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Gregory Jicha, MD

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1985 …2023

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  • 2018

    Electrophysiological repetition effects in persons with mild cognitive impairment depend upon working memory demand

    Broster, L. S., Jenkins, S. L., Holmes, S. D., Edwards, M. G., Jicha, G. A. & Jiang, Y., Aug 2018, In: Neuropsychologia. 117, p. 13-25 13 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    2 Scopus citations
  • Global Cerebral Atrophy Detected by Routine Imaging: Relationship with Age, Hippocampal Atrophy, and White Matter Hyperintensities

    Al-Janabi, O. M., Panuganti, P., Abner, E. L., Bahrani, A. A., Murphy, R., Bardach, S. H., Caban-Holt, A., Nelson, P. T., Gold, B. T., Smith, C. D., Wilcock, D. M. & Jicha, G. A., May 1 2018, In: Journal of Neuroimaging. 28, 3, p. 301-306 6 p.

    Research output: Contribution to journalArticlepeer-review

    7 Scopus citations
  • High complement levels in astrocyte-derived exosomes of Alzheimer disease

    Goetzl, E. J., Schwartz, J. B., Abner, E. L., Jicha, G. A. & Kapogiannis, D., Mar 2018, In: Annals of Neurology. 83, 3, p. 544-552 9 p.

    Research output: Contribution to journalArticlepeer-review

    178 Scopus citations
  • Motivators for Alzheimer’s disease clinical trial participation

    Bardach, S. H., Holmes, S. D. & Jicha, G. A., Feb 1 2018, In: Aging clinical and experimental research. 30, 2, p. 209-212 4 p.

    Research output: Contribution to journalArticlepeer-review

    6 Scopus citations
  • Multimodal and Multiscale Deep Neural Networks for the Early Diagnosis of Alzheimer’s Disease using structural MR and FDG-PET images

    Department of Genetics University of North Carolina, Dec 1 2018, In: Scientific Reports. 8, 1, 5697.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    182 Scopus citations
  • Spared behavioral repetition effects in Alzheimer’s disease linked to an altered neural mechanism at posterior cortex

    Broster, L. S., Li, J., Wagner, B., Smith, C. D., Jicha, G. A., Schmitt, F. A., Munro, N., Haney, R. H. & Jiang, Y., Sep 14 2018, In: Journal of Clinical and Experimental Neuropsychology. 40, 8, p. 761-776 16 p.

    Research output: Contribution to journalArticlepeer-review

    3 Scopus citations
  • Uncovering the heterogeneity and temporal complexity of neurodegenerative diseases with Subtype and Stage Inference

    Dec 1 2018, In: Nature Communications. 9, 1, 4273.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    136 Scopus citations
  • 2017

    A cognitive electrophysiological signature differentiates amnestic mild cognitive impairment from normal aging

    Li, J., Broster, L. S., Jicha, G. A., Munro, N. B., Schmitt, F. A., Abner, E., Kryscio, R., Smith, C. D. & Jiang, Y., Jan 19 2017, In: Alzheimer's Research and Therapy. 9, 1, 3.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    19 Scopus citations
  • A Comparison of Sex Differences in Psychotropic Medication Use in Older People with Alzheimer’s Disease in the US and Finland

    Moga, D. C., Taipale, H., Tolppanen, A. M., Tanskanen, A., Tiihonen, J., Hartikainen, S., Wu, Q., Jicha, G. A. & Gnjidic, D., Jan 1 2017, In: Drugs and Aging. 34, 1, p. 55-65 11 p.

    Research output: Contribution to journalArticlepeer-review

    13 Scopus citations
  • 15 Scopus citations
  • Altered cargo proteins of human plasma endothelial cell–derived exosomes in atherosclerotic cerebrovascular disease

    Goetzl, E. J., Schwartz, J. B., Mustapic, M., Lobach, I. V., Daneman, R., Abner, E. L. & Jicha, G. A., Aug 2017, In: FASEB Journal. 31, 8, p. 3689-3694 6 p.

    Research output: Contribution to journalArticlepeer-review

    60 Scopus citations
  • Association of plasma neurofilament light with neurodegeneration in patients with Alzheimer disease

    Department of Genetics University of North Carolina, May 2017, In: JAMA Neurology. 74, 5, p. 557-566 10 p.

    Research output: Contribution to journalArticlepeer-review

    475 Scopus citations
  • Bladder antimuscarinics and cognitive decline in elderly patients

    Moga, D. C., Abner, E. L., Wu, Q. & Jicha, G. A., Jan 1 2017, In: Alzheimer's and Dementia: Translational Research and Clinical Interventions. 3, 1, p. 139-148 10 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    25 Scopus citations
  • Cascaded Multi-view Canonical Correlation (CaMCCo) for Early Diagnosis of Alzheimer's Disease via Fusion of Clinical, Imaging and Omic Features

