James Badgett, MD

Atrium Health

7/17/23 → 7/16/25

Project: Research project

2021 Amazon High-Impact Initiative

Childrens Oncology Group Foundation Incorporated

7/13/23 → 7/13/25

Project: Research project

Validation of a Nanopore-Based Cell-Free DNA Assay for Accurate Diagnosis of ALL

Blackburn, J. & Badgett, J.

3/1/23 → 2/29/24

Project: Research project

Analysis and Targeting of the Transcriptional Regulator BRD4 in Diffuse Intrinsic Pontine Glioma (DIPG) (FY24)

Blackburn, J., Badgett, J., Chernyavskaya, Y., Glazer, E. & Havrylyuk, D.

7/1/22 → 6/30/24

Project: Research project

FY24 Artesunate as Treatment for Childhood Acute Myeloid Leukemia

Kolesar, J., Badgett, J., Hill, K., Ji, H. & Yuan, L.

7/1/22 → 6/30/24

Project: Research project

FY24 Project Inherited Cancer Risk

D'Orazio, J., Allison, D., Badgett, J., Durbin, E. B., Harrington, A., Jeong, J. C., Kolesar, J., Overley, C., Shelman, N., Weiss, H., Zhang, S. & Shaw, A.

7/1/22 → 6/30/24

Project: Research project

FY24 Macrophage Derived Engineered Vesicles for Preventing Metastases in Pediatric Osteosarcoma

Kolesar, J., Badgett, J. & Richards, C.

Childrens Oncology Group Foundation Incorporated

7/1/22 → 6/30/24

Project: Research project

Residual Scope: St. Baldrick's Foundation Supplement Per Case Reimbursement

Badgett, J., Radulescu, V. & Wagner, L.

1/1/22 → 12/31/23

Project: Research project

St. Baldrick's Foundation Supplement Per Case Reimbursement

Badgett, J., Radulescu, V. & Wagner, L.

Childrens Oncology Group Foundation Incorporated

1/1/22 → 12/31/23

Project: Research project

AREN1921: Treatment of Newly Diagnosed Diffuse Anaplastic Wilms Tumors (DAWT) and Relapsed Favorable Histology Wilms Tumors (FHWT)

12/16/21 → 10/12/23

Project: Research project

ANHL1931: A Randomized Phase 3 trial of Nivolumab (NSC# 748726 IND# 125462) in Combination with Chemo-immunotherapy for the Treatment of Newly Diagnosed Primary Mediastinal B-cell Lymphoma

12/16/21 → 12/7/23

Project: Research project

AHOD1331: Cost Effectivess Analysis (CEA) of Brentuximab Vedotin in Newly Diagnosed High-Risk Classical Hodgkin Lymphoma (cHL) in Children and Adolescents

Badgett, J., Radulescu, V. & Wagner, L.

5/15/21 → 10/13/23

Project: Research project

AALL1331: Risk-Stratified Randomized Phase III Testing of Blinatumomab in First Relapse of Childhood B-Lymphoblastic Leukemia

Badgett, J., Radulescu, V. & Wagner, L.

5/15/21 → 8/30/24

Project: Research project

AAML18P1: Stopping Tyrosine Kinase Inhibitors (TKI) to Assess Treatment-Free Remission (TFR) in Pediatric Chronic Myeloid Leukemia - Chronic Phase (CML-CP)

4/5/21 → 5/11/24

Project: Research project

APEC1621I: NCI-COG Pediatric MATCH (Molecular Analysis for Therapy Choice) - Phase 2 Subprotocol of Palbociclib in Patients with Tumors Harboring Activating Alterations in Cell Cycle Genes

4/1/21 → 3/2/30

Project: Research project

ANBL1821: A Phase 2 Randomized Study of Irinotecan/Temozolomide/Dinutuximab with or Without Eflornithine (DFMO) (IND# 141913) in Children with Relapsed, Refractory or Progressive Neuroblastoma

