Projects and Grants per year
Personal profile
Education/Academic qualification
Doctor of Philosophy, University Of Kentucky
2014
Master of Science, University Of Kentucky
2009
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being
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Dive into the research topics where Houfu Guo is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Collaborations and top research areas from the last five years
Recent external collaboration from the last 5 years on country level. Dive into details by clicking on the dots.
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Determine How Collagen Lysyl Hydroxylase 2 Drives Metastasis
Guo, H. (PI), Chen, L. (CoI) & Wang, C. (CoI)
1/1/25 → 12/31/28
Project: Research project
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Mechanistic and structural insights into a new pro-metastatic collagen glucosyltransferase
Guo, H. (PI), Brainson, C. (CoI) & Chen, L. (CoI)
1/16/24 → 12/31/28
Project: Research project
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Targeting PLOD2 in Undifferentiated Pleomorphic Sarcoma
Guo, H. (PI)
3/1/26 → 8/31/26
Project: Research project
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The PLOD2/Succinate Axis in Cancer Cell Plasticity and Stemness
Xu, R. (PI), Bocklage, T. (CoI), Chen, L. (CoI) & Guo, H. (CoI)
9/1/23 → 10/17/25
Project: Research project
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Pilot: The Role Of Collagen Glycosylation In Prometastatic Signaling And Metabolic Reprogramming
Guo, H. (PI)
National Institute of General Medical Sciences
6/15/22 → 12/31/22
Project: Research project
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Cloning, expression, and characterization of collagen galactosyltransferases from human, sponge, and sea walnut
Kim, J. S., Chen, T., Zhang, B., Miller, T. M., Gilliam, M. E. & Guo, H., May 2025, In: Protein Expression and Purification. 229, 106685.Research output: Contribution to journal › Article › peer-review
Open Access -
Lysyl hydroxylase 2 glucosylates collagen VI to drive lung cancer progression
Wang, S., Guo, H., Fukushima, R., Terajima, M., Liu, M., Xiao, G. Y., Koudelková, L., Wu, C., Liu, X., Yu, J., Burris, E., Xu, J., Schiavinato, A., Russell, W. K., Yamauchi, M., Tan, X. & Kurie, J. M., Apr 1 2025, In: Journal of Clinical Investigation. 135, 7, e189197.Research output: Contribution to journal › Article › peer-review
Open Access -
Structural basis of collagen glucosyltransferase function and its serendipitous role in kojibiose synthesis
Kim, J. S., Chen, Z., Espinosa Garcia, S. A., Buhlheller, C., Zhang, B., Richards, S. J., Chen, T., Wu, J., Bruntz, R. C., Gilliam, M. E., Yamauchi, M., Liang, B. & Guo, H., Dec 2025, In: Nature Communications. 16, 1, 6704.Research output: Contribution to journal › Article › peer-review
Open Access -
Structure of an Fe2+-binding-deficient mimiviral collagen lysyl hydroxylase
Chen, T., Buhlheller, C. & Guo, H., Jun 1 2025, In: Acta Crystallographica Section F:Structural Biology Communications. 81, Pt 6, p. 235-240 6 p.Research output: Contribution to journal › Article › peer-review
Open Access -
The Crystal Structure of Acanthamoeba Polyphaga Mimivirus R655 and Its Potential Glycosaminoglycan Glycosyltransferase Activity
Kim, J. S., Zhang, B., Morin, K. H., Gilliam, M. & Guo, H., Jul 1 2025, In: Biochemistry. 64, 13, p. 2737-2744 8 p.Research output: Contribution to journal › Article › peer-review
Open Access