Grants and Contracts per year
Personal profile
Research Interests
Abl non-receptor tyrosine kinases, cancer invasion.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
Doctor of Philosophy, Indiana University
1992
Bachelor of Arts, Colorado College
1985
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Network
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Combating Melanoma Resistance by Targeting ABL1/2
Plattner, R., COHEN, D., Liu, J., Richards, D., Wang, C., Yan, D., Zhang, S., Kolesar, J. & Wang, P.
5/23/22 → 4/30/27
Project: Research project
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Targeting Abl Kinases in BRAF-Driven Melanomas
Plattner, R., Richards, D., Weiss, H., Wang, P. & Zhu, H.
8/13/18 → 7/31/23
Project: Research project
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University of Kentucky Markey Cancer Center - Cancer Center Support Grant
Evers, B. M., Adams, V., Allison, D., Anthony, L., Arnold, S., Bocklage, T., Burris, J., Butterfield, D. A., Chen, L., Dignan, M., Durbin, E., Ellingson, S., Gandhapudi, S., Gao, T., Higashi, R., Huang, B., Hull, P., Jeong, J. C., Kavuluru, R., Kolesar, J., Kuhs, K., Kunos, C., Lee, E., Liu, J., McGarry, R., Moseley, H., O'Connor, K., Patel, R., Plattner, R., Rangnekar, V., Rogers, J., Shelton, B., St Clair, D., Stanley, S., Stapleton, J., Sturgill, J., Vanderford, N., Wang, C., Wei, S., Weiss, H., Williams, L., Yan, D., Zhang, S., Zhou, B., COHEN, D., D'Orazio, J., Feddock, J., Gosky, D., Hao, Z., He, C., Hodges, K., Jennings, C., Liu, J., Purdom, M., Saeed, H., Shi, Q., Stewart, R., Studts, J., Thorson, J., Tucker, T., Vanderpool, R., Woodward, J., Wu, J. & Zhu, H.
7/8/13 → 6/30/23
Project: Research project
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FY21 Artesunate as Treatment for Childhood Acute Myeloid Leukemia
Kolesar, J., Badgett, J., Hill, K., Ji, H., Plattner, R., Wu, J. & Yuan, L.
KY Cabinet for Health and Family Services
7/1/20 → 6/30/21
Project: Research project
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FY22 Artesunate as Treatment for Childhood Acute Myeloid Leukemia
Kolesar, J., Badgett, J., Hill, K., Ji, H., Plattner, R., Yuan, L. & Wu, J.
KY Cabinet for Health and Family Services
7/1/20 → 6/30/22
Project: Research project
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ABL1/2 and DDR1 Drive MEKi Resistance in NRAS-Mutant Melanomas by Stabilizing RAF/MYC/ETS1 and Promoting RAF Homodimerization
Lyon, A., Tripathi, R., Meeks, C., He, D., Wu, Y., Liu, J., Wang, C., Chen, J., Zhu, H., Mukherjee, S., Ganguly, S. & Plattner, R., Feb 2023, In: Cancers. 15, 3, 954.Research output: Contribution to journal › Article › peer-review
Open Access -
Inhibition of ABL1 by tyrosine kinase inhibitors leads to a downregulation of MLH1 by Hsp70-mediated lysosomal protein degradation
Daniels, H. G., Knicely, B. G., Miller, A. K., Thompson, A., Plattner, R. & Goellner, E. M., Oct 20 2022, In: Frontiers in Genetics. 13, 940073.Research output: Contribution to journal › Article › peer-review
Open Access -
Keap1 is required for artesunate anticancer activity in non-small-cell lung cancer
Hill, K. S., McDowell, A., McCorkle, J. R., Schuler, E., Ellingson, S. R., Plattner, R. & Kolesar, J. M., Apr 2 2021, In: Cancers. 13, 8, 1885.Research output: Contribution to journal › Article › peer-review
Open Access3 Scopus citations -
Combating acquired resistance to MAPK inhibitors in melanoma by targeting Abl1/2-mediated reactivation of MEK/ERK/MYC signaling
Tripathi, R., Liu, Z., Jain, A., Lyon, A., Meeks, C., Richards, D., Liu, J., He, D., Wang, C., Nespi, M., Rymar, A., Wang, P., Wilson, M. & Plattner, R., Dec 1 2020, In: Nature Communications. 11, 1, 5463.Research output: Contribution to journal › Article › peer-review
Open Access18 Scopus citations -
Potential protein markers for breast cancer recurrence: a retrospective cohort study
He, C., Plattner, R., Rangnekar, V., Zhou, B., Liu, C., Stewart, R. L., Huang, B., Wang, C. & Tucker, T. C., Jan 1 2019, In: Cancer Causes and Control. 30, 1, p. 41-51 11 p.Research output: Contribution to journal › Article › peer-review
3 Scopus citations