Projects and Grants per year
Personal profile
Research Interests
- Cancer, infectious disease, inflammation and regenerative medicine.
- Enzyme mechanism, engineering/evolution and synthetic applications.
- Lead/probe discovery and development.
- Natural products discovery and biosynthesis.
Education/Academic qualification
Doctor of Philosophy, University Of Minnesota
1993
Bachelor of Arts, Augsburg College
1986
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being
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SDG 14 Life Below Water
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Collaborations and top research areas from the last five years
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Novel Antibiotic Alternatives for the Treatment of Subclinical Rhodococcus Equi Pneumonia in Foals
Helmy, Y. A. (PI), Mahmoud, K. A. (CoI) & Thorson, J. (CoI)
4/1/26 → 3/31/28
Project: Research project
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Impact Of Dysbiotic And Symbiotic Catabolism Of Luminal Amino Acids On Intestinal Epithelial Barrier Function And Inflammation
Alam, M. (PI), Barrett, T. (CoI), Evers, B. M. (CoI), Fields, K. (CoI), Gao, T. (CoI), Goretsky, T. (CoI) & Thorson, J. (CoI)
National Institute Diabetes & Digestive & Kidney
9/20/23 → 8/31/26
Project: Research project
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Combination of SJ733 with Tafenoquine as a Possible 1 or 2 Dose Radical Cure for P. Vivax Malaria
Thorson, J. (PI), Guy, R. (Former PI) & Bush, H. (Former CoI)
9/12/23 → 9/30/26
Project: Research project
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Probiotic Nissle E. coli 1917 as antibiotic-alternative to combat antibiotic-resistant Campylobacter in the food chain
Helmy, Y. A. (PI), Messaoudi Powers, I. (CoI) & Thorson, J. (CoI)
National Institute of Food and Agriculture
8/1/23 → 7/31/26
Project: Research project
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Development of Actinomycetes-Derived Antimicrobial Compounds as Eco-Friendly Solutions for the Management of Plant and Food-Borne Pathogens
Mahmoud, K. A. (PI) & Thorson, J. (CoPI)
5/1/23 → 4/30/27
Project: Research project
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Phaeosphaeride A Isolated from an Endophytic Paraphoma spAlleviates ABCG2-mediated Resistance to Mitoxantrone in Breast Cancer Cells
Tavakkoli, A., Mortazavi, H., Iranshahi, M., Kalalinia, F., Jamialahmadi, K., Thorson, J. S., Shaaban, K. A. & Mosaffa, F., Jun 1 2026, In: Planta Medica. 92, 7, p. 746-755 10 p.Research output: Contribution to journal › Article › peer-review
1 Scopus citations -
Triethylamine-promoted regioselective divergent CN bond formation and/or cascade annulation of activated coumarins with primary amines: Structural insights and anticancer activity
Eliwa, E. M., Frese, M., Soltan, M. M., Abd-Ellatef, G. E. F., Ali, M. A. M., Chaudhary, A. A., Ponomareva, L. V., Thorson, J. S., Shaaban, K. A., Shaaban, M., Dembinski, R. & Sewald, N., Oct 5 2026, In: Journal of Molecular Structure. 1371, 146527.Research output: Contribution to journal › Article › peer-review
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Functional and Structural Studies on the Esperamicin Thioesterase and Progress toward Understanding Enediyne Core Biosynthesis
Hankore, E. D., Miller, M. D., Kosgei, A. J., Xu, W., Tan, K., Endres, M., Bhardwaj, M., Joachimiak, G., Joachimiak, A., Phillips, G. N., Thorson, J. S. & Van Lanen, S. G., Oct 24 2025, In: Journal of Natural Products. 88, 10, p. 2360-2371 12 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Preclinical Pharmacokinetic Evaluation of Mithramycin and Mithramycin SA Tryptophan-Conjugated Analog
Niloy, K. K., Horn, J., Bhuiyan, N. H., Shaaban, K. A., Bhosale, S. S., Prisinzano, T. E., Thorson, J. S., Rohr, J. & Leggas, M., Jun 2025, In: Pharmaceutics. 17, 6, 765.Research output: Contribution to journal › Article › peer-review
Open Access -
Tetracenomycin Aglycones Primarily Inhibit Cell Growth and Proliferation in Mammalian Cancer Cell Lines
Birdsall, K., Brako, A. B. S., Brown, C., Paige, K., West, A., Schwartz, N., Hecht, J., Brown, K. V., Thorson, J. S., Shaaban, K. A. & Nybo, S. E., Nov 2025, In: Applied Sciences (Switzerland). 15, 22, 11985.Research output: Contribution to journal › Article › peer-review
Open Access