Dr. Gedaly is a Hepatobiliary and Transplant surgeon and Chief of the Abdominal Transplant section. He has extensive clinical expertise in the management of patients with hepatocellular carcinoma and a strong interest in basic science and clinical science research in the areas of hepatocellular carcinoma and other liver diseases as well as hepatocellular carcinoma markers and their impact on patient outcomes.

Dr. Gedaly has published several articles in the fields of transplantation and hepatobiliary surgery, including, “Predictors of relapse to alcohol and illicit drugs after liver transplantation for alcoholic liver disease”. His work has reported the impact of obesity, diabetes, smoking and cancer on resource utilization in patients undergoing liver resection from a multicenter analysis of 1029 hepatectomies. In addition, he has reported the association of alpha-fetaprotein and tumor size with microvascular invasion in patients undergoing transplantation with hepatocellular carcinoma.

Recently, Dr. Gedaly obtained promising results studying the function and mechanism of multi-kinase inhibitor sorafenib and dual PI3K and mTOR inhibitor PI-103 on inhibition of HCC in vitro and in a nude mice model.

In recent years, his laboratory has studied the role of combination therapy while targeting significant pathways in HCC treatment. Most recently, his laboratory has studied the role of liver cancer stem cells in HCC treatment.