Susanne Arnold

Susanne Arnold, MD

  • 800 Rose Street

    40536 Lexington

    United States

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19982022

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  • 2022

    A Large-Scale Genome-Wide Gene-Gene Interaction Study of Lung Cancer Susceptibility in Europeans With a Trans-Ethnic Validation in Asians

    Zhang, R., Shen, S., Wei, Y., Zhu, Y., Li, Y., Chen, J., Guan, J., Pan, Z., Wang, Y., Zhu, M., Xie, J., Xiao, X., Zhu, D., Li, Y., Albanes, D., Landi, M. T., Caporaso, N. E., Lam, S., Tardon, A., Chen, C., & 31 othersBojesen, S. E., Johansson, M., Risch, A., Bickeböller, H., Wichmann, H. E., Rennert, G., Arnold, S., Brennan, P., McKay, J. D., Field, J. K., Shete, S. S., Le Marchand, L., Liu, G., Andrew, A. S., Kiemeney, L. A., Zienolddiny-Narui, S., Behndig, A., Johansson, M., Cox, A., Lazarus, P., Schabath, M. B., Aldrich, M. C., Dai, J., Ma, H., Zhao, Y., Hu, Z., Hung, R. J., Amos, C. I., Shen, H., Chen, F. & Christiani, D. C., Aug 2022, In: Journal of Thoracic Oncology. 17, 8, p. 974-990 17 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    4 Scopus citations
  • Cancer diagnosis is associated with a lower burden of dementia and less Alzheimer's-Type neuropathology

    Karanth, S. D., Katsumata, Y., Nelson, P. T., Fardo, D. W., McDowell, J. K., Schmitt, F. A., Kryscio, R. J., Browning, S. R., Braithwaite, D., Arnold, S. M. & Abner, E. L., Jul 1 2022, In: Brain. 145, 7, p. 2518-2527 10 p.

    Research output: Contribution to journalArticlepeer-review

    2 Scopus citations
  • Cross-ancestry genome-wide meta-analysis of 61,047 cases and 947,237 controls identifies new susceptibility loci contributing to lung cancer

    Byun, J., Han, Y., Li, Y., Xia, J., Long, E., Choi, J., Xiao, X., Zhu, M., Zhou, W., Sun, R., Bossé, Y., Song, Z., Schwartz, A., Lusk, C., Rafnar, T., Stefansson, K., Zhang, T., Zhao, W., Pettit, R. W., Liu, Y., & 65 othersLi, X., Zhou, H., Walsh, K. M., Gorlov, I., Gorlova, O., Zhu, D., Rosenberg, S. M., Pinney, S., Bailey-Wilson, J. E., Mandal, D., de Andrade, M., Gaba, C., Willey, J. C., You, M., Anderson, M., Wiencke, J. K., Albanes, D., Lam, S., Tardon, A., Chen, C., Goodman, G., Bojeson, S., Brenner, H., Landi, M. T., Chanock, S. J., Johansson, M., Muley, T., Risch, A., Wichmann, H. E., Bickeböller, H., Christiani, D. C., Rennert, G., Arnold, S., Field, J. K., Shete, S., Le Marchand, L., Melander, O., Brunnstrom, H., Liu, G., Andrew, A. S., Kiemeney, L. A., Shen, H., Zienolddiny, S., Grankvist, K., Johansson, M., Caporaso, N., Cox, A., Hong, Y. C., Yuan, J. M., Lazarus, P., Schabath, M. B., Aldrich, M. C., Patel, A., Lan, Q., Rothman, N., Taylor, F., Kachuri, L., Witte, J. S., Sakoda, L. C., Spitz, M., Brennan, P., Lin, X., McKay, J., Hung, R. J. & Amos, C. I., Aug 2022, In: Nature Genetics. 54, 8, p. 1167-1177 11 p.

    Research output: Contribution to journalArticlepeer-review

    2 Scopus citations
  • Durvalumab plus tremelimumab alone or in combination with low-dose or hypofractionated radiotherapy in metastatic non-small-cell lung cancer refractory to previous PD(L)-1 therapy: an open-label, multicentre, randomised, phase 2 trial

    Schoenfeld, J. D., Giobbie-Hurder, A., Ranasinghe, S., Kao, K. Z., Lako, A., Tsuji, J., Liu, Y., Brennick, R. C., Gentzler, R. D., Lee, C., Hubbard, J., Arnold, S. M., Abbruzzese, J. L., Jabbour, S. K., Uboha, N. V., Stephans, K. L., Johnson, J. M., Park, H., Villaruz, L. C., Sharon, E., & 17 othersStreicher, H., Ahmed, M. M., Lyon, H., Cibuskis, C., Lennon, N., Jhaveri, A., Yang, L., Altreuter, J., Gunasti, L., Weirather, J. L., Mak, R. H., Awad, M. M., Rodig, S. J., Chen, H. X., Wu, C. J., Monjazeb, A. M. & Hodi, F. S., Feb 2022, In: The Lancet Oncology. 23, 2, p. 279-291 13 p.

    Research output: Contribution to journalArticlepeer-review

    30 Scopus citations
  • Exceptional Survival Among Kentucky Stage IV Non-small Cell Lung Cancer Patients: Appalachian Versus Non-Appalachian Populations

    Pravosud, V., Vanderford, N. L., Huang, B., Tucker, T. C. & Arnold, S. M., Jan 1 2022, In: Journal of Rural Health. 38, 1, p. 14-27 14 p.

    Research output: Contribution to journalArticlepeer-review

  • Factors Predicting Participation in the Prospective Genomic Sequencing Study, Total Cancer Care (TCC), in Kentucky

    Riggs, M. J., Huang, B., Chen, Q., Bocklage, T., Schuh, M. R., Poi, M., Villano, J. L., Cavnar, M. J., Arnold, S. M., Miller, R. W., Ueland, F. R. & Kolesar, J. M., Jan 1 2022, In: Journal of Rural Health. 38, 1, p. 5-13 9 p.

