Personal profile
Research Interests
Design and analysis of early phase clinical trials focusing on Bayesian design and interim monitoring. Statistical analysis of transgenic, xenograft and chemically induced mouse models of cancer.
Education/Academic qualification
Post Doctoral Fellow, University Of Alabama-University College
1994
Doctor of Philosophy, University Of South Carolina
1993
Master of Science, Louisiana State University
1989
Bachelor of Science, University Of The Philippines
1985
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being
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Collaborations and top research areas from the last five years
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Targeting Lung Fibrosis Using Epigenetic Therapy
Brainson, C. (PI), Allison, D. (CoI), Beswick, E. (CoI), Liu, J. (CoI), Sturgill, J. (CoI), Weiss, H. (CoI) & Waters, C. (Former CoI)
National Heart Lung and Blood Institute
8/15/24 → 7/31/28
Project: Research project
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FY26 UK/UL Joint Program Inherited Cancer Risk Program
D'Orazio, J. (PI), Allison, D. (CoI), Durbin, E. B. (CoI), Harrington, A. (CoI), Jeong, J. C. (CoI), Shelman, N. (CoI), Weiss, H. (CoI) & Zhang, S. (CoI)
KY Cabinet for Health and Family Services
7/1/24 → 6/30/26
Project: Research project
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FY26 DNA-PK Inhibition in Neuroblastoma
Rellinger, E. (PI), Weiss, H. (CoI) & Rychahou, P. (CoPI)
KY Cabinet for Health and Family Services
7/1/24 → 6/30/26
Project: Research project
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Targeting the Immunosuppressive Tumor Microenvironment for Colorectal Cancer Treatment
Wang, Q. (PI), Bondada, S. (CoI), Higashi, R. (CoI), Lee, E. (CoI), Wang, C. (CoI), Weiss, H. (CoI) & Evers, B. M. (CoPI)
9/1/23 → 8/31/28
Project: Research project
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PRiMAL: Pragmatic Randomized Clinical Trial Comparing MTB Assisted Care to Usual Care
Mullett, T. (PI), Arnold, S. M. (CoI), Huang, B. (CoI), Hull, P. (CoI), McLouth, L. (CoI), Weiss, H. (CoI), Westgate, P. (CoI) & Kolesar, J. (Former PI)
9/2/22 → 11/7/26
Project: Research project
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Cancer-associated fibroblast secreted DKK1 promotes the immunosuppressive tumor microenvironment and colorectal cancer resistance to chemotherapy
Yin, Z., Zhou, Y., Zhu, X., Goettl, R. A., Wang, C., Weiss, H. L., Evers, B. M. & Wang, Q., Dec 1 2025, In: Cancer Letters. 634, 218060.Research output: Contribution to journal › Article › peer-review
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Extracellular vesicles released by ALL patients contain HNE-adducted proteins: Implications of collateral damage
Ho, J., Sukati, S., Taylor, T., Carter, S., Fuller, B., Marmo, A., Sorge, C., D'Orazio, J., Butterfield, D. A., Bondada, S., Weiss, H., St Clair, D. K. & Chaiswing, L., Feb 1 2025, In: Free Radical Biology and Medicine. 227, p. 312-321 10 p.Research output: Contribution to journal › Article › peer-review
Open Access -
miR-181a-5p mediates the effects of BMP4 on intestinal cell proliferation and differentiation
Li, C., Zhou, Y., Yin, Z., Jiang, Y., Liu, J., Weiss, H. L., Wang, Q. & Evers, B. M., Dec 2025, In: Cell Death and Disease. 16, 1, 420.Research output: Contribution to journal › Article › peer-review
Open Access -
miR-27a-3p regulates intestinal cell proliferation and differentiation through Wnt/β-catenin signalling
Li, C., Zhou, Y., Jiang, Y., Yin, Z., Weiss, H. L., Wang, Q. & Evers, B. M., Feb 2025, In: Cell Proliferation. 58, 2, e13757.Research output: Contribution to journal › Article › peer-review
Open Access7 Scopus citations -
Neurotensin inhibits AMPK activity and concurrently enhances FABP1 expression in small intestinal epithelial cells associated with obesity and aging
Li, J., Song, J., Yan, B., Wu, H., Banerjee, M., Magnuson, L., Liu, Y., Zhang, S., Liu, J., Wang, C., Gao, T., Jia, J., Weiss, H. L. & Evers, B. M., Jun 2025, In: Experimental and Molecular Medicine. 57, 6, p. 1189-1201 13 p.Research output: Contribution to journal › Article › peer-review
Open Access