Projects and Grants per year
Personal profile
Research Interests
Shaddox main research interests are aimed at evaluating immunological, microbiological and genetic factors involved with localized aggressive periodontal disease in children and adolescents. Shaddox’s recent NIH R01 grant renewal is aimed at expanding this cohort to tease out possible genetic markers and specific inflammatory mechanisms playing a role in this disease.
She has also led a clinical research project to investigate the relationship between periodontal disease and type II diabetes mellitus and its inflammatory response to bacteria, and how this relationship is associated with diabetics’ clinical response to treatment.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
Doctor of Philosophy, State UniversityOf Campinas
2005
Master of Science, State UniversityOf Campinas
2003
Doctor of Dental Science, State UniversityOf Campinas
2001
External positions
NIDCR Study Section Member
2021 → 2024
AADR Fellow
2021 → …
Task Force for Design and Analysis in Dental and Oral Research Member
2021 → …
AADOCR Member at Large
Keywords
- RK Dentistry
- Periodontitis
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Collaborations and top research areas from the last five years
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Understanding the Association Between Sublingual Buprenorphine and Oral Health Outcomes
Rojas Ramirez, M. (PI), Adatorwovor, R. (CoI), Boggero, I. (CoI), Gonzalez Duque, O. (CoI), Lofwall, M. (CoI), Miller, C. (CoI), Moga, D. (CoI), Omami, G. (CoI), Shaddox, L. (CoI) & Oyler, D. (CoPI)
National Institute of Dental and Craniofacial Research
9/21/23 → 9/20/25
Project: Research project
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Initial Evidence for a Brief Psychological Telehealth Intervention for Patients with Chronic Masticatory Muscle Pain
Boggero, I. (PI), Adatorwovor, R. (CoI), Bush, M. (CoI), Moreno Hay, I. (CoI) & Shaddox, L. (CoI)
National Institute of Dental and Craniofacial Research
9/1/23 → 8/31/28
Project: Research project
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A Randomized Controlled Trial to Evaluate the Effectiveness of an HPV Vaccination Recommendation Delivered by Dental Providers Versus No Dental Provider HPV Vaccine Recommendation
Shaddox, L. (PI), Adatorwovor, R. (CoI), Stein, P. (CoI) & Stone, D. (Former CoI)
3/1/23 → 3/8/25
Project: Research project
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Susceptibility Patterns for Grade C Periodontitis in Young Individuals
Shaddox, L. (PI), Adatorwovor, R. (CoI), Hartsfield Jr, J. (CoI), Morford, L. (CoI), Moseley, H. (CoI), Santamaria, M. (CoI) & Talbert, J. (CoI)
National Institute of Dental and Craniofacial Research
9/22/22 → 8/31/27
Project: Research project
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Kentucky Center for Clinical and Translational Science
