Projects and Grants per year
Personal profile
Research Interests
The Gordon lab studies metabolism and atherosclerotic cardiovascular disease in two primary lines of investigation:
Mechanisms regulating dietary fat absorption by the intestine.
- Genes that control chylomicron secretion.
- The influence of fat absorption on body weight, metabolism, and atherosclerosis.
Inflammatory protease activity in the artery wall and suppression by lipoproteins.
- Natural mechanisms of inflammatory regulation involving lipoproteins.
- Development of lipoprotein-targeting protease inhibitors.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
Doctor of Philosophy, University Of Cincinnati
2012
Bachelor of Science, State University Of New York
2008
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Collaborations and top research areas from the last five years
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Functional Interactions Between Lipoproteins and Protease Inhibitors in Atherosclerosis
Gordon, S. (PI) & Daugherty, A. (CoI)
National Heart Lung and Blood Institute
7/1/24 → 4/30/28
Project: Research project
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Identification of Carnitine Palmitoyltransferase 1a (CPT1a) as a Novel Regulator of Lipoprotein Metabolism
Helsley, R. (PI), Daugherty, A. (CoI), Gordon, S. (CoI) & Graf, G. (CoI)
4/1/23 → 3/31/26
Project: Research project
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APOE Allelic Switching to Delay or Prevent Alzheimer's Disease
Johnson, L. (PI), Gordon, S. (CoI), Morganti, J. (CoI) & Sun, R. (Former CoI)
10/1/22 → 9/30/25
Project: Research project
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The Role of DENND5B in Dietary Lipid Absorption
Gordon, S. (PI) & Graf, G. (CoI)
National Institute Diabetes & Digestive & Kidney
7/15/22 → 5/31/27
Project: Research project
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Identification of Carnitine Palmitoyltransferase 1a (CPT1a) as a Novel Regulator of Lipoprotein Metabolism
Helsley, R. (PI), Daugherty, A. (CoI), Gordon, S. (CoI) & Graf, G. (CoI)
4/1/23 → 3/31/24
Project: Research project
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Asthmatic patients with high serum amyloid A have proinflammatory HDL: Implications for augmented systemic and airway inflammation
Yao, X., Kaler, M., Qu, X., Kalidhindi, R. S. R., Sviridov, D., Dasseux, A., Barr, E., Keeran, K., Jeffries, K. R., Yu, Z. X., Gao, M., Gordon, S., Barochia, A. V., Mills, J., Shahid, S., Weir, N. A., Kalchiem-Dekel, O., Theard, P., Playford, M. P. & Stylianou, M. & 3 others, , Apr 2024, In: Journal of Allergy and Clinical Immunology. 153, 4, p. 1010-1024.e14Research output: Contribution to journal › Article › peer-review
2 Scopus citations -
Enhancement of high-density lipoprotein-associated protease inhibitor activity prevents atherosclerosis progression
Mobilia, M., Karakashian, A., Neupane, K. R., Hage, O., Whitus, C., Carter, A., Voy, C., Johnson, L. A., Graf, G. A. & Gordon, S. M., Sep 2024, In: Atherosclerosis. 396, 118544.Research output: Contribution to journal › Article › peer-review
Open Access -
The nonvesicular sterol transporter Aster-C plays a minor role in whole body cholesterol balance
Banerjee, R., Hohe, R. C., Cao, S., Jung, B. M., Horak, A. J., Ramachandiran, I., Massey, W. J., Varadharajan, V., Zajczenko, N. I., Burrows, A. C., Dutta, S., Goudarzi, M., Mahen, K., Carter, A., Helsley, R., Gordon, S. M., Morton, R. E., Strauch, C., Willard, B. & Gogonea, C. B. & 4 others, , 2024, In: Frontiers in Physiology. 15, 1371096.Research output: Contribution to journal › Article › peer-review
Open Access -
Cell-free, high-density lipoprotein-specific phospholipid efflux assay predicts incident cardiovascular disease
Sato, M., Neufeld, E. B., Playford, M. P., Lei, Y., Sorokin, A. V., Aponte, A. M., Freeman, L. A., Gordon, S. M., Dey, A. K., Jeiran, K., Hamasaki, M., Sampson, M. L., Shamburek, R. D., Tang, J., Chen, M. Y., Kotani, K., Anderson, J. L. C., Dullaart, R. P. F., Mehta, N. N. & Tietge, U. J. F. & 1 others, , Sep 15 2023, In: Journal of Clinical Investigation. 133, 18, e165370.Research output: Contribution to journal › Article › peer-review
Open Access7 Scopus citations -
Prenatal Morphine Exposure Increases Cardiovascular Disease Risk and Programs Neurogenic Hypertension in the Adult Offspring
Ahmed, N., Kassis, A., Malone, J., Yang, J., Zamzami, E., Lin, A. H., Gordon, S. M., Gong, M. C., Bardo, M., Dalmasso, C. & Loria, A. S., Jun 1 2023, In: Hypertension. 80, 6, p. 1283-1296 14 p.Research output: Contribution to journal › Article › peer-review
6 Scopus citations