Grants and Contracts Details
Description
Our subcontract from Research Triangle Institute (RTI) will determine the ability of tobacco
constituents provided by RTI to release dopamine in nucleus accumbens shell from adolescent
and adult rats. Effects of the tobacco constituents will be compared to dopamine release evoked
by nicotine. We will use in vivo microdialysis to evaluate dopamine release in the terminal
region of the midbrain cell bodies (ventral tegmental area). High performance liquid
chromatography with electrochemical detection will be used to detect dopamine in the samples.
Status | Finished |
---|---|
Effective start/end date | 8/15/14 → 3/31/16 |
Funding
- Research Triangle Institute: $682,363.00
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