Projects and Grants per year
Personal profile
Research Interests
Mechanistic studies of oncogenic transcription factors and their disruption in search for novel anti-cancer therapeutics.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
Doctor of Philosophy, University of Wisconsin-Marathon
1998
Fingerprint
- 1 Similar Profiles
Collaborations and top research areas from the last five years
-
Iron Independent Role for Yersiniabactin in Yersinia Pestis
Garneau-Tsodikova, S. (PI) & Tsodikov, O. (CoI)
6/4/21 → 5/31/27
Project: Research project
-
Mechanistic and Pharmacologic Studies of Selective Mithramycin Analogues Targeting EWS-FLI1 in Ewing Sarcoma
Tsodikov, O. (PI), Badgett, J. (CoI), Rohr, J. (CoPI), Leggas, M. (Former PI), Wang, C. (Former CoI) & Weiss, H. (Former CoI)
6/1/20 → 5/31/26
Project: Research project
-
Administrative Supplement: Mechanistic and Pharmacologic Studies of Selective Mithramycin Analogues Targeting EWS-FLI1 in Ewing Sarcoma
Tsodikov, O. (PI), Rohr, J. (CoI), Leggas, M. (Former PI) & Rivas, J. (Former CoI)
6/1/20 → 5/31/22
Project: Research project
-
Scope: Tsodikov: Mechanistic and Pharmacologic Studies of Selective Mithramycin Analogues Targeting EWS-FLI1 in Ewing Sarcoma
Tsodikov, O. (PI)
6/1/20 → 5/31/22
Project: Research project
-
Discovery and Development of Mithramycin Analogs for Prostate Cancer Treatment by Direct Inhibition of the Oncogenic Transcription Factor ERG (TMPRSS2-ERG)
Tsodikov, O. (PI)
8/15/16 → 8/14/20
Project: Research project
-
Crystal structures and low-affinity complex formation of halogenase CtcP and FAD reductase CtcQ from the chlortetracycline biosynthetic pathway
Hou, C., Garneau-Tsodikova, S. & Tsodikov, O. V., Jul 2025, In: Bioscience Reports. 45, 7, p. 1-14 14 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Development of Zafirlukast Analogues for Improved Antithrombotic Activity Through Thiol Isomerase Inhibition
Keovilay, J. A., Howard, K. C., Taylor, K. A., Khan, S., Wurl, S. E., Szahaj, M. K., Sage, T., Chandrika, N. T., Hou, C., Tsodikov, O. V., Gibbins, J. M., Garneau-Tsodikova, S. & Kennedy, D. R., Apr 1 2025, In: Arteriosclerosis, Thrombosis, and Vascular Biology. 45, 4, p. e136-e149Research output: Contribution to journal › Article › peer-review
2 Scopus citations -
Structure and cooperative formation of a FLI1 filament on contiguous GGAA DNA sites
Hou, C. & Tsodikov, O. V., Apr 11 2025, In: Nucleic Acids Research. 53, 6, gkaf205.Research output: Contribution to journal › Article › peer-review
Open Access -
The Position of Indole Methylation Controls the Structure, DNA Binding, and Cellular Functions of Mithramycin SA-Trp Analogues
Hou, C., Bhosale, S., Yasuda, K., Yetirajam, R., Leggas, M., Rohr, J. & Tsodikov, O. V., May 27 2025, In: ChemBioChem. 26, 10, e202401084.Research output: Contribution to journal › Article › peer-review
Open Access -
Transient interactions modulate the affinity of NF-κB transcription factors for DNA
Li, T., Shahabi, S., Biswas, T., Tsodikov, O. V., Pan, W., Huang, D. B., Wang, V. Y. F., Wang, Y. & Ghosh, G., Jun 4 2024, In: Proceedings of the National Academy of Sciences of the United States of America. 121, 23, e2405555121.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations