Projects and Grants per year
Personal profile
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
Post Doctoral Fellow, Boston Children's Hospital
2016
Residency, Indiana University
2012
Doctor of Medicine, Wright State University
2007
Bachelor of Science, University Of Cincinnati
2002
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Collaborations and top research areas from the last five years
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Elucidating Molecular Mechanisms Linking Fructose to Cholesterol Metabolism
Helsley, R., Graf, G., Lane, A. & Softic, S.
National Institute Diabetes & Digestive & Kidney
1/1/22 → 12/31/26
Project: Research project
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Mechanisms Regulating the Atherogenic Activities of Serum Amyloid A
Shridas, P., Softic, S., Tannock, L. & Webb, N.
National Heart Lung and Blood Institute
7/5/20 → 6/30/25
Project: Research project
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Elucidating Molecular Mechanisms Linking Fructose to Cholesterol Metabolism
Helsley, R., Graf, G., Lane, A. & Softic, S.
National Institute Diabetes & Digestive & Kidney
1/1/22 → 12/31/23
Project: Research project
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Targeting Fructose Metabolism for the Treatment of NAFLD and T2D
Alnylam Pharmaceuticals Incorporated
4/15/21 → 8/30/23
Project: Research project
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A luminescence-based protocol for assessing fructose metabolism via quantification of ketohexokinase enzymatic activity in mouse or human hepatocytes
Park, S-H., Helsley, R. N., Noetzli, L., Tu, H-C., Wallenius, K., O'Mahony, G., Boucher, J., Liu, J. & Softic, S., Sep 17 2021, In: STAR Protocols. 2, 3, p. 100731Research output: Contribution to journal › Article › peer-review
4 Scopus citations -
KHK PROMOTES HEPATIC LIPID DEPOSITION BY REPRESSING CPT1a-MEDIATED FATTY ACID OXIDATION
Helsley, R., Park, S-H., Vekaria, H. J., Sullivan, P. G., Meyer, J. G., Schilling, B., Kahn, C. R. & Softic, S., Oct 2021, In: Hepatology. 74, p. 1074A-1074AResearch output: Contribution to journal › Meeting Abstract › peer-review
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Non-hematopoietic IL-4R alpha expression contributes to fructose-driven obesity and metabolic sequelae
Damen, M. S. M. A., Stankiewicz, T. E., Park, S-H., Helsley, R. N., Chan, C. C., Moreno-Fernandez, M. E., Doll, J. R., Szabo, S., Herbert, DB. R., Softic, S. & Divanovic, S., Nov 2021, In: International Journal of Obesity. 45, 11, p. 2377-2387Research output: Contribution to journal › Article › peer-review
4 Scopus citations -
Fructose metabolism by the guts cuts liver fat
Helsley, R. N. & Softic, S., May 2020, In: Journal of Molecular Medicine. 98, 5, p. 733-734Research output: Contribution to journal › Editorial
2 Scopus citations -
Tissue-Specific Fructose Metabolism in Obesity and Diabetes
Helsley, R. N., Moreau, F., Gupta, M. K., Radulescu, A., DeBosch, B. & Softic, S., Oct 15 2020, In: Current Diabetes Reports. 20, 11Research output: Contribution to journal › Review article › peer-review
40 Scopus citations