Grants and Contracts per year
Personal profile
Research Interests
Our lab drives translational research that seeks to help patients who have heart failure. We use biophysical, biochemical, and computational techniques to bridge the scientific gaps between molecular, celllular, and organ-level function.
Our research is grounded in sarcomere-level mechanics and mathematical modeling but extends beyond the myofilaments to explore ventricular growth, organ-level function, whole-body hemodynamics, and myocardial recovery induced by ventricular unloading.
Courses Taught
PGY630 - Quantitative methods for biomedical sciences (Course director)
MD826 - Medical School: Cardiovascular system (Course director)
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
Post Doctoral Fellow, Univ Of Wisconsin-Madison
2003
Doctor of Philosophy, Univ Of Birmingham
1998
Bachelor of Arts, Univ Of Oxford
1993
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Network
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Impact of Dilated Cardiomyopathy Mutations on Cardiac Myosin Structure and Function
The Pennsylvania State University
12/15/22 → 11/30/26
Project: Research project
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Measuring and Modeling Atrial Mechanics in Health and Heart Failure
11/1/21 → 10/31/24
Project: Research project
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Building a Pediatric Healthy Heart Cell Atlas Across Ancestries
10/1/21 → 9/30/24
Project: Research project
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Length-Dependent Activation in Human Myocardium
Campbell, K., Birks, E. & Thompson, K.
National Heart Lung and Blood Institute
9/15/20 → 7/31/24
Project: Research project
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Dual Filament Control of Myocardial Power and Hemodynamics
8/25/20 → 7/31/24
Project: Research project
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Cardiac myosin motor deficits are associated with left ventricular dysfunction in human ischemic heart failure
Rasicci, D. V., Ge, J., Milburn, G. N., Wood, N. B., Pruznak, A. M., Lang, C. H., Previs, M. J., Campbell, K. S. & Yengo, C. M., Feb 1 2023, In: American Journal of Physiology - Heart and Circulatory Physiology. 324, 2, p. H198-H209Research output: Contribution to journal › Article › peer-review
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Computational analysis of ventricular mechanics in hypertrophic cardiomyopathy patients
Mojumder, J., Fan, L., Nguyen, T., Campbell, K. S., Wenk, J. F., Guccione, J. M., Abraham, T. & Lee, L. C., Dec 2023, In: Scientific Reports. 13, 1, 958.Research output: Contribution to journal › Article › peer-review
Open Access -
Sarcomere length affects Ca2+ sensitivity of contraction in ischemic but not non-ischemic myocardium
Tanner, B. C. W., Awinda, P. O., Agonias, K. B., Attili, S., Blair, C. A., Thompson, M. S., Walker, L. A., Kampourakis, T. & Campbell, K. S., Mar 6 2023, In: Journal of General Physiology. 155, 3, e202213200.Research output: Contribution to journal › Article › peer-review
1 Scopus citations -
A multiscale model of the cardiovascular system that regulates arterial pressure via closed loop baroreflex control of chronotropism, cell-level contractility, and vascular tone
Sharifi, H., Mann, C. K., Wenk, J. F. & Campbell, K. S., Dec 2022, In: Biomechanics and Modeling in Mechanobiology. 21, 6, p. 1903-1917 15 p.Research output: Contribution to journal › Article › peer-review
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An expanding explanation for the ascending limb of muscle's active force-length relationship
Campbell, K. S., May 17 2022, In: Biophysical Journal. 121, 10, p. 1787-1788 2 p.Research output: Contribution to journal › Comment/debate