Grants and Contracts per year
Personal profile
Research Interests
Lung cancer invasion, metastasis and therapeutic resistance.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
Doctor of Philosophy, Univ Of Texas Medical
2011
Master of Science, Chinese Academy of Sciences
1997
Doctor of Medicine, Anhui Medical University
1992
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Collaborations and top research areas from the last five years
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Integrin alpha6beta4 Regulation of Cancer Epigenetics
O'Connor, K., Chen, M., Liu, J., Wang, C., Fondufe-Mittendorf, Y. & Hodges, K.
1/1/19 → 12/31/23
Project: Research project
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A Novel Peptide Suppresses Invasion and Metastasis in Rictor-amplified Lung Cancer
Army Medical Research and Materiel Command
7/1/21 → 6/30/23
Project: Research project
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Characterizing Metastatic Breast Cancer Heterogeneity Through Post-Mortem Tissue Collection
Stewart, R., Bocklage, T., Chambers, M., Chen, M., O'Connor, W. & Wang, C.
METAvivor Research and Support Incorporated
1/16/19 → 1/10/20
Project: Research project
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A Novel Peptide to Inhibit Rictor-amplified Lung Tumorigenesis
Yang, H., Arnold, S., Chen, M., Piecoro, D., Wang, C. & Wang, Q.
7/1/18 → 6/30/21
Project: Research project
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Acetylation of G3BP1 in Lung Cancer
Zhu, H., Brouxhon, S., Chen, M., Shi, Q. & Wang, C.
7/1/17 → 6/30/19
Project: Research project
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Integrin α6β4 requires plectin and vimentin for adhesion complex distribution and invasive growth
Qi, L., Knifley, T., Chen, M. & O’Connor, K. L., Jan 2022, In: Journal of Cell Science. 135, 2, 258471.Research output: Contribution to journal › Article › peer-review
Open Access5 Scopus citations -
Integrin α6β4 signals through DNA damage response pathway to sensitize breast cancer cells to cisplatin
Chen, M., Marrs, B., Qi, L., Knifley, T., Weiss, H. L., D’Orazio, J. A. & O’Connor, K. L., Nov 10 2022, In: Frontiers in Oncology. 12, 1043538.Research output: Contribution to journal › Article › peer-review
Open Access -
In vivo Tumor Growth and Spontaneous Metastasis Assays Using A549 Lung Cancer Cells
Qi, L., Knifley, T., Piecoro, D. W., Rychahou, P., Wu, J., O’Connor, K. L. & Chen, M., Apr 5 2020, In: Bio-protocol. 10, 7, e3579.Research output: Contribution to journal › Article › peer-review
Open Access3 Citations (SciVal) -
N-glycosylation-defective splice variants of neuropilin-1 promote metastasis by activating endosomal signals
Huang, X., Ye, Q., Chen, M., Li, A., Mi, W., Fang, Y., Zaytseva, Y. Y., O’Connor, K. L., Vander Kooi, C. W., Liu, S. & She, Q. B., Dec 1 2019, In: Nature Communications. 10, 1, 3708.Research output: Contribution to journal › Article › peer-review
Open Access31 Scopus citations -
S100A4 alters metabolism and promotes invasion of lung cancer cells by up-regulating mitochondrial complex i protein NDUFS2
Liu, L., Qi, L., Knifley, T., Piecoro, D. W., Rychahou, P., Liu, J., Mitov, M. I., Martin, J., Wang, C., Wu, J., Weiss, H. L., Butterfield, D. A., Evers, B. M., O'Connor, K. L. & Chen, M., May 3 2019, In: Journal of Biological Chemistry. 294, 18, p. 7516-7527 12 p.Research output: Contribution to journal › Article › peer-review
Open Access36 Scopus citations