    Singanamalli, A., Wang, H., Madabhushi, A., Weiner, M., Aisen, P., Petersen, R., Jack, C., Jagust, W., Trojanowki, J., Toga, A., Beckett, L., Green, R., Saykin, A., Morris, J., Shaw, L., Kaye, J., Quinn, J., Silbert, L., Lind, B., Carter, R., & 221 othersDolen, S., Schneider, L., Pawluczyk, S., Beccera, M., Teodoro, L., Spann, B., Brewer, J., Vanderswag, H., Fleisher, A., Heidebrink, J., Lord, J., Mason, S., Albers, C., Knopman, D., Johnson, K., Doody, R., Villanueva-Meyer, J., Chowdhury, M., Rountree, S., Dang, M., Stern, Y., Honig, L., Bell, K., Ances, B., Carroll, M., Creech, M., Franklin, E., Mintun, M., Schneider, S., Oliver, A., Marson, D., Griffith, R., Clark, D., Geldmacher, D., Brockington, J., Roberson, E., Natelson Love, M., Grossman, H., Mitsis, E., Shah, R., Detoledo-Morrell, L., Duara, R., Varon, D., Greig, M., Roberts, P., Albert, M., Onyike, C., D'Agostino, D., Kielb, S., Galvin, J., Cerbone, B., Michel, C., Pogorelec, D., Rusinek, H., De Leon, M., Glodzik, L., De Santi, S., Doraiswamy, P., Petrella, J., Borges-Neto, S., Wong, T., Coleman, E., Smith, C., Jicha, G., Hardy, P., Sinha, P., Oates, E., Conrad, G., Porsteinsson, A., Goldstein, B., Martin, K., Makino, K., Ismail, M., Brand, C., Mulnard, R., Thai, G., Mc-Adams-Ortiz, C., Womack, K., Mathews, D., Quiceno, M., Levey, A., Lah, J., Cellar, J., Burns, J., Swerdlow, R., Brooks, W., Apostolova, L., Tingus, K., Woo, E., Silverman, D., Lu, P., Bartzokis, G., Graff-Radford, N., Parfitt, F., Kendall, T., Johnson, H., Farlow, M., Marie Hake, A., Matthews, B., Brosch, J., Herring, S., Hunt, C., Dyck, C., Carson, R., MacAvoy, M., Varma, P., Chertkow, H., Bergman, H., Hosein, C., Black, S., Stefanovic, B., Caldwell, C., Robin Hsiung, G. Y., Feldman, H., Mudge, B., Assaly, M., Finger, E., Pasternack, S., Rachisky, I., Trost, D., Kertesz, A., Bernick, C., Munic, D., Mesulam, M. M., Lipowski, K., Weintraub, S., Bonakdarpour, B., Kerwin, D., Wu, C. K., Johnson, N., Sadowsky, C., Villena, T., Scott Turner, R., Johnson, K., Reynolds, B., Sperling, R., Johnson, K., Marshall, G., Yesavage, J., Taylor, J., Lane, B., Rosen, A., Tinklenberg, J., Sabbagh, M., Belden, C., Jacobson, S., Sirrel, S., Kowall, N., Killiany, R., Budson, A., Norbash, A., Lynn Johnson, P., Obisesan, T., Wolday, S., Allard, J., Lerner, A., Ogrocki, P., Tatsuoka, C., Fatica, P., Fletcher, E., Maillard, P., Olichney, J., Decarli, C., Carmichael, O., Kittur, S., Borrie, M., Lee, T. Y., Robbartha, Johnson, S., Asthana, S., Carlsson, C., Potkin, S., Preda, A., Nguyen, D., Tariot, P., Burke, A., Trncic, N., Reeder, S., Bates, V., Capote, H., Rainka, M., Scharre, D., Kataki, M., Adeli, A., Zimmerman, E., Celmins, D., Brown, A., Pearlson, G., Blank, K., Anderson, K., Flashman, L., Seltzer, M., Hynes, M., Santulli, R., Sink, K., Gordineer, L., Williamson, J., Garg, P., Watkins, F., Ott, B., Querfurth, H., Tremont, G., Salloway, S., Malloy, P., Correia, S., Rosen, H., Miller, B., Perry, D., Mintzer, J., Spicer, K., Bachman, D., Pomara, N., Hernando, R., Sarrael, A., Relkin, N., Chaing, G., Lin, M., Ravdin, L., Smith, A., Ashok Raj, B. & Fargher, K., Dec 1 2017, In: Scientific Reports. 7, 1, 8137.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    7 Scopus citations
  • Development, validation and application of a new fornix template for studies of aging and preclinical Alzheimer's disease

    Brown, C. A., Johnson, N. F., Anderson-Mooney, A. J., Jicha, G. A., Shaw, L. M., Trojanowski, J. Q., Van Eldik, L. J., Schmitt, F. A., Smith, C. D. & Gold, B. T., 2017, In: NeuroImage: Clinical. 13, p. 106-115 10 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    34 Scopus citations
  • Functional human GRIN2B promoter polymorphism and variation of mental processing speed in older adults

    Jiang, Y., Lin, M. K., Jicha, G. A., Ding, X., McIlwrath, S. L., Fardo, D. W., Broster, L. S., Schmitt, F. A., Kryscio, R. & Lipsky, R. H., 2017, In: Aging. 9, 4, p. 1293-1306 14 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    4 Scopus citations
  • Hippocampal sclerosis in older patients practical examples and guidance with a focus on cerebral age-related TDP-43 with sclerosis

    Cykowski, M. D., Powell, S. Z., Schulz, P. E., Takei, H., Rivera, A. L., Jackson, R. E., Roman, G., Jicha, G. A. & Nelson, P. T., Aug 2017, In: Archives of Pathology and Laboratory Medicine. 141, 8, p. 1113-1126 14 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    20 Scopus citations
  • Longitudinal measurement and hierarchical classification framework for the prediction of Alzheimer's disease

