Grants and Contracts Details
Description
Adults and orthodontic patients in general, desire shorter orthodontic treatment time. This
trend has led to an increased focus on methods for accelerating orthodontic tooth movement. Many of
the studies examining the mechanisms for expedited orthodontic tooth movement have been conducted
in rodents. However, one of the surprising findings in rodents is a dramatic (~62-80%) reduction in
bone volume in the inter-radicular bone concomitant with the tooth movement at 14-40 days.
Interestingly, the bone volume is restored at later time points (~60 days). While there is no
histological evidence to suggest that this loss of bone occurs in larger animal models, it still
needs additional study. As a further complication, from human radiographic studies, it appears that
molar protraction results in increased density of bone and dampens the rate of tooth movement.
However, reduced bone volume in rodents will lead to an acceleration of tooth movement due to
decreased resistance to movement and may lead to incorrect interpretation when results are
generalized to humans.
It has been proposed that the forces used to move teeth in rodents have been excessive and forces
below 25cN should be used for molar protraction. Scaling animal size from humans to rodents would
suggest that loads of
Status | Finished |
---|---|
Effective start/end date | 7/1/16 → 6/30/17 |
Funding
- American Association of Orthodontics Foundation: $5,000.00
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