Calculated based on number of publications stored in Pure and citations from Scopus
1990 …2022

Research activity per year

If you made any changes in Pure these will be visible here soon.

Personal profile

Research Interests

The broad goal of our research is to delineate the molecular basis of human disease to identify novel treatment approaches.

One major focus of our studies is the characterization of the RIT1 oncoprotein, which is a key regulator of signal transduction pathways that control normal cell growth and differentiation. Using whole-exome sequence analysis on a subgroup of 'oncogene-negative' tumors allowed our recent identification of somatic RIT1 mutations in ~2.5% of lung adenocarcinoma cases. Importantly, RIT1 mutations were found to be mutually exclusive with all previously known driver mutations, and expression of mutant RIT1 induces cellular transformation. We are interested in further investigating the functional role of RIT1 in lung adenocarcinoma with the long-term goal of creating novel avenues for therapeutic intervention. 

Expertise related to UN Sustainable Development Goals

In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):

  • SDG 3 - Good Health and Well-being

Education/Academic qualification

Doctor of Philosophy, Purdue University

1990

Bachelor of Science, Univ Of Wisconsin-Madison

1985

Fingerprint

Dive into the research topics where Douglas Andres is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
  • 1 Similar Profiles

Network

Recent external collaboration from the last 5 years on country level. Dive into details by clicking on the dots.