    Huang, M., Yang, W., Feng, Q., Chen, W., Weiner, M. W., Aisen, P., Petersen, R., Jack, C. R., Jagust, W., Trojanowki, J. Q., Toga, A. W., Beckett, L., Green, R. C., Saykin, A. J., Morris, J. C., Shaw, L. M., Kaye, J., Quinn, J., Silbert, L., Lind, B., & 219 othersCarter, R., Dolen, S., Schneider, L. S., Pawluczyk, S., Beccera, M., Teodoro, L., Spann, B. M., Brewer, J., Vanderswag, H., Fleisher, A., Heidebrink, J. L., Lord, J. L., Mason, S. S., Albers, C. S., Knopman, D., Johnson, K., Doody, R. S., Villanueva-Meyer, J., Chowdhury, M., Rountree, S., Dang, M., Stern, Y., Honig, L. S., Bell, K. L., Ances, B., Carroll, M., Creech, M. L., Franklin, E., Mintun, M. A., Schneider, S., Oliver, A., Marson, D., Griffith, R., Clark, D., Geldmacher, D., Brockington, J., Roberson, E., Love, M. N., Grossman, H., Mitsis, E., Shah, R. C., DeToledo-Morrell, L., Duara, R., Varon, D., Greig, M. T., Roberts, P., Albert, M., Onyike, C., D'Agostino, D., Kielb, S., Galvin, J. E., Cerbone, B., Michel, C. A., Pogorelec, D. M., Rusinek, H., De Leon, M. J., Glodzik, L., De Santi, S., Murali Doraiswamy, P., Petrella, J. R., Borges-Neto, S., Wong, T. Z., Coleman, E., Smith, C. D., Jicha, G., Hardy, P., Sinha, P., Oates, E., Conrad, G., Porsteinsson, A. P., Goldstein, B. S., Martin, K., Makino, K. M., Saleem Ismail, M., Brand, C., Mulnard, R. A., Thai, G., Mc-Adams-Ortiz, C., Womack, K., Mathews, D., Quiceno, M., Levey, A. I., Lah, J. J., Cellar, J. S., Burns, J. M., Swerdlow, R. H., Brooks, W. M., Apostolova, L., Tingus, K., Woo, E., Silverman, D. H. S., Lu, P. H., Bartzokis, G., Graff-Radford, N. R., Parfitt, F., Kendall, T., Johnson, H., Farlow, M. R., Hake, A. M., Brosch, J. R., Herring, S., Hunt, C., Van Dyck, C. H., Carson, R. E., MacAvoy, M. G., Varma, P., Chertkow, H., Bergman, H., Hosein, C., Black, S., Stefanovic, B., Caldwell, C., Hsiung, G. Y. R., Feldman, H., Mudge, B., Assaly, M., Finger, E., Pasternack, S., Rachisky, I., Trost, D., Kertesz, A., Bernick, C., Munic, D., Mesulam, M. M., Lipowski, K., Weintraub, S., Bonakdarpour, B., Kerwin, D., Wu, C. K., Johnson, N., Sadowsky, C., Villena, T., Turner, R. S., Reynolds, B., Sperling, R. A., Johnson, K. A., Marshall, G., Yesavage, J., Taylor, J. L., Lane, B., Rosen, A., Tinklenberg, J., Sabbagh, M. N., Belden, C. M., Jacobson, S. A., Sirrel, S. A., Kowall, N., Killiany, R., Budson, A. E., Norbash, A., Lynn Johnson, P., Obisesan, T. O., Wolday, S., Allard, J., Lerner, A., Ogrocki, P., Tatsuoka, C., Fatica, P., Maillard, P., Olichney, J., DeCarli, C., Carmichael, O., Kittur, S., Borrie, M., Lee, T. Y., Bartha, R., Johnson, S., Asthana, S., Carlsson, C. M., Potkin, S. G., Preda, A., Nguyen, D., Tariot, P., Burke, A., Trncic, N., Reeder, S., Bates, V., Capote, H., Rainka, M., Scharre, D. W., Kataki, M., Adeli, A., Zimmerman, E. A., Celmins, D., Brown, A. D., Pearlson, G. D., Blank, K., Anderson, K., Flashman, L. A., Seltzer, M., Hynes, M. L., Santulli, R. B., Sink, K. M., Gordineer, L., Williamson, J. D., Garg, P., Watkins, F., Ott, B. R., Querfurth, H., Tremont, G., Salloway, S., Malloy, P., Correia, S., Rosen, H. J., Miller, B. L., Perry, D., Mintzer, J., Spicer, K., Bachman, D., Pomara, N., Hernando, R., Sarrael, A., Relkin, N., Chaing, G., Lin, M., Ravdin, L., Smith, A., Raj, B. A. & Fargher, K., Jan 12 2017, In: Scientific Reports. 7, 39880.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    39 Scopus citations
  • Low Arousal Positive Emotional Stimuli Attenuate Aberrant Working Memory Processing in Persons with Mild Cognitive Impairment

    Broster, L. S., Jenkins, S. L., Holmes, S. D., Jicha, G. A. & Jiang, Y., 2017, In: Journal of Alzheimer's Disease. 60, 4, p. 1333-1349 17 p.

    Research output: Contribution to journalArticlepeer-review

    1 Scopus citations
  • Neuropathological and genetic correlates of survival and dementia onset in synucleinopathies: a retrospective analysis

    Irwin, D. J., Grossman, M., Weintraub, D., Hurtig, H. I., Duda, J. E., Xie, S. X., Lee, E. B., Van Deerlin, V. M., Lopez, O. L., Kofler, J. K., Nelson, P. T., Jicha, G. A., Woltjer, R., Quinn, J. F., Kaye, J., Leverenz, J. B., Tsuang, D., Longfellow, K., Yearout, D., Kukull, W., & 4 othersKeene, C. D., Montine, T. J., Zabetian, C. P. & Trojanowski, J. Q., Jan 1 2017, In: The Lancet Neurology. 16, 1, p. 55 1 p.

    Research output: Contribution to journalArticlepeer-review

    267 Scopus citations
  • Optimizing medication appropriateness in older adults: a randomized clinical interventional trial to decrease anticholinergic burden

    Moga, D. C., Abner, E. L., Rigsby, D. N., Eckmann, L., Huffmyer, M., Murphy, R. R., Coy, B. B. & Jicha, G. A., May 23 2017, In: Alzheimer's Research and Therapy. 9, 1, 36.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    26 Scopus citations
  • Outcomes after diagnosis of mild cognitive impairment in a large autopsy series

    Abner, E. L., Kryscio, R. J., Schmitt, F. A., Fardo, D. W., Moga, D. C., Ighodaro, E. T., Jicha, G. A., Yu, L., Dodge, H. H., Xiong, C., Woltjer, R. L., Schneider, J. A., Cairns, N. J., Bennett, D. A. & Nelson, P. T., Apr 2017, In: Annals of Neurology. 81, 4, p. 549-559 11 p.

