Grants and Contracts per year
Personal profile
Research Interests
Research in the Cassis laboratory focuses on the renin-angiotensin system in cardiovascular and metabolic diseases. This includes studies focused on hypertension, aortic aneurysmal disease, obesity and associated diseases, and COVID-19 in the context of the renin-angiotensin system. An area of emphasis is on biologic determinants of sex and how they influence the development and treatment of disease.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
Doctor of Philosophy, West Virginia University
1984
Bachelor of Science, West Virginia University
1980
Keywords
- RM Therapeutics. Pharmacology
- QP Physiology
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Network
Recent external collaboration from the last 5 years on country level. Dive into details by clicking on the dots.
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Training in Translational Research in Alzheimer's and Related Dementias (TRIAD)
Van Eldik, L., Cassis, L., Gerhardt, G., Saatman, K., Schoenberg, N., Spear, B., Webb, N. & Murphy, M.
8/1/22 → 7/31/27
Project: Research project
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KY EPSCoR Facilitation of Statewide Plan - Admin Cost FY22-23
7/1/22 → 6/30/24
Project: Research project
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Pharmacological Mechanistic Insights into Thoracic Aortic Aneurysm
Sheppard, M., Cassis, L., Daugherty, A. & Graf, G.
National Heart Lung and Blood Institute
12/18/20 → 11/30/25
Project: Research project
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A Novel Mechanism by which Smooth Muscle BMAL1 Regulates IL-6 and Sexual Dimorphism of Abdominal Aortic Aneurysm
Gong, M., Cassis, L. & Guo, Z.
National Heart Lung and Blood Institute
8/20/18 → 7/31/23
Project: Research project
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Adipocyte-Derived Serum Amyloid A Promotes Angiotensin II-Induced Abdominal Aortic Aneurysms in Obese C57BL/6J Mice
Shridas, P., Ji, A., Trumbauer, A. C., Noffsinger, V. P., Leung, S. W., Dugan, A. J., Thatcher, S. E., Cassis, L. A., De Beer, F. C., Webb, N. R. & Tannock, L. R., May 1 2022, In: Arteriosclerosis, Thrombosis, and Vascular Biology. 42, 5, p. 632-643 12 p.Research output: Contribution to journal › Article › peer-review
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Single-Cell Analysis of Aneurysmal Aortic Tissue in Patients with Marfan Syndrome Reveals Dysfunctional TGF-β Signaling
Dawson, A., Li, Y., Li, Y., Ren, P., Vasquez, H. G., Zhang, C., Rebello, K. R., Ageedi, W., Azares, A. R., Mattar, A. B., Sheppard, M. B., Lu, H. S., Coselli, J. S., Cassis, L. A., Daugherty, A., Shen, Y. H. & Lemaire, S. A., Jan 2022, In: Genes. 13, 1, 95.Research output: Contribution to journal › Article › peer-review
Open Access7 Scopus citations -
Tumor Suppressor Par-4 Regulates Complement Factor C3 and Obesity
Araujo, N., Sledziona, J., Noothi, S. K., Burikhanov, R., Hebbar, N., Ganguly, S., Shrestha-Bhattarai, T., Zhu, B., Katz, W. S., Zhang, Y., Taylor, B. S., Liu, J., Chen, L., Weiss, H. L., He, D., Wang, C., Morris, A. J., Cassis, L. A., Nikolova-Karakashian, M., Nagareddy, P. R., & 4 others, Mar 29 2022, In: Frontiers in Oncology. 12, 860446.Research output: Contribution to journal › Article › peer-review
Open Access -
Twenty Years of Studying AngII (Angiotensin II)-Induced Abdominal Aortic Pathologies in Mice: Continuing Questions and Challenges to Provide Insight into the Human Disease
Sawada, H., Lu, H. S., Cassis, L. A. & Daugherty, A., Mar 1 2022, In: Arteriosclerosis, Thrombosis, and Vascular Biology. 42, 3, p. 277-288 12 p.Research output: Contribution to journal › Review article › peer-review
Open Access6 Scopus citations -
Connecting Generations of Scientists in the Council on Hypertension Through Harriet Dustan
Watts, S. W., Alexander, B. T., Baylis, C., Brown, N. J., Cassis, L. A., Denton, K. M., Joe, B., Lerman, L. O., Oparil, S., Reckelhoff, J. F., Sandberg, K. & Touyz, R. M., Feb 1 2021, In: Hypertension. 77, 2, p. 296-307 12 p.Research output: Contribution to journal › Review article › peer-review
Open Access
Prizes
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Distinguished Lecturer, University of Mississippi
Cassis, Lisa (Recipient), 2019
Prize: Honorary award