James Badgett - Projects & Grants - University of Kentucky

57 Active
94 Finished

1 - 50 out of 151 results

Active

COGAAll2131 An International Pilot Study of Chemotherapy and Tyrosine Kinase Inhibitors with Blinatumomab in Patients with Newly-Diagnosed Philadelphia Chromosome-Positive or ABL-class Philadelphia Chromosome-Like B-Cell Acute Lymphoblastic Leukemia
Badgett, J. (PI)
7/3/25 → 2/28/26
Project: Research project
CHILDREN#S ONCOLOGY GROUP AREN2231 02/20/2025 Risk Adapted Treatment of Unilateral Favorable Histology Wilms Tumors (FHWT) A COG Groupwide Phase 3 Study Study Exempt from IND Requirements per 21 CFR 312.2(b)
Badgett, J. (PI)
Public Health Institute
5/15/25 → 5/15/35
Project: Research project
COG ACCL2031 A Phase 3 Randomized, Placebo-Controlled Trial Evaluating Memantine (IND# 149832) for Neurocognitive Protection in Children Undergoing Cranial Radiotherapy as Part of Treatment for Primary Central Nervous System Tumors A COG Groupwide Phase 3
Badgett, J. (PI)
Public Health Institute
3/1/25 → 3/1/35
Project: Research project
Walking Juntos: Developing and Testing a Culturally-Tailored Mobile Health and Social Media Physical Activity Intervention Among Adolescent and Young Adult Childhood Cancer Survivors
Badgett, J. (PI)
Public Health Institute
1/31/25 → 1/31/35
Project: Research project
AALL2121: A Phase 2 Study of SNDX-5613 in Combination with Chemotherapy for Patients with Relapsed or Refractory KMT2A-Rearranged Infant Leukemia
Badgett, J. (PI)
Public Health Institute
8/1/24 → 2/28/26
Project: Research project
FY25 Artesunate as Treatment for Childhood Acute Myeloid Leukemia C4935
Richards, C. (PI), Badgett, J. (CoI), Hill, K. (CoI), Ji, H. (CoI) & Yuan, L. (CoI)
KY Cabinet for Health and Family Services
7/1/24 → 6/30/26
Project: Research project
FY26 Macrophage Derived Engineered Vesicles to Treat Pediatric Osteosarcoma
Richards, C. (PI) & Badgett, J. (CoI)
KY Cabinet for Health and Family Services
7/1/24 → 6/30/26
Project: Research project
ANBL2131: A Phase 3 Study of Dinutuximab Added to Intensive Multimodal Therapy for Children with Newly Diagnosed High-Risk Neuroblastoma
Badgett, J. (PI)
Public Health Institute
5/15/24 → 2/28/26
Project: Research project
ACCL1931: Randomized Trial of Levocarnitine Prophylaxis to Prevent Asparaginase-Associated Hepatotoxicity in Adolescents and Young Adults Receiving Acute Lymphoblastic Leukemia Therapy
Badgett, J. (PI)
Public Health Institute
1/18/24 → 2/28/26
Project: Research project
Neuroblastoma Maintenance Therapy Trial Using Difluoromethylornithine (DFMO)
Badgett, J. (PI)
Pennsylvania State University
9/4/23 → 10/30/25
Project: Research project
BCC016: Phase II Trial of Eflornithine/DFMO as Maintenance Therapy for Molecular High Risk/Very High Risk and Relapsed/Refractory Medulloblastoma
Badgett, J. (PI)
Pennsylvania State University
9/1/23 → 7/16/26
Project: Research project
ACNS2021 A Phase 2 Trial of Chemotherapy Followed by Response-Based Whole Ventricular & Spinal Canal Irradiation (WVSCI) for Patients with Localized Non-Germinomatous Central Nervous System Germ Cell Tumor
Badgett, J. (PI)
Public Health Institute