4/1/21 → 3/8/24

Project: Research project

Specimen Banking Supplements

3/29/21 → 2/28/25

Project: Research project

Specimen Banking Supplements

Childrens Hospital of Philadelphia

3/29/21 → 2/28/25

Project: Research project

AAML1831: A Phase 3 Randomized Trial for Patients with De Novo AML Comparing Standard Therapy Including Gemtuzumab Ozogamicin (GO) to CPX-351 with GO, and the Addition of the FLT3 Inhibitor Gilteritinib for Patients with FLT3 Mutations

3/18/21 → 9/7/24

Project: Research project

ANHL2121: Phase 2 Study of Tovorafenib (DAY101) in Relapsed and Refractory Langerhans Cell Histiocytosis

3/1/21 → 2/28/25

Project: Research project

ACNS1931: A Phase 3 Study of Selumetinib

3/1/21 → 2/28/25

Project: Research project

NCORP Research Base Grant 2UG1CA189955-06 (Per Case Reimbursement)

Badgett, J., Radulescu, V. & Wagner, L.

3/1/21 → 3/1/24

Project: Research project

ACNS1831: A Phase 3 Randomized Study of Selumetinib (IND #77782) Versus Carboplatin/Vincristine in Newly Diagnosed or Previously Untreated Neurofibromatosis Type 1 (NF1) Associated Low-Grade Glioma (LGG)

3/1/21 → 8/10/24

Project: Research project

AOST2031: A Phase 3 Randomized Controlled Trial Comparing Open vs Thoracoscopic Management of Pulmonary Metastases in Patients with Osteosarcoma

3/1/21 → 2/28/25

Project: Research project

AREN03B2: Renal Tumors Classification, Biology, and Banking Study

3/1/21 → 2/28/25

Project: Research project

ARST2032: A Prospective Phase 3 Study of Patients with Newly Diagnosed Very Low-risk and Low-risk Fusion Negative Rhabdomyosarcoma

3/1/21 → 2/28/25

Project: Research project

ACNS1821: A Phase 1/2 Trial of Selinexor (KPT-330) and Radiation Therapy in Newly-Diagnosed Pediatric Diffuse Intrinsic Pontine Glioma (DIPG) and High-Grade Glioma (HGG)

3/1/21 → 2/28/25

Project: Research project

ADHO2131: A Randomized Phase 3 Interim Response Adapted Trial Comparing Standard Therapy with Immuno-Oncology Therapy for Children and Adults with Newly Diagnosed Stage I and II Classic Hodgkin Lymphoma

3/1/21 → 2/28/25

Project: Research project

AOST2032, A Feasibility and Randomized Phase 2/3 Study of the VEFGR2/MET Inhibitor Cabozantinib in Combination with Cytotoxic Chemotherapy for Newly Diagnosed Osteosarcoma

3/1/21 → 2/28/25

Project: Research project

Neuroblastoma Maintenance Therapy Trial Using Difluoromethylornithine (DFMO)

Atrium Health

9/4/20 → 10/30/23

Project: Research project

AAML1831: A Phase 3 Randomized Trial for Patients with De Novo AML Comparing Standard Therapy Including Gemtuzumab Ozogamicin (GO) to CPX-351 with GO, and the Addition of the FLT3 Inhibitor Gilteritinib for Patients with FLT3 Mutations

7/20/20 → 9/7/24

Project: Research project

Risk-Stratified Therapy for Acute Myeloid Leukemia in Down Syndrome

National Cancer Institute

7/1/20 → 12/7/23

Project: Research project

Mechanistic and Pharmacologic Studies of Selective Mithramycin Analogues Targeting EWS-FLI1 in Ewing Sarcoma

Tsodikov, O., Badgett, J., Rohr, J., Leggas, M., Wang, C. & Weiss, H.

