Projects and Grants per year
Personal profile
Research Interests
Abl non-receptor tyrosine kinases, cancer invasion.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
Doctor of Philosophy, Indiana University
1992
Bachelor of Arts, Colorado College
1985
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Dive into the research topics where Rina Plattner is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Collaborations and top research areas from the last five years
Recent external collaboration from the last 5 years on country level. Dive into details by clicking on the dots.
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Targeting ABL1/2 And DDR1 Tyrosine Kinases for Treating NRAS-Mutant Melanoma
Plattner, R. (PI), Arays, R. (CoI), Liu, J. (CoI), Richards, D. (CoI) & Wang, C. (CoI)
6/1/25 → 6/1/29
Project: Research project
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Developing New Therapies for Metatsic Melanoma
Plattner, R. (PI), Goellner, E. (CoI), Liu, J. (CoI) & Richards, D. (CoI)
Markey Cancer Center Foundation
7/1/23 → 7/31/25
Project: Research project
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Combating Melanoma Resistance by Targeting ABL1/2
Plattner, R. (PI), Arays, R. (CoI), Gandhapudi, S. (CoI), Liu, J. (CoI), Richards, D. (CoI), Wang, C. (CoI), Yan, D. (CoI), Zhang, S. (CoI), Kolesar, J. (Former CoPI), COHEN, D. (Former CoI) & Wang, P. (Former CoI)
5/23/22 → 4/30/27
Project: Research project
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University of Kentucky Markey Cancer Center - Cancer Center Support Grant (Prime)
Evers, B. M. (PI), Adams, V. (CoI), Allison, D. (CoI), Anthony, L. (CoI), Arnold, S. (CoI), Bocklage, T. (CoI), Brainson, C. (CoI), Burris, J. (CoI), Burrows Franco, A. (CoI), Butterfield, D. A. (CoI), Chen, L. (CoI), Durbin, E. B. (CoI), Ellingson, S. (CoI), Gandhapudi, S. (CoI), Gao, T. (CoI), Hands, I. (CoI), Hao, Z. (CoI), Higashi, R. (CoI), Huang, B. (CoI), Hull, P. (CoI), Jeong, J. C. (CoI), Kavuluru, R. (CoI), Kuhs, K. (CoI), Lee, E. (CoI), Liu, J. (CoI), McGarry, R. (CoI), McLouth, L. (CoI), Moseley, H. (CoI), Mullett, T. (CoI), O'Connor, K. (CoI), Patel, R. (CoI), Plattner, R. (CoI), Rogers, J. (CoI), Shelton, B. (CoI), St Clair, D. (CoI), Sturgill, J. (CoI), Vanderford, N. (CoI), Villano, PhD, J. (CoI), Wang, C. (CoI), Wei, S. (CoI), Weiss, H. (CoI), Williams, L. (CoI), Yan, D. (CoI), Zhang, S. (CoI), Zhou, B. (CoI), COHEN, D. (Former CoI), Kolesar, J. (Former CoI), Kunos, C. (Former CoI), Stanley, S. (Former CoI), Stapleton, J. (Former CoI) & Woodward, J. (Former CoI)
7/8/13 → 6/30/28
Project: Research project
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University of Kentucky Markey Cancer Center - Cancer Center Support Grant (Clinical Protocol and Data Management (CPMD))
Evers, B. M. (PI), Adams, V. (CoI), Allison, D. (CoI), Anthony, L. (CoI), Arnold, S. (CoI), Bocklage, T. (CoI), Burris, J. (CoI), Butterfield, D. A. (CoI), Chen, L. (CoI), COHEN, D. (CoI), Durbin, E. B. (CoI), Ellingson, S. (CoI), Gao, T. (CoI), Hands, I. (CoI), Higashi, R. (CoI), Huang, B. (CoI), Hull, P. (CoI), Jeong, J. C. (CoI), Kavuluru, R. (CoI), Kuhs, K. (CoI), Kunos, C. (CoI), Lee, E. (CoI), Liu, J. (CoI), McGarry, R. (CoI), Moseley, H. (CoI), Mullett, T. (CoI), O'Connor, K. (CoI), Patel, R. (CoI), Plattner, R. (CoI), Rogers, J. (CoI), Shelton, B. (CoI), St Clair, D. (CoI), Stanley, S. (CoI), Stapleton, J. (CoI), Sturgill, J. (CoI), Vanderford, N. (CoI), Villano, PhD, J. (CoI), Wang, C. (CoI), Wei, S. (CoI), Weiss, H. (CoI), Williams, L. (CoI), Woodward, J. (CoI), Yan, D. (CoI), Zhang, S. (CoI), Zhou, B. (CoI) & Kolesar, J. (Former CoI)
7/8/13 → 6/30/28
Project: Research project
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ABL1/2 and DDR1 Drive MEKi Resistance in NRAS-Mutant Melanomas by Stabilizing RAF/MYC/ETS1 and Promoting RAF Homodimerization
Lyon, A., Tripathi, R., Meeks, C., He, D., Wu, Y., Liu, J., Wang, C., Chen, J., Zhu, H., Mukherjee, S., Ganguly, S. & Plattner, R., Feb 2023, In: Cancers. 15, 3, 954.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Inhibition of ABL1 by tyrosine kinase inhibitors leads to a downregulation of MLH1 by Hsp70-mediated lysosomal protein degradation
Daniels, H. G., Knicely, B. G., Miller, A. K., Thompson, A., Plattner, R. & Goellner, E. M., Oct 20 2022, In: Frontiers in Genetics. 13, 940073.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Keap1 is required for artesunate anticancer activity in non-small-cell lung cancer
Hill, K. S., McDowell, A., McCorkle, J. R., Schuler, E., Ellingson, S. R., Plattner, R. & Kolesar, J. M., Apr 2 2021, In: Cancers. 13, 8, 1885.Research output: Contribution to journal › Article › peer-review
Open Access13 Scopus citations -
Combating acquired resistance to MAPK inhibitors in melanoma by targeting Abl1/2-mediated reactivation of MEK/ERK/MYC signaling
Tripathi, R., Liu, Z., Jain, A., Lyon, A., Meeks, C., Richards, D., Liu, J., He, D., Wang, C., Nespi, M., Rymar, A., Wang, P., Wilson, M. & Plattner, R., Dec 1 2020, In: Nature Communications. 11, 1, 5463.Research output: Contribution to journal › Article › peer-review
Open Access31 Scopus citations -
Potential protein markers for breast cancer recurrence: a retrospective cohort study
He, C., Plattner, R., Rangnekar, V., Zhou, B., Liu, C., Stewart, R. L., Huang, B., Wang, C. & Tucker, T. C., Jan 1 2019, In: Cancer Causes and Control. 30, 1, p. 41-51 11 p.Research output: Contribution to journal › Article › peer-review
Open Access5 Scopus citations