Projects and Grants per year
Personal profile
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
Doctor of Philosophy, University Of Kentucky
2014
Master of Science, University Of Kentucky
2009
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Dive into the research topics where Houfu Guo is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Collaborations and top research areas from the last five years
Recent external collaboration from the last 5 years on country level. Dive into details by clicking on the dots.
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Determine How Collagen Lysyl Hydroxylase 2 Drives Metastasis
Guo, H. (PI), Chen, L. (CoI) & Wang, C. (CoI)
1/1/25 → 12/31/28
Project: Research project
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Mechanistic and structural insights into a new pro-metastatic collagen glucosyltransferase
Guo, H. (PI), Brainson, C. (CoI) & Chen, L. (CoI)
1/16/24 → 12/31/28
Project: Research project
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The PLOD2/Succinate Axis in Cancer Cell Plasticity and Stemness
Xu, R. (PI), Bocklage, T. (CoI), Chen, L. (CoI) & Guo, H. (CoI)
9/1/23 → 8/31/28
Project: Research project
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Pilot: The Role Of Collagen Glycosylation In Prometastatic Signaling And Metabolic Reprogramming
Guo, H. (PI)
National Institute of General Medical Sciences
6/15/22 → 12/31/22
Project: Research project
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Determining Structural Features of a Collagen Lysyl Hydroxylase that Promotes Lung Cancer Metastasis
Guo, H. (PI)
9/11/20 → 8/31/23
Project: Research project
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Computational Investigation of a Series of Small Molecules as Potential Compounds for Lysyl Hydroxylase-2 (LH2) Inhibition
Maghsoud, Y., Vázquez-Montelongo, E. A., Yang, X., Liu, C., Jing, Z., Lee, J., Harger, M., Smith, A. K., Espinoza, M., Guo, H. F., Kurie, J. M., Dalby, K. N., Ren, P. & Cisneros, G. A., Feb 13 2023, In: Journal of Chemical Information and Modeling. 63, 3, p. 986-1001 16 p.Research output: Contribution to journal › Article › peer-review
Open Access7 Scopus citations -
Unleashing the Potential of 1,3-Diketone Analogues as Selective LH2 Inhibitors
Lee, J., Guo, H. F., Wang, S., Maghsoud, Y., Vázquez-Montelongo, E. A., Jing, Z., Sammons, R. M., Cho, E. J., Ren, P., Cisneros, G. A., Kurie, J. M. & Dalby, K. N., Oct 12 2023, In: ACS Medicinal Chemistry Letters. 14, 10, p. 1396-1403 8 p.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
Comparative genomic and biochemical analyses identify a collagen galactosylhydroxylysyl glucosyltransferase from Acanthamoeba polyphaga mimivirus
Wu, W., Kim, J. S., Bailey, A. O., Russell, W. K., Richards, S. J., Chen, T., Chen, T., Chen, Z., Liang, B., Yamauchi, M. & Guo, H., Dec 2022, In: Scientific Reports. 12, 1, 16806.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Lysyl hydroxylase 2 mediated collagen post-translational modifications and functional outcomes
Terajima, M., Taga, Y., Nakamura, T., Guo, H. F., Kayashima, Y., Maeda-Smithies, N., Parag-Sharma, K., Kim, J. S., Amelio, A. L., Mizuno, K., Kurie, J. M. & Yamauchi, M., Dec 2022, In: Scientific Reports. 12, 1, 14256.Research output: Contribution to journal › Article › peer-review
Open Access15 Scopus citations -
A collagen glucosyltransferase drives lung adenocarcinoma progression in mice
Guo, H. F., Bota-Rabassedas, N., Terajima, M., Leticia Rodriguez, B., Gibbons, D. L., Chen, Y., Banerjee, P., Tsai, C. L., Tan, X., Liu, X., Yu, J., Tokmina-Roszyk, M., Stawikowska, R., Fields, G. B., Miller, M. D., Wang, X., Lee, J., Dalby, K. N., Creighton, C. J. & Phillips, G. N. & 3 others, , Dec 2021, In: Communications Biology. 4, 1, 482.Research output: Contribution to journal › Article › peer-review
Open Access17 Scopus citations