    Research output: Contribution to journalArticlepeer-review

    1 Scopus citations
  • Gene–gene interaction of AhRwith and within the Wntcascade affects susceptibility to lung cancer

    Dec 2022, In: European Journal of Medical Research. 27, 1, 14.

    Research output: Contribution to journalArticlepeer-review

    Open Access
  • Genome-wide interaction analysis identified low-frequency variants with sex disparity in lung cancer risk

    Aug 23 2022, In: Human Molecular Genetics. 31, 16, p. 2831-2843 13 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
  • hPG80 (Circulating Progastrin), a Novel Blood-Based Biomarker for Detection of Poorly Differentiated Neuroendocrine Carcinoma and Well Differentiated Neuroendocrine Tumors

    Chauhan, A., Prieur, A., Kolesar, J., Arnold, S., Payen, L., Mahi, Y., Vire, B., Sands, M., Evers, B. M., Joubert, D. & Anthony, L., Feb 1 2022, In: Cancers. 14, 4, 863.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    2 Scopus citations
  • I am hiQ—a novel pair of accuracy indices for imputed genotypes

    Dec 2022, In: BMC Bioinformatics. 23, 1, 50.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    1 Scopus citations
  • 2021

    A Phase II Study of Telisotuzumab Vedotin in Patients With c–MET-positive Stage IV or Recurrent Squamous Cell Lung Cancer (LUNG-MAP Sub-study S1400K, NCT03574753)

    Waqar, S. N., Redman, M. W., Arnold, S. M., Hirsch, F. R., Mack, P. C., Schwartz, L. H., Gandara, D. R., Stinchcombe, T. E., Leighl, N. B., Ramalingam, S. S., Tanna, S. H., Raddin, R. S., Minichiello, K., Bradley, J. D., Kelly, K., Herbst, R. S. & Papadimitrakopoulou, V. A., May 2021, In: Clinical Lung Cancer. 22, 3, p. 170-177 8 p.

    Research output: Contribution to journalArticlepeer-review

    12 Scopus citations
  • Assessing lung cancer absolute risk trajectory based on a polygenic risk model

    Hung, R. J., Warkentin, M. T., Brhane, Y., Chatterjee, N., Christiani, D. C., Landi, M. T., Caporaso, N. E., Liu, G., Johansson, M., Albanes, D., Marchand, L. L., Tardon, A., Rennert, G., Bojesen, S. E., Chen, C., Field, J. K., Kiemeney, L. A., Lazarus, P., Zienolddiny, S., Lam, S., & 9 othersAndrew, A. S., Arnold, S. M., Aldrich, M. C., Bickeboller, H., Risch, A., Schabath, M. B., McKay, J. D., Brennan, P. & Amos, C. I., Mar 2021, In: Cancer Research. 81, 6, p. 1607-1615 9 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    13 Scopus citations
  • Causal relationships between body mass index, smoking and lung cancer: Univariable and multivariable Mendelian randomization

    Zhou, W., Liu, G., Hung, R. J., Haycock, P. C., Aldrich, M. C., Andrew, A. S., Arnold, S. M., Bickeböller, H., Bojesen, S. E., Brennan, P., Brunnström, H., Melander, O., Caporaso, N. E., Landi, M. T., Chen, C., Goodman, G. E., Christiani, D. C., Cox, A., Field, J. K., Johansson, M., & 12 othersKiemeney, L. A., Lam, S., Lazarus, P., Le Marchand, L., Rennert, G., Risch, A., Schabath, M. B., Shete, S. S., Tardón, A., Zienolddiny, S., Shen, H. & Amos, C. I., Mar 1 2021, In: International Journal of Cancer. 148, 5, p. 1077-1086 10 p.

    Research output: Contribution to journalArticlepeer-review

    24 Scopus citations
  • Comprehensive functional annotation of susceptibility variants identifies genetic heterogeneity between lung adenocarcinoma and squamous cell carcinoma

    Qin, N., Li, Y., Wang, C., Zhu, M., Dai, J., Hong, T., Albanes, D., Lam, S., Tardon, A., Chen, C., Goodman, G., Bojesen, S. E., Landi, M. T., Johansson, M., Risch, A., Wichmann, H. E., Bickeboller, H., Rennert, G., Arnold, S., Brennan, P., & 24 othersField, J. K., Shete, S., Le Marchand, L., Melander, O., Brunnstrom, H., Liu, G., Hung, R. J., Andrew, A., Kiemeney, L. A., Zienolddiny, S., Grankvist, K., Johansson, M., Caporaso, N., Woll, P., Lazarus, P., Schabath, M. B., Aldrich, M. C., Stevens, V. L., Jin, G., Christiani, D. C., Hu, Z., Amos, C. I., Ma, H. & Shen, H., Apr 2021, In: Frontiers of Medicine. 15, 2, p. 275-291 17 p.

