Projects and Grants per year
Personal profile
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
Doctor of Philosophy, Oregon Health Sciences University
2008
Bachelor of Arts, University Of Rochester
1997
Bachelor of Science, University Of Rochester
1997
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Dive into the research topics where James Brien is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Collaborations and top research areas from the last five years
Recent external collaboration from the last 5 years on country level. Dive into details by clicking on the dots.
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mRNA-Based Vaccines Against Tick Borne Thogotoviruses
Brien, J. (PI)
Washington University in St. Louis
3/1/25 → 2/28/27
Project: Research project
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Encoding Immune-Modulation Within mRNA Vaccines Against the Model Flavivirus, West Nile Virus
Brien, J. (PI)
Merck Sharp & Dohme Corporation
12/17/24 → 12/16/26
Project: Research project
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IPA: Durability and Mechanisms of Dengue Vaccine and Infection Mediated Immunity
Brien, J. (PI)
4/1/24 → 3/31/26
Project: Research project
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Evaluation of Antibody Responses Elicited by Zika Vaccination in Flavivirus-Naive and -Experienced Individuals
Brien, J. (PI) & Pinto, A. (CoI)
Henry M Jackson Foundation for the Advancement of Military Medicine Incorporated
4/1/24 → 3/31/27
Project: Research project
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Dengue Virus mRNA Lipid Nanoparticle Vaccine
Pinto, A. (PI) & Brien, J. (CoI)
University of Illinois at Chicago
12/1/23 → 7/31/26
Project: Research project
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CD4+ T Cells Are Key to Shaping a Protective Humoral Immunity in Primary Dengue 2 Virus Infection: Implications for Rational Vaccine Design
Miranda-Santiago, A. E., Serrano-Collazo, C., Cruz, L. A., Henein, S., Alvarez, L., Arana, T., Sánchez-Bibiloni, J. L., Martinez, M. I., Roman, C., Burgos, A. G., Ramos-Benitez, M. J., Caro-Rivera, L. M., Brien, J. D., Pinto, A. K., de Silva, A. M. & Sariol, C. A., Nov 2025, In: Vaccines. 13, 11, 1103.Research output: Contribution to journal › Article › peer-review
Open Access -
DDO-adjuvanted influenza A virus nucleoprotein mRNA vaccine induces robust humoral and cellular type 1 immune responses and protects mice from challenge
Gnazzo, V., Saleh, H., Castro, Í. A., Boon, A. C. M., Pinto, A. K., Brien, J. D. & López, C. B., Feb 2025, In: mBio. 16, 2Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
The TLR7/8 agonist INI-4001 enhances the immunogenicity of a Powassan virus-like-particle vaccine
Crawford, M. W., Abdelwahab, W. M., Siram, K., Parkins, C. J., Harrison, H. F., Stone, E. T., Osman, S. R., Schweitzer, D., Burkhart, D. J., Pinto, A., Brien, J. D., Smith, J. L. & Hirsch, A. J., Dec 2025, In: npj Vaccines. 10, 1, 156.Research output: Contribution to journal › Article › peer-review
1 Scopus citations -
COVID-19 point-of-care tests can identify low-antibody individuals: In-depth immunoanalysis of boosting benefits in a healthy cohort
Mallory, M., Munt, J. E., Narowski, T. M., Castillo, I., Cuadra, E., Pisanic, N., Fields, P., Powers, J. M., Dickson, A., Harris, R., Wargowsky, R., Moran, S., Allabban, A., Raphel, K., McCaffrey, T. A., Brien, J. D., Heaney, C. D., Lafleur, J. E., Baric, R. S. & Premkumar, L., Jun 2024, In: Science advances. 10, 24, eadi1379.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Dissecting the biophysical mechanisms of oleate hydratase association with membranes
Lathram, W. A., Neff, R. J., Zalla, A. N., Brien, J. D., Subramanian, V. & Radka, C. D., 2024, In: Frontiers in Molecular Biosciences. 11, 1504373.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations