Projects and Grants per year
Personal profile
Research Interests
The Gordon lab studies metabolism and atherosclerotic cardiovascular disease in two primary lines of investigation:
Mechanisms regulating dietary fat absorption by the intestine.
- Genes that control chylomicron secretion.
- The influence of fat absorption on body weight, metabolism, and atherosclerosis.
Inflammatory protease activity in the artery wall and suppression by lipoproteins.
- Natural mechanisms of inflammatory regulation involving lipoproteins.
- Development of lipoprotein-targeting protease inhibitors.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
Doctor of Philosophy, University Of Cincinnati
2012
Bachelor of Science, State University Of New York
2008
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Collaborations and top research areas from the last five years
Recent external collaboration from the last 5 years on country level. Dive into details by clicking on the dots.
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Investigating the Role of HDL-Associated Serum Amyloid A in Sepsis-induced Acute Lung Injury and Mortality
Shridas, P. (PI), Absher, K. (CoI), Brainson, C. (CoI), Gordon, S. (CoI), Kryscio, R. (CoI), Starr, M. (CoI) & Waters, C. (CoI)
National Heart Lung and Blood Institute
1/1/25 → 11/30/28
Project: Research project
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Fellowship for Clairity Voy: The Impact of Proteolytic Modification of Lipoprotein Metabolism and Atherosclerosis
Gordon, S. (PI)
1/1/25 → 12/31/26
Project: Research project
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Functional Interactions Between Lipoproteins and Protease Inhibitors in Atherosclerosis
Gordon, S. (PI) & Daugherty, A. (CoI)
National Heart Lung and Blood Institute
7/1/24 → 4/30/28
Project: Research project
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Fellowship for Olivia Hage: The role of Dennd5b in Triglyceride-Rich Lipoprotein Secretion from the Liver and Intestine
Gordon, S. (PI) & Hage, O. (CoI)
1/1/24 → 12/31/25
Project: Research project
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APOE Allele Switching as a Therapeutic Approach for Alzheimer's Disease
Johnson, L. (PI), Gordon, S. (CoI), Morganti, J. (CoPI) & Sun, R. (Former CoI)
12/1/22 → 11/30/27
Project: Research project
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HDL-associated vitamin D binding protein levels are inversely associated with necrotic plaque burden in psoriasis
Playford, M. P., Li, H., Dey, A. K., Florida, E. M., Teague, H. L., Gordon, S. M. & Mehta, N. N., Mar 2025, In: Atherosclerosis Plus. 59, p. 32-38 7 p.Research output: Contribution to journal › Article › peer-review
Open Access -
APOA2 increases cholesterol efflux capacity to plasma HDL by displacing the C-terminus of resident APOA1
Sarkar, S., Morris, J., You, Y., Sexmith, H., Street, S. E., Thibert, S. M., Attah, I. K., Hutchinson Bunch, C. M., Novikova, I. V., Evans, J. E., Shah, A. S., Gordon, S. M., Segrest, J. P., Bornfeldt, K. E., Vaisar, T., Heinecke, J. W., Davidson, W. S. & Melchior, J. T., Dec 2024, In: Journal of Lipid Research. 65, 12, 100686.Research output: Contribution to journal › Article › peer-review
1 Scopus citations -
Asthmatic patients with high serum amyloid A have proinflammatory HDL: Implications for augmented systemic and airway inflammation
Yao, X., Kaler, M., Qu, X., Kalidhindi, R. S. R., Sviridov, D., Dasseux, A., Barr, E., Keeran, K., Jeffries, K. R., Yu, Z. X., Gao, M., Gordon, S., Barochia, A. V., Mills, J., Shahid, S., Weir, N. A., Kalchiem-Dekel, O., Theard, P., Playford, M. P. & Stylianou, M. & 3 others, , Apr 2024, In: Journal of Allergy and Clinical Immunology. 153, 4, p. 1010-1024.e14Research output: Contribution to journal › Article › peer-review
4 Scopus citations -
Enhancement of high-density lipoprotein-associated protease inhibitor activity prevents atherosclerosis progression
Mobilia, M., Karakashian, A., Neupane, K. R., Hage, O., Whitus, C., Carter, A., Voy, C., Johnson, L. A., Graf, G. A. & Gordon, S. M., Sep 2024, In: Atherosclerosis. 396, 118544.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
The nonvesicular sterol transporter Aster-C plays a minor role in whole body cholesterol balance
Banerjee, R., Hohe, R. C., Cao, S., Jung, B. M., Horak, A. J., Ramachandiran, I., Massey, W. J., Varadharajan, V., Zajczenko, N. I., Burrows, A. C., Dutta, S., Goudarzi, M., Mahen, K., Carter, A., Helsley, R. N., Gordon, S. M., Morton, R. E., Strauch, C., Willard, B. & Gogonea, C. B. & 4 others, , 2024, In: Frontiers in Physiology. 15, 1371096.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations