Projects and Grants per year
Grants and Contracts Details
Description
Since 1968 the University of Kentucky has provided reference
tobacco products as standards for non-clinical investigational purposes by tobacco manufacturers,
contract and government laboratories, and academic institutions. This project will produce and
characterize machine made, sheet-wrapped cigar tobacco reference products representative of
large cigars (processed leaf filler, non-premium), little cigars (brown cigarettes) and small cigars
(cigarillos). These new certified reference products will be manufactured in one manufacturing run
each, to ensure product uniformity, and will have certified physical and chemical characteristics to
allow for proficiency testing, instrument calibration, employee/student training, and for method
validation and investigational purposes. A process for the design, analysis, and approval is
included to ensure input from stakeholders and that the new cigar reference tobacco products
meet the specified goals. Quality control and sample testing parameters are defined and
substantial chemical analyses will be conducted to allow for certification of product characteristics
and constituent levels.
The CTRP will advance efforts to collaborate and coordinate studies with stakeholders, including
Tobacco Centers for Regulatory Science, commercial product testing laboratories, tobacco product
manufacturers, and academic researchers. This proposal outlines significant improvements to
current cigar tobacco reference products in terms of product design and certification, product
distribution, product storage, planning for new reference tobacco products, establishing research
capability and providing new services that will benefit the tobacco research community. A webbased
interface for ordering reference tobacco products and for the secure transmission and
storage of collaborative data is under development and will be enhanced to include the cigar
reference products. The CTRP web-based solution and database will be migrated to a Cloud
environment to scale resources to meet future demand, while reducing operational costs and
increasing the effectiveness of IT processes and personnel. As an academic institution, our
proposal will be a service to the entire tobacco research community and is an improvement over
current efforts to coordinate and administer inter-laboratory comparison studies on tobacco
reference products and mechanisms to provide various cigar tobacco reference products. The
development of high-quality cigar tobacco reference products and providing those through the
CTRP will strengthen the FDA’s effort to develop the science of tobacco regulation and provide a
much needed basic resource for tobacco product research and regulation
Status | Active |
---|---|
Effective start/end date | 2/1/20 → 1/31/25 |
Funding
- Food and Drug Administration
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Projects
- 1 Active
-
Cigar Reference Products Program
Chambers, O., Fisher, A., Fisher, C., Ji, H., McNees, C., Shelton, B. & Yuan, L.
2/1/20 → 1/31/25
Project: Research project