    Research output: Contribution to journalArticlepeer-review

    72 Scopus citations
  • Pattern Discovery in Brain Imaging Genetics via SCCA Modeling with a Generic Non-convex Penalty

    Du, L., Liu, K., Yao, X., Yan, J., Risacher, S. L., Han, J., Guo, L., Saykin, A. J., Shen, L., Weiner, M. W., Aisen, P., Petersen, R., Jack, C. R., Jagust, W., Trojanowki, J. Q., Toga, A. W., Beckett, L., Green, R. C., Morris, J., Shaw, L. M., & 293 othersKhachaturian, Z., Sorensen, G., Carrillo, M., Kuller, L., Raichle, M., Paul, S., Davies, P., Fillit, H., Hefti, F., Holtzman, D., Mesulam, M. M., Potter, W., Snyder, P., Schwartz, A., Montine, T., Thomas, R. G., Donohue, M., Walter, S., Gessert, D., Sather, T., Jiminez, G., Balasubramanian, A. B., Mason, J., Sim, I., Harvey, D., Bernstein, M., Fox, N., Thompson, P., Schuff, N., Decarli, C., Borowski, B., Gunter, J., Senjem, M., Vemuri, P., Jones, D., Kantarci, K., Ward, C., Koeppe, R. A., Foster, N., Reiman, E. M., Chen, K., Mathis, C., Landau, S., Cairns, N. J., Franklin, E., Taylor-Reinwald, L., Lee, V., Korecka, M., Figurski, M., Crawford, K., Neu, S., Foroud, T. M., Potkin, S., Faber, K., Kim, S., Nho, K., Thal, L., Buckholtz, N., Albert, M., Frank, R., Hsiao, J., Kaye, J., Quinn, J., Silbert, L., Lind, B., Carter, R., Dolen, S., Schneider, L. S., Pawluczyk, S., Beccera, M., Teodoro, L., Spann, B. M., Brewer, J., Vanderswag, H., Fleisher, A., Heidebrink, J. L., Lord, J. L., Mason, S. S., Albers, C. S., Knopman, D., Johnson, K., Doody, R. S., Villanueva-Meyer, J., Pavlik, V., Shibley, V., Chowdhury, M., Rountree, S., Dang, M., Stern, Y., Honig, L. S., Bell, K. L., Ances, B., Carroll, M., Creech, M. L., Franklin, E., Mintun, M. A., Schneider, S., Oliver, A., Marson, D., Geldmacher, D., Love, M. N., Griffith, R., Clark, D., Brockington, J., Roberson, E., Grossman, H., Mitsis, E., Shah, R. C., Detoledo-Morrell, L., Duara, R., Greig-Custo, M. T., Barker, W., Onyike, C., D'Agostino, D., Kielb, S., Sadowski, M., Sheikh, M. O., Ulysse, A., Gaikwad, M., Murali Doraiswamy, P., Petrella, J. R., Borges-Neto, S., Wong, T. Z., Coleman, E., Arnold, S. E., Karlawish, J. H., Wolk, D. A., Clark, C. M., Smith, C. D., Jicha, G., Hardy, P., Sinha, P., Oates, E., Conrad, G., Lopez, O. L., Oakley, M. A., Simpson, D. M., Porsteinsson, A. P., Goldstein, B. S., Martin, K., Makino, K. M., Ismail, M. S., Brand, C., Preda, A., Nguyen, D., Womack, K., Mathews, D., Quiceno, M., Levey, A. I., Lah, J. J., Cellar, J. S., Burns, J. M., Swerdlow, R. H., Brooks, W. M., Apostolova, L., Tingus, K., Woo, E., Silverman, D. H. S., Lu, P. H., Bartzokis, G., Graff-Radford, N. R., Parfitt, F., Poki-Walker, K., Farlow, M. R., Marie Hake, A., Matthews, B. R., Brosch, J. R., Herring, S., Van Dyck, C. H., Carson, R. E., MacAvoy, M. G., Varma, P., Chertkow, H., Bergman, H., Hosein, C., Black, S., Stefanovic, B., Caldwell, C., Robin Hsiung, G. Y., Mudge, B., Sossi, V., Feldman, H., Assaly, M., Finger, E., Pasternack, S., Rachisky, I., Rogers, J., Trost, D., Kertesz, A., Bernick, C., Munic, D., Rogalski, E., Lipowski, K., Weintraub, S., Bonakdarpour, B., Kerwin, D., Wu, C. K., Johnson, N., Sadowsky, C., Villena, T., Scott Turner, R., Johnson, K., Reynolds, B., Sperling, R. A., Johnson, K. A., Marshall, G., Yesavage, J., Taylor, J. L., Lane, B., Rosen, A., Tinklenberg, J., Sabbagh, M. N., Belden, C. M., Jacobson, S. A., Sirrel, S. A., Kowall, N., Killiany, R., Budson, A. E., Norbash, A., Lynn Johnson, P., Obisesan, T. O., Wolday, S., Allard, J., Lerner, A., Ogrocki, P., Tatsuoka, C., Fatica, P., Fletcher, E., Maillard, P., Olichney, J., Decarli, C., Carmichael, O., Kittur, S., Borrie, M., Lee, T. Y., Bartha, R., Johnson, S., Asthana, S., Carlsson, C. M., Tariot, P., Burke, A., Milliken, A. M., Trncic, N., Fleisher, A., Reeder, S., Bates, V., Capote, H., Rainka, M., Scharre, D. W., Kataki, M., Kelly, B., Zimmerman, E. A., Celmins, D., Brown, A. D., Pearlson, G. D., Blank, K., Anderson, K., Flashman, L. A., Seltzer, M., Hynes, M. L., Santulli, R. B., Sink, K. M., Gordineer, L., Williamson, J. D., Garg, P., Watkins, F., Ott, B. R., Tremont, G., Daiello, L. A., Salloway, S., Malloy, P., Correia, S., Rosen, H. J., Miller, B. L., Perry, D., Mintzer, J., Spicer, K., Bachman, D., Pomara, N., Hernando, R., Sarrael, A., Schultz, S. K., Ekstam Smith, K., Koleva, H., Nam, K. W., Shim, H., Relkin, N., Chaing, G., Lin, M., Ravdin, L., Smith, A., Ashok Raj, B. & Fargher, K., Dec 1 2017, In: Scientific Reports. 7, 1, 14052.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    7 Scopus citations
  • Risk factors and global cognitive status related to brain arteriolosclerosis in elderly individuals