6/1/20 → 5/31/25

Project: Research project

A Phase Ib/II Study to Evaluate the Safety, Feasibility and Efficacy of Nivolumab or Nivolumab in Combination with 5-Azacytidine in Patients with Recurrent, Resectable Osteosarcoma

H Lee Moffitt Cancer Center and Research Institute Hospital

1/21/20 → 8/3/24

Project: Research project

A Phase 3 Randomized Non-Inferiority Study of Carboplatin and Vincristine versus Selumetinib (NSC# 748727, IND# 77782) in Newly Diagnosed or Previously Untreated Low-Grade Glioma (LGG) not associated with BRAFV600E Mutations or Systemic Neurofibromatosis

1/3/20 → 5/11/24

Project: Research project

ALTE1631: Web-based Physical Activity Intervention for Children with ALL

12/4/19 → 8/23/24

Project: Research project

Residual Scope: Web-based Physical Activity Intervention for Children with ALL

12/4/19 → 8/23/24

Project: Research project

A Phase 3 Randomized Trial of Inotuzumab Ozogamicin (IND#:133494, NSC#: 772518) for Newly Diagnosed High-Risk B-ALL; Risk-Adapted Post-Induction Therapy for High-Risk B-ALL, Mixed Phenotype Acute Leukemia, and Disseminated B-LLy

10/28/19 → 10/12/23

Project: Research project

LCH-IV: International Collaborative Treatment Protocol for Children and Adolescents with Langerhans Cell Histiocytosis

St Jude Childrens Research Hospital

10/17/19 → 4/9/24

Project: Research project

ACNS1831: A Phase 3 Randomized Study of Selumetinib (IND # 77782) versus Carboplatin/Vincristine in Newly Diagnosed or Previously Untreated Neurofibromatosis Type 1 (NF1) Associated Low-Grade Glioma (LGG)

10/4/19 → 8/10/24

Project: Research project

A Phase 2 Study of Dabrafenib (NSC# 763760) with Trametinib (NSC# 763093) after Local Irradiation in Newly-Diagnosed BRAFV600 -Mutant High-Grade Glioma (HGG) (IND# 145355)

10/2/19 → 11/10/23

Project: Research project

A Phase 2 Study of Inotuzumab Ozogamicin in Children and Young Adults with Relapsed or Refractory CD22+ B-Acute Lymphoblastic Leukemia (B-ALL)

9/17/19 → 9/7/24

Project: Research project

ANBL1531: A Phase III Study of 131I Metaiodobenzylguanidine (131I-MIBG) or Crizotinib Added to Intensive Therapy for Children with Newly Diagnosed High-Risk Neuroblastoma (NBL)

8/9/19 → 8/10/24

Project: Research project

A Phase 3 Trial Investigating Blinatumomab (IND# 117467, NSC# 765986) in Combination with Chemotherapy in Patients with Newly Diagnosed Standard Risk or Down syndrome B-Lymphoblastic Leukemia (B-ALL) and the Treatment of Patients with Localized B-Lymphobl

Badgett, J., Bayliff, S., D'Orazio, J., Geil, J., Radulescu, V., Shaw, A. & Sorge, C.

6/28/19 → 9/7/24

Project: Research project

Workload Intensity NIH Clinical Trials Network (NCTN) Grant

5/4/19 → 3/1/24

Project: Research project

AALL0434: Intensified Methotrexate, Nelarabine (Compound 506U78; NCI IND #52611) and Augmented BFM Therapy for Children and Young Adults with Newly Diagnosed T-cell Acute Lymphoblastic Leukemia ALL) or T-cell Lymphoblastic Lymphoma

11/28/18 → 8/30/24

Project: Research project

ALTE15N2, LEAHRN (Late Effects After High-Risk Neuroblastoma) Study

Badgett, J., Radulescu, V. & Wagner, L.

11/17/17 → 11/1/23

Project: Research project

A Phase III Randomized Trial for Patients with de novo AML Using Bortezomib and Sorafenib for Patients with High Allelic Ratio FLT3/ITD

Badgett, J., Radulescu, V. & Wagner, L.

3/31/17 → 5/2/24

Project: Research project

A Phase 2 Study of the JAK1/JAK2 Inhibitor Ruxolitinib with Chemotherapy in Children with De Novo High-Risk CRLLF2-Rearranged and/or JAK Pathway-Mutant Acute Lymphoblastic Leukemia AALL1521

Badgett, J., Radulescu, V. & Wagner, L.