8/4/23 → 2/28/26
Project: Research project
2021 Amazon High-Impact Initiative
Badgett, J. (PI)
Childrens Oncology Group Foundation Incorporated
7/13/23 → 7/13/25
Project: Research project
(BIQSFP for ACNS1831) A Phase 3 Randomized Study of Selumetinib (IND # 77782) versus Carboplatin/Vincristine in Newly Diagnosed or Previously Untreated Neurofibromatosis Type 1 (NF1) Associated Low-Grade Glioma (LGG)
Badgett, J. (PI)
Public Health Institute
3/1/23 → 2/28/26
Project: Research project
AOST2032 Supplemental Per Case Reimbursement (Feasibility Phase)
Badgett, J. (PI)
Public Health Institute
8/21/22 → 8/30/25
Project: Research project
A Phase 3 Randomized Study of Selumetinib (IND#77782) versus Carboplatin/Vincristine in Newly Diagnosed or Previously Untreated Neurofibromatosis Type 1 (NF1) Associated Low-Grade Glioma (LGG)
Badgett, J. (PI)
Public Health Institute
7/1/22 → 4/30/27
Project: Research project
APAL2020SC: Pediatric Acute Leukemia (PedAL) Screening Trial # Developing New Therapies for Relapsed Leukemias
Badgett, J. (PI)
Public Health Institute
3/22/22 → 3/22/26
Project: Research project
St. Baldrick's Foundation Supplement Per Case Reimbursement
Badgett, J. (PI), Radulescu, V. (Former PI) & Wagner, L. (Former PI)
Childrens Oncology Group Foundation Incorporated
1/1/22 → 12/31/25
Project: Research project
AREN1921: Treatment of Newly Diagnosed Diffuse Anaplastic Wilms Tumors (DAWT) and Relapsed Favorable Histology Wilms Tumors (FHWT)
Badgett, J. (PI)
Public Health Institute
12/16/21 → 10/12/25
Project: Research project
ANHL1931: A Randomized Phase 3 trial of Nivolumab (NSC# 748726 IND# 125462) in Combination with Chemo-immunotherapy for the Treatment of Newly Diagnosed Primary Mediastinal B-cell Lymphoma
Badgett, J. (PI)
Public Health Institute
12/16/21 → 2/28/26
Project: Research project
AHOD1331: Cost Effectivess Analysis (CEA) of Brentuximab Vedotin in Newly Diagnosed High-Risk Classical Hodgkin Lymphoma (cHL) in Children and Adolescents
Badgett, J. (PI), Radulescu, V. (Former PI) & Wagner, L. (Former PI)
Public Health Institute
5/15/21 → 10/13/25
Project: Research project
AALL1331: Risk-Stratified Randomized Phase III Testing of Blinatumomab in First Relapse of Childhood B-Lymphoblastic Leukemia
Badgett, J. (PI), Radulescu, V. (Former PI) & Wagner, L. (Former PI)
Public Health Institute
5/15/21 → 8/30/25
Project: Research project
AGCT1532: Phase 3 Accelerated BEP Trial: A Randomised Phase 3 Trial of Accelerated Versus Standard BEP Chemotherapy for Patients with Intermediate and Poor-Risk Metastatic Germ Cell Tumours
Badgett, J. (PI)
Public Health Institute
5/1/21 → 9/7/25
Project: Research project
APEC1621I: NCI-COG Pediatric MATCH (Molecular Analysis for Therapy Choice) - Phase 2 Subprotocol of Palbociclib in Patients with Tumors Harboring Activating Alterations in Cell Cycle Genes
Badgett, J. (PI)
Public Health Institute
4/1/21 → 3/2/30
Project: Research project
Specimen Banking Supplements
Badgett, J. (PI)
Public Health Institute
3/29/21 → 2/28/26
Project: Research project