    Research output: Contribution to journalArticlepeer-review

    8 Scopus citations
  • Description of a Lung Cancer Hotspot: Disparities in Lung Cancer Histology, Incidence, and Survival in Kentucky and Appalachian Kentucky

    Brainson, C. F., Huang, B., Chen, Q., McLouth, L. E., He, C., Hao, Z., Arnold, S. M., Zinner, R. G., Mullett, T. W., Bocklage, T. J., Orren, D. K., Villano, J. L. & Durbin, E. B., Nov 2021, In: Clinical Lung Cancer. 22, 6, p. e911-e920

    Research output: Contribution to journalArticlepeer-review

    1 Scopus citations
  • Genome-wide association meta-analysis identifies pleiotropic risk loci for aerodigestive squamous cell cancers

    Lesseur, C., Ferreiro-Iglesias, A., McKay, J. D., Bossé, Y., Johansson, M., Gaborieau, V., Landi, M. T., Christiani, D. C., Caporaso, N. C., Bojesen, S. E., Amos, C. I., Shete, S., Liu, G., Rennert, G., Albanes, D., Aldrich, M. C., Tardon, A., Chen, C., Triantafillos, L., Field, J. K., & 33 othersTeare, M. D., Kiemeney, L. A., Diergaarde, B., Ferris, R. L., Zienolddiny, S., Lam, S., Olshan, A. F., Weissler, M. C., Lacko, M., Risch, A., Bickeböller, H., Ness, A. R., Thomas, S., Le Marchand, L., Schabath, M. B., Wünsch-Filho, V., Tajara, E. H., Andrew, A. S., Clifford, G. M., Lazarus, P., Grankvist, K., Johansson, M., Arnold, S., Melander, O., Brunnström, H., Boccia, S., Cadoni, G., Timens, W., Obeidat, M., Xiao, X., Houlston, R. S., Hung, R. J. & Brennan, P., Mar 5 2021, In: PLoS Genetics. 17, 3, e1009254.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    5 Scopus citations
  • Integration of multiomic annotation data to prioritize and characterize inflammation and immune-related risk variants in squamous cell lung cancer

    Sun, R., Xu, M., Li, X., Gaynor, S., Zhou, H., Li, Z., Bossé, Y., Lam, S., Tsao, M. S., Tardon, A., Chen, C., Doherty, J., Goodman, G., Bojesen, S. E., Landi, M. T., Johansson, M., Field, J. K., Bickeböller, H., Wichmann, H. E., Risch, A., & 31 othersRennert, G., Arnold, S., Wu, X., Melander, O., Brunnström, H., Le Marchand, L., Liu, G., Andrew, A., Duell, E., Kiemeney, L. A., Shen, H., Haugen, A., Johansson, M., Grankvist, K., Caporaso, N., Woll, P., Dawn Teare, M., Scelo, G., Hong, Y. C., Yuan, J. M., Lazarus, P., Schabath, M. B., Aldrich, M. C., Albanes, D., Mak, R., Barbie, D., Brennan, P., Hung, R. J., Amos, C. I., Christiani, D. C. & Lin, X., Feb 2021, In: Genetic Epidemiology. 45, 1, p. 99-114 16 p.

    Research output: Contribution to journalArticlepeer-review

    2 Scopus citations
  • MYBL2-Driven Transcriptional Programs Link Replication Stress and Error-prone DNA Repair With Genomic Instability in Lung Adenocarcinoma

    Morris, B. B., Wages, N. A., Grant, P. A., Stukenberg, P. T., Gentzler, R. D., Hall, R. D., Akerley, W. L., Varghese, T. K., Arnold, S. M., Williams, T. M., Coppola, V., Jones, D. R., Auble, D. T. & Mayo, M. W., Jan 8 2021, In: Frontiers in Oncology. 10, 585551.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    3 Scopus citations
  • Pediatric patient with peritoneal mesothelioma harboring ALK rearrangement

    Patel, R. A., Lin, M., Harper, M. M., Beck, S. J., Dietrich, C. S., Kolesar, J. M., Arnold, S. M., Hahn, J., Pandalai, P. K., Qasem, S. A. & Kim, J., Dec 2021, In: Current Problems in Cancer: Case Reports. 4, 100074.

    Research output: Contribution to journalArticlepeer-review

    Open Access
  • Real world clinicopathologic observations of patients with metastatic solid tumors receiving immune checkpoint inhibitor therapy: Analysis from Kentucky Cancer Registry

    Jacob, A., Wu, J., Kolesar, J., Durbin, E., Mathew, A., Arnold, S. & Chauhan, A., Mar 2021, In: Cancer Medicine. 10, 6, p. 2054-2062 9 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    1 Scopus citations
  • Real-world evaluation of universal germline screening for cancer treatment-relevant pharmacogenes

    Hutchcraft, M. L., Lin, N., Zhang, S., Sears, C., Zachloski, K., Belcher, E. A., Durbin, E. B., Villano, J. L., Cavnar, M. J., Arnold, S. M., Ueland, F. R. & Kolesar, J. M., Sep 2021, In: Cancers. 13, 18, 4524.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    2 Scopus citations
  • 2020

    A new efficient method to detect genetic interactions for lung cancer GWAS

    Luyapan, J., Ji, X., Li, S., Xiao, X., Zhu, D., Duell, E. J., Christiani, D. C., Schabath, M. B., Arnold, S. M., Zienolddiny, S., Brunnström, H., Melander, O., Thornquist, M. D., MacKenzie, T. A., Amos, C. I. & Gui, J., Dec 1 2020, In: BMC Medical Genomics. 13, 1, 162.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    1 Scopus citations
  • Association analysis of driver gene⇓related genetic variants identified novel lung cancer susceptibility loci with 20,871 lung cancer cases and 15,971 controls

    Wang, Y., Gorlova, O. Y., Gorlov, I. P., Zhu, M., Dai, J., Albanes, D., Lam, S., Tardon, A., Chen, C., Goodman, G. E., Bojesen, S. E., Landi, M. T., Johansson, M., Risch, A., Wichmann, H. E., Bickeboller, H., Christiani, D. C., Rennert, G., Arnold, S. M., Brennan, P., & 23 othersField, J. K., Shete, S., Le Marchand, L., Melander, O., Brunnstrom, H., Liu, G., Hung, R. J., Andrew, A. S., Kiemeney, L. A., Zienolddiny, S., Grankvist, K., Johansson, M., Caporaso, N. E., Woll, P. J., Lazarus, P., Schabath, M. B., Aldrich, M. C., Stevens, V. L., Ma, H., Jin, G., Hu, Z., Amos, C. I. & Shen, H., Jul 2020, In: Cancer Epidemiology Biomarkers and Prevention. 29, 7, p. 1423-1429 7 p.