    Ighodaro, E. T., Abner, E. L., Fardo, D. W., Lin, A. L., Katsumata, Y., Schmitt, F. A., Kryscio, R. J., Jicha, G. A., Neltner, J. H., Monsell, S. E., Kukull, W. A., Moser, D. K., Appiah, F., Bachstetter, A. D., Van Eldik, L. J. & Nelson, P. T., Jan 1 2017, In: Journal of Cerebral Blood Flow and Metabolism. 37, 1, p. 201-216 16 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    52 Scopus citations
  • The Effectiveness of Small-group Community-based Information Sessions on Clinical Trial Recruitment for Secondary Prevention of Alzheimer's Disease

    Tarrant, S. D., Bardach, S. H., Bates, K., Nichols, H., Towner, J., Tamatha, C., Caban-Holt, A., Van-Eldik, L. J., Murphy, R. R., Sperling, R. & Jicha, G. A., May 1 2017, In: Alzheimer Disease and Associated Disorders. 31, 2, p. 141-145 5 p.

    Research output: Contribution to journalArticlepeer-review

    8 Scopus citations
  • Transethnic genome-wide scan identifies novel Alzheimer's disease loci

    Jul 2017, In: Alzheimer's and Dementia. 13, 7, p. 727-738 12 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    95 Scopus citations
  • White Matter Hyperintensity Associations with Cerebral Blood Flow in Elderly Subjects Stratified by Cerebrovascular Risk

    Bahrani, A. A., Powell, D. K., Yu, G., Johnson, E. S., Jicha, G. A. & Smith, C. D., Apr 1 2017, In: Journal of Stroke and Cerebrovascular Diseases. 26, 4, p. 779-786 8 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    36 Scopus citations
  • 2016

    1H-MRS metabolites in adults with Down syndrome: Effects of dementia

    Lin, A. L., Powell, D., Caban-Holt, A., Jicha, G., Robertson, W., Gold, B. T., Davis, R., Abner, E., Wilcock, D. M., Schmitt, F. A. & Head, E., 2016, In: NeuroImage: Clinical. 11, p. 728-735 8 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    27 Scopus citations
  • Aging-related tau astrogliopathy (ARTAG): harmonized evaluation strategy

    Kovacs, G. G., Ferrer, I., Grinberg, L. T., Alafuzoff, I., Attems, J., Budka, H., Cairns, N. J., Crary, J. F., Duyckaerts, C., Ghetti, B., Halliday, G. M., Ironside, J. W., Love, S., Mackenzie, I. R., Munoz, D. G., Murray, M. E., Nelson, P. T., Takahashi, H., Trojanowski, J. Q., Ansorge, O., & 52 othersArzberger, T., Baborie, A., Beach, T. G., Bieniek, K. F., Bigio, E. H., Bodi, I., Dugger, B. N., Feany, M., Gelpi, E., Gentleman, S. M., Giaccone, G., Hatanpaa, K. J., Heale, R., Hof, P. R., Hofer, M., Hortobágyi, T., Jellinger, K., Jicha, G. A., Ince, P., Kofler, J., Kövari, E., Kril, J. J., Mann, D. M., Matej, R., McKee, A. C., McLean, C., Milenkovic, I., Montine, T. J., Murayama, S., Lee, E. B., Rahimi, J., Rodriguez, R. D., Rozemüller, A., Schneider, J. A., Schultz, C., Seeley, W., Seilhean, D., Smith, C., Tagliavini, F., Takao, M., Thal, D. R., Toledo, J. B., Tolnay, M., Troncoso, J. C., Vinters, H. V., Weis, S., Wharton, S. B., White, C. L., Wisniewski, T., Woulfe, J. M., Yamada, M. & Dickson, D. W., Jan 1 2016, In: Acta Neuropathologica. 131, 1, p. 87-102 16 p.

    Research output: Contribution to journalArticlepeer-review

    293 Scopus citations
  • Alzheimer's biomarkers are correlated with brain connectivity in older adults differentially during resting and task states

    Jiang, Y., Huang, H., Abner, E., Broster, L. S., Jicha, G. A., Schmitt, F. A., Kryscio, R., Andersen, A., Powell, D., Van Eldik, L., Gold, B. T., Nelson, P. T., Smith, C. & Ding, M., 2016, In: Frontiers in Aging Neuroscience. 8, FEB, 15.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    21 Scopus citations
  • Alzheimer's disease risk polymorphisms regulate gene expression in the ZCWPW1 and the CELF1 loci

    Feb 2016, In: PLoS ONE. 11, 2, e0148717.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    65 Scopus citations
  • A novel Alzheimer disease locus located near the gene encoding tau protein

