Grants and Contracts per year
Personal profile
Research Interests
Stable isotope resolved metabolomics.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
Doctor of Philosophy, Univ Of California - Davis
1987
Bachelor of Science, Univ Of Hawaii
1977
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Dive into the research topics where Richard Higashi is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Network
Recent external collaboration from the last 5 years on country level. Dive into details by clicking on the dots.
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Phase II Clinical Trial Evaluating Cabozantinib and Pembrolizumab in Second-Line Therapy for Metastatic Pancreatic Adenocarcinoma
Kim, J., Fan, W., Gao, M., Higashi, R., Rueckert, J. & Qasem, S.
12/15/21 → 6/7/23
Project: Research project
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Understanding Mechanisms and Consequences of T Cell Co-Receptor Regulated RNA Maturation
Lane, A., Fan, W. & Higashi, R.
4/5/21 → 3/31/24
Project: Research project
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Targeting Mitochondrial Redox Capacity to Overcome Cancer Subtype that Regrowth After Radiation
Chaiswing, L., Higashi, R., Luo, W., St Clair, W. & Weiss, H.
4/1/21 → 3/31/26
Project: Research project
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Altered Lipid Metabolism as a Novel Target for Colon Cancer Treatment
Evers, B. M., Higashi, R., Lee, E., Wang, C., Weiss, H., Zaytseva, Y., Gao, T., Goel, G. & Xiong, X.
8/1/17 → 7/31/23
Project: Research project
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University of Kentucky Center for Cancer Metabolism (Admin Core)
Zhou, B., Brainson, C., Cassis, L., D'Orazio, J., Evers, B. M., Fan, W., Fong, K. W., Hersh, L., Higashi, R., Jia, J., Lane, A., Liu, J., Liu, X., Liu, X., Marcinkowski, E., Moseley, H., Rellinger, E., Stromberg, A., Thorson, J., Van Eldik, L., Vanderford, N., Wang, C., Weiss, H., Wu, Y., Xu, R., St Clair, D., Arnold, S., Gentry, M., Hildebrandt, G., Wang, P. & Zhu, C.
National Institute of General Medical Sciences
3/1/17 → 12/31/26
Project: Research project
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A Micro-Scale Analytical Method for Determining Glycogen Turnover by NMR and FTMS
Scott, T. L., Zhu, J., Cassel, T. A., Vicente-Muñoz, S., Lin, P., Higashi, R. M., Lane, A. N. & Fan, T. W. M., Aug 2022, In: Metabolites. 12, 8, 760.Research output: Contribution to journal › Article › peer-review
Open Access -
Polarization and b-Glucan Reprogram Immunomodulatory Metabolism in Human Macrophages and Ex Vivo in Human Lung Cancer Tissues
Fan, T. W. M., Daneshmandi, S., Cassel, T. A., Uddin, M. B., Sledziona, J., Thompson, P. T., Lin, P., Higashi, R. M. & Lane, A. N., Nov 1 2022, In: Journal of Immunology. 209, 9, p. 1674-1690 17 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Ultrahigh resolution MS1/MS2-based reconstruction of metabolic networks in mammalian cells reveals changes for selenite and arsenite action
Fan, T. W. M., Sun, Q. & Higashi, R. M., Dec 2022, In: Journal of Biological Chemistry. 298, 12, 102586.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
6-phosphogluconate dehydrogenase (6pgd), a key checkpoint in reprogramming of regulatory t cells metabolism and function
Daneshmandi, S., Cassel, T., Higashi, R. M., Fan, T. W. M. & Seth, P., Oct 2021, In: eLife. 10, e67476.Research output: Contribution to journal › Article › peer-review
Open Access11 Scopus citations -
An Ion Chromatography-Ultrahigh-Resolution-MS1/Data-Independent High-Resolution MS2Method for Stable Isotope-Resolved Metabolomics Reconstruction of Central Metabolic Networks
Sun, Q., Fan, T. W. M., Lane, A. N. & Higashi, R. M., Feb 9 2021, In: Analytical Chemistry. 93, 5, p. 2749-2757 9 p.Research output: Contribution to journal › Article › peer-review
6 Scopus citations