AAML1831: A Phase 3 Randomized Trial for Patients with De Novo AML Comparing Standard Therapy Including Gemtuzumab Ozogamicin (GO) to CPX-351 with GO, and the Addition of the FLT3 Inhibitor Gilteritinib for Patients with FLT3 Mutations
Badgett, J. (PI)
Public Health Institute
3/18/21 → 9/7/25
Project: Research project
ACNS1831: A Phase 3 Randomized Study of Selumetinib (IND #77782) Versus Carboplatin/Vincristine in Newly Diagnosed or Previously Untreated Neurofibromatosis Type 1 (NF1) Associated Low-Grade Glioma (LGG)
Badgett, J. (PI)
Public Health Institute
3/1/21 → 8/10/25
Project: Research project
ADHO2131: A Randomized Phase 3 Interim Response Adapted Trial Comparing Standard Therapy with Immuno-Oncology Therapy for Children and Adults with Newly Diagnosed Stage I and II Classic Hodgkin Lymphoma
Badgett, J. (PI)
Public Health Institute
3/1/21 → 2/28/26
Project: Research project
AOST2032, A Feasibility and Randomized Phase 2/3 Study of the VEFGR2/MET Inhibitor Cabozantinib in Combination with Cytotoxic Chemotherapy for Newly Diagnosed Osteosarcoma
Badgett, J. (PI)
Public Health Institute
3/1/21 → 2/28/26
Project: Research project
ANHL2121: Phase 2 Study of Tovorafenib (DAY101) in Relapsed and Refractory Langerhans Cell Histiocytosis
Badgett, J. (PI)
Public Health Institute
3/1/21 → 2/28/26
Project: Research project
ARST2032: A Prospective Phase 3 Study of Patients with Newly Diagnosed Very Low-risk and Low-risk Fusion Negative Rhabdomyosarcoma
Badgett, J. (PI)
Public Health Institute
3/1/21 → 2/28/26
Project: Research project
APEC1621 SC - NCI-COG Pediatric MATCH (Molecular Analysis for Therapy Choice) Screening Protocol
Badgett, J. (PI)
Public Health Institute
3/1/21 → 2/28/26
Project: Research project
AREN03B2: Renal Tumors Classification, Biology, and Banking Study
Badgett, J. (PI)
Public Health Institute
3/1/21 → 2/28/26
Project: Research project
NCTN Operations Grant U10CA180886 (Per Case Reimbursement)
Badgett, J. (PI), Radulescu, V. (Former PI) & Wagner, L. (Former PI)
Public Health Institute
3/1/21 → 2/28/26
Project: Research project
ACNS1931: A Phase 3 Study of Selumetinib
Badgett, J. (PI)
Public Health Institute
3/1/21 → 2/28/26
Project: Research project
NCORP Research Base Grant 2UG1CA189955-06 (Per Case Reimbursement)
Badgett, J. (PI), Radulescu, V. (Former PI) & Wagner, L. (Former PI)
Public Health Institute
3/1/21 → 7/31/25
Project: Research project
Blood Based Biomarkers for Minimal Residual Disease Detection in Pediatric Sarcomas
Badgett, J. (PI)
H Lee Moffitt Cancer Center and Research Institute Hospital
2/15/21 → 9/23/25
Project: Research project
AALL1821: A Phase 2 Study of Blinatumomab (NSC# 765986, IND# 125462) in Combination with Nivolumab (NSC# 748726, IND# 125462), a Checkpoint Inhibitor of PD-1, in B-ALL Patients Aged #1 to <30 Years Old with First Relapse
Badgett, J. (PI)
Public Health Institute
12/4/20 → 2/28/26
Project: Research project
AAML1831: A Phase 3 Randomized Trial for Patients with De Novo AML Comparing Standard Therapy Including Gemtuzumab Ozogamicin (GO) to CPX-351 with GO, and the Addition of the FLT3 Inhibitor Gilteritinib for Patients with FLT3 Mutations
Badgett, J. (PI)
Public Health Institute
7/20/20 → 9/7/25
Project: Research project
Mechanistic and Pharmacologic Studies of Selective Mithramycin Analogues Targeting EWS-FLI1 in Ewing Sarcoma
Tsodikov, O. (PI), Badgett, J. (CoI), Rohr, J. (CoPI), Leggas, M. (Former PI), Wang, C. (Former CoI) & Weiss, H. (Former CoI)
National Cancer Institute
6/1/20 → 5/31/26
Project: Research project
A Phase Ib/II Study to Evaluate the Safety, Feasibility and Efficacy of Nivolumab or Nivolumab in Combination with 5-Azacytidine in Patients with Recurrent, Resectable Osteosarcoma
Badgett, J. (PI)
H Lee Moffitt Cancer Center and Research Institute Hospital
1/21/20 → 8/3/25
Project: Research project
A Phase 3 Randomized Non-Inferiority Study of Carboplatin and Vincristine versus Selumetinib (NSC# 748727, IND# 77782) in Newly Diagnosed or Previously Untreated Low-Grade Glioma (LGG) not associated with BRAFV600E Mutations or Systemic Neurofibromatosis
Badgett, J. (PI)
Public Health Institute
1/3/20 → 2/28/26
Project: Research project
ALTE1631: Web-based Physical Activity Intervention for Children with ALL
Badgett, J. (PI) & Radulescu, V. (Former PI)
Public Health Institute
12/4/19 → 8/23/25
Project: Research project
Residual Scope: Web-based Physical Activity Intervention for Children with ALL
Badgett, J. (PI) & Radulescu, V. (Former PI)
Public Health Institute
12/4/19 → 8/23/25
Project: Research project
A Phase 3 Randomized Trial of Inotuzumab Ozogamicin (IND#:133494, NSC#: 772518) for Newly Diagnosed High-Risk B-ALL; Risk-Adapted Post-Induction Therapy for High-Risk B-ALL, Mixed Phenotype Acute Leukemia, and Disseminated B-LLy
Badgett, J. (PI)
Public Health Institute
10/28/19 → 10/12/25
Project: Research project
ACNS1831: A Phase 3 Randomized Study of Selumetinib (IND # 77782) versus Carboplatin/Vincristine in Newly Diagnosed or Previously Untreated Neurofibromatosis Type 1 (NF1) Associated Low-Grade Glioma (LGG)
Badgett, J. (PI)
Public Health Institute
10/4/19 → 8/10/25
Project: Research project
A Phase 2 Study of Inotuzumab Ozogamicin in Children and Young Adults with Relapsed or Refractory CD22+ B-Acute Lymphoblastic Leukemia (B-ALL)
Badgett, J. (PI) & Radulescu, V. (Former PI)
Public Health Institute
9/17/19 → 9/7/25
Project: Research project
ANBL1531: A Phase III Study of 131I Metaiodobenzylguanidine (131I-MIBG) or Crizotinib Added to Intensive Therapy for Children with Newly Diagnosed High-Risk Neuroblastoma (NBL)
Badgett, J. (PI) & Radulescu, V. (Former PI)
Public Health Institute
8/9/19 → 8/10/25
Project: Research project
A Phase 3 Trial Investigating Blinatumomab (IND# 117467, NSC# 765986) in Combination with Chemotherapy in Patients with Newly Diagnosed Standard Risk or Down syndrome B-Lymphoblastic Leukemia (B-ALL) and the Treatment of Patients with Localized B-Lymphobl
Badgett, J. (PI), Bayliff, S. (Former CoI), D'Orazio, J. (Former CoI), Geil, J. (Former CoI), Radulescu, V. (Former CoI), Shaw, A. (Former CoI) & Sorge, C. (Former CoI)
Public Health Institute
6/28/19 → 9/7/25
Project: Research project
Workload Intensity NIH Clinical Trials Network (NCTN) Grant
Badgett, J. (PI)
Public Health Institute
5/4/19 → 2/28/26
Project: Research project

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