    Jun, G., Ibrahim-Verbaas, C. A., Vronskaya, M., Lambert, J. C., Chung, J., Naj, A. C., Kunkle, B. W., Wang, L. S., Bis, J. C., Bellenguez, C., Harold, D., Lunetta, K. L., Destefano, A. L., Grenier-Boley, B., Sims, R., Beecham, G. W., Smith, A. V., Chouraki, V., Hamilton-Nelson, K. L., Ikram, M. A., & 332 othersFievet, N., Denning, N., Martin, E. R., Schmidt, H., Kamatani, Y., Dunstan, M. L., Valladares, O., Laza, A. R., Zelenika, D., Ramirez, A., Foroud, T. M., Choi, S. H., Boland, A., Becker, T., Kukull, W. A., Van Der Lee, S. J., Pasquier, F., Cruchaga, C., Beekly, D., Fitzpatrick, A. L., Hanon, O., Gill, M., Barber, R., Gudnason, V., Campion, D., Love, S., Bennett, D. A., Amin, N., Berr, C., Tsolaki, M., Buxbaum, J. D., Lopez, O. L., Deramecourt, V., Fox, N. C., Cantwell, L. B., Tárraga, L., Dufouil, C., Hardy, J., Crane, P. K., Eiriksdottir, G., Hannequin, D., Clarke, R., Evans, D., Mosley, T. H., Letenneur, L., Brayne, C., Maier, W., De Jager, P., Emilsson, V., Dartigues, J. F., Hampel, H., Kamboh, M. I., De Bruijn, R. F. A. G., Tzourio, C., Pastor, P., Larson, E. B., Rotter, J. I., O'Donovan, M. C., Montine, T. J., Nalls, M. A., Mead, S., Reiman, E. M., Jonsson, P. V., Holmes, C., St George-Hyslop, P. H., Boada, M., Passmore, P., Wendland, J. R., Schmidt, R., Morgan, K., Winslow, A. R., Powell, J. F., Carasquillo, M., Younkin, S. G., Jakobsdóttir, J., Kauwe, J. S. K., Wilhelmsen, K. C., Rujescu, D., Nöthen, M. M., Hofman, A., Jones, L., Haines, J. L., Psaty, B. M., Van Broeckhoven, C., Holmans, P., Launer, L. J., Mayeux, R., Lathrop, M., Goate, A. M., Escott-Price, V., Seshadri, S., Pericak-Vance, M. A., Amouyel, P., Williams, J., Van Duijn, C. M., Schellenberg, G. D., Farrer, L. A., Adams, P. M., Albert, M. S., Albin, R. L., Apostolova, L. G., Arnold, S. E., Asthana, S., Atwood, C. S., Baldwin, C. T., Barmada, M. M., Barnes, L. L., Beach, T. G., Bigio, E. H., Bird, T. D., Blacker, D., Boeve, B. F., Bowen, J. D., Boxer, A., Burke, J. R., Cairns, N. J., Cao, C., Carlson, C. S., Carlsson, C. M., Carney, R. M., Carrasquillo, M. M., Carroll, S. L., Chui, H. C., Clark, D. G., Corneveaux, J., Cribbs, D. H., Crocco, E. A., DeCarli, C., DeKosky, S. T., Yesim Demirci, F., Dick, M., Dickson, D. W., Doody, R. S., Duara, R., Ertekin-Taner, N., Faber, K. M., Fairchild, T. J., Fallon, K. B., Farlow, M. R., Ferris, S., Frosch, M. P., Galasko, D. R., Gearing, M., Geschwind, D. H., Ghetti, B., Gilbert, J. R., Glass, J. D., Graff-Radford, N. R., Green, R. C., Growdon, J. H., Hakonarson, H., Hamilton, R. L., Harrell, L. E., Head, E., Honig, L. S., Huebinger, R. M., Huentelman, M. J., Hulette, C. M., Hyman, B. T., Jarvik, G. P., Jicha, G. A., Jin, L. W., Karydas, A., Kaye, J. A., Kim, R., Koo, E. H., Kowall, N. W., Kramer, J. H., LaFerla, F. M., Lah, J. J., Leverenz, J. B., Levey, A. I., Li, G., Lieberman, A. P., Lin, C. F., Lyketsos, C. G., Mack, W. J., Marson, D. C., Martiniuk, F., Mash, D. C., Masliah, E., McCormick, W. C., McCurry, S. M., McDavid, A. N., McKee, A. C., Mesulam, M., Miller, B. L., Miller, C. A., Miller, J. W., Morris, J. C., Mukherjee, S., Murrell, J. R., Myers, A. J., O'Bryant, S., Olichney, J. M., Pankratz, V. S., Parisi, J. E., Partch, A., Paulson, H. L., Perry, W., Peskind, E., Petersen, R. C., Pierce, A., Poon, W. W., Potter, H., Quinn, J. F., Raj, A., Raskind, M., Reisberg, B., Reisch, J. S., Reitz, C., Ringman, J. M., Roberson, E. D., Rogaeva, E., Rosen, H. J., Rosenberg, R. N., Royall, D. R., Sager, M. A., Sano, M., Saykin, A. J., Schneider, J. A., Schneider, L. S., Seeley, W. W., Smith, A. G., Sonnen, J. A., Spina, S., Stern, R. A., Tanzi, R. E., Thornton-Wells, T. A., Trojanowski, J. Q., Troncoso, J. C., Tsuang, D. W., Van Deerlin, V. M., Van Eldik, L. J., Vardarajan, B. N., Vinters, H. V., Vonsattel, J. P., Weintraub, S., Welsh-Bohmer, K. A., Williamson, J., Wishnek, S., Woltjer, R. L., Wright, C. B., Wu, C. K., Yu, C. E., Yu, L., Thomas, C., Gerrish, A., Chapman, J., Stretton, A., Morgan, A., Oldham, H., Owen, M. J., Kehoe, P. G., Medway, C., Brown, K., Lord, J., Turton, J., Hooper, N. M., Vardy, E., Warren, J. D., Schott, J. M., Uphill, J., Hollingworth, P., Ryan, N., Rossor, M., Collinge, J., Ben-Shlomo, Y., Makrina, D., Gkatzima, O., Lupton, M., Koutroumani, M., Avramidou, D., Germanou, A., Jessen, F., Riedel-Heller, S., Dichgans, M., Heun, R., Kölsch, H., Schürmann, B., Herold, C., Lacour, A., Drichel, D., Hoffmann, P., Kornhuber, J., Gu, W., Feulner, T., Mayhaus, M., Pichler, S., Riemenschneider, M., van den Bussche, H., Lawlor, B., Lynch, A., Mann, D., Smith, A. D., Warden, D., Wilcock, G., Heuser, I., Wiltfang, J., Frölich, L., Hüll, M., Mayo, K., Livingston, G., Bass, N. J., Gurling, H., McQuillin, A., Gwilliam, R., Deloukas, P., Al-Chalabi, A., Shaw, C. E., Singleton, A. B., Guerreiro, R., Russo, G., Jöckel, K. H., Moebus, S., Klopp, N., Wichmann, H. E., Ma, L., Bisceglio, G., Fisher, E., Warner, N., Pickering-Brown, S., Craig, D., Johnston, J. A., McGuinness, B., Todd, S., Rubinsztein, D. C., Lovestone, S., Bayer, A., Gallacher, J., Proitsi, P. & Ortega-Cubero, S., Jan 1 2016, In: Molecular Psychiatry. 21, 1, p. 108-117 10 p.

