Projects and Grants per year
Personal profile
Research Interests
Bioactive properties of sphingolipids.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
Doctor of Philosophy, Bulgarian Academy of Sciences, Institute of Biophysics, Sofia, Bulgaria
1992
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Dive into the research topics where Mariana Nikolova-Karakashian is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Collaborations and top research areas from the last five years
Recent external collaboration from the last 5 years on country level. Dive into details by clicking on the dots.
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Signaling and Metabolic Functions of nSMase-2 in Hepatic Steatosis and Onset of Insulin Resistance
Nikolova-Karakashian, M. (PI), Bieberich, E. (CoI) & Sullivan, P. (CoI)
National Institute Diabetes & Digestive & Kidney
9/1/23 → 8/31/25
Project: Research project
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Role of SMPDL3B in Obesity-Associated Non-Alcoholic Fatty Liver Disease
Wang, S. (PI), Lee, E. (CoI), Tong, S. (CoI), COHEN, D. (Former CoI) & Nikolova-Karakashian, M. (Former CoI)
National Institute Diabetes & Digestive & Kidney
7/1/22 → 4/30/27
Project: Research project
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Targeting Lipid Metabolism in Colorectal Cancer
Zaytseva, Y. (PI), Evers, B. M. (CoI), Lee, E. (CoI), Moseley, H. (CoI), Nikolova-Karakashian, M. (CoI), Rychahou, P. (CoI) & Weiss, H. (CoI)
4/1/21 → 3/31/26
Project: Research project
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Ceramide and Acute Phase Proteins Elevation During Aging
Nikolova-Karakashian, M. (PI), Bieberich, E. (CoI), McClintock, T. (CoI) & Wang, C. (CoI)
8/1/02 → 5/31/25
Project: Research project
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IPA: TBI-induced Exosome Release Accelerates Alzheimer#s Disease Pathology
Nikolova-Karakashian, M. (PI) & Bieberich, E. (CoI)
12/1/22 → 11/30/23
Project: Research project
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Ceramide-mediated orchestration of oxidative stress response through filopodia-derived small extracellular vesicles
Quadri, Z., Elsherbini, A., Crivelli, S. M., El-Amouri, S. S., Tripathi, P., Zhu, Z., Ren, X., Zhang, L., Spassieva, S. D., Nikolova-Karakashian, M. & Bieberich, E., Jul 2024, In: Journal of Extracellular Vesicles. 13, 7, e12477.Research output: Contribution to journal › Article › peer-review
Open Access4 Scopus citations -
Regulated translocation of neutral sphingomyelinase-2 to the plasma membrane drives insulin resistance in steatotic hepatocytes
El-Amouri, S., Karakashian, A., Bieberich, E. & Nikolova-Karakashian, M., Oct 2023, In: Journal of Lipid Research. 64, 10, 100435.Research output: Contribution to journal › Article › peer-review
Open Access5 Scopus citations -
Neutral Sphingomyelinase 2 Mediates Oxidative Stress Effects on Astrocyte Senescence and Synaptic Plasticity Transcripts
Zhu, Z., Quadri, Z., Crivelli, S. M., Elsherbini, A., Zhang, L., Tripathi, P., Qin, H., Roush, E., Spassieva, S. D., Nikolova-Karakashian, M., McClintock, T. S. & Bieberich, E., May 2022, In: Molecular Neurobiology. 59, 5, p. 3233-3253 21 p.Research output: Contribution to journal › Article › peer-review
Open Access10 Scopus citations -
Tumor Suppressor Par-4 Regulates Complement Factor C3 and Obesity
Araujo, N., Sledziona, J., Noothi, S. K., Burikhanov, R., Hebbar, N., Ganguly, S., Shrestha-Bhattarai, T., Zhu, B., Katz, W. S., Zhang, Y., Taylor, B. S., Liu, J., Chen, L., Weiss, H. L., He, D., Wang, C., Morris, A. J., Cassis, L. A., Nikolova-Karakashian, M. & Nagareddy, P. R. & 4 others, , Mar 29 2022, In: Frontiers in Oncology. 12, 860446.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
Methods to characterize synthesis and degradation of sphingomyelin at the plasma membrane and its impact on lipid raft dynamics
Nikolova-Karakashian, M., 2021, Methods in Molecular Biology. p. 113-129 17 p. (Methods in Molecular Biology; vol. 2187).Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review
7 Scopus citations