    Research output: Contribution to journalArticlepeer-review

    3 Scopus citations
  • EGFR testing and erlotinib use in non-small cell lung cancer patients in Kentucky

    Larson, K. L., Huang, B., Chen, Q., Tucker, T., Schuh, M., Arnold, S. M. & Kolesar, J. M., Aug 2020, In: PLoS ONE. 15, 8 August, e0237790.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    4 Scopus citations
  • Evaluation of antioxidant network proteins as novel prognostic biomarkers for head and neck cancer patients

    Wicker, C. A., Takiar, V., Suganya, R., Arnold, S. M., Brill, Y. M., Chen, L., Horbinski, C. M., Napier, D., Valentino, J., Kudrimoti, M. R., Yu, G. & Izumi, T., Dec 2020, In: Oral Oncology. 111, 104949.

    Research output: Contribution to journalArticlepeer-review

    5 Scopus citations
  • Genome-wide association study of INDELs identified four novel susceptibility loci associated with lung cancer risk

    Dai, J., Huang, M., Amos, C. I., Hung, R. J., Tardon, A., Andrew, A., Chen, C., Christiani, D. C., Albanes, D., Rennert, G., Fan, J., Goodman, G., Liu, G., Field, J. K., Grankvist, K., Kiemeney, L. A., Le Marchand, L., Schabath, M. B., Johansson, M., Aldrich, M. C., & 19 othersJohansson, M., Caporaso, N., Lazarus, P., Lam, S., Bojesen, S. E., Arnold, S., Landi, M. T., Risch, A., Wichmann, H. E., Bickeboller, H., Brennan, P., Shete, S., Melander, O., Brunnstrom, H., Zienolddiny, S., Woll, P., Stevens, V., Hu, Z. & Shen, H., May 15 2020, In: International Journal of Cancer. 146, 10, p. 2855-2864 10 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    7 Scopus citations
  • Immune-mediated genetic pathways resulting in pulmonary function impairment increase lung cancer susceptibility

    Kachuri, L., Johansson, M., Rashkin, S. R., Graff, R. E., Bossé, Y., Manem, V., Caporaso, N. E., Landi, M. T., Christiani, D. C., Vineis, P., Liu, G., Scelo, G., Zaridze, D., Shete, S. S., Albanes, D., Aldrich, M. C., Tardón, A., Rennert, G., Chen, C., Goodman, G. E., & 31 othersDoherty, J. A., Bickeböller, H., Field, J. K., Davies, M. P., Dawn Teare, M., Kiemeney, L. A., Bojesen, S. E., Haugen, A., Zienolddiny, S., Lam, S., Le Marchand, L., Cheng, I., Schabath, M. B., Duell, E. J., Andrew, A. S., Manjer, J., Lazarus, P., Arnold, S., McKay, J. D., Emami, N. C., Warkentin, M. T., Brhane, Y., Obeidat, M., Martin, R. M., Relton, C., Davey Smith, G., Haycock, P. C., Amos, C. I., Brennan, P., Witte, J. S. & Hung, R. J., Dec 1 2020, In: Nature Communications. 11, 1, 27.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    7 Scopus citations
  • Phase II Trial of Carfilzomib Plus Irinotecan in Patients With Small-cell Lung Cancer Who Have Progressed on Prior Platinum-based Chemotherapy

    Arnold, S. M., Chansky, K., Baggstrom, M. Q., Thompson, M. A., Sanborn, R. E., Villano, J. L., Waqar, S. N., Hamm, J., Leggas, M., Willis, M., Rosales, J. & Crowley, J. J., Jul 2020, In: Clinical Lung Cancer. 21, 4, p. 357-364.e7

    Research output: Contribution to journalArticlepeer-review

    4 Scopus citations
  • Protein-altering germline mutations implicate novel genes related to lung cancer development

    Ji, X., Mukherjee, S., Landi, M. T., Bosse, Y., Joubert, P., Zhu, D., Gorlov, I., Xiao, X., Han, Y., Gorlova, O., Hung, R. J., Brhane, Y., Carreras-Torres, R., Christiani, D. C., Caporaso, N., Johansson, M., Liu, G., Bojesen, S. E., Le Marchand, L., Albanes, D., & 91 othersBickeböller, H., Aldrich, M. C., Bush, W. S., Tardon, A., Rennert, G., Chen, C., Byun, J., Dragnev, K. H., Field, J. K., Kiemeney, L. F., Lazarus, P., Zienolddiny, S., Lam, S., Schabath, M. B., Andrew, A. S., Bertazzi, P. A., Pesatori, A. C., Diao, N., Su, L., Song, L., Zhang, R., Leighl, N., Johansen, J. S., Mellemgaard, A., Saliba, W., Haiman, C., Wilkens, L., Fernandez-Somoano, A., Fernandez-Tardon, G., Heijden, E. H. F. M. V. D., Kim, J. H., Davies, M. P. A., Marcus, M. W., Brunnström, H., Manjer, J., Melander, O., Muller, D. C., Overvad, K., Trichopoulou, A., Tumino, R., Goodman, G. E., Cox, A., Taylor, F., Woll, P., Wichmann, E., Muley, T., Risch, A., Rosenberger, A., Grankvist, K., Johansson, M., Shepherd, F., Tsao, M. S., Arnold, S. M., Haura, E. B., Bolca, C., Holcatova, I., Janout, V., Kontic, M., Lissowska, J., Mukeria, A., Ognjanovic, S., Orlowski, T. M., Scelo, G., Swiatkowska, B., Zaridze, D., Bakke, P., Skaug, V., Butler, L. M., Offit, K., Srinivasan, P., Bandlamudi, C., Hellmann, M. D., Solit, D. B., Robson, M. E., Rudin, C. M., Stadler, Z. K., Taylor, B. S., Berger, M. F., Houlston, R., McLaughlin, J., Stevens, V., Nickle, D. C., Obeidat, M., Timens, W., Artigas, M. S., Shete, S., Brenner, H., Chanock, S., Brennan, P., McKay, J. D. & Amos, C. I., Dec 1 2020, In: Nature Communications. 11, 1, 2220.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    12 Scopus citations
  • Transcriptome-wide association study reveals candidate causal genes for lung cancer