    Research output: Contribution to journalArticlepeer-review

    160 Scopus citations
  • Assessment of the genetic variance of late-onset Alzheimer's disease

    May 1 2016, In: Neurobiology of Aging. 41, p. 200.e13-200.e20

    Research output: Contribution to journalArticlepeer-review

    Open Access
    46 Scopus citations
  • Association between anticholinergic medication use and cognition, brain metabolism, and brain atrophy in cognitively normal older adults

    Jun 2016, In: JAMA Neurology. 73, 6, p. 721-732 12 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    186 Scopus citations
  • Brain pathologies in extreme old age

    Neltner, J. H., Abner, E. L., Jicha, G. A., Schmitt, F. A., Patel, E., Poon, L. W., Marla, G., Green, R. C., Davey, A., Johnson, M. A., Jazwinski, S. M., Kim, S., Davis, D., Woodard, J. L., Kryscio, R. J., Van Eldik, L. J. & Nelson, P. T., Jan 1 2016, In: Neurobiology of Aging. 37, p. 1-11 11 p.

    Research output: Contribution to journalArticlepeer-review

    63 Scopus citations
  • Decreased synaptic proteins in neuronal exosomes of frontotemporal dementia and Alzheimer's disease

    Goetzl, E. J., Kapogiannis, D., Schwartz, J. B., Lobach, I. V., Goetzl, L., Abner, E. L., Jicha, G. A., Karydas, A. M., Boxer, A. & Miller, B. L., Dec 2016, In: FASEB Journal. 30, 12, p. 4141-4148 8 p.

    Research output: Contribution to journalArticlepeer-review

    218 Scopus citations
  • Early role of vascular dysregulation on late-onset Alzheimer's disease based on multifactorial data-driven analysis

    Jun 21 2016, In: Nature Communications. 7, 11934.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    595 Scopus citations
  • Extracellular vesicle-associated aβ mediates trans-neuronal bioenergetic and ca2+-handling deficits in alzheimer’s disease models

    Eitan, E., Hutchison, E. R., Marosi, K., Comotto, J., Mustapic, M., Nigam, S. M., Suire, C., Maharana, C., Jicha, G. A., Liu, D., Machairaki, V., Witwer, K. W., Kapogiannis, D. & Mattson, M. P., 2016, In: npj Aging and Mechanisms of Disease. 2, 1, 16019.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    77 Scopus citations
  • Genomics and CSF analyses implicate thyroid hormone in hippocampal sclerosis of aging

    Nelson, P. T., Katsumata, Y., Nho, K., Artiushin, S. C., Jicha, G. A., Wang, W. X., Abner, E. L., Saykin, A. J., Kukull, W. A., Alzheimer’s Disease Neuroimaging Initiative (ADNI), D. N. I. & Fardo, D. W., Dec 1 2016, In: Acta Neuropathologica. 132, 6, p. 841-858 18 p.

    Research output: Contribution to journalArticlepeer-review

    24 Scopus citations
  • Hippocampal sclerosis but not normal aging or Alzheimer disease is associated with TDP-43 pathology in the basal forebrain of aged persons

    Cykowski, M. D., Takei, H., Van Eldik, L. J., Schmitt, F. A., Jicha, G. A., Powell, S. Z. & Nelson, P. T., May 1 2016, In: Journal of Neuropathology and Experimental Neurology. 75, 5, p. 397-407 11 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    32 Scopus citations
  • Peripheral (deep) but not periventricular MRI white matter hyperintensities are increased in clinical vascular dementia compared to Alzheimer's disease

    Smith, C. D., Johnson, E. S., Van Eldik, L. J., Jicha, G. A., Schmitt, F. A., Nelson, P. T., Kryscio, R. J., Murphy, R. R. & Wellnitz, C. V., Mar 1 2016, In: Brain and Behavior. 6, 3, p. 1-11 11 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    31 Scopus citations
  • Plasma neuronal exosomal levels of Alzheimer's disease biomarkers in normal aging

    Abner, E. L., Jicha, G. A., Shaw, L. M., Trojanowski, J. Q. & Goetzl, E. J., May 1 2016, In: Annals of Clinical and Translational Neurology. 3, 5, p. 399-403 5 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    39 Scopus citations
  • Rural-Urban Differences in Alzheimer's Disease and Related Disorders Diagnostic Prevalence in Kentucky and West Virginia

    Abner, E. L., Jicha, G. A., Christian, W. J. & Schreurs, B. G., Jun 1 2016, In: Journal of Rural Health. 32, 3, p. 314-320 7 p.

    Research output: Contribution to journalArticlepeer-review

    31 Scopus citations
  • Self-Reported Sleep Apnea and Dementia Risk: Findings from the Prevention of Alzheimer's Disease with Vitamin E and Selenium Trial

    Ding, X., Kryscio, R. J., Turner, J., Jicha, G. A., Cooper, G., Caban-Holt, A., Schmitt, F. A. & Abner, E. L., Dec 1 2016, In: Journal of the American Geriatrics Society. 64, 12, p. 2472-2478 7 p.

