Involvement in the Progression of Alzheimer's Disease
Butterfield, D. A., Aug 20 2024, In: Journal of Alzheimer's Disease. 100, s1, p. S277-S281Research output: Contribution to journal › Review article › peer-review
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Biliverdin Reductase-A integrates insulin signaling with mitochondrial metabolism through phosphorylation of GSK3β
Lanzillotta, C., Tramutola, A., Lanzillotta, S., Greco, V., Pagnotta, S., Sanchini, C., Di Angelantonio, S., Forte, E., Rinaldo, S., Paone, A., Cutruzzolà, F., Cimini, F. A., Barchetta, I., Cavallo, M. G., Urbani, A., Butterfield, D. A., Di Domenico, F., Paul, B. D., Perluigi, M. & Duarte, J. M. N. & 1 others, , Jul 2024, In: Redox Biology. 73, 103221.Research output: Contribution to journal › Article › peer-review
Open Access7 Scopus citations -
Correction to: Extraction of redox extracellular vesicles using exclusion-based sample preparation (Analytical and Bioanalytical Chemistry, (2024), 416, 28, (6317-6331), 10.1007/s00216-024-05518-z)
Banadaki, M. D., Rummel, N. G., Backus, S., Butterfield, D. A., St. Clair, D. K., Campbell, J. M., Zhong, W., Mayer, K., Berry, S. M. & Chaiswing, L., Dec 2024, In: Analytical and Bioanalytical Chemistry. 416, 29, p. 7187-7188 2 p.Research output: Contribution to journal › Comment/debate
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Extraction of redox extracellular vesicles using exclusion-based sample preparation
Banadaki, M. D., Rummel, N. G., Backus, S., Butterfield, D. A., St. Clair, D. K., Campbell, J. M., Zhong, W., Mayer, K., Berry, S. M. & Chaiswing, L., Nov 2024, In: Analytical and Bioanalytical Chemistry. 416, 28, p. 6317-6331 15 p.Research output: Contribution to journal › Article › peer-review
Prizes
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The Alumni Professor of Chemistry, University of Kentucky, 2002
Butterfield, D. A. (Recipient), 2002
Prize: Honorary award
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Biomedical Science Research Award, National Institutes of Health (NIH)
Butterfield, D. A. (Recipient), 1972
Prize: Honorary award
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Honorary Doctor of Science Degree - Commencement, University of Maine, 2002
Butterfield, D. A. (Recipient), 2002
Prize: Honorary award
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William B. Sturgill Award for Graduate Education
Butterfield, D. A. (Recipient), 1997
Prize: Honorary award