    Bossé, Y., Li, Z., Xia, J., Manem, V., Carreras-Torres, R., Gabriel, A., Gaudreault, N., Albanes, D., Aldrich, M. C., Andrew, A., Arnold, S., Bickeböller, H., Bojesen, S. E., Brennan, P., Brunnstrom, H., Caporaso, N., Chen, C., Christiani, D. C., Field, J. K., Goodman, G., & 28 othersGrankvist, K., Houlston, R., Johansson, M., Johansson, M., Kiemeney, L. A., Lam, S., Landi, M. T., Lazarus, P., Le Marchand, L., Liu, G., Melander, O., Rennert, G., Risch, A., Rosenberg, S. M., Schabath, M. B., Shete, S., Song, Z., Stevens, V. L., Tardon, A., Wichmann, H. E., Woll, P., Zienolddiny, S., Obeidat, M., Timens, W., Hung, R. J., Joubert, P., Amos, C. I. & McKay, J. D., Apr 1 2020, In: International Journal of Cancer. 146, 7, p. 1862-1878 17 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    12 Scopus citations
  • Using residential histories in case-control analysis of lung cancer and mountaintop removal coal mining in Central Appalachia

    Christian, W. J., Walker, C. J., Huang, B., Levy, J. E., Durbin, E. & Arnold, S., Nov 2020, In: Spatial and Spatio-temporal Epidemiology. 35, 100364.

    Research output: Contribution to journalArticlepeer-review

    1 Scopus citations
  • 2019

    A case-control study of trace-element status and lung cancer in Appalachian Kentucky

    Unrine, J. M., Slone, S. A., Sanderson, W., Johnson, N., Durbin, E. B., Shrestha, S., Hahn, E. J., Feltner, F., Huang, B., Christian, W. J., Mellon, I., Orren, D. K. & Arnold, S. M., Feb 2019, In: PLoS ONE. 14, 2, e0212340.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    9 Scopus citations
  • A probabilistic method for leveraging functional annotations to enhance estimation of the temporal order of pathway mutations during carcinogenesis

    Wang, M., Yu, T., Liu, J., Chen, L., Stromberg, A. J., Villano, J. L., Arnold, S. M., Liu, C. & Wang, C., Dec 2 2019, In: BMC Bioinformatics. 20, 1, 620.

    Research output: Contribution to journalArticlepeer-review

    Open Access
  • Characterization of squamous cell lung cancers from Appalachian Kentucky

    Liu, J., Murali, T., Yu, T., Liu, C., Sivakumaran, T. A., Moseley, H. N. B., Zhulin, I. B., Weiss, H. L., Durbin, E. B., Ellingson, S. R., Liu, J., Huang, B., Hallahan, B. J., Horbinski, C. M., Hodges, K., Napier, D. L., Bocklage, T., Mueller, J., Vanderford, N. L., Fardo, D. W., & 2 othersWang, C. & Arnold, S. M., Feb 2019, In: Cancer Epidemiology Biomarkers and Prevention. 28, 2, p. 348-356 9 p.

    Research output: Contribution to journalArticlepeer-review

    3 Scopus citations
  • Cross-registry neural domain adaptation to extract mutational test results from pathology reports

    Rios, A., Durbin, E. B., Hands, I., Arnold, S. M., Shah, D., Schwartz, S. M., Goulart, B. H. L. & Kavuluru, R., Sep 2019, In: Journal of Biomedical Informatics. 97, 103267.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    2 Scopus citations
  • Elevated platelet count appears to be causally associated with increased risk of lung cancer: A mendelian randomization analysis

    Zhu, Y., Wei, Y., Zhang, R., Dong, X., Shen, S., Zhao, Y., Bai, J., Albanes, D., Caporaso, N. E., Landi, M. T., Zhu, B., Chanock, S. J., Gu, F., Lam, S., Tsao, M. S., Shepherd, F. A., Tardon, A., Fernandez-Somoano, A., Fernandez-Tardon, G., Chen, C., & 57 othersBarnett, M. J., Doherty, J., Bojesen, S. E., Johansson, M., Brennan, P., McKay, J. D., Carreras-Torres, R., Muley, T., Risch, A., Wichmann, H. E., Bickeboeller, H., Rosenberger, A., Rennert, G., Saliba, W., Arnold, S. M., Field, J. K., Davies, M. P. A., Marcus, M. W., Wu, X., Ye, Y., Le Marchand, L., Wilkens, L. R., Melander, O., Manjer, J., Brunnstrom, H., Hung, R. J., Liu, G., Brhane, Y., Kachuri, L., Andrew, A. S., Duell, E. J., Kiemeney, L. A., Van der Heijden, E. H. F. M., Haugen, A., Zienolddiny, S., Skaug, V., Grankvist, K., Johansson, M., Woll, P. J., Cox, A., Taylor, F., Teare, D. M., Lazarus, P., Schabath, M. B., Aldrich, M. C., Houlston, R. S., McLaughlin, J., Stevens, V. L., Shen, H., Hu, Z., Dai, J., Amos, C. I., Han, Y., Zhu, D., Goodman, G. E., Chen, F. & Christiani, D. C., May 2019, In: Cancer Epidemiology Biomarkers and Prevention. 28, 5, p. 935-942 8 p.