Kern, P. (PI), Adatorwovor, R. (CoI), Bauer, J. (CoI), Bumgardner, V. (CoI), Bush, M. (CoI), Bush, H. (CoI), Campbell, K. (CoI), Cassis, L. (CoI), Coker, A. (CoI), Conwell, D. (CoI), Curry, T. (CoI), Daugherty, A. (CoI), DiPaola, R. (CoI), Duncan, M. (CoI), Durbin, E. B. (CoI), Dutch, R. (CoI), Dwoskin, L. (CoI), Elam, C. (CoI), Ellingson, S. (CoI), Evers, B. M. (CoI), Feltner, F. (CoI), Fisher, S. (CoI), Fowlkes, J. (CoI), Garcia, A. (CoI), Goldstein, L. (CoI), Griffith, C. (CoI), Guy, R. K. (CoI), Harris, J. (CoI), Harris, D. (CoI), Hatton, K. (CoI), Haynes, E. (CoI), Hussain, R. (CoI), Jicha, G. (CoI), Jones, A. (CoI), Kelly, T. (CoI), King, V. (CoI), Kruse-Diehr, A. (CoI), Kryscio, R. (CoI), Lile, J. (CoI), Mahmoud, K. A. (CoI), Messaoudi Powers, I. (CoI), Moseley, H. (CoI), Mudd, G. (CoI), Noehren, B. (CoI), Prisinzano, T. (CoI), Roper, K. (CoI), Rush, C. (CoI), Sawaya, B. (CoI), Schoenberg, N. (CoI), Shaddox, L. (CoI), Sheppard, M. (CoI), Slade, E. (CoI), Smalls, B. (CoI), Stevens-Watkins, D. (CoI), Stoops, W. (CoI), Surratt, H. (CoI), Talbert, J. (CoI), Tannock, L. (CoI), Thompson, J. (CoI), Thorson, J. (CoI), Van Eldik, L. (CoI), Walsh, S. (CoI), Weiss, H. (CoI), Westgate, P. (CoI), Whitehurst, L. (CoI), Williams, L. (CoI), Zhang, X. (CoI), Hartmann, K. (CoPI), Burnett, C. (Former CoI), Cardarelli, K. (Former CoI), Chen, J. (Former CoI), Dugan, A. (Former CoI), Ebbert, M. T. W. (Former CoI), Gilbert, P. (Former CoI), Glasser, S. (Former CoI), Hahn, E. (Former CoI), Holloway, L. (Former CoI), Jacobs, N. (Former CoI), Kasarskis, E. (Former CoI), Kavuluru, R. (Former CoI), Li, J. (Former CoI), Malluche, H. (Former CoI), Newman, M. (Former CoI), Peterson, C. (Former CoI), Selwitz, A. (Former CoI), Truszczynski, M. (Former CoI), Waters, T. (Former CoI), Webb, N. (Former CoI), Williams, M. (Former CoI) & de Beer, F. (Former CoI)
National Center for Advancing Translational Sciences
8/15/16 → 6/30/26
Project: Research project
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Gender Differences in Barriers in Career Development Among a Cohort of Dental Researchers. A Cross-Sectional Study
Sangalli, L., Shaddox, L. M. & De Souza, G. M., 2025, (Accepted/In press) In: Journal of Dental Education.Research output: Contribution to journal › Article › peer-review
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Microbiome and Inflammatory Biomarkers Associated With Palatal Wound Healing
Santamaria, M. P., Mathias-Santamaria, I. F., Ferreira Bonafé, A. C., Gonzalez Duque, O., Kirakodu, S., Monteiro, M. D. F., Casarin, R. C. V., Shaddox, L. M. & Miguel, M. M. V., 2025, (Accepted/In press) In: Journal of Periodontal Research.Research output: Contribution to journal › Article › peer-review
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Association of RS1126478 (LTF) with molar-incisor and generalized periodontitis
Stolf, C. S., Pereira, A. G. S., Almeida, B. C., Paz, H. E. S., Arroteia, L. S., Huang, H., Aukhil, I., Harrison, P., Miguel, M. M. V., Ferraz, L. F. F., Santamaria, M. P., Shaddox, L. M. & Casarin, R. C. V., Dec 2024, In: Clinical Oral Investigations. 28, 12, 653.Research output: Contribution to journal › Article › peer-review
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Evaluation of microbiome in primary and permanent dentition in grade C periodontitis in young individuals
Koo, S. S., Fernandes, J. G., Li, L., Huang, H., Aukhil, I., Harrison, P., Diaz, P. I. & Shaddox, L. M., Jul 2024, In: Journal of Periodontology. 95, 7, p. 650-661 12 p.Research output: Contribution to journal › Article › peer-review
4 Scopus citations -
Grade C Molar-Incisor Pattern Periodontitis in Young Adults: What Have We Learned So Far?
Miguel, M. M. V. & Shaddox, L. M., Jul 2024, In: Pathogens. 13, 7, 580.Research output: Contribution to journal › Review article › peer-review
Open Access1 Scopus citations