    Research output: Contribution to journalArticlepeer-review

    21 Scopus citations
  • 2015

    A clinical trial to validate event-related potential markers of Alzheimer's disease in outpatient settings

    Cecchi, M., Moore, D. K., Sadowsky, C. H., Solomon, P. R., Doraiswamy, P. M., Smith, C. D., Jicha, G. A., Budson, A. E., Arnold, S. E. & Fadem, K. C., Dec 1 2015, In: Alzheimer's and Dementia: Diagnosis, Assessment and Disease Monitoring. 1, 4, p. 387-394 8 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    42 Scopus citations
  • Assessing the discriminant ability, reliability, and comparability of multiple short forms of the boston naming test in an Alzheimer's disease center cohort

    Katsumata, Y., Mathews, M., Abner, E. L., Jicha, G. A., Caban-Holt, A., Smith, C. D., Nelson, P. T., Kryscio, R. J., Schmitt, F. A. & Fardo, D. W., Apr 18 2015, In: Dementia and Geriatric Cognitive Disorders. 39, 3-4, p. 215-227 13 p.

    Research output: Contribution to journalArticlepeer-review

    20 Scopus citations
  • Association of long runs of homozygosity with Alzheimer disease among African American individuals

    Ghani, M., Reitz, C., Cheng, R., Vardarajan, B. N., Jun, G., Sato, C., Naj, A., Rajbhandary, R., Wang, L. S., Valladares, O., Lin, C. F., Larson, E. B., Graff-Radford, N. R., Evans, D., De Jager, P. L., Crane, P. K., Buxbaum, J. D., Murrell, J. R., Raj, T., Ertekin-Taner, N., & 153 othersLogue, M., Baldwin, C. T., Green, R. C., Barnes, L. L., Cantwell, L. B., Fallin, M. D., Go, R. C. P., Griffith, P. A., Obisesan, T. O., Manly, J. J., Lunetta, K. L., Kamboh, M. I., Lopez, O. L., Bennett, D. A., Hendrie, H., Hall, K. S., Goate, A. M., Byrd, G. S., Kukull, W. A., Foroud, T. M., Haines, J. L., Farrer, L. A., Pericak-Vance, M. A., Lee, J. H., Schellenberg, G. D., St. George-Hyslop, P., Mayeux, R., Rogaeva, E., Albert, M. S., Albin, R. L., Apostolova, L. G., Arnold, S. E., Barber, R., Barmada, M. M., Beach, T. G., Beecham, G. W., Beekly, D., Bigio, E. H., Bird, T. D., Blacker, D., Boeve, B. F., Bowen, J. D., Boxer, A., Burke, J. R., Cai, G., Cairns, N. J., Cao, C., Carlson, C. S., Carney, R. M., Carroll, S. L., Chui, H. C., Clark, D. G., Cribbs, D. H., Crocco, E. A., Cruchaga, C., DeCarli, C., DeKosky, S. T., Demirci, F. Y., Dick, M., Faber, K. M., Fallon, K. B., Ferris, S., Frosch, M. P., Galasko, D. R., Ganguli, M., Gearing, M., Geschwind, D. H., Ghetti, B., Gilbert, J. R., Gilman, S., Glass, J. D., Growdon, J. H., Hakonarson, H., Hamilton, R. L., Hamilton-Nelson, K. L., Haroutunian, V., Harrell, L. E., Honig, L. S., Hulette, C. M., Hyman, B. T., Jarvik, G. P., Jicha, G. A., Jin, L. W., Karydas, A., Kauwe, J. S. K., Kaye, J. A., Kim, R., Koo, E. H., Kowall, N. W., Kramer, J. H., Kramer, P., LaFerla, F. M., Lah, J. J., Lang-Walker, R., Leverenz, J. B., Levey, A. I., Li, G., Lieberman, A. P., Lyketsos, C. G., Mack, W. J., Marson, D. C., Martiniuk, F., Mash, D. C., Masliah, E., McCormick, W. C., McCurry, S. M., McDavid, A. N., McKee, A. C., Mesulam, M., Miller, B. L., Miller, C. A., Miller, J. W., Montine, T. J., Morris, J. C., Olichney, J. M., Parisi, J. E., Peskind, E., Petersen, R. C., Pierce, A., Poon, W. W., Potter, H., Quinn, J. F., Raj, A., Raskind, M., Reiman, E. M., Reisberg, B., Ringman, J. M., Roberson, E. D., Sano, M., Saykin, A. J., Schneider, J. A., Schneider, L. S., Seeley, W. W., Smith, A. G., Sonnen, J. A., Spina, S., Stern, R. A., Tanzi, R. E., Trojanowski, J. Q., Troncoso, J. C., Tsuang, D. W., Van Deerlin, V. M., Van Eldik, L. J., Vinters, H. V., Vonsattel, J. P., Weintraub, S., Welsh-Bohmer, K. A., Williamson, J., Woltjer, R. L., Wright, C. B., Younkin, S. G., Yu, C. E. & Yu, L., Nov 2015, In: JAMA Neurology. 72, 11, p. 1313-1323 11 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    29 Scopus citations
  • Associations between Potentially Modifiable Risk Factors and Alzheimer Disease: A Mendelian Randomization Study

    Jun 1 2015, In: PLoS Medicine. 12, 6, e1001841.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    126 Scopus citations
  • Discrimination of mild cognitive impairment and alzheimer's disease using transfer entropy measures of scalp EEG

    McBride, J., Zhao, X., Munro, N., Jicha, G., Smith, C. & Jiang, Y., Mar 1 2015, In: Journal of Healthcare Engineering. 6, 1, p. 55-70 16 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    24 Scopus citations
  • Ferritin levels in the cerebrospinal fluid predict Alzheimer's disease outcomes and are regulated by APOE

    Department of Genetics University of North Carolina, May 19 2015, In: Nature Communications. 6, 6760.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    188 Scopus citations
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