    Research output: Contribution to journalArticlepeer-review

    17 Scopus citations
  • Genetic interaction analysis among oncogenesis-related genes revealed novel genes and networks in lung cancer development

    Li, Y., Xiao, X., Bossé, Y., Gorlova, O., Gorlov, I., Han, Y., Byun, J., Leighl, N., Johansen, J. S., Barnett, M., Chen, C., Goodman, G., Cox, A., Taylor, F., Woll, P., Erich Wichmann, H., Manz, J., Muley, T., Risch, A., Rosenberger, A., & 60 othersHan, J., Siminovitch, K., Arnold, S. M., Haura, E. B., Bolca, C., Holcatova, I., Janout, V., Kontic, M., Lissowska, J., Mukeria, A., Ognjanovic, S., Orlowski, T. M., Scelo, G., Swiatkowska, B., Zaridze, D., Bakke, P., Skaug, V., Zienolddiny, S., Duell, E. J., Butler, L. M., Houlston, R., Artigas, M. S., Grankvist, K., Johansson, M., Shepherd, F. A., Marcus, M. W., Brunnström, H., Manjer, J., Melander, O., Muller, D. C., Overvad, K., Trichopoulou, A., Tumino, R., Liu, G., Bojesen, S. E., Wu, X., Le Marchand, L., Albanes, D., Bickeböller, H., Aldrich, M. C., Bush, W. S., Tardon, A., Rennert, G., Dawn Teare, M., Field, J. K., Kiemeney, L. A., Lazarus, P., Haugen, A., Lam, S., Schabath, M. B., Andrew, A. S., Bertazzi, P. A., Pesatori, A. C., Christiani, D. C., Caporaso, N., Johansson, M., McKay, J. D., Brennan, P., Hung, R. J. & Amos, C. I., Mar 1 2019, In: Oncotarget. 10, 19, p. 1760-1774 15 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    13 Scopus citations
  • Integrating a 92-gene expression analysis for the management of neuroendocrine tumors of unknown primary

    Chauhan, A., Farooqui, Z., Silva, S. R., Murray, L. A., Hodges, K. B., Yu, Q., Myint, Z. W., Raajesekar, A. K., Weiss, H., Arnold, S., Mark Evers, B. & Anthony, L., Jan 1 2019, In: Asian Pacific Journal of Cancer Prevention. 20, 1, p. 113-116 4 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    4 Scopus citations
  • Is high vitamin B12 status a cause of lung cancer?

    Sep 15 2019, In: International Journal of Cancer. 145, 6, p. 1499-1503 5 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    44 Scopus citations
  • Lung Cancer Risk in Never-Smokers of European Descent is Associated With Genetic Variation in the 5p15.33 TERT-CLPTM1Ll Region

    Hung, R. J., Spitz, M. R., Houlston, R. S., Schwartz, A. G., Field, J. K., Ying, J., Li, Y., Han, Y., Ji, X., Chen, W., Wu, X., Gorlov, I. P., Na, J., de Andrade, M., Liu, G., Brhane, Y., Diao, N., Wenzlaff, A., Davies, M. P. A., Liloglou, T., & 46 othersTimofeeva, M., Muley, T., Rennert, H., Saliba, W., Ryan, B. M., Bowman, E., Barros-Dios, J. M., Pérez-Ríos, M., Morgenstern, H., Zienolddiny, S., Skaug, V., Ugolini, D., Bonassi, S., van der Heijden, E. H. F. M., Tardon, A., Bojesen, S. E., Landi, M. T., Johansson, M., Bickeböller, H., Arnold, S., Le Marchand, L., Melander, O., Andrew, A., Grankvist, K., Caporaso, N., Teare, M. D., Schabath, M. B., Aldrich, M. C., Kiemeney, L. A., Wichmann, H. E., Lazarus, P., Mayordomo, J., Neri, M., Haugen, A., Zhang, Z. F., Ruano-Raviña, A., Brenner, H., Harris, C. C., Orlow, I., Rennert, G., Risch, A., Brennan, P., Christiani, D. C., Amos, C. I., Yang, P. & Gorlova, O. Y., Aug 2019, In: Journal of Thoracic Oncology. 14, 8, p. 1360-1369 10 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    15 Scopus citations
  • Mendelian Randomization and mediation analysis of leukocyte telomere length and risk of lung and head and neck cancers

    Kachuri, L., Saarela, O., Bojesen, S. E., Davey Smith, G., Liu, G., Landi, M. T., Caporaso, N. E., Christiani, D. C., Johansson, M., Panico, S., Overvad, K., Trichopoulou, A., Vineis, P., Scelo, G., Zaridze, D., Wu, X., Albanes, D., Diergaarde, B., Lagiou, P., Macfarlane, G. J., & 50 othersAldrich, M. C., Tardón, A., Rennert, G., Olshan, A. F., Weissler, M. C., Chen, C., Goodman, G. E., Doherty, J. A., Ness, A. R., Bickeböller, H., Wichmann, H. E., Risch, A., Field, J. K., Teare, M. D., Kiemeney, L. A., Van Der Heijden, E. H. F. M., Carroll, J. C., Haugen, A., Zienolddiny, S., Skaug, V., Wünsch-Filho, V., Tajara, E. H., Ayoub Moysés, R., Daumas Nunes, F., Lam, S., Eluf-Neto, J., Lacko, M., Peters, W. H. M., Le Marchand, L., Duell, E. J., Andrew, A. S., Franceschi, S., Schabath, M. B., Manjer, J., Arnold, S., Lazarus, P., Mukeriya, A., Swiatkowska, B., Janout, V., Holcatova, I., Stojsic, J., Mates, D., Lissowska, J., Boccia, S., Lesseur, C., Zong, X., McKay, J. D., Brennan, P., Amos, C. I. & Hung, R. J., Jun 1 2019, In: International Journal of Epidemiology. 48, 3, p. 751-766 16 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    14 Scopus citations
  • Outcomes in surgically resectable oropharynx cancer treated with transoral robotic surgery versus definitive chemoradiation

    Dhanireddy, B., Burnett, N. P., Sanampudi, S., Wooten, C. E., Slezak, J., Shelton, B., Shelton, L., Shearer, A., Arnold, S., Kudrimoti, M. & Gal, T. J., Sep 1 2019, In: American Journal of Otolaryngology - Head and Neck Medicine and Surgery. 40, 5, p. 673-677 5 p.

    Research output: Contribution to journalArticlepeer-review

    18 Scopus citations
  • Pharmacogenomic potential in advanced cancer patients

    Nichols, D., Arnold, S., Weiss, H. L., Wu, J., Durbin, E. B., Miller, R. & Kolesar, J., Mar 19 2019, In: American Journal of Health-System Pharmacy. 76, 7, p. 415-423 9 p.

    Research output: Contribution to journalArticlepeer-review

    5 Scopus citations
  • Population pharmacokinetic analysis of AR-67, a lactone stable camptothecin analogue, in cancer patients with solid tumors

    Tang, F., Tsakalozou, E., Arnold, S. M., Ng, C. M. & Leggas, M., Dec 1 2019, In: Investigational New Drugs. 37, 6, p. 1218-1230 13 p.

    Research output: Contribution to journalArticlepeer-review

    1 Scopus citations
  • SDA: A semi-parametric differential abundance analysis method for metabolomics and proteomics data

    Li, Y., Fan, T. W. M., Lane, A. N., Kang, W. Y., Arnold, S. M., Stromberg, A. J., Wang, C. & Chen, L., Oct 17 2019, In: BMC Bioinformatics. 20, 1, 501.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    3 Scopus citations
  • Shared heritability and functional enrichment across six solid cancers

    Jiang, X., Finucane, H. K., Schumacher, F. R., Schmit, S. L., Tyrer, J. P., Han, Y., Michailidou, K., Lesseur, C., Kuchenbaecker, K. B., Dennis, J., Conti, D. V., Casey, G., Gaudet, M. M., Huyghe, J. R., Albanes, D., Aldrich, M. C., Andrew, A. S., Andrulis, I. L., Anton-Culver, H., Antoniou, A. C., & 313 othersAntonenkova, N. N., Arnold, S. M., Aronson, K. J., Arun, B. K., Bandera, E. V., Barkardottir, R. B., Barnes, D. R., Batra, J., Beckmann, M. W., Benitez, J., Benlloch, S., Berchuck, A., Berndt, S. I., Bickeböller, H., Bien, S. A., Blomqvist, C., Boccia, S., Bogdanova, N. V., Bojesen, S. E., Bolla, M. K., Brauch, H., Brenner, H., Brenton, J. D., Brook, M. N., Brunet, J., Brunnström, H., Buchanan, D. D., Burwinkel, B., Butzow, R., Cadoni, G., Caldés, T., Caligo, M. A., Campbell, I., Campbell, P. T., Cancel-Tassin, G., Cannon-Albright, L., Campa, D., Caporaso, N., Carvalho, A. L., Chan, A. T., Chang-Claude, J., Chanock, S. J., Chen, C., Christiani, D. C., Claes, K. B. M., Claessens, F., Clements, J., Collée, J. M., Correa, M. C., Couch, F. J., Cox, A., Cunningham, J. M., Cybulski, C., Czene, K., Daly, M. B., deFazio, A., Devilee, P., Diez, O., Gago-Dominguez, M., Donovan, J. L., Dörk, T., Duell, E. J., Dunning, A. M., Dwek, M., Eccles, D. M., Edlund, C. K., Edwards, D. R. V., Ellberg, C., Evans, D. G., Fasching, P. A., Ferris, R. L., Liloglou, T., Figueiredo, J. C., Fletcher, O., Fortner, R. T., Fostira, F., Franceschi, S., Friedman, E., Gallinger, S. J., Ganz, P. A., Garber, J., García-Sáenz, J. A., Gayther, S. A., Giles, G. G., Godwin, A. K., Goldberg, M. S., Goldgar, D. E., Goode, E. L., Goodman, M. T., Goodman, G., Grankvist, K., Greene, M. H., Gronberg, H., Gronwald, J., Guénel, P., Håkansson, N., Hall, P., Hamann, U., Hamdy, F. C., Hamilton, R. J., Hampe, J., Haugen, A., Heitz, F., Herrero, R., Hillemanns, P., Hoffmeister, M., Høgdall, E., Hong, Y. C., Hopper, J. L., Houlston, R., Hulick, P. J., Hunter, D. J., Huntsman, D. G., Idos, G., Imyanitov, E. N., Ingles, S. A., Isaacs, C., Jakubowska, A., James, P., Jenkins, M. A., Johansson, M., Johansson, M., John, E. M., Joshi, A. D., Kaneva, R., Karlan, B. Y., Kelemen, L. E., Kühl, T., Khaw, K. T., Khusnutdinova, E., Kibel, A. S., Kiemeney, L. A., Kim, J., Kjaer, S. K., Knight, J. A., Kogevinas, M., Kote-Jarai, Z., Koutros, S., Kristensen, V. N., Kupryjanczyk, J., Lacko, M., Lam, S., Lambrechts, D., Landi, M. T., Lazarus, P., Le, N. D., Lee, E., Lejbkowicz, F., Lenz, H. J., Leslie, G., Lessel, D., Lester, J., Levine, D. A., Li, L., Li, C. I., Lindblom, A., Lindor, N. M., Liu, G., Loupakis, F., Lubiński, J., Maehle, L., Maier, C., Mannermaa, A., Marchand, L. L., Margolin, S., May, T., McGuffog, L., Meindl, A., Middha, P., Miller, A., Milne, R. L., MacInnis, R. J., Modugno, F., Montagna, M., Moreno, V., Moysich, K. B., Mucci, L., Muir, K., Mulligan, A. M., Nathanson, K. L., Neal, D. E., Ness, A. R., Neuhausen, S. L., Nevanlinna, H., Newcomb, P. A., Newcomb, L. F., Nielsen, F. C., Nikitina-Zake, L., Nordestgaard, B. G., Nussbaum, R. L., Offit, K., Olah, E., Olama, A. A. A., Olopade, O. I., Olshan, A. F., Olsson, H., Osorio, A., Pandha, H., Park, J. Y., Pashayan, N., Parsons, M. T., Pejovic, T., Penney, K. L., Peters, W. H. M., Phelan, C. M., Phipps, A. I., Plaseska-Karanfilska, D., Pring, M., Prokofyeva, D., Radice, P., Stefansson, K., Ramus, S. J., Raskin, L., Rennert, G., Rennert, H. S., van Rensburg, E. J., Riggan, M. J., Risch, H. A., Risch, A., Roobol, M. J., Rosenstein, B. S., Rossing, M. A., De Ruyck, K., Saloustros, E., Sandler, D. P., Sawyer, E. J., Schabath, M. B., Schleutker, J., Schmidt, M. K., Setiawan, V. W., Shen, H., Siegel, E. M., Sieh, W., Singer, C. F., Slattery, M. L., Sorensen, K. D., Southey, M. C., Spurdle, A. B., Stanford, J. L., Stevens, V. L., Stintzing, S., Stone, J., Sundfeldt, K., Sutphen, R., Swerdlow, A. J., Tajara, E. H., Tangen, C. M., Tardon, A., Taylor, J. A., Teare, M. D., Teixeira, M. R., Terry, M. B., Terry, K. L., Thibodeau, S. N., Thomassen, M., Bjørge, L., Tischkowitz, M., Toland, A. E., Torres, D., Townsend, P. A., Travis, R. C., Tung, N., Tworoger, S. S., Ulrich, C. M., Usmani, N., Vachon, C. M., Van Nieuwenhuysen, E., Vega, A., Aguado-Barrera, M. E., Wang, Q., Webb, P. M., Weinberg, C. R., Weinstein, S., Weissler, M. C., Weitzel, J. N., West, C. M. L., White, E., Whittemore, A. S., Wichmann, H. E., Wiklund, F., Winqvist, R., Wolk, A., Woll, P., Woods, M., Wu, A. H., Wu, X., Yannoukakos, D., Zheng, W., Zienolddiny, S., Ziogas, A., Zorn, K. K., Lane, J. M., Saxena, R., Thomas, D., Hung, R. J., Diergaarde, B., McKay, J., Peters, U., Hsu, L., García-Closas, M., Eeles, R. A., Chenevix-Trench, G., Brennan, P. J., Haiman, C. A., Simard, J., Easton, D. F., Gruber, S. B., Pharoah, P. D. P., Price, A. L., Pasaniuc, B., Amos, C. I., Kraft, P. & Lindström, S., Dec 1 2019, In: Nature Communications. 10, 1, 431.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    49 Scopus citations
  • Spatiotemporal Analysis of Lung Cancer Histological Types in Kentucky, 1995–2014

    Christian, W. J., Vanderford, N. L., McDowell, J., Huang, B., Durbin, E. B., Absher, K. J., Walker, C. J. & Arnold, S. M., Jan 1 2019, In: Cancer Control. 26, 1

    Research output: Contribution to journalArticlepeer-review

    Open Access
    5 Scopus citations
  • Systematic analyses of regulatory variants in DNase i hypersensitive sites identified two novel lung cancer susceptibility loci

    Dai, J., Li, Z., Amos, C. I., Hung, R. J., Tardon, A., Andrew, A. S., Chen, C., Christiani, D. C., Albanes, D., Van Der Heijden, E. H. F. M., Duell, E. J., Rennert, G., McKay, J. D., Yuan, J. M., Field, J. K., Manjer, J., Grankvist, K., Le Marchand, L., Teare, M. D., Schabath, M. B., & 17 othersAldrich, M. C., Tsao, M. S., Lazarus, P., Lam, S., Bojesen, S. E., Arnold, S., Wu, X., Haugen, A., Janout, V., Johansson, M., Brhane, Y., Fernandez-Somoano, A., Kiemeney, L. A., Davies, M. P. A., Zienolddiny, S., Hu, Z. & Shen, H., May 14 2019, In: Carcinogenesis. 40, 3, p. 432-440 9 p., bgy187.

    Research output: Contribution to journalArticlepeer-review

    3 Scopus citations
  • Validity of natural language processing for ascertainment of EGFR and ALK test results in SEER cases of stage IV non–small-cell lung cancer

    Goulart, B. H. L., Silgard, E. T., Baik, C. S., Bansal, A., Sun, Q., Durbin, E. B., Hands, I., Shah, D., Arnold, S. M., Ramsey, S. D., Kavuluru, R. & Schwartz, S. M., 2019, In: JCO clinical cancer informatics. 3, p. 1-15 15 p.

    Research output: Contribution to journalArticlepeer-review

    3 Scopus citations
  • 2018

    Capecitabine and Temozolomide in Neuroendocrine Tumor of Unknown Primary

    Chauhan, A., Farooqui, Z., Murray, L. A., Weiss, H. L., War Myint, Z., Raajasekar, A. K. A., Evers, B. M., Arnold, S. & Anthony, L., 2018, In: Journal of Oncology. 2018, 3519247.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    8 Scopus citations
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