Projects and Grants per year
Personal profile
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
Doctor of Philosophy, University Of Groningen
2003
Master of Science, University Of Plovdiv
1999
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Collaborations and top research areas from the last five years
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Function of Ceramide in Extracellular Vesicle-Mediated Neurodegenerative Disease
Bieberich, E. (PI), McClintock, T. (CoI), Spassieva, S. (CoI) & Rabchevsky, A. (Former CoI)
9/1/22 → 8/31/25
Project: Research project
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IPA: TBI-induced Exosome Release Accelerates Alzheimer#s Disease Pathology
Spassieva, S. (PI) & Bieberich, E. (CoI)
12/1/22 → 11/30/23
Project: Research project
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Novel Experimental Models to Study the Effect of Extracellular Vesicles on Neurons
Bieberich, E. (PI), McClintock, T. (CoI), Rabchevsky, A. (CoI) & Spassieva, S. (CoI)
8/17/22 → 7/31/24
Project: Research project
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L-Serine Supplementation for Prevention of Taxane-Induced Peripheral Neuropathy
Spassieva, S. (PI) & O'Connor, K. (CoI)
12/15/19 → 12/31/20
Project: Research project
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Regulation of Cilia by Ceramide
Bieberich, E. (PI), Spassieva, S. (CoI) & Wang, G. (Former CoI)
National Institute of Neurological Disorders & Stroke
9/30/16 → 6/30/21
Project: Research project
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Abnormal Regulation of Mitochondrial Sphingolipids during Aging and Alzheimer’s Disease
Crivelli, S. M., Quadri, Z., Elsherbini, A., Vekaria, H. J., Sullivan, P. G., Zhi, W., Martinez-Martinez, P., Spassieva, S. D. & Bieberich, E., 2024, In: ASN Neuro. 16, 1, 2404367.Research output: Contribution to journal › Article › peer-review
Open Access -
Ceramide-mediated orchestration of oxidative stress response through filopodia-derived small extracellular vesicles
Quadri, Z., Elsherbini, A., Crivelli, S. M., El-Amouri, S. S., Tripathi, P., Zhu, Z., Ren, X., Zhang, L., Spassieva, S. D., Nikolova-Karakashian, M. & Bieberich, E., Jul 2024, In: Journal of Extracellular Vesicles. 13, 7, e12477.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
The S1P receptor 1 antagonist Ponesimod reduces TLR4-induced neuroinflammation and increases Aβ clearance in 5XFAD mice
Zhu, Z., Zhang, L., Elsherbini, A., Crivelli, S. M., Tripathi, P., Harper, C., Quadri, Z., Spassieva, S. D. & Bieberich, E., Aug 2023, In: EBioMedicine. 94, 104713.Research output: Contribution to journal › Article › peer-review
Open Access11 Scopus citations -
Function of ceramide transfer protein for biogenesis and sphingolipid composition of extracellular vesicles
Crivelli, S. M., Giovagnoni, C., Zhu, Z., Tripathi, P., Elsherbini, A., Quadri, Z., Pu, J., Zhang, L., Ferko, B., Berkes, D., Spassieva, S. D., Martinez-Martinez, P. & Bieberich, E., Jun 2022, In: Journal of Extracellular Vesicles. 11, 6, e12233.Research output: Contribution to journal › Article › peer-review
Open Access41 Scopus citations -
Neutral Sphingomyelinase 2 Mediates Oxidative Stress Effects on Astrocyte Senescence and Synaptic Plasticity Transcripts
Zhu, Z., Quadri, Z., Crivelli, S. M., Elsherbini, A., Zhang, L., Tripathi, P., Qin, H., Roush, E., Spassieva, S. D., Nikolova-Karakashian, M., McClintock, T. S. & Bieberich, E., May 2022, In: Molecular Neurobiology. 59, 5, p. 3233-3253 21 p.Research output: Contribution to journal › Article › peer-review
Open Access9 Scopus citations