Grants and Contracts per year
Personal profile
Research Interests
Research in the Cassis laboratory focuses on the renin-angiotensin system in cardiovascular and metabolic diseases. This includes studies focused on hypertension, aortic aneurysmal disease, obesity and associated diseases, and COVID-19 in the context of the renin-angiotensin system. An area of emphasis is on biologic determinants of sex and how they influence the development and treatment of disease.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
Doctor of Philosophy, West Virginia University
1984
Bachelor of Science, West Virginia University
1980
Keywords
- RM Therapeutics. Pharmacology
- QP Physiology
Fingerprint
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Collaborations and top research areas from the last five years
Recent external collaboration from the last 5 years on country level. Dive into details by clicking on the dots.
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The Serotonergic System in Periaortic Fat Regulates Regional Aortopathy Development
Cassis, L., Alsiraj, Y., Blalock, E., Loria Kinsey, A. & Nikolajczyk, B.
National Heart Lung and Blood Institute
8/1/23 → 7/31/27
Project: Research project
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Center for Appalachian Research in Environmental Sciences: Administrative Core
Hahn, E., Arnett, D., Bauer, J., Cassis, L., Christian, J., Cox, N., Curry, T., DiPaola, R., Dignan, M., Evers, B. M., Fan, W., Haynes, E., Hoover, A., Kern, P., May, B., Miller, J., Pearson, K., Pennell, K., Richardson, K., Sanderson, W., Schoenberg, N., Stanifer, S., Stanley, S., Stratton, T., Stromberg, A., Swanson, H., Talbert, J., Unrine, J. & Heath, E.
National Institute of Environmental Health Sciences
6/3/23 → 4/30/28
Project: Research project
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NRSA T32: Training in Translational Research in Alzheimer's and Related Dementias (TRIAD)
Van Eldik, L., Cassis, L., Gerhardt, G., Saatman, K., Schoenberg, N., Spear, B., Murphy, M. & Webb, N.
8/1/22 → 7/31/27
Project: Research project
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KY EPSCoR Facilitation of Statewide Plan - Admin Cost FY23-24
7/1/22 → 6/30/24
Project: Research project
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Aortic Stress Activates an Adaptive Program in Thoracic Aortic Smooth Muscle Cells That Maintains Aortic Strength and Protects Against Aneurysm and Dissection in Mice
Zhang, C., Li, Y., Chakraborty, A., Li, Y., Rebello, K. R., Ren, P., Luo, W., Zhang, L., Lu, H. S., Cassis, L. A., Coselli, J. S., Daugherty, A., Lemaire, S. A. & Shen, Y. H., Feb 1 2023, In: Arteriosclerosis, Thrombosis, and Vascular Biology. 43, 2, p. 234-252 19 p.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
Adipocyte-Derived Serum Amyloid A Promotes Angiotensin II-Induced Abdominal Aortic Aneurysms in Obese C57BL/6J Mice
Shridas, P., Ji, A., Trumbauer, A. C., Noffsinger, V. P., Leung, S. W., Dugan, A. J., Thatcher, S. E., Cassis, L. A., De Beer, F. C., Webb, N. R. & Tannock, L. R., May 1 2022, In: Arteriosclerosis, Thrombosis, and Vascular Biology. 42, 5, p. 632-643 12 p.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
Single-Cell Analysis of Aneurysmal Aortic Tissue in Patients with Marfan Syndrome Reveals Dysfunctional TGF-β Signaling
Dawson, A., Li, Y., Li, Y., Ren, P., Vasquez, H. G., Zhang, C., Rebello, K. R., Ageedi, W., Azares, A. R., Mattar, A. B., Sheppard, M. B., Lu, H. S., Coselli, J. S., Cassis, L. A., Daugherty, A., Shen, Y. H. & Lemaire, S. A., Jan 2022, In: Genes. 13, 1, 95.Research output: Contribution to journal › Article › peer-review
Open Access14 Scopus citations -
Tumor Suppressor Par-4 Regulates Complement Factor C3 and Obesity
Araujo, N., Sledziona, J., Noothi, S. K., Burikhanov, R., Hebbar, N., Ganguly, S., Shrestha-Bhattarai, T., Zhu, B., Katz, W. S., Zhang, Y., Taylor, B. S., Liu, J., Chen, L., Weiss, H. L., He, D., Wang, C., Morris, A. J., Cassis, L. A., Nikolova-Karakashian, M., Nagareddy, P. R., & 4 others, Mar 29 2022, In: Frontiers in Oncology. 12, 860446.Research output: Contribution to journal › Article › peer-review
Open Access -
Twenty Years of Studying AngII (Angiotensin II)-Induced Abdominal Aortic Pathologies in Mice: Continuing Questions and Challenges to Provide Insight into the Human Disease
Sawada, H., Lu, H. S., Cassis, L. A. & Daugherty, A., Mar 1 2022, In: Arteriosclerosis, Thrombosis, and Vascular Biology. 42, 3, p. 277-288 12 p.Research output: Contribution to journal › Review article › peer-review
Open Access14 Scopus citations
Prizes
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Harriet Dustan Excellence in Hypertension Research
Cassis, Lisa (Recipient), 2012
Prize: Honorary award
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