Grants and Contracts per year
Personal profile
Research Interests
Dr. Gedaly is a Hepatobiliary and Transplant surgeon and Chief of the Abdominal Transplant section. He has extensive clinical expertise in the management of patients with hepatocellular carcinoma and a strong interest in basic science and clinical science research in the areas of hepatocellular carcinoma and other liver diseases as well as hepatocellular carcinoma markers and their impact on patient outcomes.
Dr. Gedaly has published several articles in the fields of transplantation and hepatobiliary surgery, including, “Predictors of relapse to alcohol and illicit drugs after liver transplantation for alcoholic liver disease”. His work has reported the impact of obesity, diabetes, smoking and cancer on resource utilization in patients undergoing liver resection from a multicenter analysis of 1029 hepatectomies. In addition, he has reported the association of alpha-fetaprotein and tumor size with microvascular invasion in patients undergoing transplantation with hepatocellular carcinoma.
Recently, Dr. Gedaly obtained promising results studying the function and mechanism of multi-kinase inhibitor sorafenib and dual PI3K and mTOR inhibitor PI-103 on inhibition of HCC in vitro and in a nude mice model.
In recent years, his laboratory has studied the role of combination therapy while targeting significant pathways in HCC treatment. Most recently, his laboratory has studied the role of liver cancer stem cells in HCC treatment.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
Post Doctoral Fellow, Other Institution
1999
Residency, Other Institution
1995
Doctor of Medicine, Other Institution
1990
Fingerprint
- 1 Similar Profiles
Network
-
Impact of Envarsus XR on Kidney Biopsy Subclinical Rejection and Blood Immunologic Profile
Gedaly, R., Marti, F., Rendulic, T. & Berger, J.
Veloxis Pharmaceuticals Incorporated
11/6/17 → 2/7/24
Project: Research project
-
Tolerance Induction Using Autologous Regulatory T Cell Infusion and Zortress (Everolimus) in Renal Transplant Recipients: a pilot study
2/28/17 → 7/31/23
Project: Research project
-
AZD8055 on Regulatory T cell Manufacturing for Clinical Use in Transplantation
AstraZeneca Pharmaceuticals AB
2/6/21 → 1/31/23
Project: Research project
-
Anti-neoplastic sulfonamides alter the metabolic homeostasis and disrupt the suppressor activity of regulatory T cells
Gedaly, R., Cornea, V., Turcios, L., Edmisson, J. S., Harris, D. D., Watt, D. S., Chapelin, F., Khurana, A., Mei, X., Liu, C., Taylor, I., Gonzalez-Valdivieso, J., Mitchel, H., Ruffing, A., Chishti, A., Orozco, G., Zwischenberger, J., Evers, B. M. & Marti, F., Dec 2022, In: Scientific Reports. 12, 1, 19112.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
Cell sorting microbeads as novel contrast agent for magnetic resonance imaging
Khurana, A., Marti, F., Powell, D. K., Brandon, J. A., Dugan, A., Gedaly, R. & Chapelin, F., Dec 2022, In: Scientific Reports. 12, 1, 17640.Research output: Contribution to journal › Article › peer-review
Open Access -
Outcomes in Elderly Patients Undergoing Liver Transplantation Compared with Liver-Directed Ablative Therapy in Early-Stage Hepatocellular Carcinoma
Shah, M. B., Villagomez Rubio, D. A., Orozco, G., Desai, S., Ancheta, A., Gupta, M., Mei, X., Evers, B. M., Gedaly, R. & Cannon, R. M., May 1 2022, In: Journal of the American College of Surgeons. 234, 5, p. 892-899 8 p.Research output: Contribution to journal › Article › peer-review
1 Scopus citations -
Predictors of Liver Failure in Non-Cirrhotic Patients Undergoing Hepatectomy
Orozco, G., Gupta, M., Villagomez, D., Shah, M., Marti, F., Mei, X., Ancheta, A., Desai, S., Salama, F., Benrajab, K., Davenport, D. & Gedaly, R., Dec 2022, In: World Journal of Surgery. 46, 12, p. 3081-3089 9 p.Research output: Contribution to journal › Article › peer-review
1 Scopus citations -
Prognostic Value of Fluorine-19 MRI Oximetry Monitoring in cancer
Chapelin, F., Gedaly, R., Sweeney, Z. & Gossett, L. J., Apr 2022, In: Molecular Imaging and Biology. 24, 2, p. 208-219 12 p.Research output: Contribution to journal › Review article › peer-review
2 Scopus citations