Carotid Occlusion Surgery Study (COSS)

  • Dobbs, Michael (PI)

Grants and Contracts Details

Description

The goal of this study is to test the hypothesis that surgical anastomosis of the superficial temporal artery to the middle cerebral artery (STA-MCA), when added to best medical therapy can reduce by 40%, despite peri-operative stroke and death, subsequent ipsilateral ischemic stroke (fatal and non-fatal) at two years in participants with recently ($ 120 days) symptomatic internal carotid artery occlusion and ipsilateral increased oxygen extraction fraction measured by positron emission tomography (PET). We will test this hypothesis by conducting a randomized, non-blinded, controlled trial in 372 participants randomized equally to surgical or non-surgical treatment. ,:J
StatusFinished
Effective start/end date12/1/088/31/11

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