Projects and Grants per year
Personal profile
Research Interests
- Therapy Resistance
- Cancer Immunotherapy
- Cancer Metabolism
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
Post Doctoral Fellow, Yale University
1992
Doctor of Medicine, FuDan University
1988
Doctor of Philosophy, FuDan University
1988
Bachelor of Science, FuDan University
1983
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Collaborations and top research areas from the last five years
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Integrative Targeted Therapy for Melanoma
Yang, J. (PI), Evers, B. M. (CoI), Ren, X. (CoI) & Yan, D. (CoI)
4/1/24 → 3/31/29
Project: Research project
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Novel Strategy to Augmenting Immunotherapy Against Melanoma
Yang, J. (PI), Ren, X. (CoI) & Yan, D. (CoI)
3/1/24 → 2/28/26
Project: Research project
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Targeting Elongation Factor-2 Kinase to Reinforce Melanoma Immunotherapy
1/1/19 → 9/30/20
Project: Research project
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Nucleus Accumbens-Associated Protein-1 in Melanoma Immunotherapy
Yang, J. (PI), Ren, X. (CoI) & Wu, J. (Former CoI)
7/3/18 → 11/30/24
Project: Research project
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Cabozantinib selectively induces proteasomal degradation of p53 somatic mutant Y220C and impedes tumor growth
Lv, F. L., Zhang, L., Ji, C., Peng, L., Zhu, M., Yang, S., Dong, S., Zhou, M., Guo, F., Li, Z., Wang, F., Chen, Y., Zhou, J., Ren, X., Shen, G., Yang, J. M., Li, B. & Zhang, Y., Feb 2025, In: Journal of Biological Chemistry. 301, 2, 108167.Research output: Contribution to journal › Article › peer-review
Open Access -
eEF-2K Deficiency Boosts the Virus-Specific Effector CD8+ T Cell Responses During Viral Infection
Wang, L., Song, B. S., Poojary, R., Xiong, X., Ren, X., Yang, J. M. & Song, J., Jan 2025, In: Viruses. 17, 1, 26.Research output: Contribution to journal › Article › peer-review
Open Access -
Identification of a Novel Substrate for eEF2K and the AURKA-SOX8 as the Related Pathway in TNBC
Wan, X., Gong, R., Zhao, X., Li, Y., Shan, T., Zhong, C., Zhu, R., Chen, Z., Jiang, S., He, L., Cao, S., Tian, S., Yang, J., Ye, N., Yi, W. & Cheng, Y., Apr 10 2025, In: Advanced Science. 12, 14, 2412985.Research output: Contribution to journal › Article › peer-review
Open Access -
Metabolic fitness of NAC1-deficient Tregs in the tumor microenvironment fuels tumor growth
Kumar, A., Das, J. K., Peng, H. Y., Wang, L., Ballard, D. J., Ren, Y., Xiong, X., Ren, X., Yang, J. M., de Figueiredo, P. & Song, J., Feb 24 2025, In: JCI insight. 10, 4, e186000.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Targeting of Tumoral NAC1 Mitigates Myeloid-Derived Suppressor Cell-Mediated Immunosuppression and Potentiates Anti-PD-1 Therapy in Ovarian Cancer
Dong, S., Ye, C., Li, B., Lv, F., Zhang, L., Yang, S., Wang, F., Zhu, M., Zhou, M., Guo, F., Li, Z., Peng, L., Ji, C., Lu, X., Cheng, Y., Ren, X., Chen, Y., Zhou, J., Yang, J. & Zhang, Y., Feb 3 2025, In: Cancer Immunology Research. 13, 2, p. 286-302 17 p.Research output: Contribution to journal › Article › peer-review