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1985 …2022

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Personal profile

Research Interests

My research focuses on applying systems biochemical approaches including novel Stable Isotope-Resolved Metabolomic (SIRM), metabolomics-edited transcriptomic (META), and proteomic approaches (METPA) which we have developed 1) to investigate the anticancer mechanism of natural products and novel therapeutic agents; 2) to explore the functional role(s) of tumor microenvironment and extrinsic environmental factors in cancer development, progression, and therapy; 3) to uncover novel therapeutic targets and distinct mechanism-informed biochemical marker patterns for human diseases by interrogating the human metabolome; and 4) to decipher the gene networks that govern cancer metabolism. The central tool that I have used to achieve these goals is the integration of nuclear magnetic resonance (NMR) with mass spectrometry (MS) technologies, which enables a systematic interrogation of human metabolic networks and their perturbations by diseases. 

Expertise related to UN Sustainable Development Goals

In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):

  • SDG 3 - Good Health and Well-being
  • SDG 14 - Life Below Water
  • SDG 15 - Life on Land

Education/Academic qualification

Doctor of Philosophy, Univ Of California - Davis

1983

Master of Science, Univ Of Hawaii

1979

Bachelor of Science, National Taiwan University

1977

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